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The map label for this gene is iolF [H]

Identifier: 52784442

GI number: 52784442

Start: 641438

End: 642715

Strand: Reverse

Name: iolF [H]

Synonym: BLi00639

Alternate gene names: 52784442

Gene position: 642715-641438 (Counterclockwise)

Preceding gene: 52784448

Following gene: 52784440

Centisome position: 15.22

GC content: 52.82

Gene sequence:

>1278_bases
ATGCCAGGGAGAAAAAAAGGCAGTTTGAAGTCGACGATTACGGTCGCCATGTCCAACTATTTGGAGGCGGGATCCATCGT
CGCGGGGGCCGGCGGGCTTTCGTTATGGGTTGAATATTTAGGATTGGACGACGCCCGGGTCGGACTTCTCGGCGCCTTAA
GCGCAAATGGTTTCGGCGCGGCGATCGGCGCTTTTCTCGGCGGTTTTTTAGTCGACCGTTACGGGAGAAAATTCATATAT
AAATACGATCTATTAGTCTATATGCTTGGCGTTTTACTGATCGCCGCGTCGTTTAATTTTCCCATGCTTTTAACCGGATA
CATCGTGACGGGAATTGCGGTGGGCGCAGCAATTCCGGCTGCTTGGACTTACATTGCCGAGGAGGCCCCTGACCATGAAC
GGGCCGGACGCGTCGGCTGGGGGCAGCTGGCATGGTCGGTCGGACCGGCGCTTACGCTGCTGTTATCAGTTGCCTTGGCG
CCGCTCGGTTTAATGGGAAGCCGGTTGATTTTTGCCCAATTATTCGTCGTCGCAGTCATCACCTGGATTTTGCAGCAGCA
GATTCACGAATCGTCCATCTGGGAGGAGCAAAAGCGAAAAGAAGCCGAAGACAAAGCAAAAGGAGTTGAAGAAAAGGCGT
CGATCAAAGAGCTGTTGACCAACAAAGCGAACCTTCGCGCGATGATTCTCCTCATCGGAATTTATGCGTTTTGGAACCTT
GTTGCCGGGACGATGGGATATTTCATGCCGTATATCTATGAGACGGTCGGCGGCCTAACAGCGGCACAAGCCAACCTGCT
GCAGGCATTTTTATGGATTTTGACTGTGGCGTCCACATACTTCGTCTTTATCCGTCTCGGCGATAAAGTCAATCGGAAGT
TGCTTTTTGGCATAGGAGCAGCTATGGCAACCGCCGCATGGGTCATCCTCACCTTCGGCACGATGAACATCACGGAGCTT
TTATTATTCGTATGCCTGTGGGGCATTTCTGCGGGTTTTGGAGCGCAGGCGTTTTACGGACTGTGGGCGGCAGAGCTGTT
TCATACGAAATACAGGGCGCTCGCTCAAGGCTTCATGTTCTTCATCGTCCGCATCGGCGTCGGACTCATCTCATTGGTCG
TTCCGGCGATGATTACGGGCTTGGGCTTCAAAACAGCCGGCGCCGTCATGATTGCATTTCTCGTCATTCATATGATCATC
GGGCTCCGTATGGCGCCGGAAACGCGCGGCAAATCGCTTGAAGCCATTCAAAGCGAACGCTATCATCAAAGCGGCTGA

Upstream 100 bases:

>100_bases
GCTTACAATTTTGCATGACTCGCTAGGGTAAAATCGAGCATTCAACGCATCAATCCGGCTTCTGTCAGAAAAGAATTCTG
ATTTGAAAGGGGAACGAATC

Downstream 100 bases:

>100_bases
CCACACAGGTCAGGCCCGCTTGTTCTAAATCTGCGGGTTCGGGGCTGTCAACATCTTTCTCTTATCTGAATAAGGATCGC
TTTCAACTGCGACCTCTTGA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 425; Mature: 424

Protein sequence:

>425_residues
MPGRKKGSLKSTITVAMSNYLEAGSIVAGAGGLSLWVEYLGLDDARVGLLGALSANGFGAAIGAFLGGFLVDRYGRKFIY
KYDLLVYMLGVLLIAASFNFPMLLTGYIVTGIAVGAAIPAAWTYIAEEAPDHERAGRVGWGQLAWSVGPALTLLLSVALA
PLGLMGSRLIFAQLFVVAVITWILQQQIHESSIWEEQKRKEAEDKAKGVEEKASIKELLTNKANLRAMILLIGIYAFWNL
VAGTMGYFMPYIYETVGGLTAAQANLLQAFLWILTVASTYFVFIRLGDKVNRKLLFGIGAAMATAAWVILTFGTMNITEL
LLFVCLWGISAGFGAQAFYGLWAAELFHTKYRALAQGFMFFIVRIGVGLISLVVPAMITGLGFKTAGAVMIAFLVIHMII
GLRMAPETRGKSLEAIQSERYHQSG

Sequences:

>Translated_425_residues
MPGRKKGSLKSTITVAMSNYLEAGSIVAGAGGLSLWVEYLGLDDARVGLLGALSANGFGAAIGAFLGGFLVDRYGRKFIY
KYDLLVYMLGVLLIAASFNFPMLLTGYIVTGIAVGAAIPAAWTYIAEEAPDHERAGRVGWGQLAWSVGPALTLLLSVALA
PLGLMGSRLIFAQLFVVAVITWILQQQIHESSIWEEQKRKEAEDKAKGVEEKASIKELLTNKANLRAMILLIGIYAFWNL
VAGTMGYFMPYIYETVGGLTAAQANLLQAFLWILTVASTYFVFIRLGDKVNRKLLFGIGAAMATAAWVILTFGTMNITEL
LLFVCLWGISAGFGAQAFYGLWAAELFHTKYRALAQGFMFFIVRIGVGLISLVVPAMITGLGFKTAGAVMIAFLVIHMII
GLRMAPETRGKSLEAIQSERYHQSG
>Mature_424_residues
PGRKKGSLKSTITVAMSNYLEAGSIVAGAGGLSLWVEYLGLDDARVGLLGALSANGFGAAIGAFLGGFLVDRYGRKFIYK
YDLLVYMLGVLLIAASFNFPMLLTGYIVTGIAVGAAIPAAWTYIAEEAPDHERAGRVGWGQLAWSVGPALTLLLSVALAP
LGLMGSRLIFAQLFVVAVITWILQQQIHESSIWEEQKRKEAEDKAKGVEEKASIKELLTNKANLRAMILLIGIYAFWNLV
AGTMGYFMPYIYETVGGLTAAQANLLQAFLWILTVASTYFVFIRLGDKVNRKLLFGIGAAMATAAWVILTFGTMNITELL
LFVCLWGISAGFGAQAFYGLWAAELFHTKYRALAQGFMFFIVRIGVGLISLVVPAMITGLGFKTAGAVMIAFLVIHMIIG
LRMAPETRGKSLEAIQSERYHQSG

Specific function: Minor myo-inositol uptake transporter [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Escherichia coli, GI1786229, Length=399, Percent_Identity=25.31328320802, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1789207, Length=302, Percent_Identity=25.8278145695364, Blast_Score=64, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6323653, Length=440, Percent_Identity=25.4545454545455, Blast_Score=63, Evalue=8e-11,
Organism=Drosophila melanogaster, GI17737451, Length=421, Percent_Identity=26.1282660332542, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24652312, Length=421, Percent_Identity=26.1282660332542, Blast_Score=75, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46011; Mature: 45880

Theoretical pI: Translated: 9.63; Mature: 9.63

Prosite motif: PS50850 MFS ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HCCCC
>Mature Secondary Structure 
PGRKKGSLKSTITVAMSNYLEAGSIVAGAGGLSLWVEYLGLDDARVGLLGALSANGFGA
CCCCCCCHHHHHHHHHHHHHHCCCEEECCCHHHHHHHHHCCCCHHHHHHHHCCCCCHHH
AIGAFLGGFLVDRYGRKFIYKYDLLVYMLGVLLIAASFNFPMLLTGYIVTGIAVGAAIPA
HHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
AWTYIAEEAPDHERAGRVGWGQLAWSVGPALTLLLSVALAPLGLMGSRLIFAQLFVVAVI
HHHHHHHCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TWILQQQIHESSIWEEQKRKEAEDKAKGVEEKASIKELLTNKANLRAMILLIGIYAFWNL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
VAGTMGYFMPYIYETVGGLTAAQANLLQAFLWILTVASTYFVFIRLGDKVNRKLLFGIGA
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHEEECCHHCHHHHHHHHH
AMATAAWVILTFGTMNITELLLFVCLWGISAGFGAQAFYGLWAAELFHTKYRALAQGFMF
HHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
FIVRIGVGLISLVVPAMITGLGFKTAGAVMIAFLVIHMIIGLRMAPETRGKSLEAIQSER
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
YHQSG
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7952181; 9384377; 1761221; 11807058 [H]