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The map label for this gene is yfiS [H]

Identifier: 52142617

GI number: 52142617

Start: 2738690

End: 2739892

Strand: Direct

Name: yfiS [H]

Synonym: BCZK2624

Alternate gene names: 52142617

Gene position: 2738690-2739892 (Clockwise)

Preceding gene: 52142619

Following gene: 52142616

Centisome position: 51.66

GC content: 34.16

Gene sequence:

>1203_bases
ATGTGGCGTAATAAAAATGTTTGGATTGTTTTAATTGGGGAGTTTATTGCTGGTTTAGGGTTATGGCTTGGAATTCTTGG
CAACCTGGAATTTATGCAAAAATATGTCCCTTCTGATTTCATGAAATCAGTTATATTGTTTATCGGCCTATTAGCAGGTG
TTCTAGTGGGACCTATGGCTGGTCGTATCATCGATCAATATGAAAAGAAAAAAGTCCTTCTTTATGCTGGTTTTGGTCGT
GTTATTAGTGTTATTTTTATGTTTTTCGCTATCCAATTTGAAAGTATCGCCTTTATGATTGCATTTATGGTTGCGCTTCA
AATTTCAGCAGCATTTTATTTCCCTGCATTACAATCTGTAATTCCACTCATCGTACGTGAGCATGAGTTATTACAAATGA
ACGGTGTACATATGAATGTAGGTACAATCGCTCGTATTGCAGGTACTTCACTAGGTGGAATTCTTTTAGTTGTAATGAGT
TTACAATATATGTACGCCTTCTCAATGGCAGCATATGCTTTATTATTCCTCTCAACTTTCTTCCTACAATTCGAAGATAA
GAAATCAACAACACCTAGTAAGCAAGCGGCAAAAGATAATAGCTTTATGGAAGTATTTCGTATTTTAAGAGGAATTCCGA
TTGCTTTCACAGCACTTATATTAAGTATTATCCCTCTATTATTTATAGCTGGATTTAATTTAATGGTAATTAATATTAGC
GAAATGCAACATGATCCAACGATTAAAGGCTTTATATATACGATTGAAGGTATCGCATTTATGTTAGGTGCCTTCGTTAT
TAAACGTTTATCTGATCATTTCAAACCTGAAAAGTTACTATATTTCTTCGCTGTTTGTACCGCTTTTGCACATCTATCAT
TGTTCTTTAGCGATATAAAATGGATGTCTCTTACATCATTTGGGTTGTTTGGTTTTAGTGTTGGTTGTTTCTTCCCTATT
ATGTCAACAATTTTCCAAACGAAAGTGGAAAAGAACTATCACGGCCGACTCTTCTCATTCCGTAATATGTTTGAAAGAGT
GATGTTCCAAATTGTCTTACTTGGCACAGGCTTCTTCTTAGATACGATTGGATTGCAATATATGGTTCTTATTTTCGGTG
TTATTTCATTATTCATTATTTTCATATCGCTTTCTAAACAGAAACAGTATGAAAAACAACCATCGCAATCTGCGAATTTA
TAA

Upstream 100 bases:

>100_bases
ATAGACTCTGACTCTAAAAAAGTTCGTTAAAAATAATACATAAAATAAGGAGGTTTTATATACGAGTTTTTCATTTTAAA
AGACGGAGAGGTTTTAGATT

Downstream 100 bases:

>100_bases
CATAAACAAAGAAGCATGGGTCCTATTAGATTAATCCATGCTTCTTTTTTATATAAAACTTTATTTATTACACTTATTGA
AATTATTTAAAGGAGTACCC

Product: macrolide efflux protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 400; Mature: 400

Protein sequence:

>400_residues
MWRNKNVWIVLIGEFIAGLGLWLGILGNLEFMQKYVPSDFMKSVILFIGLLAGVLVGPMAGRIIDQYEKKKVLLYAGFGR
VISVIFMFFAIQFESIAFMIAFMVALQISAAFYFPALQSVIPLIVREHELLQMNGVHMNVGTIARIAGTSLGGILLVVMS
LQYMYAFSMAAYALLFLSTFFLQFEDKKSTTPSKQAAKDNSFMEVFRILRGIPIAFTALILSIIPLLFIAGFNLMVINIS
EMQHDPTIKGFIYTIEGIAFMLGAFVIKRLSDHFKPEKLLYFFAVCTAFAHLSLFFSDIKWMSLTSFGLFGFSVGCFFPI
MSTIFQTKVEKNYHGRLFSFRNMFERVMFQIVLLGTGFFLDTIGLQYMVLIFGVISLFIIFISLSKQKQYEKQPSQSANL

Sequences:

>Translated_400_residues
MWRNKNVWIVLIGEFIAGLGLWLGILGNLEFMQKYVPSDFMKSVILFIGLLAGVLVGPMAGRIIDQYEKKKVLLYAGFGR
VISVIFMFFAIQFESIAFMIAFMVALQISAAFYFPALQSVIPLIVREHELLQMNGVHMNVGTIARIAGTSLGGILLVVMS
LQYMYAFSMAAYALLFLSTFFLQFEDKKSTTPSKQAAKDNSFMEVFRILRGIPIAFTALILSIIPLLFIAGFNLMVINIS
EMQHDPTIKGFIYTIEGIAFMLGAFVIKRLSDHFKPEKLLYFFAVCTAFAHLSLFFSDIKWMSLTSFGLFGFSVGCFFPI
MSTIFQTKVEKNYHGRLFSFRNMFERVMFQIVLLGTGFFLDTIGLQYMVLIFGVISLFIIFISLSKQKQYEKQPSQSANL
>Mature_400_residues
MWRNKNVWIVLIGEFIAGLGLWLGILGNLEFMQKYVPSDFMKSVILFIGLLAGVLVGPMAGRIIDQYEKKKVLLYAGFGR
VISVIFMFFAIQFESIAFMIAFMVALQISAAFYFPALQSVIPLIVREHELLQMNGVHMNVGTIARIAGTSLGGILLVVMS
LQYMYAFSMAAYALLFLSTFFLQFEDKKSTTPSKQAAKDNSFMEVFRILRGIPIAFTALILSIIPLLFIAGFNLMVINIS
EMQHDPTIKGFIYTIEGIAFMLGAFVIKRLSDHFKPEKLLYFFAVCTAFAHLSLFFSDIKWMSLTSFGLFGFSVGCFFPI
MSTIFQTKVEKNYHGRLFSFRNMFERVMFQIVLLGTGFFLDTIGLQYMVLIFGVISLFIIFISLSKQKQYEKQPSQSANL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. TCR/tet family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 45308; Mature: 45308

Theoretical pI: Translated: 9.83; Mature: 9.83

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWRNKNVWIVLIGEFIAGLGLWLGILGNLEFMQKYVPSDFMKSVILFIGLLAGVLVGPMA
CCCCCCEEEEEHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
GRIIDQYEKKKVLLYAGFGRVISVIFMFFAIQFESIAFMIAFMVALQISAAFYFPALQSV
HHHHHHHCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IPLIVREHELLQMNGVHMNVGTIARIAGTSLGGILLVVMSLQYMYAFSMAAYALLFLSTF
HHHHHHHHHHHHHCCCEECHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLQFEDKKSTTPSKQAAKDNSFMEVFRILRGIPIAFTALILSIIPLLFIAGFNLMVINIS
HHHCCCCCCCCCCHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCEEEEEHH
EMQHDPTIKGFIYTIEGIAFMLGAFVIKRLSDHFKPEKLLYFFAVCTAFAHLSLFFSDIK
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
WMSLTSFGLFGFSVGCFFPIMSTIFQTKVEKNYHGRLFSFRNMFERVMFQIVLLGTGFFL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
DTIGLQYMVLIFGVISLFIIFISLSKQKQYEKQPSQSANL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MWRNKNVWIVLIGEFIAGLGLWLGILGNLEFMQKYVPSDFMKSVILFIGLLAGVLVGPMA
CCCCCCEEEEEHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
GRIIDQYEKKKVLLYAGFGRVISVIFMFFAIQFESIAFMIAFMVALQISAAFYFPALQSV
HHHHHHHCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IPLIVREHELLQMNGVHMNVGTIARIAGTSLGGILLVVMSLQYMYAFSMAAYALLFLSTF
HHHHHHHHHHHHHCCCEECHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLQFEDKKSTTPSKQAAKDNSFMEVFRILRGIPIAFTALILSIIPLLFIAGFNLMVINIS
HHHCCCCCCCCCCHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCEEEEEHH
EMQHDPTIKGFIYTIEGIAFMLGAFVIKRLSDHFKPEKLLYFFAVCTAFAHLSLFFSDIK
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
WMSLTSFGLFGFSVGCFFPIMSTIFQTKVEKNYHGRLFSFRNMFERVMFQIVLLGTGFFL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
DTIGLQYMVLIFGVISLFIIFISLSKQKQYEKQPSQSANL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8946165; 9384377 [H]