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The map label for this gene is yyxA [H]

Identifier: 52145269

GI number: 52145269

Start: 5273307

End: 5274482

Strand: Reverse

Name: yyxA [H]

Synonym: BCZK5158

Alternate gene names: 52145269

Gene position: 5274482-5273307 (Counterclockwise)

Preceding gene: 52145270

Following gene: 52145268

Centisome position: 99.5

GC content: 38.35

Gene sequence:

>1176_bases
ATGTCCTTTATTGATGGAGAAAATTATCGTATGAAACGTGCAAGGAAAAAGAAGCATAAAGGTATTGTTATTTCTAGTAT
AGCAGGAACAATTGTAGGGGCTTCGTTATTTGCATTTGGAGCTCCTTTATTTTCAAATGATGCGGACGCGTTTCCGCAAG
CTGAAGCAAGTGGAAGTAATATGGCCGAAGCTCAAGGAATTAAACAGATTAGCTTTGTGGATGCTGTTGATCGTGCGTCT
GAAGCTGTTGTTGGAGTTATTAATATTCAACGAGATAATTTTTCAGAGGCAGATTCAGAAGCAGGTACGGGATCAGGTGT
AATTTATAAGAAGACAGATGGTCAAGCTTATATTGTAACGAATAATCATGTCGTTGCTGGAGCAAATCGTATTGAAGTAA
GTTTAAGTGATGGTAAGAAGGTCCCTGGAAAGGTATTAGGAACCGATGTGGTCACAGATTTGGCTGTACTAGAGATAGAT
GCAAAGCATGTGAAAAAAGTAATTGAGATTGGTGATTCTAATACTGTTCGTAGAGGAGAACCAGTCATTGCGATTGGAAA
CCCGCTCGGGCTACAATTTTCTGGAACCGTCACACAAGGTATTATTTCGGCTAATGAGCGTATTGTTCCTGTAGATTTAG
ATCAAGATGGACATTATGATTGGCAAGTAGAAGTATTGCAAACAGACGCAGCAATTAATCCGGGTAATAGTGGTGGTGCG
CTTGTAAATGCAGCAGGTCAATTAATTGGTATTAACTCAATGAAAATTGCTGCAAAAGAAGTAGAAGGAATTGGTCTAGC
TATTCCAGTGACTAGAGCTGTTCCAATTATGAATGAATTAGAGAAGTATGGAAAAGTAAGAAGACCGTATGTTGGAATTG
AACTGAGATCATTAAATGAGATTCCAAACTACTATTGGTCAAAAACATTGCATTTACCAGGCAATGTAACAGAGGGAGTT
TGCATTTTAGATGTGAAAAGTCCTTCGCCAGGCACAGATGCTGGTTTACGAGAACACGATGTAATTGTAGCAGTAGATGG
AAAACCGGTTCGTGATATTATCGGATTCCGTACGGCCTTATATGATAAAAAAATTAATGATAAAATGACTCTTACGTTTT
ATCGTGGTACAAAACGAGCAACAACAACGGTTAAACTAGGCATTCAAAAGTATTAA

Upstream 100 bases:

>100_bases
AGATCCAAAAATGCCTACAAAAATTCAATACGTATAATTCTCCATTTTAGTAAACAATAAAGGTGAATATAGTTGTTTTC
AGGAAGATAGGTGAACAAAT

Downstream 100 bases:

>100_bases
AAACAGGAGGGCCTACCTCCTGTTTTCTATTGTAGAAAAGTGAGGTGAAGAATATGAATTTACCTTGTTGTTTAGAACAT
GTTGAATTAGCGTTAGATAT

Product: serine protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 391; Mature: 390

Protein sequence:

>391_residues
MSFIDGENYRMKRARKKKHKGIVISSIAGTIVGASLFAFGAPLFSNDADAFPQAEASGSNMAEAQGIKQISFVDAVDRAS
EAVVGVINIQRDNFSEADSEAGTGSGVIYKKTDGQAYIVTNNHVVAGANRIEVSLSDGKKVPGKVLGTDVVTDLAVLEID
AKHVKKVIEIGDSNTVRRGEPVIAIGNPLGLQFSGTVTQGIISANERIVPVDLDQDGHYDWQVEVLQTDAAINPGNSGGA
LVNAAGQLIGINSMKIAAKEVEGIGLAIPVTRAVPIMNELEKYGKVRRPYVGIELRSLNEIPNYYWSKTLHLPGNVTEGV
CILDVKSPSPGTDAGLREHDVIVAVDGKPVRDIIGFRTALYDKKINDKMTLTFYRGTKRATTTVKLGIQKY

Sequences:

>Translated_391_residues
MSFIDGENYRMKRARKKKHKGIVISSIAGTIVGASLFAFGAPLFSNDADAFPQAEASGSNMAEAQGIKQISFVDAVDRAS
EAVVGVINIQRDNFSEADSEAGTGSGVIYKKTDGQAYIVTNNHVVAGANRIEVSLSDGKKVPGKVLGTDVVTDLAVLEID
AKHVKKVIEIGDSNTVRRGEPVIAIGNPLGLQFSGTVTQGIISANERIVPVDLDQDGHYDWQVEVLQTDAAINPGNSGGA
LVNAAGQLIGINSMKIAAKEVEGIGLAIPVTRAVPIMNELEKYGKVRRPYVGIELRSLNEIPNYYWSKTLHLPGNVTEGV
CILDVKSPSPGTDAGLREHDVIVAVDGKPVRDIIGFRTALYDKKINDKMTLTFYRGTKRATTTVKLGIQKY
>Mature_390_residues
SFIDGENYRMKRARKKKHKGIVISSIAGTIVGASLFAFGAPLFSNDADAFPQAEASGSNMAEAQGIKQISFVDAVDRASE
AVVGVINIQRDNFSEADSEAGTGSGVIYKKTDGQAYIVTNNHVVAGANRIEVSLSDGKKVPGKVLGTDVVTDLAVLEIDA
KHVKKVIEIGDSNTVRRGEPVIAIGNPLGLQFSGTVTQGIISANERIVPVDLDQDGHYDWQVEVLQTDAAINPGNSGGAL
VNAAGQLIGINSMKIAAKEVEGIGLAIPVTRAVPIMNELEKYGKVRRPYVGIELRSLNEIPNYYWSKTLHLPGNVTEGVC
ILDVKSPSPGTDAGLREHDVIVAVDGKPVRDIIGFRTALYDKKINDKMTLTFYRGTKRATTTVKLGIQKY

Specific function: Unknown

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=284, Percent_Identity=34.5070422535211, Blast_Score=132, Evalue=5e-31,
Organism=Homo sapiens, GI24308541, Length=289, Percent_Identity=34.9480968858132, Blast_Score=127, Evalue=1e-29,
Organism=Homo sapiens, GI22129776, Length=288, Percent_Identity=31.9444444444444, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI7019477, Length=322, Percent_Identity=36.0248447204969, Blast_Score=123, Evalue=3e-28,
Organism=Escherichia coli, GI1789630, Length=378, Percent_Identity=35.978835978836, Blast_Score=161, Evalue=6e-41,
Organism=Escherichia coli, GI1786356, Length=284, Percent_Identity=36.9718309859155, Blast_Score=153, Evalue=2e-38,
Organism=Escherichia coli, GI1789629, Length=286, Percent_Identity=34.6153846153846, Blast_Score=142, Evalue=3e-35,
Organism=Drosophila melanogaster, GI24646839, Length=306, Percent_Identity=34.9673202614379, Blast_Score=137, Evalue=1e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 41874; Mature: 41743

Theoretical pI: Translated: 7.74; Mature: 7.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFIDGENYRMKRARKKKHKGIVISSIAGTIVGASLFAFGAPLFSNDADAFPQAEASGSN
CCCCCCCCHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
MAEAQGIKQISFVDAVDRASEAVVGVINIQRDNFSEADSEAGTGSGVIYKKTDGQAYIVT
CHHHHCCCEEHHHHHHHHCCCEEEEEEEEECCCCCCCCCCCCCCCCEEEEECCCCEEEEE
NNHVVAGANRIEVSLSDGKKVPGKVLGTDVVTDLAVLEIDAKHVKKVIEIGDSNTVRRGE
CCEEEECCCEEEEEECCCCCCCCHHCCHHHHHEEEEEEECHHHHHHHHHCCCCCCEECCC
PVIAIGNPLGLQFSGTVTQGIISANERIVPVDLDQDGHYDWQVEVLQTDAAINPGNSGGA
CEEEECCCCCEEECCCHHHHHCCCCCEEEEEECCCCCCCEEEEEEEEECCCCCCCCCCCE
LVNAAGQLIGINSMKIAAKEVEGIGLAIPVTRAVPIMNELEKYGKVRRPYVGIELRSLNE
EEECCCCEEECCCCEEEHHHHCCCEEEEEHHHHHHHHHHHHHHCCCCCCEEEEEECCHHC
IPNYYWSKTLHLPGNVTEGVCILDVKSPSPGTDAGLREHDVIVAVDGKPVRDIIGFRTAL
CCCCHHCEEEECCCCCCCCEEEEEECCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHH
YDKKINDKMTLTFYRGTKRATTTVKLGIQKY
HCCCCCCCEEEEEEECCCCEEEEEEEEEECC
>Mature Secondary Structure 
SFIDGENYRMKRARKKKHKGIVISSIAGTIVGASLFAFGAPLFSNDADAFPQAEASGSN
CCCCCCCHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
MAEAQGIKQISFVDAVDRASEAVVGVINIQRDNFSEADSEAGTGSGVIYKKTDGQAYIVT
CHHHHCCCEEHHHHHHHHCCCEEEEEEEEECCCCCCCCCCCCCCCCEEEEECCCCEEEEE
NNHVVAGANRIEVSLSDGKKVPGKVLGTDVVTDLAVLEIDAKHVKKVIEIGDSNTVRRGE
CCEEEECCCEEEEEECCCCCCCCHHCCHHHHHEEEEEEECHHHHHHHHHCCCCCCEECCC
PVIAIGNPLGLQFSGTVTQGIISANERIVPVDLDQDGHYDWQVEVLQTDAAINPGNSGGA
CEEEECCCCCEEECCCHHHHHCCCCCEEEEEECCCCCCCEEEEEEEEECCCCCCCCCCCE
LVNAAGQLIGINSMKIAAKEVEGIGLAIPVTRAVPIMNELEKYGKVRRPYVGIELRSLNE
EEECCCCEEECCCCEEEHHHHCCCEEEEEHHHHHHHHHHHHHHCCCCCCEEEEEECCHHC
IPNYYWSKTLHLPGNVTEGVCILDVKSPSPGTDAGLREHDVIVAVDGKPVRDIIGFRTAL
CCCCHHCEEEECCCCCCCCEEEEEECCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHH
YDKKINDKMTLTFYRGTKRATTTVKLGIQKY
HCCCCCCCEEEEEEECCCCEEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 8113162 [H]