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The map label for this gene is rpoD [H]

Identifier: 52142997

GI number: 52142997

Start: 2370728

End: 2371267

Strand: Direct

Name: rpoD [H]

Synonym: BCZK2243

Alternate gene names: 52142997

Gene position: 2370728-2371267 (Clockwise)

Preceding gene: 52142996

Following gene: 52142995

Centisome position: 44.72

GC content: 30.37

Gene sequence:

>540_bases
GTGGAAATGGAACAGACGTTTATTGAAAAGTGTAATCATGATGAGCTGGACTATGTTATAAAAGAATATTGGCAAGATGT
ATGGAATTATTCATTTATTATTACGAAAGATCCACACTTATCAGATGATATTACGCAAGATGTATTTATAAAGGTATTTA
AAAATTGGAATTCATTTCGAAAGGAGTCATCTATTAAAACGTGGATATTAAAAATCACAAGAAATACGGCAATAAACTAT
TTGAAATCATCTTATTTTAAAAGAATATCTTTAGTAGGATTTTTTAGTGACGATAAACAAACTCTGTCGGCAGAACAAGA
GTTTTTTAAGCAAGAAGAAATGAATGATGTGTGGAAAGTTGTATTAAAACTACCTAAAAAGCACCGCGAAATAATAATAT
TGGACGCAAAATATGAACTATCTTATGAAGAAATGGCTGAAACACTAGGAGTATCCATTGGAACTGTAAAATCTAGATTA
AGTAGAGCAAGAAGTAAGGTTTCAAAATTAATAGGGGAGGGTGGTAGTGATGAACAATAA

Upstream 100 bases:

>100_bases
CTCGAACTAAATGGAACAAATGAAACTGGTATCTTGTCTATATATTGAAACCATAATAAAAGTGAGGGTAGTTTTATGTT
TATTCAAATAAGTTTGAGGT

Downstream 100 bases:

>100_bases
ACAAAATCCTGACTGGTATAGTAAATTAAAAAACGGCCCAATGGAACACCGTAAAGATGAAGAAGAATATATTTATAACA
TAAAGAAATCTATATACCAA

Product: RNA polymerase sigma-70 factor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 179; Mature: 179

Protein sequence:

>179_residues
MEMEQTFIEKCNHDELDYVIKEYWQDVWNYSFIITKDPHLSDDITQDVFIKVFKNWNSFRKESSIKTWILKITRNTAINY
LKSSYFKRISLVGFFSDDKQTLSAEQEFFKQEEMNDVWKVVLKLPKKHREIIILDAKYELSYEEMAETLGVSIGTVKSRL
SRARSKVSKLIGEGGSDEQ

Sequences:

>Translated_179_residues
MEMEQTFIEKCNHDELDYVIKEYWQDVWNYSFIITKDPHLSDDITQDVFIKVFKNWNSFRKESSIKTWILKITRNTAINY
LKSSYFKRISLVGFFSDDKQTLSAEQEFFKQEEMNDVWKVVLKLPKKHREIIILDAKYELSYEEMAETLGVSIGTVKSRL
SRARSKVSKLIGEGGSDEQ
>Mature_179_residues
MEMEQTFIEKCNHDELDYVIKEYWQDVWNYSFIITKDPHLSDDITQDVFIKVFKNWNSFRKESSIKTWILKITRNTAINY
LKSSYFKRISLVGFFSDDKQTLSAEQEFFKQEEMNDVWKVVLKLPKKHREIIILDAKYELSYEEMAETLGVSIGTVKSRL
SRARSKVSKLIGEGGSDEQ

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor contributes to oxidative stress resistance [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788926, Length=142, Percent_Identity=35.2112676056338, Blast_Score=72, Evalue=3e-14,

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR014296
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR013325
- InterPro:   IPR013324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 21185; Mature: 21185

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: PS01063 SIGMA70_ECF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEMEQTFIEKCNHDELDYVIKEYWQDVWNYSFIITKDPHLSDDITQDVFIKVFKNWNSFR
CCHHHHHHHHCCCCHHHHHHHHHHHHHHCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHH
KESSIKTWILKITRNTAINYLKSSYFKRISLVGFFSDDKQTLSAEQEFFKQEEMNDVWKV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHH
VLKLPKKHREIIILDAKYELSYEEMAETLGVSIGTVKSRLSRARSKVSKLIGEGGSDEQ
HHHCCCCCCEEEEEECCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MEMEQTFIEKCNHDELDYVIKEYWQDVWNYSFIITKDPHLSDDITQDVFIKVFKNWNSFR
CCHHHHHHHHCCCCHHHHHHHHHHHHHHCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHH
KESSIKTWILKITRNTAINYLKSSYFKRISLVGFFSDDKQTLSAEQEFFKQEEMNDVWKV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHH
VLKLPKKHREIIILDAKYELSYEEMAETLGVSIGTVKSRLSRARSKVSKLIGEGGSDEQ
HHHCCCCCCEEEEEECCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]