Click here to switch to the map view.

The map label for this gene is yogA [H]

Identifier: 52142850

GI number: 52142850

Start: 2527070

End: 2528059

Strand: Direct

Name: yogA [H]

Synonym: BCZK2390

Alternate gene names: 52142850

Gene position: 2527070-2528059 (Clockwise)

Preceding gene: 52142851

Following gene: 52142848

Centisome position: 47.67

GC content: 36.36

Gene sequence:

>990_bases
ATGAAAGCAATTGTACATCAATATAAAAAAGGGGTAGAGGGGTTACAATATAAATTTTCATCTGAAACACATCCTAATGC
CGGTGAAGTAAAAGTAAAGTTAAAAGCAGCAGGATTAAATCATAGGGATTTATTTATTATAAACAATAGAAAAGAAATGG
ATCTACCGTTAGTAATAGGGTCAGATGGTGCAGGTATTGTTACAGAAATAGGAGAAGGTGTTTCAGCTGATTTATTGCAA
GCCGAGGTTATTATTAATCCTAGTATTGGATGGGAGAATATTGCCGAAGTACCAGAGTTACCAGAGGTGTTAGGTGGACC
AAAAGATGGAACGTTTGCTGAATATGTAATAGTGCCCGCTGAAAATGTAGTGGAAAAACCGTCATATCTTACTTGGGAAG
AGTCTGGCGTTTTGGCTTTATCAGCACTGACTGCATACAGAGCGCTTTTTACAAAGGGTAGATTGAAGTGTGGAGAACAT
GTTTTAATTCCAGGGATAGGCGGCGGTGTAGCGACATTTGCCATGTTATTTGCAAAAGCAATTGGCGCAAAAGTAAGTGT
TACGTCAAGGGTAGAAAACAAAAGAAAGTTTGCCGAAACATATGGCGCAGACTCTTCTTTTAATAGTTCTGGAAATTGGG
AAGAGAGTTTATGCGGAGAAAAAGTAGATTTAATAATTGATAGTATAGGCTCAGCAACATTCTTAAAATATTTTGATGTA
TTGAAACCAAATGGGAGAATTGTTAATTTTGGTGCAAGTTCAGGAGATAAAATAGAATTGCCTTTAAGGGCGTTATTTTA
TAACCAAATTGATATTATGGGAACATCTATGGGTAGCCGTGAGGAATTTAATGAAATGATTAGGTTTATAGAGAAATATA
AGATTAAACCAATTATAGATAAAGTTTATTCGTTGGAAGAAGCAATTCAAGCGTTGAGCCGTATGGAGCAGGGAGAACAG
TTCGGTAATATCGCTCTACGTATGGAATAA

Upstream 100 bases:

>100_bases
TTTCTTTTGTCATATACATTATTTCTAATTATTGGAGACAGATTAGTTTATTTATTTCGATATTTCTAGTACATTGAAAA
TATTAAGGGGGAATTAAACA

Downstream 100 bases:

>100_bases
AAATATGATTTAATAACCTATGTTTTTATATGTATATGTTATGTAATATATACACTTTTAGTTAGTGGATTATATAATTT
TAAAGGTTTTTCCATCATAT

Product: alcohol dehydrogenase, zinc-containing

Products: aldehyde; ketone; NADH; H+

Alternate protein names: NA

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MKAIVHQYKKGVEGLQYKFSSETHPNAGEVKVKLKAAGLNHRDLFIINNRKEMDLPLVIGSDGAGIVTEIGEGVSADLLQ
AEVIINPSIGWENIAEVPELPEVLGGPKDGTFAEYVIVPAENVVEKPSYLTWEESGVLALSALTAYRALFTKGRLKCGEH
VLIPGIGGGVATFAMLFAKAIGAKVSVTSRVENKRKFAETYGADSSFNSSGNWEESLCGEKVDLIIDSIGSATFLKYFDV
LKPNGRIVNFGASSGDKIELPLRALFYNQIDIMGTSMGSREEFNEMIRFIEKYKIKPIIDKVYSLEEAIQALSRMEQGEQ
FGNIALRME

Sequences:

>Translated_329_residues
MKAIVHQYKKGVEGLQYKFSSETHPNAGEVKVKLKAAGLNHRDLFIINNRKEMDLPLVIGSDGAGIVTEIGEGVSADLLQ
AEVIINPSIGWENIAEVPELPEVLGGPKDGTFAEYVIVPAENVVEKPSYLTWEESGVLALSALTAYRALFTKGRLKCGEH
VLIPGIGGGVATFAMLFAKAIGAKVSVTSRVENKRKFAETYGADSSFNSSGNWEESLCGEKVDLIIDSIGSATFLKYFDV
LKPNGRIVNFGASSGDKIELPLRALFYNQIDIMGTSMGSREEFNEMIRFIEKYKIKPIIDKVYSLEEAIQALSRMEQGEQ
FGNIALRME
>Mature_329_residues
MKAIVHQYKKGVEGLQYKFSSETHPNAGEVKVKLKAAGLNHRDLFIINNRKEMDLPLVIGSDGAGIVTEIGEGVSADLLQ
AEVIINPSIGWENIAEVPELPEVLGGPKDGTFAEYVIVPAENVVEKPSYLTWEESGVLALSALTAYRALFTKGRLKCGEH
VLIPGIGGGVATFAMLFAKAIGAKVSVTSRVENKRKFAETYGADSSFNSSGNWEESLCGEKVDLIIDSIGSATFLKYFDV
LKPNGRIVNFGASSGDKIELPLRALFYNQIDIMGTSMGSREEFNEMIRFIEKYKIKPIIDKVYSLEEAIQALSRMEQGEQ
FGNIALRME

Specific function: Not Known; Probable Catabolic Enzyme. [C]

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI22538446, Length=351, Percent_Identity=27.0655270655271, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI22538444, Length=351, Percent_Identity=27.0655270655271, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI194239674, Length=308, Percent_Identity=27.2727272727273, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI13236495, Length=308, Percent_Identity=27.2727272727273, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI18379349, Length=344, Percent_Identity=25.8720930232558, Blast_Score=92, Evalue=9e-19,
Organism=Homo sapiens, GI24308257, Length=364, Percent_Identity=24.1758241758242, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI47519420, Length=349, Percent_Identity=26.647564469914, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI194239676, Length=303, Percent_Identity=25.0825082508251, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI28557745, Length=243, Percent_Identity=29.2181069958848, Blast_Score=72, Evalue=8e-13,
Organism=Escherichia coli, GI1787863, Length=314, Percent_Identity=27.3885350318471, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1790485, Length=336, Percent_Identity=27.0833333333333, Blast_Score=75, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI71988145, Length=309, Percent_Identity=23.9482200647249, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17507255, Length=293, Percent_Identity=26.962457337884, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17562878, Length=339, Percent_Identity=23.598820058997, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17562876, Length=342, Percent_Identity=21.9298245614035, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6319621, Length=338, Percent_Identity=25.4437869822485, Blast_Score=83, Evalue=6e-17,
Organism=Saccharomyces cerevisiae, GI6323729, Length=325, Percent_Identity=24.3076923076923, Blast_Score=78, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6324486, Length=325, Percent_Identity=24.6153846153846, Blast_Score=77, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6323961, Length=325, Percent_Identity=23.6923076923077, Blast_Score=74, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6323980, Length=320, Percent_Identity=25.3125, Blast_Score=64, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6323099, Length=316, Percent_Identity=23.1012658227848, Blast_Score=63, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: 1.1.1.1

Molecular weight: Translated: 36034; Mature: 36034

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAIVHQYKKGVEGLQYKFSSETHPNAGEVKVKLKAAGLNHRDLFIINNRKEMDLPLVIG
CCHHHHHHHHCCCHHEEEECCCCCCCCCCEEEEEEECCCCCCEEEEECCCCCCCCEEEEC
SDGAGIVTEIGEGVSADLLQAEVIINPSIGWENIAEVPELPEVLGGPKDGTFAEYVIVPA
CCCCCHHHHHCCCCCHHHEEEEEEECCCCCHHHHHHCCCCHHHHCCCCCCCEEEEEEECC
ENVVEKPSYLTWEESGVLALSALTAYRALFTKGRLKCGEHVLIPGIGGGVATFAMLFAKA
HHHHCCCCCEEECCCCEEHHHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHHH
IGAKVSVTSRVENKRKFAETYGADSSFNSSGNWEESLCGEKVDLIIDSIGSATFLKYFDV
HCCCEEEHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCHHHHHHHHCCCHHHHHHHHH
LKPNGRIVNFGASSGDKIELPLRALFYNQIDIMGTSMGSREEFNEMIRFIEKYKIKPIID
CCCCCCEEEECCCCCCEEECCHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHCCCHHHH
KVYSLEEAIQALSRMEQGEQFGNIALRME
HHHHHHHHHHHHHHHHCCHHHCCEEEEEC
>Mature Secondary Structure
MKAIVHQYKKGVEGLQYKFSSETHPNAGEVKVKLKAAGLNHRDLFIINNRKEMDLPLVIG
CCHHHHHHHHCCCHHEEEECCCCCCCCCCEEEEEEECCCCCCEEEEECCCCCCCCEEEEC
SDGAGIVTEIGEGVSADLLQAEVIINPSIGWENIAEVPELPEVLGGPKDGTFAEYVIVPA
CCCCCHHHHHCCCCCHHHEEEEEEECCCCCHHHHHHCCCCHHHHCCCCCCCEEEEEEECC
ENVVEKPSYLTWEESGVLALSALTAYRALFTKGRLKCGEHVLIPGIGGGVATFAMLFAKA
HHHHCCCCCEEECCCCEEHHHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHHH
IGAKVSVTSRVENKRKFAETYGADSSFNSSGNWEESLCGEKVDLIIDSIGSATFLKYFDV
HCCCEEEHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCHHHHHHHHCCCHHHHHHHHH
LKPNGRIVNFGASSGDKIELPLRALFYNQIDIMGTSMGSREEFNEMIRFIEKYKIKPIID
CCCCCCEEEECCCCCCEEECCHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHCCCHHHH
KVYSLEEAIQALSRMEQGEQFGNIALRME
HHHHHHHHHHHHHHHHCCHHHCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: alcohol; NAD+

Specific reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]