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The map label for this gene is galE [H]

Identifier: 52785050

GI number: 52785050

Start: 1285806

End: 1286792

Strand: Reverse

Name: galE [H]

Synonym: BLi01280

Alternate gene names: 52785050

Gene position: 1286792-1285806 (Counterclockwise)

Preceding gene: 52785051

Following gene: 52785049

Centisome position: 30.47

GC content: 52.58

Gene sequence:

>987_bases
ATGACATCCGTACTCGTAACAGGAGGAGCCGGATACATCGGCAGCCACACCGTACTCGAATTGACAAAGCAAAACCGCTC
CGTCGTCGTGCTTGACAATTTATCTACCGGACACAGGGAAGCCGTCAGCGGGGTCAGCTTTTACGAAGGCGATATCGCTG
ATGCGGCACTTGTCAAAGCCATCATCAAACATCATGATGTCGATGCTGTCATCCATTTCGCCGCCAAAAGCCTTGTGTCC
GAATCGATCGAAAAGCCTGAGATATACTTTAGGGAAAACACGCTAAAGTCTTGTGCATTTTTCGAAACGGCCATCAAGGA
AGGCGTCAATAACATCGTCTTTTCGTCAACCGCCGCCGTATACGGCATCCCGGAGAAAGCCCCGATTAAAGAGGCTGCTC
CCCTCTCCCCTGTCAATCCTTACGGGGAATCGAAGCTGATGATCGAAAAATATCTGCACTGGGTCGGAAAAACGCACGGT
GTCAAATGGGCCGCCCTCCGCTACTTCAACGCCGCCGGCGCCGCTTTAAACGGAGCGATCGGCGAGGACCACGATCCCGA
AAGCCACCTCATTCCCCTCGTCCTGCAGACGGCTTTGGGACAGCGAAAGCAGCTGTCCATTTTCGGAGAAGATTATTCGA
CGCCAGACGGAACCTGCATCAGGGATTATATTCACGTCCTCGATCTGGCTTCCGCCCACCTGGCTGCCCTTGATGGATTA
TATGAAGACAGACTGAAGCAAAATGTTTATAATGTAGGGACAGGGGCCGGACATTCCGTAAAAGAAATCATTGAAACCGC
GGAAAACATGACAGAGCGAAGCATTGCAGCAAAAACGGACGAGCGCAGAGCGGGAGATCCGCCAGTGCTGGTGGCGGACA
GCCGGACACTGGTGGAAGATACCGGATGGAAGCCGCAATACAGCGATTTGCAAACCATCATTCAAAGCGCATGGCAATGG
CACAAAGCGCATCCGGACGGTTTTTGA

Upstream 100 bases:

>100_bases
CGAGTACGGAAATCGCCCTCATGCGGGACGAGATGCGGCCAAAACTGCTCGCCTACCTGGAGAGCGTCTTAAAAAAAGAA
GCGCAGAAAGGAGCATGGCA

Downstream 100 bases:

>100_bases
GATTCGCTTATTTCCCCCGCGGGCGCCAGGGAAGCGTCCCGGCGGCTGCTCCAACGTTCGGCTGATGAAATCAAAAGCAG
GGAGAAAAAACGAAAATGGG

Product: hypothetical protein

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 328; Mature: 327

Protein sequence:

>328_residues
MTSVLVTGGAGYIGSHTVLELTKQNRSVVVLDNLSTGHREAVSGVSFYEGDIADAALVKAIIKHHDVDAVIHFAAKSLVS
ESIEKPEIYFRENTLKSCAFFETAIKEGVNNIVFSSTAAVYGIPEKAPIKEAAPLSPVNPYGESKLMIEKYLHWVGKTHG
VKWAALRYFNAAGAALNGAIGEDHDPESHLIPLVLQTALGQRKQLSIFGEDYSTPDGTCIRDYIHVLDLASAHLAALDGL
YEDRLKQNVYNVGTGAGHSVKEIIETAENMTERSIAAKTDERRAGDPPVLVADSRTLVEDTGWKPQYSDLQTIIQSAWQW
HKAHPDGF

Sequences:

>Translated_328_residues
MTSVLVTGGAGYIGSHTVLELTKQNRSVVVLDNLSTGHREAVSGVSFYEGDIADAALVKAIIKHHDVDAVIHFAAKSLVS
ESIEKPEIYFRENTLKSCAFFETAIKEGVNNIVFSSTAAVYGIPEKAPIKEAAPLSPVNPYGESKLMIEKYLHWVGKTHG
VKWAALRYFNAAGAALNGAIGEDHDPESHLIPLVLQTALGQRKQLSIFGEDYSTPDGTCIRDYIHVLDLASAHLAALDGL
YEDRLKQNVYNVGTGAGHSVKEIIETAENMTERSIAAKTDERRAGDPPVLVADSRTLVEDTGWKPQYSDLQTIIQSAWQW
HKAHPDGF
>Mature_327_residues
TSVLVTGGAGYIGSHTVLELTKQNRSVVVLDNLSTGHREAVSGVSFYEGDIADAALVKAIIKHHDVDAVIHFAAKSLVSE
SIEKPEIYFRENTLKSCAFFETAIKEGVNNIVFSSTAAVYGIPEKAPIKEAAPLSPVNPYGESKLMIEKYLHWVGKTHGV
KWAALRYFNAAGAALNGAIGEDHDPESHLIPLVLQTALGQRKQLSIFGEDYSTPDGTCIRDYIHVLDLASAHLAALDGLY
EDRLKQNVYNVGTGAGHSVKEIIETAENMTERSIAAKTDERRAGDPPVLVADSRTLVEDTGWKPQYSDLQTIIQSAWQWH
KAHPDGF

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=343, Percent_Identity=41.1078717201166, Blast_Score=241, Evalue=6e-64,
Organism=Homo sapiens, GI56118217, Length=343, Percent_Identity=41.1078717201166, Blast_Score=241, Evalue=6e-64,
Organism=Homo sapiens, GI189083684, Length=343, Percent_Identity=41.1078717201166, Blast_Score=241, Evalue=6e-64,
Organism=Homo sapiens, GI7657641, Length=320, Percent_Identity=25.9375, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI42516563, Length=308, Percent_Identity=23.7012987012987, Blast_Score=76, Evalue=5e-14,
Organism=Escherichia coli, GI1786974, Length=339, Percent_Identity=38.3480825958702, Blast_Score=230, Evalue=1e-61,
Organism=Escherichia coli, GI1788353, Length=356, Percent_Identity=28.9325842696629, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI48994969, Length=358, Percent_Identity=26.2569832402235, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1790049, Length=268, Percent_Identity=26.1194029850746, Blast_Score=66, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71982035, Length=345, Percent_Identity=37.1014492753623, Blast_Score=222, Evalue=2e-58,
Organism=Caenorhabditis elegans, GI71982038, Length=347, Percent_Identity=36.5994236311239, Blast_Score=221, Evalue=3e-58,
Organism=Caenorhabditis elegans, GI17539532, Length=315, Percent_Identity=24.4444444444444, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17568069, Length=271, Percent_Identity=27.6752767527675, Blast_Score=71, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6319493, Length=343, Percent_Identity=38.4839650145773, Blast_Score=218, Evalue=8e-58,
Organism=Drosophila melanogaster, GI19923002, Length=351, Percent_Identity=36.7521367521368, Blast_Score=225, Evalue=3e-59,
Organism=Drosophila melanogaster, GI21356223, Length=339, Percent_Identity=22.4188790560472, Blast_Score=72, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 35764; Mature: 35632

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSVLVTGGAGYIGSHTVLELTKQNRSVVVLDNLSTGHREAVSGVSFYEGDIADAALVKA
CCEEEEECCCCCCCCHHHEEEECCCCCEEEEECCCCCHHHHHCCCCCCCCCHHHHHHHHH
IIKHHDVDAVIHFAAKSLVSESIEKPEIYFRENTLKSCAFFETAIKEGVNNIVFSSTAAV
HHHHCCHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHEECCCHHE
YGIPEKAPIKEAAPLSPVNPYGESKLMIEKYLHWVGKTHGVKWAALRYFNAAGAALNGAI
EECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHCCCC
GEDHDPESHLIPLVLQTALGQRKQLSIFGEDYSTPDGTCIRDYIHVLDLASAHLAALDGL
CCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
YEDRLKQNVYNVGTGAGHSVKEIIETAENMTERSIAAKTDERRAGDPPVLVADSRTLVED
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCHHHHC
TGWKPQYSDLQTIIQSAWQWHKAHPDGF
CCCCCCHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TSVLVTGGAGYIGSHTVLELTKQNRSVVVLDNLSTGHREAVSGVSFYEGDIADAALVKA
CEEEEECCCCCCCCHHHEEEECCCCCEEEEECCCCCHHHHHCCCCCCCCCHHHHHHHHH
IIKHHDVDAVIHFAAKSLVSESIEKPEIYFRENTLKSCAFFETAIKEGVNNIVFSSTAAV
HHHHCCHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHEECCCHHE
YGIPEKAPIKEAAPLSPVNPYGESKLMIEKYLHWVGKTHGVKWAALRYFNAAGAALNGAI
EECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHCCCC
GEDHDPESHLIPLVLQTALGQRKQLSIFGEDYSTPDGTCIRDYIHVLDLASAHLAALDGL
CCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
YEDRLKQNVYNVGTGAGHSVKEIIETAENMTERSIAAKTDERRAGDPPVLVADSRTLVED
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCHHHHC
TGWKPQYSDLQTIIQSAWQWHKAHPDGF
CCCCCCHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]