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The map label for this gene is yhcY [H]

Identifier: 52145221

GI number: 52145221

Start: 5216536

End: 5218107

Strand: Reverse

Name: yhcY [H]

Synonym: BCZK5109

Alternate gene names: 52145221

Gene position: 5218107-5216536 (Counterclockwise)

Preceding gene: 52145223

Following gene: 52145220

Centisome position: 98.44

GC content: 35.69

Gene sequence:

>1572_bases
ATGTTTCAAGAGAATCGTACAAATGAATTAGTTATATTAAAAGAAATTGCAGAAACGCTAAATACATCAAATGATACATA
CCATGTATTGCAAGCAGTGCTAGAAAAATTACTTAGTGTAACAGGTTTAACGACAGGATGGATATTTCTTGCGGATGAAA
ATGGTAGATATACAAAATTAATTGATTATCAATTACCAGAGGCACTTACATATGAAAATAAACGCCCGATGTGTGAAGGG
GAATGTTGGTGTTTACGTGGCTTTGTGGATGGAAAGTTAGAGAGAGCTGTTAATATTATTGAATGTAAAAGAATTAATAA
TGCAATTGAATATAATTGGGGAGATACAGAAGGGATTCTTCATCATGCTACGGTTCCTTTAAAGGCTGGAGGAGAAAAAT
TTGGTTTGTTAAATGTGGCCAGCCCAGGTAAAACACATTTTTCAGAAGAAGAATTAGTATTGCTTCAATCAGTTGCTTTC
CAAATTGGAACGGCTTTAAAACGAGCAAAGTTATATGAAAATGAAAAGCGAAGAGCGCATTATTATGTGAAATTAGAACG
TTTCATTCAAGTTTTAAGAACGATTCATCAATTTAATATATTGCCTGAAAAAGTTGTAAATCAATTAGGTGAAGTGTTTC
AGTGGAATCAAGTGGCGTTTTTTATTAGGGAAGAAAAAGAATTATCTTTGCGGGCATCTTATTGCCAGGAAGAATTGCAC
GAGGATATAAAAGAAGCAGCGAAAGAAGCATTAGAAAAAGGTGAACCTATTTTATTAAACGATCAAATCAGTCATAAGGT
AGCCTCTAATAGGACGGTTATTGCCACACCAATACAGATTCAAACTCACATATTTGGTGTTTTATGCGTTAGTTCAAATT
ATGGTGAATTTGATGTGAATACGATAGATGTACTTCAAGCAATAACAAATCATATTTCCTTCGTGATAGAAAATTTAAGG
TTAAATGAGCAACGACGCGAACTTGTACGAATGGAAGAAAGAAATCGGTTAGCAAGGGACTTACATGATTCCGTCTCACA
AAAGCTATTTTCGTTAACCTTTATGACAAAGGGCGCTGAGGCGGTCTTAAAAGGTCAAAATGAAAAGGTGGACCGATCTT
TGCATGAGATGCGTGAACTAGCGCAAGGAGCTTTAAAAGAAATGAGAACGTTAATTTGGCAACTACGTCCAGCGGGTTTG
GAGAAAGGATTATTACCAGCTTTAAAGCAATATGGTGAAAGTTTGGGGTTGAAAATTCGGGAACAAGTTACAGGTGTCCG
CGATTTGCCGCGCGTAGTAGAGGAAGCGTTATGGAGAATTGGACAAGAAGCTTTAAATAACGTAAGTAAGCATGCGAATG
TTAGAGAAGCGACGATTTATTTCAAAGTGACTGAGAAGAATGTATCATTAGAAATAGTCGATCAAGGAAACGGCTTTGTA
GAAAAGAATATAAAAGAGAAGAAATCACTTGGCATGACTACGATGCGCGAAAGAGTAGGATTAGTCGGTGGAACAATTAA
AATTGTAAGTGATAAAAAAAGAACAAGTGTAAAAGTAAACGTACCATTATGA

Upstream 100 bases:

>100_bases
ATGTTTTCACCATTATATCAATGTTATGAATAAGTAAAAAGTGAAAAGTAGATGATTTATGTTAGGAACTATGTAAAATC
TTGTATGTAGGAGACGAATT

Downstream 100 bases:

>100_bases
TGTGAAAATGAGGGAAGTTTGTGAAAATAAAAGTATTATTAGTTGATGATCATACAGTCGTTTTAAAAGGATTAGCATTT
TTCTTAAGTACACAGGAAGA

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 523; Mature: 523

Protein sequence:

>523_residues
MFQENRTNELVILKEIAETLNTSNDTYHVLQAVLEKLLSVTGLTTGWIFLADENGRYTKLIDYQLPEALTYENKRPMCEG
ECWCLRGFVDGKLERAVNIIECKRINNAIEYNWGDTEGILHHATVPLKAGGEKFGLLNVASPGKTHFSEEELVLLQSVAF
QIGTALKRAKLYENEKRRAHYYVKLERFIQVLRTIHQFNILPEKVVNQLGEVFQWNQVAFFIREEKELSLRASYCQEELH
EDIKEAAKEALEKGEPILLNDQISHKVASNRTVIATPIQIQTHIFGVLCVSSNYGEFDVNTIDVLQAITNHISFVIENLR
LNEQRRELVRMEERNRLARDLHDSVSQKLFSLTFMTKGAEAVLKGQNEKVDRSLHEMRELAQGALKEMRTLIWQLRPAGL
EKGLLPALKQYGESLGLKIREQVTGVRDLPRVVEEALWRIGQEALNNVSKHANVREATIYFKVTEKNVSLEIVDQGNGFV
EKNIKEKKSLGMTTMRERVGLVGGTIKIVSDKKRTSVKVNVPL

Sequences:

>Translated_523_residues
MFQENRTNELVILKEIAETLNTSNDTYHVLQAVLEKLLSVTGLTTGWIFLADENGRYTKLIDYQLPEALTYENKRPMCEG
ECWCLRGFVDGKLERAVNIIECKRINNAIEYNWGDTEGILHHATVPLKAGGEKFGLLNVASPGKTHFSEEELVLLQSVAF
QIGTALKRAKLYENEKRRAHYYVKLERFIQVLRTIHQFNILPEKVVNQLGEVFQWNQVAFFIREEKELSLRASYCQEELH
EDIKEAAKEALEKGEPILLNDQISHKVASNRTVIATPIQIQTHIFGVLCVSSNYGEFDVNTIDVLQAITNHISFVIENLR
LNEQRRELVRMEERNRLARDLHDSVSQKLFSLTFMTKGAEAVLKGQNEKVDRSLHEMRELAQGALKEMRTLIWQLRPAGL
EKGLLPALKQYGESLGLKIREQVTGVRDLPRVVEEALWRIGQEALNNVSKHANVREATIYFKVTEKNVSLEIVDQGNGFV
EKNIKEKKSLGMTTMRERVGLVGGTIKIVSDKKRTSVKVNVPL
>Mature_523_residues
MFQENRTNELVILKEIAETLNTSNDTYHVLQAVLEKLLSVTGLTTGWIFLADENGRYTKLIDYQLPEALTYENKRPMCEG
ECWCLRGFVDGKLERAVNIIECKRINNAIEYNWGDTEGILHHATVPLKAGGEKFGLLNVASPGKTHFSEEELVLLQSVAF
QIGTALKRAKLYENEKRRAHYYVKLERFIQVLRTIHQFNILPEKVVNQLGEVFQWNQVAFFIREEKELSLRASYCQEELH
EDIKEAAKEALEKGEPILLNDQISHKVASNRTVIATPIQIQTHIFGVLCVSSNYGEFDVNTIDVLQAITNHISFVIENLR
LNEQRRELVRMEERNRLARDLHDSVSQKLFSLTFMTKGAEAVLKGQNEKVDRSLHEMRELAQGALKEMRTLIWQLRPAGL
EKGLLPALKQYGESLGLKIREQVTGVRDLPRVVEEALWRIGQEALNNVSKHANVREATIYFKVTEKNVSLEIVDQGNGFV
EKNIKEKKSLGMTTMRERVGLVGGTIKIVSDKKRTSVKVNVPL

Specific function: Member of the two-component regulatory system yhcY/yhcZ. Probably activates yhcZ by phosphorylation [H]

COG id: COG2203

COG function: function code T; FOG: GAF domain

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1787474, Length=197, Percent_Identity=27.4111675126904, Blast_Score=71, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR011712 [H]

Pfam domain/function: PF01590 GAF; PF02518 HATPase_c; PF07730 HisKA_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 59705; Mature: 59705

Theoretical pI: Translated: 7.64; Mature: 7.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFQENRTNELVILKEIAETLNTSNDTYHVLQAVLEKLLSVTGLTTGWIFLADENGRYTKL
CCCCCCCCCEEEHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEEE
IDYQLPEALTYENKRPMCEGECWCLRGFVDGKLERAVNIIECKRINNAIEYNWGDTEGIL
EECCCCHHHCCCCCCCCCCCCCEEEECHHCHHHHHHHHHHHHHHCCCCEEECCCCCCCCE
HHATVPLKAGGEKFGLLNVASPGKTHFSEEELVLLQSVAFQIGTALKRAKLYENEKRRAH
EECCCEECCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHH
YYVKLERFIQVLRTIHQFNILPEKVVNQLGEVFQWNQVAFFIREEKELSLRASYCQEELH
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHH
EDIKEAAKEALEKGEPILLNDQISHKVASNRTVIATPIQIQTHIFGVLCVSSNYGEFDVN
HHHHHHHHHHHHCCCCEEECCHHHHHHHCCCEEEEECCEEEEEEEEEEEEECCCCCCCCH
TIDVLQAITNHISFVIENLRLNEQRRELVRMEERNRLARDLHDSVSQKLFSLTFMTKGAE
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
AVLKGQNEKVDRSLHEMRELAQGALKEMRTLIWQLRPAGLEKGLLPALKQYGESLGLKIR
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCHH
EQVTGVRDLPRVVEEALWRIGQEALNNVSKHANVREATIYFKVTEKNVSLEIVDQGNGFV
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCEEEEEECCCCCH
EKNIKEKKSLGMTTMRERVGLVGGTIKIVSDKKRTSVKVNVPL
HHHHHHHHHCCHHHHHHHHHHCCCEEEEEECCCCCEEEEECCC
>Mature Secondary Structure
MFQENRTNELVILKEIAETLNTSNDTYHVLQAVLEKLLSVTGLTTGWIFLADENGRYTKL
CCCCCCCCCEEEHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEEE
IDYQLPEALTYENKRPMCEGECWCLRGFVDGKLERAVNIIECKRINNAIEYNWGDTEGIL
EECCCCHHHCCCCCCCCCCCCCEEEECHHCHHHHHHHHHHHHHHCCCCEEECCCCCCCCE
HHATVPLKAGGEKFGLLNVASPGKTHFSEEELVLLQSVAFQIGTALKRAKLYENEKRRAH
EECCCEECCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHH
YYVKLERFIQVLRTIHQFNILPEKVVNQLGEVFQWNQVAFFIREEKELSLRASYCQEELH
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHH
EDIKEAAKEALEKGEPILLNDQISHKVASNRTVIATPIQIQTHIFGVLCVSSNYGEFDVN
HHHHHHHHHHHHCCCCEEECCHHHHHHHCCCEEEEECCEEEEEEEEEEEEECCCCCCCCH
TIDVLQAITNHISFVIENLRLNEQRRELVRMEERNRLARDLHDSVSQKLFSLTFMTKGAE
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
AVLKGQNEKVDRSLHEMRELAQGALKEMRTLIWQLRPAGLEKGLLPALKQYGESLGLKIR
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCHH
EQVTGVRDLPRVVEEALWRIGQEALNNVSKHANVREATIYFKVTEKNVSLEIVDQGNGFV
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCEEEEEECCCCCH
EKNIKEKKSLGMTTMRERVGLVGGTIKIVSDKKRTSVKVNVPL
HHHHHHHHHCCHHHHHHHHHHCCCEEEEEECCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]