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The map label for this gene is citM [H]

Identifier: 52784048

GI number: 52784048

Start: 198676

End: 199974

Strand: Reverse

Name: citM [H]

Synonym: BLi00221

Alternate gene names: 52784048

Gene position: 199974-198676 (Counterclockwise)

Preceding gene: 52784049

Following gene: 52784040

Centisome position: 4.74

GC content: 47.96

Gene sequence:

>1299_bases
GTGTTAGCAATTTTAGGTTTTTTCATGATGCTTGTGTTTATGGTATTGATCATGACAAAACGGCTTTCTGTTCTGACGGC
ATTAGTCTTGACACCGATAGTGTTTGCGCTGATCGCCGGATTCGGATTCAGCGATGTCGGCGACATGATGATTTCGGGGA
TTCAGCAAGTCGCGCCAACCGCCGTTATGATTATGTTTGCAATTTTATATTTCGGGATTATGATTGATACTGGCCTGTTT
GACCCAATGGTCACAAAAATATTAAAAATGGTCAAAGGCGATCCGTTAAAAATCGTCGTCGGCACTGCGGTGCTCACGAT
GCTGGTCGCATTGGACGGAGACGGATCAACAACATATATGATTACAACGAGCGCGATGCTCCCGCTCTATTTGCTGCTTG
GCATCCGCCCGATTATATTAGCGGGAATCGCAGGAGTCGGCATGGGGATTATGAATACGATTCCATGGGGAGGCGCAACA
CCGCGGGCAGCGAGTGCGCTCGGGGTTGACCCGGCTGAATTGACCGGCCCGATGATACCTGTCATCGTAAGCGGCATGCT
TTGTATGATCGGAGTTGCGTATATGCTCGGAAAAGCGGAGCGAAAACGCCTCGGCGTGATTGAACTCAAACATCCGGCTG
GTGCCAATGAAACGGCCGCCGCTGCGGAGGATGAGTGGAAGCGTCCGAAGCTTTGGTGGTTCAACTTATTGTTGACGCTT
TCATTGATAGGGCTTCTCATATCAGGAAAAGTAAGCTTGACCGTTCTGTTTATTATCGCGTTCTGCATCGCATTGATTGT
CAATTATCCAAACCTCGATCATCAGAGACAGCGAATTTCGGCGCATTCGAGCAATGTATTGGCTATCGGTTCAATGATAT
TTGCCGCAGGGGTCTTTACCGGAATACTAACAGGCACAAAAATGGTAGATGAAATGGCGATTTCGCTTGCGTCTATGATT
CCTGAACAAATGGGCGGCTTTATTCCGATGATAGTAGCCTTAACAAGCGGCATTTTCACTTTTCTGATGCCGAATGACGC
TTATTTTTACGGAGTGCTCCCGATTTTATCAGAAACCGCTGTCGCATACGGTGTTAATAAGGTCGAAATTGCAAGAGCCT
CCATCATCGGCCAGCCGATTCACATGCTGAGCCCGCTTGTGCCTTCAACACATTTGCTTGTTGGGCTTGTCGGGGTTTCC
ATCGACGATCATCAAAAATTTGCGATAATGTGGGCGGTGCTCGCTGTCATCGTGATGACAGGATGCGCGCTTCTCATCGG
ATCCATATCAATTTATTGA

Upstream 100 bases:

>100_bases
TACTTCAGAAAGTTCTTCTCATATGATGACAAAAAGGCAAGGCTTAGGGGGAACAGGAGAGAAAAAAATGTAAGCGGATT
CATATGAGGGGGGAATAACT

Downstream 100 bases:

>100_bases
TGGTGTTGATCGCTTCAATGCCCTTATGAGGGCGATACACGTATCGCAGCATACCTTTTCACATAGCGGCCTTTTTAAGC
TTGCAGAGACACTCCTGTTT

Product: CitM

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 432; Mature: 432

Protein sequence:

>432_residues
MLAILGFFMMLVFMVLIMTKRLSVLTALVLTPIVFALIAGFGFSDVGDMMISGIQQVAPTAVMIMFAILYFGIMIDTGLF
DPMVTKILKMVKGDPLKIVVGTAVLTMLVALDGDGSTTYMITTSAMLPLYLLLGIRPIILAGIAGVGMGIMNTIPWGGAT
PRAASALGVDPAELTGPMIPVIVSGMLCMIGVAYMLGKAERKRLGVIELKHPAGANETAAAAEDEWKRPKLWWFNLLLTL
SLIGLLISGKVSLTVLFIIAFCIALIVNYPNLDHQRQRISAHSSNVLAIGSMIFAAGVFTGILTGTKMVDEMAISLASMI
PEQMGGFIPMIVALTSGIFTFLMPNDAYFYGVLPILSETAVAYGVNKVEIARASIIGQPIHMLSPLVPSTHLLVGLVGVS
IDDHQKFAIMWAVLAVIVMTGCALLIGSISIY

Sequences:

>Translated_432_residues
MLAILGFFMMLVFMVLIMTKRLSVLTALVLTPIVFALIAGFGFSDVGDMMISGIQQVAPTAVMIMFAILYFGIMIDTGLF
DPMVTKILKMVKGDPLKIVVGTAVLTMLVALDGDGSTTYMITTSAMLPLYLLLGIRPIILAGIAGVGMGIMNTIPWGGAT
PRAASALGVDPAELTGPMIPVIVSGMLCMIGVAYMLGKAERKRLGVIELKHPAGANETAAAAEDEWKRPKLWWFNLLLTL
SLIGLLISGKVSLTVLFIIAFCIALIVNYPNLDHQRQRISAHSSNVLAIGSMIFAAGVFTGILTGTKMVDEMAISLASMI
PEQMGGFIPMIVALTSGIFTFLMPNDAYFYGVLPILSETAVAYGVNKVEIARASIIGQPIHMLSPLVPSTHLLVGLVGVS
IDDHQKFAIMWAVLAVIVMTGCALLIGSISIY
>Mature_432_residues
MLAILGFFMMLVFMVLIMTKRLSVLTALVLTPIVFALIAGFGFSDVGDMMISGIQQVAPTAVMIMFAILYFGIMIDTGLF
DPMVTKILKMVKGDPLKIVVGTAVLTMLVALDGDGSTTYMITTSAMLPLYLLLGIRPIILAGIAGVGMGIMNTIPWGGAT
PRAASALGVDPAELTGPMIPVIVSGMLCMIGVAYMLGKAERKRLGVIELKHPAGANETAAAAEDEWKRPKLWWFNLLLTL
SLIGLLISGKVSLTVLFIIAFCIALIVNYPNLDHQRQRISAHSSNVLAIGSMIFAAGVFTGILTGTKMVDEMAISLASMI
PEQMGGFIPMIVALTSGIFTFLMPNDAYFYGVLPILSETAVAYGVNKVEIARASIIGQPIHMLSPLVPSTHLLVGLVGVS
IDDHQKFAIMWAVLAVIVMTGCALLIGSISIY

Specific function: Proton motive force-driven secondary transporter that mediates the transport of citrate complexed to Mg(2+). Cotransports at least two protons per Mg(2+)-citrate complex. Can also transport citrate in complex with Ni(2+), Mn(2+), Co(2+), and Zn(2+) [H]

COG id: COG2851

COG function: function code C; H+/citrate symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CitM (TC 2.A.11) transporter family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014738
- InterPro:   IPR004680 [H]

Pfam domain/function: PF03600 CitMHS [H]

EC number: NA

Molecular weight: Translated: 46016; Mature: 46016

Theoretical pI: Translated: 7.12; Mature: 7.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
7.2 %Met     (Translated Protein)
7.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
7.2 %Met     (Mature Protein)
7.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAILGFFMMLVFMVLIMTKRLSVLTALVLTPIVFALIAGFGFSDVGDMMISGIQQVAPT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
AVMIMFAILYFGIMIDTGLFDPMVTKILKMVKGDPLKIVVGTAVLTMLVALDGDGSTTYM
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCEEHHHHHHHHHHHHCCCCCCEEEE
ITTSAMLPLYLLLGIRPIILAGIAGVGMGIMNTIPWGGATPRAASALGVDPAELTGPMIP
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCHHHHCCCHHH
VIVSGMLCMIGVAYMLGKAERKRLGVIELKHPAGANETAAAAEDEWKRPKLWWFNLLLTL
HHHHHHHHHHHHHHHHCHHHHHHCCEEEEECCCCCCCCHHCCHHHCCCCHHHHHHHHHHH
SLIGLLISGKVSLTVLFIIAFCIALIVNYPNLDHQRQRISAHSSNVLAIGSMIFAAGVFT
HHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHH
GILTGTKMVDEMAISLASMIPEQMGGFIPMIVALTSGIFTFLMPNDAYFYGVLPILSETA
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHH
VAYGVNKVEIARASIIGQPIHMLSPLVPSTHLLVGLVGVSIDDHQKFAIMWAVLAVIVMT
HHHCCCHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
GCALLIGSISIY
HHHHHHHHHCCC
>Mature Secondary Structure
MLAILGFFMMLVFMVLIMTKRLSVLTALVLTPIVFALIAGFGFSDVGDMMISGIQQVAPT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
AVMIMFAILYFGIMIDTGLFDPMVTKILKMVKGDPLKIVVGTAVLTMLVALDGDGSTTYM
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCEEHHHHHHHHHHHHCCCCCCEEEE
ITTSAMLPLYLLLGIRPIILAGIAGVGMGIMNTIPWGGATPRAASALGVDPAELTGPMIP
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCHHHHCCCHHH
VIVSGMLCMIGVAYMLGKAERKRLGVIELKHPAGANETAAAAEDEWKRPKLWWFNLLLTL
HHHHHHHHHHHHHHHHCHHHHHHCCEEEEECCCCCCCCHHCCHHHCCCCHHHHHHHHHHH
SLIGLLISGKVSLTVLFIIAFCIALIVNYPNLDHQRQRISAHSSNVLAIGSMIFAAGVFT
HHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHH
GILTGTKMVDEMAISLASMIPEQMGGFIPMIVALTSGIFTFLMPNDAYFYGVLPILSETA
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHH
VAYGVNKVEIARASIIGQPIHMLSPLVPSTHLLVGLVGVSIDDHQKFAIMWAVLAVIVMT
HHHCCCHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
GCALLIGSISIY
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8892821; 9272861; 9384377; 11029430; 10972810; 11053381; 11891560 [H]