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The map label for this gene is blaR1 [H]

Identifier: 52784101

GI number: 52784101

Start: 251407

End: 253206

Strand: Reverse

Name: blaR1 [H]

Synonym: BLi00278

Alternate gene names: 52784101

Gene position: 253206-251407 (Counterclockwise)

Preceding gene: 52784102

Following gene: 52784100

Centisome position: 6.0

GC content: 39.78

Gene sequence:

>1800_bases
ATGAGCAGTTCTTTCTTTATTCCCTTTTTGGTTAGTCAAATTCTATTGTCTCTGTTTTTTTCTCTCATCATACTCATAAA
AAAACTGCTGAAGGCTCAAATCACTGTAGGCACCCACTATCATCTTAGCGTGATTTCTCTTTTGGCATTGATCGCTCCTT
TTCTCCCCTTTCATTATCTAAAAAGCAATCATTTTGACTGGATTCTGAATTTAGGAGGAGCTAGCTCAACGCTATCTCAC
ACCCGTTCCACAGATAAGACGGCGGAAGCAATTGGCCAACATGCAAACTGGGTGCAGGATTTTTCGATGTCGATTGAACA
ATCGTCCTTCAAAATGATAGATTCAGCCTTTTTCGCAGTCTGGATATTGGGCATTGCTGTTATGCTTATCGCTACTCTTT
ATAGCAATCGAAAAATCGGCAAAATAAAAAAGAGCCTGCAAATGGTTAACAACAAAGAGCTATTAACCCTTTTTCGTACA
TGTAAAGAGGAAATACGCTTTCATCAAAAAGTGATTTTAGGCTGTTCCCCATTGATAAAATCCCCCATAACATTTGGGGT
TGTCCGTCCATATATTATCTTGCCAAAGGATATTTCAATGTTTTCTGCCGACGAGATGAAATGTGTTTTGCTTCATGAAC
TGTACCATTGTAAACGAAAAGATATGCTCATCAACTATTTTCTTTGCCTGTCCAAAATCGTCTATTGGTTTAATCCTCTC
GTGTGGTATTTATCAAAGGAAGCAAAAACAGAGATGGAGATTTCTTGCGACTTTGCCGTATTAAAAACGCTTGATAAAAA
ATTGCATCTCAAATATGGCGAGGTGATTTTAAAATTCACTTCACTTAAGCAAAGAACGTCATCTTTGGTAGCCGCTTCTG
AATTCAGCAGCTCATACAAACATATCAAAAGGCGGATTGTCACAGTTGTCAACTTCAAGGCGGCATCACCTTTGCTAAAG
GTGAAAAGCGCCTTAGTGTTCGCCCTTGTTCTTGGGATCATTCTAGCCGGCACTCCTTCTGTATCTATATTGACTATGCA
AAGAGATACGCACTTTTTATCTGGTGCAAATGTAGAATACGAAGATGACAGCACCTTTTTTGATGGCTTCTCAGGAGGTT
TTGTCCTGTTTGATTCTAACAGGAAAAAGTATACAATATACAATAGGAAAGAAAGCACCGCCAGATTCGCACCTGCTTCT
ACATACAAGGTGTTCAGCGCATTGCTCGCACTGGAATCCGGGATCATCACGAAGAACAATTCTCAAATGACGTGGGACGG
AACTCAATATCCGTATAAAGAATGGAATCAAGACCAGGATTTATTCTCTGCGATGAGCAGCTCCGCAACATGGTATTTTC
AAAAACTGGACCGGCAAATTGGAGAGGATCATTTGCGTCGCTATCTCAAATCTATCCATTATGGAAATGAGGATTTCTCA
GGTCCGGCGAATTATTGGCTGGATGGCTCTCTTCAAATTTCCCCTCTTGAACAGGTTAATATGTTAAAAAAGTTTTATGA
TAACGAATTTGATTTTAAACAGTCTAATATTCAAACTGTGAAAGATTCGATACGTTTAGAAGAATCAAATGGCAGAATTC
TATCCGGTAAAACCGGGACTTCAGTTATCAACGGAGAACTTCATGCCGGCTGGTTTGTCGGATATGTAGAAACTGCCGAA
AATACTTTTTTCTTTGCTGTTCATATTCAAGGTGAAAAACGGGCTGCCGGAAGCACTGCTGCCGAGATTGCACTTTCCAT
CTTGGATAAAAAAGGGATTTATCCATCCGCTTCCCGATAA

Upstream 100 bases:

>100_bases
ATGGTATTAAACTTTTTGGAGAATGATCAGCTGTCAGGTGAAGAAATTAATGAGTTGTATCAAATACTAGAAGAACATAA
GAACAGAAAGAAGGAATGAA

Downstream 100 bases:

>100_bases
CAGTTTTGCATTTTATCCTATGAACATGAATAATGCGCAGATAGATGAATGGTTCTTTCACCTTCCTAAATAAAACGGAA
CTTGGAGGCAAGATCATGGA

Product: regulatory protein blaR1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 599; Mature: 598

Protein sequence:

>599_residues
MSSSFFIPFLVSQILLSLFFSLIILIKKLLKAQITVGTHYHLSVISLLALIAPFLPFHYLKSNHFDWILNLGGASSTLSH
TRSTDKTAEAIGQHANWVQDFSMSIEQSSFKMIDSAFFAVWILGIAVMLIATLYSNRKIGKIKKSLQMVNNKELLTLFRT
CKEEIRFHQKVILGCSPLIKSPITFGVVRPYIILPKDISMFSADEMKCVLLHELYHCKRKDMLINYFLCLSKIVYWFNPL
VWYLSKEAKTEMEISCDFAVLKTLDKKLHLKYGEVILKFTSLKQRTSSLVAASEFSSSYKHIKRRIVTVVNFKAASPLLK
VKSALVFALVLGIILAGTPSVSILTMQRDTHFLSGANVEYEDDSTFFDGFSGGFVLFDSNRKKYTIYNRKESTARFAPAS
TYKVFSALLALESGIITKNNSQMTWDGTQYPYKEWNQDQDLFSAMSSSATWYFQKLDRQIGEDHLRRYLKSIHYGNEDFS
GPANYWLDGSLQISPLEQVNMLKKFYDNEFDFKQSNIQTVKDSIRLEESNGRILSGKTGTSVINGELHAGWFVGYVETAE
NTFFFAVHIQGEKRAAGSTAAEIALSILDKKGIYPSASR

Sequences:

>Translated_599_residues
MSSSFFIPFLVSQILLSLFFSLIILIKKLLKAQITVGTHYHLSVISLLALIAPFLPFHYLKSNHFDWILNLGGASSTLSH
TRSTDKTAEAIGQHANWVQDFSMSIEQSSFKMIDSAFFAVWILGIAVMLIATLYSNRKIGKIKKSLQMVNNKELLTLFRT
CKEEIRFHQKVILGCSPLIKSPITFGVVRPYIILPKDISMFSADEMKCVLLHELYHCKRKDMLINYFLCLSKIVYWFNPL
VWYLSKEAKTEMEISCDFAVLKTLDKKLHLKYGEVILKFTSLKQRTSSLVAASEFSSSYKHIKRRIVTVVNFKAASPLLK
VKSALVFALVLGIILAGTPSVSILTMQRDTHFLSGANVEYEDDSTFFDGFSGGFVLFDSNRKKYTIYNRKESTARFAPAS
TYKVFSALLALESGIITKNNSQMTWDGTQYPYKEWNQDQDLFSAMSSSATWYFQKLDRQIGEDHLRRYLKSIHYGNEDFS
GPANYWLDGSLQISPLEQVNMLKKFYDNEFDFKQSNIQTVKDSIRLEESNGRILSGKTGTSVINGELHAGWFVGYVETAE
NTFFFAVHIQGEKRAAGSTAAEIALSILDKKGIYPSASR
>Mature_598_residues
SSSFFIPFLVSQILLSLFFSLIILIKKLLKAQITVGTHYHLSVISLLALIAPFLPFHYLKSNHFDWILNLGGASSTLSHT
RSTDKTAEAIGQHANWVQDFSMSIEQSSFKMIDSAFFAVWILGIAVMLIATLYSNRKIGKIKKSLQMVNNKELLTLFRTC
KEEIRFHQKVILGCSPLIKSPITFGVVRPYIILPKDISMFSADEMKCVLLHELYHCKRKDMLINYFLCLSKIVYWFNPLV
WYLSKEAKTEMEISCDFAVLKTLDKKLHLKYGEVILKFTSLKQRTSSLVAASEFSSSYKHIKRRIVTVVNFKAASPLLKV
KSALVFALVLGIILAGTPSVSILTMQRDTHFLSGANVEYEDDSTFFDGFSGGFVLFDSNRKKYTIYNRKESTARFAPAST
YKVFSALLALESGIITKNNSQMTWDGTQYPYKEWNQDQDLFSAMSSSATWYFQKLDRQIGEDHLRRYLKSIHYGNEDFSG
PANYWLDGSLQISPLEQVNMLKKFYDNEFDFKQSNIQTVKDSIRLEESNGRILSGKTGTSVINGELHAGWFVGYVETAEN
TFFFAVHIQGEKRAAGSTAAEIALSILDKKGIYPSASR

Specific function: BlaR1 is a potential penicillin-binding protein required for induction of beta-lactamase in Bacillus licheniformis [H]

COG id: COG2602

COG function: function code V; Beta-lactamase class D

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M56 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001460
- InterPro:   IPR008756 [H]

Pfam domain/function: PF05569 Peptidase_M56; PF00905 Transpeptidase [H]

EC number: NA

Molecular weight: Translated: 67963; Mature: 67832

Theoretical pI: Translated: 9.61; Mature: 9.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSSFFIPFLVSQILLSLFFSLIILIKKLLKAQITVGTHYHLSVISLLALIAPFLPFHYL
CCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
KSNHFDWILNLGGASSTLSHTRSTDKTAEAIGQHANWVQDFSMSIEQSSFKMIDSAFFAV
CCCCCEEEEECCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WILGIAVMLIATLYSNRKIGKIKKSLQMVNNKELLTLFRTCKEEIRFHQKVILGCSPLIK
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
SPITFGVVRPYIILPKDISMFSADEMKCVLLHELYHCKRKDMLINYFLCLSKIVYWFNPL
CCCHHHCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VWYLSKEAKTEMEISCDFAVLKTLDKKLHLKYGEVILKFTSLKQRTSSLVAASEFSSSYK
HHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HIKRRIVTVVNFKAASPLLKVKSALVFALVLGIILAGTPSVSILTMQRDTHFLSGANVEY
HHHHHHHHHEECHHCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCEECCCCCEE
EDDSTFFDGFSGGFVLFDSNRKKYTIYNRKESTARFAPASTYKVFSALLALESGIITKNN
CCCCCEECCCCCCEEEEECCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCEECCC
SQMTWDGTQYPYKEWNQDQDLFSAMSSSATWYFQKLDRQIGEDHLRRYLKSIHYGNEDFS
CEEEECCCCCCHHHCCCCHHHHHHHHCCCHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCC
GPANYWLDGSLQISPLEQVNMLKKFYDNEFDFKQSNIQTVKDSIRLEESNGRILSGKTGT
CCCCCEECCCEEECCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHEEECCCCEEEECCCCC
SVINGELHAGWFVGYVETAENTFFFAVHIQGEKRAAGSTAAEIALSILDKKGIYPSASR
EEECCCEECCEEEEEEEECCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SSSFFIPFLVSQILLSLFFSLIILIKKLLKAQITVGTHYHLSVISLLALIAPFLPFHYL
CCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
KSNHFDWILNLGGASSTLSHTRSTDKTAEAIGQHANWVQDFSMSIEQSSFKMIDSAFFAV
CCCCCEEEEECCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WILGIAVMLIATLYSNRKIGKIKKSLQMVNNKELLTLFRTCKEEIRFHQKVILGCSPLIK
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
SPITFGVVRPYIILPKDISMFSADEMKCVLLHELYHCKRKDMLINYFLCLSKIVYWFNPL
CCCHHHCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VWYLSKEAKTEMEISCDFAVLKTLDKKLHLKYGEVILKFTSLKQRTSSLVAASEFSSSYK
HHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HIKRRIVTVVNFKAASPLLKVKSALVFALVLGIILAGTPSVSILTMQRDTHFLSGANVEY
HHHHHHHHHEECHHCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCEECCCCCEE
EDDSTFFDGFSGGFVLFDSNRKKYTIYNRKESTARFAPASTYKVFSALLALESGIITKNN
CCCCCEECCCCCCEEEEECCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCEECCC
SQMTWDGTQYPYKEWNQDQDLFSAMSSSATWYFQKLDRQIGEDHLRRYLKSIHYGNEDFS
CEEEECCCCCCHHHCCCCHHHHHHHHCCCHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCC
GPANYWLDGSLQISPLEQVNMLKKFYDNEFDFKQSNIQTVKDSIRLEESNGRILSGKTGT
CCCCCEECCCEEECCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHEEECCCCEEEECCCCC
SVINGELHAGWFVGYVETAENTFFFAVHIQGEKRAAGSTAAEIALSILDKKGIYPSASR
EEECCCEECCEEEEEEEECCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3040663; 3260234; 2404938 [H]