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The map label for this gene is yfhQ [H]

Identifier: 52784683

GI number: 52784683

Start: 904149

End: 905234

Strand: Direct

Name: yfhQ [H]

Synonym: BLi00885

Alternate gene names: 52784683

Gene position: 904149-905234 (Clockwise)

Preceding gene: 52784681

Following gene: 52784685

Centisome position: 21.41

GC content: 46.96

Gene sequence:

>1086_bases
ATGATGGATCTGCAAAAGAAATTAGAGCAAAAAAACATCAAACAATTTCAAGAAGATTTAATTTCTTGGTATGAGCAAGA
AAAACGGGATCTGCCTTGGCGCTCAGACAGCGACCCTTATAAGGTGTGGGTGTCGGAAGTAATGCTTCAGCAGACGAGAG
TGGACACGGTGATTCCTTACTTCAACAACTTTATCGAAAAGTTTCCGACCGTGGAAGCGCTCGCTGAAGCCGACGAAGAA
AAAGTGCTTAAAGCCTGGGAAGGACTGGGATACTATTCAAGGGTTCGGAACTTGCAGAGCGCTGTCAGGGAAGTTCACGA
ACGATACGGGGGTGTGGTCCCTCCTTCAAAAGAGGAATTCGGCAGCTTAAAAGGCGTCGGCCCTTATACAAGAGGCGCGG
TGCTGAGCATCGCCTACAATCAGCCGGTCCCCGCGGTAGACGGAAATGTCATGCGGGTCATGTCACGGATTCTTTCCGTA
TGGGATGATATTGCAAAGCCTAAAACCAAAACCCTGTTTGAAAAAATTGTCGAAGCGTTTATTTCTGAGGAAAAACCGTC
CGAGTTTAACCAGGGGCTGATGGAGCTGGGCGCTGTCATCTGTACGCCGAAATCGCCATCATGCCTTCTCTGCCCGGTCC
GAGAGCACTGTTCTGCTTTTGCAGAAGGCTGTGAAAAAGAGCTTCCGGTTAAAAGCAAAAAGAAAAAACCTTCGGTAAAA
ACCCTTGCAGCTGTCGTCCTGACTGATGAAGAAGGATACATCTATATCCATAAAAGACCGGCATCAGGTCTTTTGGCAAA
CCTTTGGGAATTCCCAAACACAGAAACGCAGAAAGGCCTGAAGTACGAGCGCGAGCAGCTTGCGGCGTTTTTGAAAGAAG
AGGCCGGAATAGAAGCTGAAATCGGTCCGCTCGAAGGAGTCGTAGAGCATGTGTTTACACACCTTGTCTGGAACATTTCT
GTCTTTTTCGGGAAAACTCTCGATCAACCGGATGATTCATACTTTAAAAAGGTCACGAAAGAAGAGCTTGCTGAATACGC
CTTCCCGGTTTCGCATCAGAAAATATGGAATATGTATATGAAATAG

Upstream 100 bases:

>100_bases
ATGTAACATGTTATCGTATATGCATATAGTTTACAACAAAAAGCCGAAGTAACAAAAGATCGGTATGCAAATGTGACGTG
CACAGGCAAGGAGAAGTTTC

Downstream 100 bases:

>100_bases
GCAGCTTGACTGTGCATGCTGCCCGTTAGTCGTACTGGATGGTGGTGCCGTGCGTATAATCGGCTTCCTGGCGGCACAGT
CCGCCTCTTGCTTGAATTTC

Product: YfhQ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 361; Mature: 361

Protein sequence:

>361_residues
MMDLQKKLEQKNIKQFQEDLISWYEQEKRDLPWRSDSDPYKVWVSEVMLQQTRVDTVIPYFNNFIEKFPTVEALAEADEE
KVLKAWEGLGYYSRVRNLQSAVREVHERYGGVVPPSKEEFGSLKGVGPYTRGAVLSIAYNQPVPAVDGNVMRVMSRILSV
WDDIAKPKTKTLFEKIVEAFISEEKPSEFNQGLMELGAVICTPKSPSCLLCPVREHCSAFAEGCEKELPVKSKKKKPSVK
TLAAVVLTDEEGYIYIHKRPASGLLANLWEFPNTETQKGLKYEREQLAAFLKEEAGIEAEIGPLEGVVEHVFTHLVWNIS
VFFGKTLDQPDDSYFKKVTKEELAEYAFPVSHQKIWNMYMK

Sequences:

>Translated_361_residues
MMDLQKKLEQKNIKQFQEDLISWYEQEKRDLPWRSDSDPYKVWVSEVMLQQTRVDTVIPYFNNFIEKFPTVEALAEADEE
KVLKAWEGLGYYSRVRNLQSAVREVHERYGGVVPPSKEEFGSLKGVGPYTRGAVLSIAYNQPVPAVDGNVMRVMSRILSV
WDDIAKPKTKTLFEKIVEAFISEEKPSEFNQGLMELGAVICTPKSPSCLLCPVREHCSAFAEGCEKELPVKSKKKKPSVK
TLAAVVLTDEEGYIYIHKRPASGLLANLWEFPNTETQKGLKYEREQLAAFLKEEAGIEAEIGPLEGVVEHVFTHLVWNIS
VFFGKTLDQPDDSYFKKVTKEELAEYAFPVSHQKIWNMYMK
>Mature_361_residues
MMDLQKKLEQKNIKQFQEDLISWYEQEKRDLPWRSDSDPYKVWVSEVMLQQTRVDTVIPYFNNFIEKFPTVEALAEADEE
KVLKAWEGLGYYSRVRNLQSAVREVHERYGGVVPPSKEEFGSLKGVGPYTRGAVLSIAYNQPVPAVDGNVMRVMSRILSV
WDDIAKPKTKTLFEKIVEAFISEEKPSEFNQGLMELGAVICTPKSPSCLLCPVREHCSAFAEGCEKELPVKSKKKKPSVK
TLAAVVLTDEEGYIYIHKRPASGLLANLWEFPNTETQKGLKYEREQLAAFLKEEAGIEAEIGPLEGVVEHVFTHLVWNIS
VFFGKTLDQPDDSYFKKVTKEELAEYAFPVSHQKIWNMYMK

Specific function: Involved in the GO system responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine, 8- oxo-dGTP) from DNA and the nucleotide pool. 8-oxo-dGTP is inserted opposite dA and dC residues of template DNA with almost equal effici

COG id: COG1194

COG function: function code L; A/G-specific DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HhH domain [H]

Homologues:

Organism=Homo sapiens, GI115298650, Length=405, Percent_Identity=35.0617283950617, Blast_Score=219, Evalue=3e-57,
Organism=Homo sapiens, GI115298654, Length=405, Percent_Identity=35.0617283950617, Blast_Score=219, Evalue=3e-57,
Organism=Homo sapiens, GI115298652, Length=405, Percent_Identity=35.0617283950617, Blast_Score=219, Evalue=3e-57,
Organism=Homo sapiens, GI190358497, Length=405, Percent_Identity=35.0617283950617, Blast_Score=219, Evalue=3e-57,
Organism=Homo sapiens, GI115298648, Length=405, Percent_Identity=35.0617283950617, Blast_Score=219, Evalue=4e-57,
Organism=Homo sapiens, GI6912520, Length=405, Percent_Identity=35.0617283950617, Blast_Score=219, Evalue=4e-57,
Organism=Escherichia coli, GI1789331, Length=278, Percent_Identity=40.2877697841727, Blast_Score=205, Evalue=3e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011257
- InterPro:   IPR003651
- InterPro:   IPR003265
- InterPro:   IPR023170
- InterPro:   IPR005760
- InterPro:   IPR000086
- InterPro:   IPR015797 [H]

Pfam domain/function: PF00730 HhH-GPD [H]

EC number: 3.2.2.-

Molecular weight: Translated: 41315; Mature: 41315

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMDLQKKLEQKNIKQFQEDLISWYEQEKRDLPWRSDSDPYKVWVSEVMLQQTRVDTVIPY
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
FNNFIEKFPTVEALAEADEEKVLKAWEGLGYYSRVRNLQSAVREVHERYGGVVPPSKEEF
HHHHHHHCCHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
GSLKGVGPYTRGAVLSIAYNQPVPAVDGNVMRVMSRILSVWDDIAKPKTKTLFEKIVEAF
CCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
ISEEKPSEFNQGLMELGAVICTPKSPSCLLCPVREHCSAFAEGCEKELPVKSKKKKPSVK
HCCCCCCHHHHHHHHHHHEEECCCCCCEEECCHHHHHHHHHHHHHHCCCCCCCCCCCCHH
TLAAVVLTDEEGYIYIHKRPASGLLANLWEFPNTETQKGLKYEREQLAAFLKEEAGIEAE
HHHHHEEECCCCEEEEECCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCC
IGPLEGVVEHVFTHLVWNISVFFGKTLDQPDDSYFKKVTKEELAEYAFPVSHQKIWNMYM
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHC
K
C
>Mature Secondary Structure
MMDLQKKLEQKNIKQFQEDLISWYEQEKRDLPWRSDSDPYKVWVSEVMLQQTRVDTVIPY
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
FNNFIEKFPTVEALAEADEEKVLKAWEGLGYYSRVRNLQSAVREVHERYGGVVPPSKEEF
HHHHHHHCCHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
GSLKGVGPYTRGAVLSIAYNQPVPAVDGNVMRVMSRILSVWDDIAKPKTKTLFEKIVEAF
CCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
ISEEKPSEFNQGLMELGAVICTPKSPSCLLCPVREHCSAFAEGCEKELPVKSKKKKPSVK
HCCCCCCHHHHHHHHHHHEEECCCCCCEEECCHHHHHHHHHHHHHHCCCCCCCCCCCCHH
TLAAVVLTDEEGYIYIHKRPASGLLANLWEFPNTETQKGLKYEREQLAAFLKEEAGIEAE
HHHHHEEECCCCEEEEECCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCC
IGPLEGVVEHVFTHLVWNISVFFGKTLDQPDDSYFKKVTKEELAEYAFPVSHQKIWNMYM
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHC
K
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: 4Fe-4S Cluster [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Glycosylases; Hydrolysing N-glycosyl compounds [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8946165; 9384377 [H]