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The map label for this gene is ftsK

Identifier: 52141694

GI number: 52141694

Start: 3686056

End: 3688437

Strand: Reverse

Name: ftsK

Synonym: BCZK3553

Alternate gene names: 52141694

Gene position: 3688437-3686056 (Counterclockwise)

Preceding gene: 52141693

Following gene: 52141695

Centisome position: 69.58

GC content: 37.57

Gene sequence:

>2382_bases
ATGGCAAAACAAAAGCAAAGAGGGACGAAGGCAAAGGCAAGACGTACGATAAAGCCAACTTTGTATTATGAAATCGTCGG
TTTAACTCTTTTTGCACTTTCAATCATTACGATTTTACAGCTAGGCGTTGTAGGGAAATCGTTTGTGTTATTTTTTCGCT
TCTTCTTTGGTGAGTGGTATATAATTGGTGTGTTAGGTGTAATAGCTTTATCAGTTTCATTCGTTATAAAACGTGGATGG
CCGAACCTTTTAAATAAACGGTTAATCGGTTTTTATTTAATAGTATTGGCGATATTAATGTTTAGTCATATTACATTATT
TAACCTTCTTACGAAAGATGGAGCAGTGCAAAATACTTCTGTTATTGTGAGTACGAAGGATAATTTCTTTCTTGAAATGA
AAAAAGGCCCAGATAGCGTTCATTTAGGTGGTGGTATGTTTGGTGCGCTTATGTTTGCGACATGTTACTTCTTATTTGAC
GAAGTAGGAGCTTATATTATTGGTATTATTTTAGTTATTCTCGGTATACTTTGTATAACAAATAAGCATATTGGAGAAGT
CTTAGCTCCAGTTGGTAGAATTCTTAGAAGTCAATTTCAAGTGATGCAAGGGGACTATAAAGATTGGAGAGCAAAAAGAA
CCGCTGAACAAACAGAAAAGAAAAAGACAACAAGAAGCACAAGGAGCAAACGTGCTACAGAACAAGAAGAAATTATTGAG
CCGATGGAAGAAATTTCAATTGACCCTCCGATTATTTCAAATTTCACTGAGAATTATCCAGTAAATGAACAAGAAGATAA
ACGAATTGAAGTAGAGCAAGAAGAGTTAATCACTTCACCGTTTATTGAAGAGGCTCCACCAGTTGAAGAGCCGAAGAAAA
AGCGTGGAGAAAAAATCGTTGAATCGCTAGAGGGTGAAACACAAGCACCTCCTATGCAATTTTCAAATGTAGAAAATAAA
GATTATAAGCTTCCTGCACTTGATATATTGAAGTTTCCAAAGAATAAGCAAGTTACAAATGAAAATGCGGAAATTTATGA
GAATGCTCGTAAATTAGAACGTACGTTCCAAAGCTTTGGAGTGAAAGCGAAAGTAACAAAAGTACATAGAGGTCCTGCAG
TCACAAAATATGAAGTGTATCCTGATATGGGAGTAAAGGTAAGCAAAATCGTCGGTTTAAGTGATGATTTAGCGCTTGCT
TTAGCTGCAAAGGACATTCGTATTGAAGCTCCAATTCCCGGGAAATCAGCTGTAGGGATTGAAGTTCCGAACTCAGAAGT
TTCTATGGTAACACTTAGGGAAGTTCTTGATTCTAAGGCTAATAATCATCCAGAAGAGAAGTTGCTGATTGGTCTTGGAC
GAGATATTACAGGTGAAGCTGTATTAGCTCGCTTAAATAAAATGCCCCATTTACTAGTGGCAGGTGCTACAGGTAGCGGG
AAGAGTGTATGTATTAACGGTATTATTGTTAGTATTTTAATGCGTGCAAAACCACATGAAGTAAAATTAATGATGATTGA
TCCGAAAATGGTAGAGTTAAATGTATATAACGGTGTGCCTCATTTGTTAACACCAGTTGTAACTGATCCGAAAAAAGCAT
CACAGGCATTGAAAAAAGTTGTAAGTGAAATGGAGCGTCGTTATGAGTTATTTGCTCATAGTGGCACGCGAAATATTGAA
GGATATAATGATTATATAAAAGAGCATAATAATCAATCAGAAGCGAAACAACCGGAATTACCTTATATTGTCGTAATTGT
GGACGAGTTAGCAGATTTAATGATGGTTGCTTCGTCGGATGTAGAGGATGCGATTATGCGTCTAGCGCAAATGGCTCGTG
CTGCCGGTATTCATTTAATTATTGCAACGCAACGTCCATCAGTTGATGTAATTACGGGAGTTATTAAAGCGAATATTCCG
TCACGTATTGCATTCGCTGTATCATCTCAAACAGATTCTCGTACAATTCTTGACGGCGGTGGTGCAGAGAAACTGCTAGG
TCGTGGGGATATGCTATTTATACCAATTGGTGCATCGAAGCCTGTACGTGTACAAGGTGCGTTTTTATCAGATGATGAAG
TTGAGAGAGTTGTAGAATATGTTATTGGTCAGCAAAAAGCGCAATATCAAGAAGATATGATCCCGCAAGATGTTCCTGAT
ACGAAGCAGGAAGTAGAAGATGAATTATATGATGAAGCAGTTCAGCTCGTAGTGGAAATGCAAACAGCCTCTGTTTCTAT
GTTGCAACGTAGGTTTAGAGTTGGTTATACCCGTGCTGCCCGATTAATTGATGCAATGGAAATGAATGGTGTAGTAGGAC
CGTATGAAGGTAGTAAACCACGAGAAGTGCTCATTAATGATGTACAAGAAAAAAGTTCATAA

Upstream 100 bases:

>100_bases
AAAAATAGAAGATATAAAGACCTGAAAAAATAGAGAAAACAAACATATAAGCAGAGTTTTTTAGGAAGTTTTACTTATAT
GTAGAACACGAGGTGAAGAA

Downstream 100 bases:

>100_bases
AAAAAGCCTAATTGTTTTTACAATTAGGCTTTTTTATATGCTGGTTTTGTTATATACTATATTCAGCGTTAAAGAAAGGG
CTTACATTTAAGGCGATTCT

Product: stage III sporulation protein E (DNA translocase SpoIIIE)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 793; Mature: 792

Protein sequence:

>793_residues
MAKQKQRGTKAKARRTIKPTLYYEIVGLTLFALSIITILQLGVVGKSFVLFFRFFFGEWYIIGVLGVIALSVSFVIKRGW
PNLLNKRLIGFYLIVLAILMFSHITLFNLLTKDGAVQNTSVIVSTKDNFFLEMKKGPDSVHLGGGMFGALMFATCYFLFD
EVGAYIIGIILVILGILCITNKHIGEVLAPVGRILRSQFQVMQGDYKDWRAKRTAEQTEKKKTTRSTRSKRATEQEEIIE
PMEEISIDPPIISNFTENYPVNEQEDKRIEVEQEELITSPFIEEAPPVEEPKKKRGEKIVESLEGETQAPPMQFSNVENK
DYKLPALDILKFPKNKQVTNENAEIYENARKLERTFQSFGVKAKVTKVHRGPAVTKYEVYPDMGVKVSKIVGLSDDLALA
LAAKDIRIEAPIPGKSAVGIEVPNSEVSMVTLREVLDSKANNHPEEKLLIGLGRDITGEAVLARLNKMPHLLVAGATGSG
KSVCINGIIVSILMRAKPHEVKLMMIDPKMVELNVYNGVPHLLTPVVTDPKKASQALKKVVSEMERRYELFAHSGTRNIE
GYNDYIKEHNNQSEAKQPELPYIVVIVDELADLMMVASSDVEDAIMRLAQMARAAGIHLIIATQRPSVDVITGVIKANIP
SRIAFAVSSQTDSRTILDGGGAEKLLGRGDMLFIPIGASKPVRVQGAFLSDDEVERVVEYVIGQQKAQYQEDMIPQDVPD
TKQEVEDELYDEAVQLVVEMQTASVSMLQRRFRVGYTRAARLIDAMEMNGVVGPYEGSKPREVLINDVQEKSS

Sequences:

>Translated_793_residues
MAKQKQRGTKAKARRTIKPTLYYEIVGLTLFALSIITILQLGVVGKSFVLFFRFFFGEWYIIGVLGVIALSVSFVIKRGW
PNLLNKRLIGFYLIVLAILMFSHITLFNLLTKDGAVQNTSVIVSTKDNFFLEMKKGPDSVHLGGGMFGALMFATCYFLFD
EVGAYIIGIILVILGILCITNKHIGEVLAPVGRILRSQFQVMQGDYKDWRAKRTAEQTEKKKTTRSTRSKRATEQEEIIE
PMEEISIDPPIISNFTENYPVNEQEDKRIEVEQEELITSPFIEEAPPVEEPKKKRGEKIVESLEGETQAPPMQFSNVENK
DYKLPALDILKFPKNKQVTNENAEIYENARKLERTFQSFGVKAKVTKVHRGPAVTKYEVYPDMGVKVSKIVGLSDDLALA
LAAKDIRIEAPIPGKSAVGIEVPNSEVSMVTLREVLDSKANNHPEEKLLIGLGRDITGEAVLARLNKMPHLLVAGATGSG
KSVCINGIIVSILMRAKPHEVKLMMIDPKMVELNVYNGVPHLLTPVVTDPKKASQALKKVVSEMERRYELFAHSGTRNIE
GYNDYIKEHNNQSEAKQPELPYIVVIVDELADLMMVASSDVEDAIMRLAQMARAAGIHLIIATQRPSVDVITGVIKANIP
SRIAFAVSSQTDSRTILDGGGAEKLLGRGDMLFIPIGASKPVRVQGAFLSDDEVERVVEYVIGQQKAQYQEDMIPQDVPD
TKQEVEDELYDEAVQLVVEMQTASVSMLQRRFRVGYTRAARLIDAMEMNGVVGPYEGSKPREVLINDVQEKSS
>Mature_792_residues
AKQKQRGTKAKARRTIKPTLYYEIVGLTLFALSIITILQLGVVGKSFVLFFRFFFGEWYIIGVLGVIALSVSFVIKRGWP
NLLNKRLIGFYLIVLAILMFSHITLFNLLTKDGAVQNTSVIVSTKDNFFLEMKKGPDSVHLGGGMFGALMFATCYFLFDE
VGAYIIGIILVILGILCITNKHIGEVLAPVGRILRSQFQVMQGDYKDWRAKRTAEQTEKKKTTRSTRSKRATEQEEIIEP
MEEISIDPPIISNFTENYPVNEQEDKRIEVEQEELITSPFIEEAPPVEEPKKKRGEKIVESLEGETQAPPMQFSNVENKD
YKLPALDILKFPKNKQVTNENAEIYENARKLERTFQSFGVKAKVTKVHRGPAVTKYEVYPDMGVKVSKIVGLSDDLALAL
AAKDIRIEAPIPGKSAVGIEVPNSEVSMVTLREVLDSKANNHPEEKLLIGLGRDITGEAVLARLNKMPHLLVAGATGSGK
SVCINGIIVSILMRAKPHEVKLMMIDPKMVELNVYNGVPHLLTPVVTDPKKASQALKKVVSEMERRYELFAHSGTRNIEG
YNDYIKEHNNQSEAKQPELPYIVVIVDELADLMMVASSDVEDAIMRLAQMARAAGIHLIIATQRPSVDVITGVIKANIPS
RIAFAVSSQTDSRTILDGGGAEKLLGRGDMLFIPIGASKPVRVQGAFLSDDEVERVVEYVIGQQKAQYQEDMIPQDVPDT
KQEVEDELYDEAVQLVVEMQTASVSMLQRRFRVGYTRAARLIDAMEMNGVVGPYEGSKPREVLINDVQEKSS

Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FtsK domain

Homologues:

Organism=Escherichia coli, GI1787117, Length=486, Percent_Identity=49.1769547325103, Blast_Score=422, Evalue=1e-119,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FTSK_BACAN (Q81WP2)

Other databases:

- EMBL:   AE016879
- EMBL:   AE017334
- EMBL:   AE017225
- RefSeq:   NP_846174.1
- RefSeq:   YP_020571.1
- RefSeq:   YP_029896.1
- ProteinModelPortal:   Q81WP2
- SMR:   Q81WP2
- EnsemblBacteria:   EBBACT00000009107
- EnsemblBacteria:   EBBACT00000015320
- EnsemblBacteria:   EBBACT00000020518
- GeneID:   1086911
- GeneID:   2814576
- GeneID:   2849860
- GenomeReviews:   AE016879_GR
- GenomeReviews:   AE017225_GR
- GenomeReviews:   AE017334_GR
- KEGG:   ban:BA_3930
- KEGG:   bar:GBAA_3930
- KEGG:   bat:BAS3645
- TIGR:   BA_3930
- TIGR:   GBAA_3930
- GeneTree:   EBGT00050000000196
- HOGENOM:   HBG662140
- OMA:   YEVYPDV
- ProtClustDB:   CLSK873312
- BioCyc:   BANT260799:BAS3645-MONOMER
- BioCyc:   BANT261594:GBAA3930-MONOMER
- InterPro:   IPR003593
- InterPro:   IPR018541
- InterPro:   IPR002543
- SMART:   SM00382
- SMART:   SM00843

Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE

EC number: NA

Molecular weight: Translated: 88357; Mature: 88226

Theoretical pI: Translated: 6.76; Mature: 6.76

Prosite motif: PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x197f9288)-; HASH(0x19659f58)-; HASH(0x199d9b28)-; HASH(0x19b6b278)-; HASH(0x19ad418c)-;

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKQKQRGTKAKARRTIKPTLYYEIVGLTLFALSIITILQLGVVGKSFVLFFRFFFGEWY
CCCCHHCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IIGVLGVIALSVSFVIKRGWPNLLNKRLIGFYLIVLAILMFSHITLFNLLTKDGAVQNTS
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCE
VIVSTKDNFFLEMKKGPDSVHLGGGMFGALMFATCYFLFDEVGAYIIGIILVILGILCIT
EEEEECCCEEEEEECCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NKHIGEVLAPVGRILRSQFQVMQGDYKDWRAKRTAEQTEKKKTTRSTRSKRATEQEEIIE
CHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
PMEEISIDPPIISNFTENYPVNEQEDKRIEVEQEELITSPFIEEAPPVEEPKKKRGEKIV
HHHHCCCCCCHHHCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHH
ESLEGETQAPPMQFSNVENKDYKLPALDILKFPKNKQVTNENAEIYENARKLERTFQSFG
HHHCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCC
VKAKVTKVHRGPAVTKYEVYPDMGVKVSKIVGLSDDLALALAAKDIRIEAPIPGKSAVGI
CEEEEEEEECCCCCEEEEECCCCCCCHHHHCCCCCCHHHEEEEECEEEECCCCCCCEEEE
EVPNSEVSMVTLREVLDSKANNHPEEKLLIGLGRDITGEAVLARLNKMPHLLVAGATGSG
ECCCCCHHHHHHHHHHHHHCCCCCCHHEEEECCCCCCHHHHHHHHHCCCEEEEEECCCCC
KSVCINGIIVSILMRAKPHEVKLMMIDPKMVELNVYNGVPHLLTPVVTDPKKASQALKKV
CHHHHHHHHHHHHHHCCCCEEEEEEECCEEEEEEECCCCHHHHCCCCCCHHHHHHHHHHH
VSEMERRYELFAHSGTRNIEGYNDYIKEHNNQSEAKQPELPYIVVIVDELADLMMVASSD
HHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHCCC
VEDAIMRLAQMARAAGIHLIIATQRPSVDVITGVIKANIPSRIAFAVSSQTDSRTILDGG
HHHHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHCCCCCCEEEEEECCCCCCEEECCC
GAEKLLGRGDMLFIPIGASKPVRVQGAFLSDDEVERVVEYVIGQQKAQYQEDMIPQDVPD
CHHHHHCCCCEEEEEECCCCCEEEEEEECCHHHHHHHHHHHHCCHHHHHHHHCCCCCCCC
TKQEVEDELYDEAVQLVVEMQTASVSMLQRRFRVGYTRAARLIDAMEMNGVVGPYEGSKP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
REVLINDVQEKSS
HHHHHHHHHHCCH
>Mature Secondary Structure 
AKQKQRGTKAKARRTIKPTLYYEIVGLTLFALSIITILQLGVVGKSFVLFFRFFFGEWY
CCCHHCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IIGVLGVIALSVSFVIKRGWPNLLNKRLIGFYLIVLAILMFSHITLFNLLTKDGAVQNTS
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCE
VIVSTKDNFFLEMKKGPDSVHLGGGMFGALMFATCYFLFDEVGAYIIGIILVILGILCIT
EEEEECCCEEEEEECCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NKHIGEVLAPVGRILRSQFQVMQGDYKDWRAKRTAEQTEKKKTTRSTRSKRATEQEEIIE
CHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
PMEEISIDPPIISNFTENYPVNEQEDKRIEVEQEELITSPFIEEAPPVEEPKKKRGEKIV
HHHHCCCCCCHHHCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHH
ESLEGETQAPPMQFSNVENKDYKLPALDILKFPKNKQVTNENAEIYENARKLERTFQSFG
HHHCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCC
VKAKVTKVHRGPAVTKYEVYPDMGVKVSKIVGLSDDLALALAAKDIRIEAPIPGKSAVGI
CEEEEEEEECCCCCEEEEECCCCCCCHHHHCCCCCCHHHEEEEECEEEECCCCCCCEEEE
EVPNSEVSMVTLREVLDSKANNHPEEKLLIGLGRDITGEAVLARLNKMPHLLVAGATGSG
ECCCCCHHHHHHHHHHHHHCCCCCCHHEEEECCCCCCHHHHHHHHHCCCEEEEEECCCCC
KSVCINGIIVSILMRAKPHEVKLMMIDPKMVELNVYNGVPHLLTPVVTDPKKASQALKKV
CHHHHHHHHHHHHHHCCCCEEEEEEECCEEEEEEECCCCHHHHCCCCCCHHHHHHHHHHH
VSEMERRYELFAHSGTRNIEGYNDYIKEHNNQSEAKQPELPYIVVIVDELADLMMVASSD
HHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHCCC
VEDAIMRLAQMARAAGIHLIIATQRPSVDVITGVIKANIPSRIAFAVSSQTDSRTILDGG
HHHHHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHCCCCCCEEEEEECCCCCCEEECCC
GAEKLLGRGDMLFIPIGASKPVRVQGAFLSDDEVERVVEYVIGQQKAQYQEDMIPQDVPD
CHHHHHCCCCEEEEEECCCCCEEEEEEECCHHHHHHHHHHHHCCHHHHHHHHCCCCCCCC
TKQEVEDELYDEAVQLVVEMQTASVSMLQRRFRVGYTRAARLIDAMEMNGVVGPYEGSKP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
REVLINDVQEKSS
HHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12721629