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The map label for this gene is gpmA [H]

Identifier: 52143005

GI number: 52143005

Start: 2363558

End: 2364295

Strand: Direct

Name: gpmA [H]

Synonym: BCZK2234

Alternate gene names: 52143005

Gene position: 2363558-2364295 (Clockwise)

Preceding gene: 52143004

Following gene: 52143003

Centisome position: 44.59

GC content: 35.64

Gene sequence:

>738_bases
ATGATAAAACTTGTACTTATTCGTCACGGACAGAGTTTATGGAATCTTGAAAATCGTTTTACTGGATGGACAGATGTAGA
TTTATCAGAGAATGGATTAAGTGAAGCGAGAGAGGCAGGAGCGATATTAAAGAAAAATGGATATACTTTTGATGTAGCTT
ATACATCTGTATTAAAACGAGCAATTCGGACGTTATGGATTGTACTTCATGAAATGAATCTTGCCTGGGTACCAGTACAT
AAATCTTGGAAGCTAAATGAAAGACATTATGGTGCATTGCAAGGTTTGAATAAAGATGAAACCGCGCAAAAATATGGTGA
GGAGCAAGTTCATATTTGGAGAAGAAGTATTGATGTAAGACCACCTGCTCTTACTGAGGATGATCCCAGGTATGAAATGA
ATGATCCAAGATATAAAGCACTGAAAAAAGGTGAGTTTCCATTGACAGAATGTTTAGTGGATACGGAGAAAAGAGTACTT
GATTATTGGCATTCAGAAATTGCGCCGAAATTAAAGAATGGTAACAAAGTAATCATTTCATCACATGGTAACACAATTCG
CTCGCTAGTAAAATATTTAGATAATCTTTCAAGCGATGGTGTTGTTTCACTAAATATTCCAACGAGTATACCGCTCGTTT
ATGAATTAGACGAAAATTTACGTCCGATTCGCCATTATTACTTAAGTATGGATGGAGAAGTACCTGAAGGGGAAATTCCG
AAACATATTTCTTTTTAA

Upstream 100 bases:

>100_bases
AGCTATCATAGAGTGAATGGATAAAAAGATACATTACTAGATACTTTATACGTGTACGCAATGGAACAATAAAATTCACA
TTTCCGAGAGGGGAATTATA

Downstream 100 bases:

>100_bases
CATGAAAATTTGAAACACATGCTTGTCTACATATACAATGTAGATTCAAGGTAAAAGACGTGGCACCTTCTAATGTATAT
GCGATGTAGCTAAATTTAGA

Product: phosphoglyceromutase

Products: NA

Alternate protein names: BPG-dependent PGAM 1; PGAM 1; Phosphoglyceromutase 1; dPGM 1 [H]

Number of amino acids: Translated: 245; Mature: 245

Protein sequence:

>245_residues
MIKLVLIRHGQSLWNLENRFTGWTDVDLSENGLSEAREAGAILKKNGYTFDVAYTSVLKRAIRTLWIVLHEMNLAWVPVH
KSWKLNERHYGALQGLNKDETAQKYGEEQVHIWRRSIDVRPPALTEDDPRYEMNDPRYKALKKGEFPLTECLVDTEKRVL
DYWHSEIAPKLKNGNKVIISSHGNTIRSLVKYLDNLSSDGVVSLNIPTSIPLVYELDENLRPIRHYYLSMDGEVPEGEIP
KHISF

Sequences:

>Translated_245_residues
MIKLVLIRHGQSLWNLENRFTGWTDVDLSENGLSEAREAGAILKKNGYTFDVAYTSVLKRAIRTLWIVLHEMNLAWVPVH
KSWKLNERHYGALQGLNKDETAQKYGEEQVHIWRRSIDVRPPALTEDDPRYEMNDPRYKALKKGEFPLTECLVDTEKRVL
DYWHSEIAPKLKNGNKVIISSHGNTIRSLVKYLDNLSSDGVVSLNIPTSIPLVYELDENLRPIRHYYLSMDGEVPEGEIP
KHISF
>Mature_245_residues
MIKLVLIRHGQSLWNLENRFTGWTDVDLSENGLSEAREAGAILKKNGYTFDVAYTSVLKRAIRTLWIVLHEMNLAWVPVH
KSWKLNERHYGALQGLNKDETAQKYGEEQVHIWRRSIDVRPPALTEDDPRYEMNDPRYKALKKGEFPLTECLVDTEKRVL
DYWHSEIAPKLKNGNKVIISSHGNTIRSLVKYLDNLSSDGVVSLNIPTSIPLVYELDENLRPIRHYYLSMDGEVPEGEIP
KHISF

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate [H]

COG id: COG0588

COG function: function code G; Phosphoglycerate mutase 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily [H]

Homologues:

Organism=Homo sapiens, GI50593010, Length=234, Percent_Identity=50, Blast_Score=255, Evalue=2e-68,
Organism=Homo sapiens, GI4505753, Length=234, Percent_Identity=53.4188034188034, Blast_Score=251, Evalue=4e-67,
Organism=Homo sapiens, GI71274132, Length=234, Percent_Identity=50.8547008547009, Blast_Score=236, Evalue=1e-62,
Organism=Homo sapiens, GI4502445, Length=243, Percent_Identity=44.4444444444444, Blast_Score=230, Evalue=1e-60,
Organism=Homo sapiens, GI40353764, Length=243, Percent_Identity=44.4444444444444, Blast_Score=230, Evalue=1e-60,
Organism=Homo sapiens, GI310129614, Length=160, Percent_Identity=56.875, Blast_Score=172, Evalue=4e-43,
Organism=Escherichia coli, GI1786970, Length=234, Percent_Identity=62.8205128205128, Blast_Score=316, Evalue=1e-87,
Organism=Saccharomyces cerevisiae, GI6322697, Length=229, Percent_Identity=50.6550218340611, Blast_Score=227, Evalue=1e-60,
Organism=Saccharomyces cerevisiae, GI6324516, Length=280, Percent_Identity=31.4285714285714, Blast_Score=125, Evalue=7e-30,
Organism=Saccharomyces cerevisiae, GI6320183, Length=283, Percent_Identity=29.6819787985866, Blast_Score=115, Evalue=6e-27,
Organism=Drosophila melanogaster, GI85725270, Length=224, Percent_Identity=52.2321428571429, Blast_Score=233, Evalue=1e-61,
Organism=Drosophila melanogaster, GI85725272, Length=224, Percent_Identity=52.2321428571429, Blast_Score=233, Evalue=1e-61,
Organism=Drosophila melanogaster, GI24650981, Length=224, Percent_Identity=52.2321428571429, Blast_Score=233, Evalue=1e-61,
Organism=Drosophila melanogaster, GI24646216, Length=224, Percent_Identity=50.8928571428571, Blast_Score=230, Evalue=6e-61,
Organism=Drosophila melanogaster, GI28571815, Length=218, Percent_Identity=39.9082568807339, Blast_Score=174, Evalue=3e-44,
Organism=Drosophila melanogaster, GI28571817, Length=218, Percent_Identity=39.9082568807339, Blast_Score=174, Evalue=4e-44,
Organism=Drosophila melanogaster, GI24648979, Length=218, Percent_Identity=39.9082568807339, Blast_Score=174, Evalue=5e-44,

Paralogues:

None

Copy number: 960 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR005952 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: =5.4.2.1 [H]

Molecular weight: Translated: 28309; Mature: 28309

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: PS00175 PG_MUTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKLVLIRHGQSLWNLENRFTGWTDVDLSENGLSEAREAGAILKKNGYTFDVAYTSVLKR
CEEEEEEECCCHHHHHHHHCCCCEECCCCCCCHHHHHHCCCEEECCCCEEEHHHHHHHHH
AIRTLWIVLHEMNLAWVPVHKSWKLNERHYGALQGLNKDETAQKYGEEQVHIWRRSIDVR
HHHHHHHHHHHCCEEEEECCCCCCCCCCHHHHHCCCCCCHHHHHHCCHHHHHHHHHCCCC
PPALTEDDPRYEMNDPRYKALKKGEFPLTECLVDTEKRVLDYWHSEIAPKLKNGNKVIIS
CCCCCCCCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCHHHCCCCEEEEE
SHGNTIRSLVKYLDNLSSDGVVSLNIPTSIPLVYELDENLRPIRHYYLSMDGEVPEGEIP
CCCHHHHHHHHHHHCCCCCCEEEEECCCCCCEEEECCCCCCHHHHHEEECCCCCCCCCCC
KHISF
CCCCC
>Mature Secondary Structure
MIKLVLIRHGQSLWNLENRFTGWTDVDLSENGLSEAREAGAILKKNGYTFDVAYTSVLKR
CEEEEEEECCCHHHHHHHHCCCCEECCCCCCCHHHHHHCCCEEECCCCEEEHHHHHHHHH
AIRTLWIVLHEMNLAWVPVHKSWKLNERHYGALQGLNKDETAQKYGEEQVHIWRRSIDVR
HHHHHHHHHHHCCEEEEECCCCCCCCCCHHHHHCCCCCCHHHHHHCCHHHHHHHHHCCCC
PPALTEDDPRYEMNDPRYKALKKGEFPLTECLVDTEKRVLDYWHSEIAPKLKNGNKVIIS
CCCCCCCCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCHHHCCCCEEEEE
SHGNTIRSLVKYLDNLSSDGVVSLNIPTSIPLVYELDENLRPIRHYYLSMDGEVPEGEIP
CCCHHHHHHHHHHHCCCCCCEEEEECCCCCCEEEECCCCCCHHHHHEEECCCCCCCCCCC
KHISF
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA