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The map label for this gene is araC [H]

Identifier: 52142914

GI number: 52142914

Start: 2458006

End: 2459109

Strand: Direct

Name: araC [H]

Synonym: BCZK2326

Alternate gene names: 52142914

Gene position: 2458006-2459109 (Clockwise)

Preceding gene: 52142916

Following gene: 52142911

Centisome position: 46.37

GC content: 29.53

Gene sequence:

>1104_bases
GTGAAGGAAATGAATGAATATATACAGCAGATGATTGACTGGATTGAGGTCAATTTAAAAAAGGAATTTTCATTAGATGA
ATTGTCCCGTTATATGGGGTATTCTCCTTATTATTGTTCTTTTAAATTTCACCAAGTAACGGGTTTCAGTATTAGACGCT
ATGTTCTTCTTAGAAGGTTATATTTATCTATAGAAGATTTAAAGAATGGTAGGAAGATAATAGATATCGCATTGGATTAC
AATTATTCTTCGCAAGAGGCCTATAGTAGAGCTTTCAAGAATGTTTTTGGAATGAATCCAAGAGAATTTCAACTTAACCA
ATTGCCTATTCAATCATTTGTTAAACTCAATATAAATAAGGAAGGAGAGTTTAATATGAATATTTCTAGAAAAATAGAGG
TTGAGCAATTACGAAATGCGAAGAGTGAGCTGTTTGATAAAGATGTATTAAACATATTGAATGGTCAAATGATGTATGAA
GAATTTAAAAATGAAAAGCTAATGGGTGATTCTGATTACGCACCATTTAATGAAGCGATGTGTGTAAACCGAGTTACTAC
ACTAGTTTTTAATGAAGAATTTATTAAGACAAGGGCAGCAGGACATAACAGTTCAGTAGAAAGTTACACAAAAAAGGTTA
TAGATCCATTAAAGAAACTTTTTAAGAAAGAGTATAAATGTATTGTTTTATGGTTTGGTGAAGATATGTTTTGTCAAATG
AACTTACTTACAATACTTTCATACCTTGAACAGTCGTTTTATGAGGGGAAGGTATACTTAAATAGCTTTAGAGAAGATGA
ATTTAAAGTAAATCAAATTGAACTTGAATTAGGAAATTATTCTTCGGTATACAATGAAGTATTAGTAAATCATAAAAAGA
CTTTCTATAAGGTACCACCTGTAATGTATCAGGCTATAGATCTATATTTAAAAATGCTAAAAGAAGATAATACTGTAATG
AAATTTCTCTCTAAAAATAAAGATTTATCAACTCAAGAATTATTAACAAAGTTGTTTCAGCTATTTCCAACAATCGGATA
TGGGGATTCCCAGTACATAGAGCTGATTAATAAAATAAAGAAGAAAGCTACACCAAAAATATAG

Upstream 100 bases:

>100_bases
ACTAATACTCATATTTAGATTTTACAGAATGGCTCATGTTATAAAACACAAGAAATATCAAAAGAATGAAATGCACTTCC
CTTATACTTTTATATAAGGA

Downstream 100 bases:

>100_bases
GTGCAGCTTTCTTTTTACAATTGTTCAAGTAACTCTAATTCTCCCTCTACAAATAACATTAGTTCTTTAATTATTTCGCC
AGAAAAATCAAAACGAATTC

Product: AraC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 367; Mature: 367

Protein sequence:

>367_residues
MKEMNEYIQQMIDWIEVNLKKEFSLDELSRYMGYSPYYCSFKFHQVTGFSIRRYVLLRRLYLSIEDLKNGRKIIDIALDY
NYSSQEAYSRAFKNVFGMNPREFQLNQLPIQSFVKLNINKEGEFNMNISRKIEVEQLRNAKSELFDKDVLNILNGQMMYE
EFKNEKLMGDSDYAPFNEAMCVNRVTTLVFNEEFIKTRAAGHNSSVESYTKKVIDPLKKLFKKEYKCIVLWFGEDMFCQM
NLLTILSYLEQSFYEGKVYLNSFREDEFKVNQIELELGNYSSVYNEVLVNHKKTFYKVPPVMYQAIDLYLKMLKEDNTVM
KFLSKNKDLSTQELLTKLFQLFPTIGYGDSQYIELINKIKKKATPKI

Sequences:

>Translated_367_residues
MKEMNEYIQQMIDWIEVNLKKEFSLDELSRYMGYSPYYCSFKFHQVTGFSIRRYVLLRRLYLSIEDLKNGRKIIDIALDY
NYSSQEAYSRAFKNVFGMNPREFQLNQLPIQSFVKLNINKEGEFNMNISRKIEVEQLRNAKSELFDKDVLNILNGQMMYE
EFKNEKLMGDSDYAPFNEAMCVNRVTTLVFNEEFIKTRAAGHNSSVESYTKKVIDPLKKLFKKEYKCIVLWFGEDMFCQM
NLLTILSYLEQSFYEGKVYLNSFREDEFKVNQIELELGNYSSVYNEVLVNHKKTFYKVPPVMYQAIDLYLKMLKEDNTVM
KFLSKNKDLSTQELLTKLFQLFPTIGYGDSQYIELINKIKKKATPKI
>Mature_367_residues
MKEMNEYIQQMIDWIEVNLKKEFSLDELSRYMGYSPYYCSFKFHQVTGFSIRRYVLLRRLYLSIEDLKNGRKIIDIALDY
NYSSQEAYSRAFKNVFGMNPREFQLNQLPIQSFVKLNINKEGEFNMNISRKIEVEQLRNAKSELFDKDVLNILNGQMMYE
EFKNEKLMGDSDYAPFNEAMCVNRVTTLVFNEEFIKTRAAGHNSSVESYTKKVIDPLKKLFKKEYKCIVLWFGEDMFCQM
NLLTILSYLEQSFYEGKVYLNSFREDEFKVNQIELELGNYSSVYNEVLVNHKKTFYKVPPVMYQAIDLYLKMLKEDNTVM
KFLSKNKDLSTQELLTKLFQLFPTIGYGDSQYIELINKIKKKATPKI

Specific function: Binds to the right arm of the replication origin oriC of the chromosome. Rob binding may influence the formation of the nucleoprotein structure, required for oriC function in the initiation of replication [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790857, Length=133, Percent_Identity=33.0827067669173, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790497, Length=98, Percent_Identity=33.6734693877551, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI87081928, Length=106, Percent_Identity=31.1320754716981, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010499
- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR018062
- InterPro:   IPR020449
- InterPro:   IPR018060
- InterPro:   IPR011256 [H]

Pfam domain/function: PF06445 AraC_E_bind; PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 43591; Mature: 43591

Theoretical pI: Translated: 8.46; Mature: 8.46

Prosite motif: PS00041 HTH_ARAC_FAMILY_1 ; PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEMNEYIQQMIDWIEVNLKKEFSLDELSRYMGYSPYYCSFKFHQVTGFSIRRYVLLRRL
CCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEEEEEEECCHHHHHHHHHHHH
YLSIEDLKNGRKIIDIALDYNYSSQEAYSRAFKNVFGMNPREFQLNQLPIQSFVKLNINK
HHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHHHHHCCCCCCEEHHHCCHHHHHEEECCC
EGEFNMNISRKIEVEQLRNAKSELFDKDVLNILNGQMMYEEFKNEKLMGDSDYAPFNEAM
CCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCCCHHHH
CVNRVTTLVFNEEFIKTRAAGHNSSVESYTKKVIDPLKKLFKKEYKCIVLWFGEDMFCQM
HHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHH
NLLTILSYLEQSFYEGKVYLNSFREDEFKVNQIELELGNYSSVYNEVLVNHKKTFYKVPP
HHHHHHHHHHHHHHCCHHHHHCCCCCCEEEEEEEEEECCHHHHHHHHHHHCCHHHEECCH
VMYQAIDLYLKMLKEDNTVMKFLSKNKDLSTQELLTKLFQLFPTIGYGDSQYIELINKIK
HHHHHHHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
KKATPKI
HHCCCCC
>Mature Secondary Structure
MKEMNEYIQQMIDWIEVNLKKEFSLDELSRYMGYSPYYCSFKFHQVTGFSIRRYVLLRRL
CCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEEEEEEECCHHHHHHHHHHHH
YLSIEDLKNGRKIIDIALDYNYSSQEAYSRAFKNVFGMNPREFQLNQLPIQSFVKLNINK
HHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHHHHHCCCCCCEEHHHCCHHHHHEEECCC
EGEFNMNISRKIEVEQLRNAKSELFDKDVLNILNGQMMYEEFKNEKLMGDSDYAPFNEAM
CCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCCCHHHH
CVNRVTTLVFNEEFIKTRAAGHNSSVESYTKKVIDPLKKLFKKEYKCIVLWFGEDMFCQM
HHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHH
NLLTILSYLEQSFYEGKVYLNSFREDEFKVNQIELELGNYSSVYNEVLVNHKKTFYKVPP
HHHHHHHHHHHHHHCCHHHHHCCCCCCEEEEEEEEEECCHHHHHHHHHHHCCHHHEECCH
VMYQAIDLYLKMLKEDNTVMKFLSKNKDLSTQELLTKLFQLFPTIGYGDSQYIELINKIK
HHHHHHHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
KKATPKI
HHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]