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The map label for this gene is fecD [H]

Identifier: 52141753

GI number: 52141753

Start: 3619149

End: 3620156

Strand: Reverse

Name: fecD [H]

Synonym: BCZK3494

Alternate gene names: 52141753

Gene position: 3620156-3619149 (Counterclockwise)

Preceding gene: 52141751

Following gene: 52141754

Centisome position: 68.29

GC content: 37.0

Gene sequence:

>1008_bases
ATGCAGAAAACAAATGCAGTACCAGTAACTATATTATGTATAGCACCCATACTCATCTTATTTACAGTTATACTTTCTAT
TTTGTATGGGGCGAAAAGTATTGATGCTGAAACGGTGTGGAACGCATTATTTCATTTTGATTCAAGCGATGTAAATCATA
ATATTATTATTACTTCACGTTTGCCAAGGGTAGTTGCAGCTCTTTTAGTCGGAGCATTTCTAGCCATATCAGGAGCACTT
ATGCAGGGGATGACAAGAAACTATCTTGCATCCCCTTCTATTATGGGTGTGACGGATGGGGCAGCTTTTGTTATTACACT
TTGTATGATTTTTCTTCCGGGAATGTCATCAATTGGTATGGTTGTATGTTCAATGATTGGTTCTGCACTAGGAGCAGGTA
TCGTGTTTGGTTTTGGTTCACTCCTTCAAAATGGTTTATCGCCAGTTCGGTTAGCGATTATTGGGACAGTTATTGGAACA
TTTTTAAGCAGTGTGTCTGCTGCAATGGCTTCATACTTCCAAATTTCTCAAAATGTTAGTTTTTGGTTTAATGCAAAATT
AGACCAAGTAGACCCTAATATCATTAAAATTACGATACCGTTTGGGATAATTGGAATAGTTTTAGCGCTGTTAATATCAA
AATCTATTACGATTCTTTCTTTAGGAGAAGAAGTTTCTATTAACCTAGGGCAGCGTACAAAACTAGTTAAAGTGATGGCT
ATTTTATCAGTTATCTTTTTAACAGGAACGGCAGTTGCTTTAGTGGGGAAAGTTGGTTTTGTAGGTTTAATTATTCCGCA
CATTACCCGCTTTATAATTGGGGTAGATTATAAGTGGATTTTGCCATGCGCAGGCGTTATTGGCGGCGTTTTTCTAGCGT
TATGTGATATTTTAAGTAGGTTTGTAAACTATCCATTTGAAACACCGATTGGAGTCGTTACCTCCTTAATTGGAATTCCT
TTCTTCCTTTATTTAATCCGTACAAGAGGAGGAGAGAGACATGCTTAA

Upstream 100 bases:

>100_bases
AATGGCACAAGGTGGTACTGCTTGGAGTAAAAAAGCATTCTTAAAAGAAGCAGTGAAAAATTTATCTAAATAATATATTA
AGTAAGGTGCGTTGAATGAT

Downstream 100 bases:

>100_bases
AAGTTCAAGTCAACGTTTTGGAATGGCGATGGGGATTAGTATATTTTTAATACTATGTGCTATTTATATTAGTTTAACGA
ATGGTACGTTTGATATTACG

Product: iron(III) dicitrate transport system permease

Products: ADP; phosphate; ferric enterobactin [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MQKTNAVPVTILCIAPILILFTVILSILYGAKSIDAETVWNALFHFDSSDVNHNIIITSRLPRVVAALLVGAFLAISGAL
MQGMTRNYLASPSIMGVTDGAAFVITLCMIFLPGMSSIGMVVCSMIGSALGAGIVFGFGSLLQNGLSPVRLAIIGTVIGT
FLSSVSAAMASYFQISQNVSFWFNAKLDQVDPNIIKITIPFGIIGIVLALLISKSITILSLGEEVSINLGQRTKLVKVMA
ILSVIFLTGTAVALVGKVGFVGLIIPHITRFIIGVDYKWILPCAGVIGGVFLALCDILSRFVNYPFETPIGVVTSLIGIP
FFLYLIRTRGGERHA

Sequences:

>Translated_335_residues
MQKTNAVPVTILCIAPILILFTVILSILYGAKSIDAETVWNALFHFDSSDVNHNIIITSRLPRVVAALLVGAFLAISGAL
MQGMTRNYLASPSIMGVTDGAAFVITLCMIFLPGMSSIGMVVCSMIGSALGAGIVFGFGSLLQNGLSPVRLAIIGTVIGT
FLSSVSAAMASYFQISQNVSFWFNAKLDQVDPNIIKITIPFGIIGIVLALLISKSITILSLGEEVSINLGQRTKLVKVMA
ILSVIFLTGTAVALVGKVGFVGLIIPHITRFIIGVDYKWILPCAGVIGGVFLALCDILSRFVNYPFETPIGVVTSLIGIP
FFLYLIRTRGGERHA
>Mature_335_residues
MQKTNAVPVTILCIAPILILFTVILSILYGAKSIDAETVWNALFHFDSSDVNHNIIITSRLPRVVAALLVGAFLAISGAL
MQGMTRNYLASPSIMGVTDGAAFVITLCMIFLPGMSSIGMVVCSMIGSALGAGIVFGFGSLLQNGLSPVRLAIIGTVIGT
FLSSVSAAMASYFQISQNVSFWFNAKLDQVDPNIIKITIPFGIIGIVLALLISKSITILSLGEEVSINLGQRTKLVKVMA
ILSVIFLTGTAVALVGKVGFVGLIIPHITRFIIGVDYKWILPCAGVIGGVFLALCDILSRFVNYPFETPIGVVTSLIGIP
FFLYLIRTRGGERHA

Specific function: Part of the ABC transporter complex feuABC/yusV involved in import of the catecholate siderophores bacillibactin and enterobactin (Probable) [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786805, Length=311, Percent_Identity=35.6913183279743, Blast_Score=150, Evalue=9e-38,
Organism=Escherichia coli, GI1790740, Length=298, Percent_Identity=32.2147651006711, Blast_Score=147, Evalue=8e-37,
Organism=Escherichia coli, GI1790741, Length=326, Percent_Identity=27.6073619631902, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1786347, Length=277, Percent_Identity=28.158844765343, Blast_Score=107, Evalue=8e-25,
Organism=Escherichia coli, GI1788004, Length=276, Percent_Identity=32.2463768115942, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1786804, Length=301, Percent_Identity=28.5714285714286, Blast_Score=89, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 35626; Mature: 35626

Theoretical pI: Translated: 9.24; Mature: 9.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKTNAVPVTILCIAPILILFTVILSILYGAKSIDAETVWNALFHFDSSDVNHNIIITSR
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCEEEEECH
LPRVVAALLVGAFLAISGALMQGMTRNYLASPSIMGVTDGAAFVITLCMIFLPGMSSIGM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCHHHHHHHHHHHHHCCCHHHHH
VVCSMIGSALGAGIVFGFGSLLQNGLSPVRLAIIGTVIGTFLSSVSAAMASYFQISQNVS
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
FWFNAKLDQVDPNIIKITIPFGIIGIVLALLISKSITILSLGEEVSINLGQRTKLVKVMA
EEEECCCCCCCCCEEEEEECHHHHHHHHHHHHHCCCEEEECCCCCEECCCHHHHHHHHHH
ILSVIFLTGTAVALVGKVGFVGLIIPHITRFIIGVDYKWILPCAGVIGGVFLALCDILSR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
FVNYPFETPIGVVTSLIGIPFFLYLIRTRGGERHA
HHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MQKTNAVPVTILCIAPILILFTVILSILYGAKSIDAETVWNALFHFDSSDVNHNIIITSR
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCEEEEECH
LPRVVAALLVGAFLAISGALMQGMTRNYLASPSIMGVTDGAAFVITLCMIFLPGMSSIGM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCHHHHHHHHHHHHHCCCHHHHH
VVCSMIGSALGAGIVFGFGSLLQNGLSPVRLAIIGTVIGTFLSSVSAAMASYFQISQNVS
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
FWFNAKLDQVDPNIIKITIPFGIIGIVLALLISKSITILSLGEEVSINLGQRTKLVKVMA
EEEECCCCCCCCCEEEEEECHHHHHHHHHHHHHCCCEEEECCCCCEECCCHHHHHHHHHH
ILSVIFLTGTAVALVGKVGFVGLIIPHITRFIIGVDYKWILPCAGVIGGVFLALCDILSR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
FVNYPFETPIGVVTSLIGIPFFLYLIRTRGGERHA
HHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; ferric enterobactin [Periplasm]; H2O [C]

Specific reaction: ATP + ferric enterobactin [Periplasm] + H2O = ADP + phosphate + ferric enterobactin [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8011666; 9274029; 9384377 [H]