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The map label for this gene is yfmO [H]

Identifier: 52784573

GI number: 52784573

Start: 785247

End: 786431

Strand: Direct

Name: yfmO [H]

Synonym: BLi00774

Alternate gene names: 52784573

Gene position: 785247-786431 (Clockwise)

Preceding gene: 52784572

Following gene: 52784575

Centisome position: 18.6

GC content: 53.67

Gene sequence:

>1185_bases
ATGAATGAACAACCACCTGAGAACTCCAGTATGTTTAAACAGCCAAAAGCGGTCTGGGCGGTAGCCTTTGCCTGCGTGAT
CTCGTTTATGGGGATCGGGCTCGTCGATCCGATTCTGCCGGCGATCGCGCAGCAGCTGCATGCTTCCCCCAGCCAGGTTT
CGCTTTTATTTACAAGCTATCTGTTAGTCACAGGTTTTGCCATGCTTTTATCAGGCGCTGTCTCGAGCCGGATTGGAGCA
AAGCTGACGTTAATCAGCGGTTTGATCCTGATCATCGTCTTTGCGGGCCTGGGCGGGCTCTCGCATTCCATCTCTCAGCT
TGTCGGCTTCCGCGGCGGCTGGGGACTCGGAAACGCCATGTTTATCTCCACTGCGCTTGCCGTCATTGTCAGCGTGGCTT
CTGGCGGAAGCGCAAAAGCCATTATTTTGTATGAGGCTGCTTTGGGATTGGGCATTTCGGTTGGACCGCTTGCCGGCGGA
GAGCTTGGCACGATATCGTGGAGAGCGCCGTTTTTCGGTGTATCGGTTTTAATGGCCGCTGCTCTTTTGGCCATCTTTTT
TCTTTTGCCGCCTGTCCAAAAGCCGCAGAAGAAAATTTCCGTCAGTGCGCCGATCAAAGCGCTTCGTTATAAAGGGCTGT
TGACGCTGTCAGGAGCCGCATTCTTATATAATTTCGGTTTCTTCACCCTGCTTGCATATTCGCCGTTTGTTCTTGACTTA
AATGAACGGGGCCTCGGCTATGTCTTTTTCGGCTGGGGGCTGTTTCTTGCGATCACTTCCGTTTTTATCGCTCCGGCCGT
ACAGCGGATCTTCGGAACCGTCCGATCTCTGATCCTTCTGTTTATGCTGTTTGCAGCTGATTTGCTCGCGATCGGGATTT
GGACGGAGCACATGGCGCTCGTCATCGGGGCGATCATCATAGCCGGAGGTATTCTTGGCATGATCAATACGATTTTGACA
ACCGCGGTGATGGAAGCCGCGCCTGTCGAACGGTCTGTTGCTTCATCTGCCTACAGCTCCATCCGGTTCATCGGCGGGGC
CATTGCGCCTTGGATCGCCGGTGTGTTAGCCGATCATTTTACTGCGCATACTCCATATTTTGCAGGATGCATCGCCGTGC
TTGCCGGCATCGCCGTCTTGGCTGGAGGCCGCCGTTATTTGGCGGGCATCAAAGCCGGTCATTAA

Upstream 100 bases:

>100_bases
ATGCAGGCAAAAGCCGAGAATGCCCTACAATCAATTGATTAAACAAGACAAACGCTATTTTCATAGCGTTTCTTTATTTG
GAAAGAAGGTTTGATAGATA

Downstream 100 bases:

>100_bases
TGAAAAAAGCTTGTTTCCCTAAAAGGAAACAAGCTTTTTTGTTTATAAAACTTTCGTTGTCCATGACTCGCAATTCCATG
TTTCTGTCGCTATGTCCATA

Product: YfmO

Products: Proton [Cytoplasm]; multidrug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 394; Mature: 394

Protein sequence:

>394_residues
MNEQPPENSSMFKQPKAVWAVAFACVISFMGIGLVDPILPAIAQQLHASPSQVSLLFTSYLLVTGFAMLLSGAVSSRIGA
KLTLISGLILIIVFAGLGGLSHSISQLVGFRGGWGLGNAMFISTALAVIVSVASGGSAKAIILYEAALGLGISVGPLAGG
ELGTISWRAPFFGVSVLMAAALLAIFFLLPPVQKPQKKISVSAPIKALRYKGLLTLSGAAFLYNFGFFTLLAYSPFVLDL
NERGLGYVFFGWGLFLAITSVFIAPAVQRIFGTVRSLILLFMLFAADLLAIGIWTEHMALVIGAIIIAGGILGMINTILT
TAVMEAAPVERSVASSAYSSIRFIGGAIAPWIAGVLADHFTAHTPYFAGCIAVLAGIAVLAGGRRYLAGIKAGH

Sequences:

>Translated_394_residues
MNEQPPENSSMFKQPKAVWAVAFACVISFMGIGLVDPILPAIAQQLHASPSQVSLLFTSYLLVTGFAMLLSGAVSSRIGA
KLTLISGLILIIVFAGLGGLSHSISQLVGFRGGWGLGNAMFISTALAVIVSVASGGSAKAIILYEAALGLGISVGPLAGG
ELGTISWRAPFFGVSVLMAAALLAIFFLLPPVQKPQKKISVSAPIKALRYKGLLTLSGAAFLYNFGFFTLLAYSPFVLDL
NERGLGYVFFGWGLFLAITSVFIAPAVQRIFGTVRSLILLFMLFAADLLAIGIWTEHMALVIGAIIIAGGILGMINTILT
TAVMEAAPVERSVASSAYSSIRFIGGAIAPWIAGVLADHFTAHTPYFAGCIAVLAGIAVLAGGRRYLAGIKAGH
>Mature_394_residues
MNEQPPENSSMFKQPKAVWAVAFACVISFMGIGLVDPILPAIAQQLHASPSQVSLLFTSYLLVTGFAMLLSGAVSSRIGA
KLTLISGLILIIVFAGLGGLSHSISQLVGFRGGWGLGNAMFISTALAVIVSVASGGSAKAIILYEAALGLGISVGPLAGG
ELGTISWRAPFFGVSVLMAAALLAIFFLLPPVQKPQKKISVSAPIKALRYKGLLTLSGAAFLYNFGFFTLLAYSPFVLDL
NERGLGYVFFGWGLFLAITSVFIAPAVQRIFGTVRSLILLFMLFAADLLAIGIWTEHMALVIGAIIIAGGILGMINTILT
TAVMEAAPVERSVASSAYSSIRFIGGAIAPWIAGVLADHFTAHTPYFAGCIAVLAGIAVLAGGRRYLAGIKAGH

Specific function: Acts to efflux copper or a copper complex. It is possible that yfmO could contribute to copper resistance [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR001958 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 41037; Mature: 41037

Theoretical pI: Translated: 10.09; Mature: 10.09

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEQPPENSSMFKQPKAVWAVAFACVISFMGIGLVDPILPAIAQQLHASPSQVSLLFTSY
CCCCCCCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
LLVTGFAMLLSGAVSSRIGAKLTLISGLILIIVFAGLGGLSHSISQLVGFRGGWGLGNAM
HHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCHHH
FISTALAVIVSVASGGSAKAIILYEAALGLGISVGPLAGGELGTISWRAPFFGVSVLMAA
HHHHHHHHHHHHCCCCCCEEEEEEEHHHHCCCEECCCCCCCCCEEEECCHHHHHHHHHHH
ALLAIFFLLPPVQKPQKKISVSAPIKALRYKGLLTLSGAAFLYNFGFFTLLAYSPFVLDL
HHHHHHHHCCCCCCHHHHCCHHHHHHHHHHCCCCEECCHHHHHHHHHHHHHHCCCEEEEE
NERGLGYVFFGWGLFLAITSVFIAPAVQRIFGTVRSLILLFMLFAADLLAIGIWTEHMAL
CCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VIGAIIIAGGILGMINTILTTAVMEAAPVERSVASSAYSSIRFIGGAIAPWIAGVLADHF
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TAHTPYFAGCIAVLAGIAVLAGGRRYLAGIKAGH
HCCCCHHHHHHHHHHHHHHHHCCHHHHCCCCCCC
>Mature Secondary Structure
MNEQPPENSSMFKQPKAVWAVAFACVISFMGIGLVDPILPAIAQQLHASPSQVSLLFTSY
CCCCCCCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
LLVTGFAMLLSGAVSSRIGAKLTLISGLILIIVFAGLGGLSHSISQLVGFRGGWGLGNAM
HHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCHHH
FISTALAVIVSVASGGSAKAIILYEAALGLGISVGPLAGGELGTISWRAPFFGVSVLMAA
HHHHHHHHHHHHCCCCCCEEEEEEEHHHHCCCEECCCCCCCCCEEEECCHHHHHHHHHHH
ALLAIFFLLPPVQKPQKKISVSAPIKALRYKGLLTLSGAAFLYNFGFFTLLAYSPFVLDL
HHHHHHHHCCCCCCHHHHCCHHHHHHHHHHCCCCEECCHHHHHHHHHHHHHHCCCEEEEE
NERGLGYVFFGWGLFLAITSVFIAPAVQRIFGTVRSLILLFMLFAADLLAIGIWTEHMAL
CCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VIGAIIIAGGILGMINTILTTAVMEAAPVERSVASSAYSSIRFIGGAIAPWIAGVLADHF
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TAHTPYFAGCIAVLAGIAVLAGGRRYLAGIKAGH
HCCCCHHHHHHHHHHHHHHHHCCHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; multidrug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + multidrug [Cytoplasm] = Proton [Cytoplasm] + multidrug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9141694; 9384377 [H]