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The map label for this gene is salK [H]

Identifier: 52142348

GI number: 52142348

Start: 3022879

End: 3024468

Strand: Direct

Name: salK [H]

Synonym: BCZK2894

Alternate gene names: 52142348

Gene position: 3022879-3024468 (Clockwise)

Preceding gene: 52142349

Following gene: 52142347

Centisome position: 57.03

GC content: 26.73

Gene sequence:

>1590_bases
ATGAAAAAGTACTATGAGCAAAAACAAATTTTAATTTTAATTAACCAACTTTGTATGATTATTTTTCTATGCTACGAATT
TTCAATAGACAATATTATAGGAACAGCAAAATTACTCCCTTTACTGCTTATAACGGTCATGTCCATTTATGGATCATATA
TTAGTTTTATCAACTTAAAAAACAATACTCTATTATCACAGTTTTCTAGTTTACTACTTTTTACTTCTTGGCAGTTTTTA
CTTACACTGAACGATGAACCAATTTTTCGTGCATTCAGTACACTACTAAGTGTATTCATTCTATATAAAATTGTGCAATT
TATACTCCTATTCTTTTTCCAAGATTCTATTTATAGTTATAAAAAAGAAAAAGATTGGATTTTACGAGTTACATGTTTAC
TTACATTAGGTGCATATTTAATAAACGATAGAATATTTTCTGTTCTATTTTCATTTCAATGGCTTATCAGTGTTAGTTGG
ATTATTTTTCTATTCCTGAAACATAACAAACGAATTAAATTTGTTTTTAAAAGTGAAAAAAAGCATTTACTTACATCTAC
TGCAATTCTTATCTTCCCCTTTATCGTATATGTTACGTTATTTGGGAAGAGTCCCGAATATGTAAATAATTTAGGATGGT
ACACAATAATTCTGTTCCCCCTATTTAGTATTCATGCAATAGCTTTTAAAAATCATATATCTATGAAACAATATTTCCAC
TTAAAAAAAAGTGCAATTGCTTTTATGTTTGTATGCATTTTTATTTTTATGAGTTCACTTGGAGTACTATTTCAATTTAA
TATGATTACTTATTTCATTTTTATACATACAATTATTTGGTTCGTTCAGCTTTATTTCACATTATTATTTCAAGACACAA
AAAACACTATCTCCAATTTGAATACAAAAAAATTAAAAACTTTGCCAGACAGTTCGTATGTTCATAGCTTAGTACAAATC
GTAAAAGAAGAACAATTAAAAAGTGGATTTTCTAATTATTTACATGATGAAATACTACAAGACATATTAGCTGTTAAAAA
TATGATGAACAAATCTAACAAAAAACAAATTCATGATATGATCGTAGCGACACTGGATAACTTAAGTCATACAATACGCA
TTGAAATGCAAGAGTATCATCCAACTCTATTAAAAACACTTACATTAAAAGAAAATTATCGTAATTTACTTAAAATGATA
CAAAAAAAATATGAAACGAAACATGTTAATATATCCTTTACGTGTAACGACGACTTGTTTTTAGTAGAACCTTATCACCT
TGTCGTATATCGAATATTAAAAGAACTAGTAACAAATGCATTCAAACATTCAAATTGTTCAAAGTTACATTTACATTTAG
TACAAGAAGATGGGGAAATAAAACTTGTTGTGAAAGATAATGGCAAAGGTTTAACAACTACCGAAGCAGATATTTTGAAT
GGTCATAAAGGATTGAATTCGATTAAAGAACAGCTATTTTTATTAAATGGTAAAATGACCATTTCAAATAGTAACCCTTC
TGGTTTATGCATTACTATTATCATTCCTATGAAAGGAGACGATTCCTATAAACATTTTATTAATAGATGA

Upstream 100 bases:

>100_bases
AATTATATTTAACAATAAAAAGTAAAAAACTATAAATAAAGCTGATGATAAAAAAACATCAGCTTTATCTGTATGTAATC
TAACAAAGGTAAGTGATTTT

Downstream 100 bases:

>100_bases
TCATGCTTTGTTTGCAAAAAGCTTGGAAATAGCCTTAGAAGATTATCCTGAAATAGATGAATTCCGTTCATTACAGAATG
TTGAAAATGTCGTTACAATT

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 529; Mature: 529

Protein sequence:

>529_residues
MKKYYEQKQILILINQLCMIIFLCYEFSIDNIIGTAKLLPLLLITVMSIYGSYISFINLKNNTLLSQFSSLLLFTSWQFL
LTLNDEPIFRAFSTLLSVFILYKIVQFILLFFFQDSIYSYKKEKDWILRVTCLLTLGAYLINDRIFSVLFSFQWLISVSW
IIFLFLKHNKRIKFVFKSEKKHLLTSTAILIFPFIVYVTLFGKSPEYVNNLGWYTIILFPLFSIHAIAFKNHISMKQYFH
LKKSAIAFMFVCIFIFMSSLGVLFQFNMITYFIFIHTIIWFVQLYFTLLFQDTKNTISNLNTKKLKTLPDSSYVHSLVQI
VKEEQLKSGFSNYLHDEILQDILAVKNMMNKSNKKQIHDMIVATLDNLSHTIRIEMQEYHPTLLKTLTLKENYRNLLKMI
QKKYETKHVNISFTCNDDLFLVEPYHLVVYRILKELVTNAFKHSNCSKLHLHLVQEDGEIKLVVKDNGKGLTTTEADILN
GHKGLNSIKEQLFLLNGKMTISNSNPSGLCITIIIPMKGDDSYKHFINR

Sequences:

>Translated_529_residues
MKKYYEQKQILILINQLCMIIFLCYEFSIDNIIGTAKLLPLLLITVMSIYGSYISFINLKNNTLLSQFSSLLLFTSWQFL
LTLNDEPIFRAFSTLLSVFILYKIVQFILLFFFQDSIYSYKKEKDWILRVTCLLTLGAYLINDRIFSVLFSFQWLISVSW
IIFLFLKHNKRIKFVFKSEKKHLLTSTAILIFPFIVYVTLFGKSPEYVNNLGWYTIILFPLFSIHAIAFKNHISMKQYFH
LKKSAIAFMFVCIFIFMSSLGVLFQFNMITYFIFIHTIIWFVQLYFTLLFQDTKNTISNLNTKKLKTLPDSSYVHSLVQI
VKEEQLKSGFSNYLHDEILQDILAVKNMMNKSNKKQIHDMIVATLDNLSHTIRIEMQEYHPTLLKTLTLKENYRNLLKMI
QKKYETKHVNISFTCNDDLFLVEPYHLVVYRILKELVTNAFKHSNCSKLHLHLVQEDGEIKLVVKDNGKGLTTTEADILN
GHKGLNSIKEQLFLLNGKMTISNSNPSGLCITIIIPMKGDDSYKHFINR
>Mature_529_residues
MKKYYEQKQILILINQLCMIIFLCYEFSIDNIIGTAKLLPLLLITVMSIYGSYISFINLKNNTLLSQFSSLLLFTSWQFL
LTLNDEPIFRAFSTLLSVFILYKIVQFILLFFFQDSIYSYKKEKDWILRVTCLLTLGAYLINDRIFSVLFSFQWLISVSW
IIFLFLKHNKRIKFVFKSEKKHLLTSTAILIFPFIVYVTLFGKSPEYVNNLGWYTIILFPLFSIHAIAFKNHISMKQYFH
LKKSAIAFMFVCIFIFMSSLGVLFQFNMITYFIFIHTIIWFVQLYFTLLFQDTKNTISNLNTKKLKTLPDSSYVHSLVQI
VKEEQLKSGFSNYLHDEILQDILAVKNMMNKSNKKQIHDMIVATLDNLSHTIRIEMQEYHPTLLKTLTLKENYRNLLKMI
QKKYETKHVNISFTCNDDLFLVEPYHLVVYRILKELVTNAFKHSNCSKLHLHLVQEDGEIKLVVKDNGKGLTTTEADILN
GHKGLNSIKEQLFLLNGKMTISNSNPSGLCITIIIPMKGDDSYKHFINR

Specific function: Sensor in the two-component regulatory system ComP/ComA involved in a major quorum response pathway that regulates the development of genetic competence. Plays a role in sporulation, at least partly interchangeable with that of SpoIIJ. Probably activates

COG id: COG3851

COG function: function code T; Signal transduction histidine kinase, glucose-6-phosphate specific

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011712
- InterPro:   IPR005467 [H]

Pfam domain/function: PF02518 HATPase_c; PF07730 HisKA_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 61997; Mature: 61997

Theoretical pI: Translated: 9.72; Mature: 9.72

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKYYEQKQILILINQLCMIIFLCYEFSIDNIIGTAKLLPLLLITVMSIYGSYISFINLK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECC
NNTLLSQFSSLLLFTSWQFLLTLNDEPIFRAFSTLLSVFILYKIVQFILLFFFQDSIYSY
CCHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KKEKDWILRVTCLLTLGAYLINDRIFSVLFSFQWLISVSWIIFLFLKHNKRIKFVFKSEK
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCC
KHLLTSTAILIFPFIVYVTLFGKSPEYVNNLGWYTIILFPLFSIHAIAFKNHISMKQYFH
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHH
LKKSAIAFMFVCIFIFMSSLGVLFQFNMITYFIFIHTIIWFVQLYFTLLFQDTKNTISNL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NTKKLKTLPDSSYVHSLVQIVKEEQLKSGFSNYLHDEILQDILAVKNMMNKSNKKQIHDM
CHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
IVATLDNLSHTIRIEMQEYHPTLLKTLTLKENYRNLLKMIQKKYETKHVNISFTCNDDLF
HHHHHHCCCEEEEEEEHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCEE
LVEPYHLVVYRILKELVTNAFKHSNCSKLHLHLVQEDGEIKLVVKDNGKGLTTTEADILN
EECHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCEEEEEECCCCCCCCCHHHHHC
GHKGLNSIKEQLFLLNGKMTISNSNPSGLCITIIIPMKGDDSYKHFINR
CCCHHHHHHHHHHHCCCEEEEECCCCCCEEEEEEEEECCCCHHHHHCCC
>Mature Secondary Structure
MKKYYEQKQILILINQLCMIIFLCYEFSIDNIIGTAKLLPLLLITVMSIYGSYISFINLK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECC
NNTLLSQFSSLLLFTSWQFLLTLNDEPIFRAFSTLLSVFILYKIVQFILLFFFQDSIYSY
CCHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KKEKDWILRVTCLLTLGAYLINDRIFSVLFSFQWLISVSWIIFLFLKHNKRIKFVFKSEK
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCC
KHLLTSTAILIFPFIVYVTLFGKSPEYVNNLGWYTIILFPLFSIHAIAFKNHISMKQYFH
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHH
LKKSAIAFMFVCIFIFMSSLGVLFQFNMITYFIFIHTIIWFVQLYFTLLFQDTKNTISNL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NTKKLKTLPDSSYVHSLVQIVKEEQLKSGFSNYLHDEILQDILAVKNMMNKSNKKQIHDM
CHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
IVATLDNLSHTIRIEMQEYHPTLLKTLTLKENYRNLLKMIQKKYETKHVNISFTCNDDLF
HHHHHHCCCEEEEEEEHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCEE
LVEPYHLVVYRILKELVTNAFKHSNCSKLHLHLVQEDGEIKLVVKDNGKGLTTTEADILN
EECHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCEEEEEECCCCCCCCCHHHHHC
GHKGLNSIKEQLFLLNGKMTISNSNPSGLCITIIIPMKGDDSYKHFINR
CCCHHHHHHHHHHHCCCEEEEECCCCCCEEEEEEEEECCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2116363; 9274030; 9384377; 1715859 [H]