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The map label for this gene is CYP106A2 [H]

Identifier: 52142863

GI number: 52142863

Start: 2510458

End: 2511672

Strand: Direct

Name: CYP106A2 [H]

Synonym: BCZK2377

Alternate gene names: 52142863

Gene position: 2510458-2511672 (Clockwise)

Preceding gene: 52142864

Following gene: 52142862

Centisome position: 47.36

GC content: 32.76

Gene sequence:

>1215_bases
ATGGCTTCGCCTGAAAATGTGATTTTAGTTCATGAAATTTCAAAGCTGAAAACGAAAGAAGAATTGTGGAATCCATATGA
GTGGTATCAATTTATGAGGGATAATCACCCCGTATATTATGATGAAGAGCAAGATGTTTGGAATGTATTTTTGTATGAGG
ATGTAAATCGAGTTTTATCGGATTATCGCTTGTTTTCTAGTAGAAGAGAACGAAGACAATTCTCAATTCCCCCTTTAGAA
ACTCGAATAAATATCAATTCTACTGATCCACCAGAACATCGTAATGTACGTTCTATCGTTTCTAAAGCATTTACTCCAAG
AAGTTTAGAACAATGGAAACCTCGAATACAGGCTATCGCAGATGAACTTGTAAAAGATATTGAAAAGTTTAGTGAAGTTG
ATATCGTTGAACAGTTTGCTGCCTCTTTACCTGTTACCGTCATATCCGATTTATTAGGAGTGCCAACAACTGACCGTAAA
AAAATTAAAGCATGGTCTGATATTTTATTTATGCCGTATAGTAAAGAAAAGTTTAATGATCTGGATGCAGAAAAGGGGAT
AGCACTAAATGAATTTAAAGCATATCTTCTACCGATCGTTCAGGAAAAGAGATACCTTTTAACCGATGATATTATCTCAG
ATTTAATAAGAGCTGAGTATGAAGGCGAAAGATTAACTGATGAAGAAATTGTTATTTTTTCATTAGGTTTATTAGCCGCT
GGTAATGAAACAACTACAAATTTAATTATTAATAGTTTTTATTGTTTCTTAATGGATTCACCTGGAACATATAAAGAATT
AAGAAAAGAACCTAAATTAATTTCAAAAGCGATTGAGGAAGTATTACGCTATCGCTTTCCTGTTACATTAGCTAGGAGAA
TTACAGAGGACACCAATATATTTGGACCTTTAATGAAAAAGGATCAAATGGTTGTTGCGTGGGTTAGTGCAGCAAACTTA
GATGAGAAAAAGTTTGCACAAGCCTCTAAATTTAATATACACCGAATAGGAAATGAAAAGCATTTAACATTTGGTAAAGG
TGCTCACTTTTGCTTAGGGGCACCACTTGCACGTTTAGAAGCTGAGATTGCATTAAGTACTTTTATAAATGCTTTTGAAA
AAATAGAGTTATCTTCATCTTTCGATTTAGAAAAATGTATATTGAAAAATGAACAAACTTTGAAATTCTTACCTATCTGC
TTAAAAACTCAATAA

Upstream 100 bases:

>100_bases
AATTCCCTTTAATATATGTTAAAATAACATATGTTAGATTATACAACTTTGAATTACCGACCTATCACTTTTATTGTAAA
AGAAAAGGGAGGAAAGGACT

Downstream 100 bases:

>100_bases
ACTGTTCAGCAAGGTACTACTGTACCTTGTTTTTTATTTCTCAATTGTAAAATTTTAGTTAGTTATTTAGTATGGAAGTG
TGTGAATAGGAGTAGAGGAG

Product: cytochrome P450 family protein

Products: NA

Alternate protein names: Steroid 15-beta-hydroxylase; Steroid 15-beta-monooxygenase [H]

Number of amino acids: Translated: 404; Mature: 403

Protein sequence:

>404_residues
MASPENVILVHEISKLKTKEELWNPYEWYQFMRDNHPVYYDEEQDVWNVFLYEDVNRVLSDYRLFSSRRERRQFSIPPLE
TRININSTDPPEHRNVRSIVSKAFTPRSLEQWKPRIQAIADELVKDIEKFSEVDIVEQFAASLPVTVISDLLGVPTTDRK
KIKAWSDILFMPYSKEKFNDLDAEKGIALNEFKAYLLPIVQEKRYLLTDDIISDLIRAEYEGERLTDEEIVIFSLGLLAA
GNETTTNLIINSFYCFLMDSPGTYKELRKEPKLISKAIEEVLRYRFPVTLARRITEDTNIFGPLMKKDQMVVAWVSAANL
DEKKFAQASKFNIHRIGNEKHLTFGKGAHFCLGAPLARLEAEIALSTFINAFEKIELSSSFDLEKCILKNEQTLKFLPIC
LKTQ

Sequences:

>Translated_404_residues
MASPENVILVHEISKLKTKEELWNPYEWYQFMRDNHPVYYDEEQDVWNVFLYEDVNRVLSDYRLFSSRRERRQFSIPPLE
TRININSTDPPEHRNVRSIVSKAFTPRSLEQWKPRIQAIADELVKDIEKFSEVDIVEQFAASLPVTVISDLLGVPTTDRK
KIKAWSDILFMPYSKEKFNDLDAEKGIALNEFKAYLLPIVQEKRYLLTDDIISDLIRAEYEGERLTDEEIVIFSLGLLAA
GNETTTNLIINSFYCFLMDSPGTYKELRKEPKLISKAIEEVLRYRFPVTLARRITEDTNIFGPLMKKDQMVVAWVSAANL
DEKKFAQASKFNIHRIGNEKHLTFGKGAHFCLGAPLARLEAEIALSTFINAFEKIELSSSFDLEKCILKNEQTLKFLPIC
LKTQ
>Mature_403_residues
ASPENVILVHEISKLKTKEELWNPYEWYQFMRDNHPVYYDEEQDVWNVFLYEDVNRVLSDYRLFSSRRERRQFSIPPLET
RININSTDPPEHRNVRSIVSKAFTPRSLEQWKPRIQAIADELVKDIEKFSEVDIVEQFAASLPVTVISDLLGVPTTDRKK
IKAWSDILFMPYSKEKFNDLDAEKGIALNEFKAYLLPIVQEKRYLLTDDIISDLIRAEYEGERLTDEEIVIFSLGLLAAG
NETTTNLIINSFYCFLMDSPGTYKELRKEPKLISKAIEEVLRYRFPVTLARRITEDTNIFGPLMKKDQMVVAWVSAANLD
EKKFAQASKFNIHRIGNEKHLTFGKGAHFCLGAPLARLEAEIALSTFINAFEKIELSSSFDLEKCILKNEQTLKFLPICL
KTQ

Specific function: Has the capacity to hydroxylate certain steroids in the 15-beta position [H]

COG id: COG2124

COG function: function code Q; Cytochrome P450

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome P450 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001128
- InterPro:   IPR002397
- InterPro:   IPR017972 [H]

Pfam domain/function: PF00067 p450 [H]

EC number: NA

Molecular weight: Translated: 46878; Mature: 46747

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: PS00086 CYTOCHROME_P450

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASPENVILVHEISKLKTKEELWNPYEWYQFMRDNHPVYYDEEQDVWNVFLYEDVNRVLS
CCCCCCEEEEECHHHHHHHHHHCCHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHH
DYRLFSSRRERRQFSIPPLETRININSTDPPEHRNVRSIVSKAFTPRSLEQWKPRIQAIA
HHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHH
DELVKDIEKFSEVDIVEQFAASLPVTVISDLLGVPTTDRKKIKAWSDILFMPYSKEKFND
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHCEEECCCCHHHHCC
LDAEKGIALNEFKAYLLPIVQEKRYLLTDDIISDLIRAEYEGERLTDEEIVIFSLGLLAA
CCHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECHHCC
GNETTTNLIINSFYCFLMDSPGTYKELRKEPKLISKAIEEVLRYRFPVTLARRITEDTNI
CCCHHHHHHHHHEEEEEECCCCCHHHHHHCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCH
FGPLMKKDQMVVAWVSAANLDEKKFAQASKFNIHRIGNEKHLTFGKGAHFCLGAPLARLE
HHHHHCCCCEEEEEEECCCCCHHHHHHHHCCEEEECCCCCEEEECCCCCHHHCCCHHHHH
AEIALSTFINAFEKIELSSSFDLEKCILKNEQTLKFLPICLKTQ
HHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCEEEECEEECCC
>Mature Secondary Structure 
ASPENVILVHEISKLKTKEELWNPYEWYQFMRDNHPVYYDEEQDVWNVFLYEDVNRVLS
CCCCCEEEEECHHHHHHHHHHCCHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHH
DYRLFSSRRERRQFSIPPLETRININSTDPPEHRNVRSIVSKAFTPRSLEQWKPRIQAIA
HHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHH
DELVKDIEKFSEVDIVEQFAASLPVTVISDLLGVPTTDRKKIKAWSDILFMPYSKEKFND
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHCEEECCCCHHHHCC
LDAEKGIALNEFKAYLLPIVQEKRYLLTDDIISDLIRAEYEGERLTDEEIVIFSLGLLAA
CCHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECHHCC
GNETTTNLIINSFYCFLMDSPGTYKELRKEPKLISKAIEEVLRYRFPVTLARRITEDTNI
CCCHHHHHHHHHEEEEEECCCCCHHHHHHCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCH
FGPLMKKDQMVVAWVSAANLDEKKFAQASKFNIHRIGNEKHLTFGKGAHFCLGAPLARLE
HHHHHCCCCEEEEEEECCCCCHHHHHHHHCCEEEECCCCCEEEECCCCCHHHCCCHHHHH
AEIALSTFINAFEKIELSSSFDLEKCILKNEQTLKFLPICLKTQ
HHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCEEEECEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8232201; 109432; 6797409 [H]