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The map label for this gene is secA

Identifier: 52140377

GI number: 52140377

Start: 4969463

End: 4971970

Strand: Reverse

Name: secA

Synonym: BCZK4883

Alternate gene names: 52140377

Gene position: 4971970-4969463 (Counterclockwise)

Preceding gene: 52140376

Following gene: 52140380

Centisome position: 93.79

GC content: 39.63

Gene sequence:

>2508_bases
ATGATCGGTATTTTAAAAAAGGTGTTTGATGTAAATCAACGCCAAATTAAACGTATGCAGAAAACAGTTGAGCAAATTGA
TGCATTAGAGTCATCTATTAAGCCACTAACTGATGAACAATTAAAAGGGAAGACGCTTGAATTTAAAGAACGTCTAACAA
AAGGTGAAACAGTAGATGATCTACTACCTGAAGCTTTTGCGGTTGTTCGTGAAGCTGCGACTCGTGTTCTTGGAATGCGT
CCGTATGGCGTACAGTTAATGGGTGGTATTGCCTTACATGAAGGGAATATCTCTGAGATGAAAACGGGTGAAGGTAAAAC
GTTAACATCTACGTTACCTGTATATTTAAATGCCTTAACAGGAAAAGGCGTTCACGTCGTTACAGTCAATGAATACTTAG
CACAACGTGATGCGAGCGAAATGGGACAACTTCATGAGTTCCTAGGCTTAACAGTAGGAATTAATTTAAACAGTATGTCA
CGCGAAGAGAAACAAGAGGCTTATGCTGCTGATATTACGTATAGCACAAATAATGAGCTTGGATTCGATTACTTACGTGA
CAACATGGTTTTATATAAAGAGCAGTGCGTTCAACGCCCACTTCACTTTGCTATTATCGATGAAGTCGATTCTATCTTAG
TCGATGAAGCGCGTACGCCACTTATTATTTCTGGACAAGCTCAAAAATCAACAGAGCTGTACATGTTTGCAAATGCATTC
GTTCGTACGTTAGAAAATGAAAAAGATTATTCATTTGATGTGAAGACGAAAAATGTAATGTTAACAGAAGATGGTATTAC
GAAAGCGGAGAAAGCTTTCCATATTGAAAACCTATTTGATTTAAAACATGTAGCGCTTCTTCACCATATTAATCAAGCAC
TTCGTGCGCACGTTGTAATGCACCGTGATACAGATTATGTTGTACAAGAAGGCGAAATCGTAATTGTAGACCAATTTACT
GGTCGTCTTATGAAAGGTCGTCGTTATAGTGAAGGTTTACACCAAGCTATCGAGGCAAAAGAAGGCGTAGAAATTCAAAA
TGAAAGTATGACGCTTGCGACAATTACGTTCCAGAACTACTTCCGTATGTACGAAAAGTTATCTGGTATGACTGGTACAG
CGAAAACAGAGGAAGAGGAATTCCGTAACATTTACAATATGAACGTTATTGTAATTCCAACGAACAAACCGATTATTCGT
GATGACCGTGCGGATTTAATCTTCAAATCAATGGAAGGTAAATTTAATGCTGTTGTTGAGGATATTGTAAATCGTCATAA
GCAAGGGCAACCTGTTCTTGTCGGCACAGTGGCGATTGAAACGTCAGAGCTTATTTCAAAAATGTTAACGCGTAAAGGTG
TACGTCATAACATCTTAAATGCGAAAAACCATGCGCGTGAAGCGGATATCATTGCAGAAGCTGGTATGAAAGGTGCTGTA
ACGATCGCCACGAACATGGCAGGGCGTGGTACTGATATTAAGCTTGGAGACGATATTAAAAACATTGGTTTAGCAGTTAT
CGGTACAGAACGTCACGAAAGTCGTCGTATTGATAATCAGTTACGTGGTCGTGCTGGTCGTCAAGGGGACCCAGGTGTTA
CGCAGTTCTACTTATCAATGGAAGATGAACTAATGCGCCGCTTCGGTTCTGATAATATGAAAGCAATGATGGATCGCCTT
GGTATGGATGATTCTCAGCCAATCGAAAGTAAAATGGTTTCTCGTGCAGTAGAATCTGCGCAAAAACGTGTAGAAGGAAA
TAACTATGATGCACGTAAGCAGTTACTACAATATGATGATGTACTTCGTCAGCAACGTGAAGTTATTTACAAACAGCGTC
AAGAGGTAATGGAGTCTGAGAACTTACGCGGTATTATTGAAGGTATGATGAAATCTACAGTAGAGCGTGCGGTTGCGCTT
CATACACAAGAAGAAATTGAAGAAGATTGGAACATTAAAGGTCTTGTTGACTACTTAAATACAAACCTTCTGCAAGAAGG
AGATGTGAAAGAAGAAGAATTACGTCGCCTTGCTCCAGAGGAAATGAGCGAACCAATTATCGCGAAATTAATAGAGCGTT
ACAATGACAAAGAAAAGCTTATGCCAGAAGAGCAAATGCGTGAGTTCGAAAAAGTTGTTGTATTCCGTGTTGTAGATACG
AAATGGACAGAGCATATCGATGCGATGGATCACCTTCGTGAAGGTATTCATTTACGTGCTTACGGTCAAATTGATCCACT
TCGTGAGTATCAAATGGAAGGATTCGCAATGTTCGAGTCAATGATTGCTTCTATTGAAGAGGAAATTTCTCGTTACATTA
TGAAAGCTGAAATTGAACAAAACTTAGAGCGTCAAGAAGTTGTTCAAGGTGAAGCTGTTCACCCATCTAGCGATGGTGAA
GAAGCGAAGAAAAAGCCAGTTGTAAAAGGTGACCAAGTCGGCCGCAACGATTTATGTAAATGTGGTAGCGGTAAAAAATA
TAAAAACTGCTGTGGTATCGGGAAGTAA

Upstream 100 bases:

>100_bases
GGCATAACATACATTTGATTTTTATAACGACTGATTGTAATAGAGAAAAAGAAAAAACAATCGGAAGTTTTATTTTAATA
AAAAGAGGAGCGTATTTCCT

Downstream 100 bases:

>100_bases
TACAGGGCGCTAGCTTTGGCTACTTTGCAAACTTTTACATCAAAAATGTATAATTAAGAAGGATTAAACTCTCTCCGTCA
TAAGTGGAGAGAGTTTCCCT

Product: preprotein translocase subunit SecA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 835; Mature: 835

Protein sequence:

>835_residues
MIGILKKVFDVNQRQIKRMQKTVEQIDALESSIKPLTDEQLKGKTLEFKERLTKGETVDDLLPEAFAVVREAATRVLGMR
PYGVQLMGGIALHEGNISEMKTGEGKTLTSTLPVYLNALTGKGVHVVTVNEYLAQRDASEMGQLHEFLGLTVGINLNSMS
REEKQEAYAADITYSTNNELGFDYLRDNMVLYKEQCVQRPLHFAIIDEVDSILVDEARTPLIISGQAQKSTELYMFANAF
VRTLENEKDYSFDVKTKNVMLTEDGITKAEKAFHIENLFDLKHVALLHHINQALRAHVVMHRDTDYVVQEGEIVIVDQFT
GRLMKGRRYSEGLHQAIEAKEGVEIQNESMTLATITFQNYFRMYEKLSGMTGTAKTEEEEFRNIYNMNVIVIPTNKPIIR
DDRADLIFKSMEGKFNAVVEDIVNRHKQGQPVLVGTVAIETSELISKMLTRKGVRHNILNAKNHAREADIIAEAGMKGAV
TIATNMAGRGTDIKLGDDIKNIGLAVIGTERHESRRIDNQLRGRAGRQGDPGVTQFYLSMEDELMRRFGSDNMKAMMDRL
GMDDSQPIESKMVSRAVESAQKRVEGNNYDARKQLLQYDDVLRQQREVIYKQRQEVMESENLRGIIEGMMKSTVERAVAL
HTQEEIEEDWNIKGLVDYLNTNLLQEGDVKEEELRRLAPEEMSEPIIAKLIERYNDKEKLMPEEQMREFEKVVVFRVVDT
KWTEHIDAMDHLREGIHLRAYGQIDPLREYQMEGFAMFESMIASIEEEISRYIMKAEIEQNLERQEVVQGEAVHPSSDGE
EAKKKPVVKGDQVGRNDLCKCGSGKKYKNCCGIGK

Sequences:

>Translated_835_residues
MIGILKKVFDVNQRQIKRMQKTVEQIDALESSIKPLTDEQLKGKTLEFKERLTKGETVDDLLPEAFAVVREAATRVLGMR
PYGVQLMGGIALHEGNISEMKTGEGKTLTSTLPVYLNALTGKGVHVVTVNEYLAQRDASEMGQLHEFLGLTVGINLNSMS
REEKQEAYAADITYSTNNELGFDYLRDNMVLYKEQCVQRPLHFAIIDEVDSILVDEARTPLIISGQAQKSTELYMFANAF
VRTLENEKDYSFDVKTKNVMLTEDGITKAEKAFHIENLFDLKHVALLHHINQALRAHVVMHRDTDYVVQEGEIVIVDQFT
GRLMKGRRYSEGLHQAIEAKEGVEIQNESMTLATITFQNYFRMYEKLSGMTGTAKTEEEEFRNIYNMNVIVIPTNKPIIR
DDRADLIFKSMEGKFNAVVEDIVNRHKQGQPVLVGTVAIETSELISKMLTRKGVRHNILNAKNHAREADIIAEAGMKGAV
TIATNMAGRGTDIKLGDDIKNIGLAVIGTERHESRRIDNQLRGRAGRQGDPGVTQFYLSMEDELMRRFGSDNMKAMMDRL
GMDDSQPIESKMVSRAVESAQKRVEGNNYDARKQLLQYDDVLRQQREVIYKQRQEVMESENLRGIIEGMMKSTVERAVAL
HTQEEIEEDWNIKGLVDYLNTNLLQEGDVKEEELRRLAPEEMSEPIIAKLIERYNDKEKLMPEEQMREFEKVVVFRVVDT
KWTEHIDAMDHLREGIHLRAYGQIDPLREYQMEGFAMFESMIASIEEEISRYIMKAEIEQNLERQEVVQGEAVHPSSDGE
EAKKKPVVKGDQVGRNDLCKCGSGKKYKNCCGIGK
>Mature_835_residues
MIGILKKVFDVNQRQIKRMQKTVEQIDALESSIKPLTDEQLKGKTLEFKERLTKGETVDDLLPEAFAVVREAATRVLGMR
PYGVQLMGGIALHEGNISEMKTGEGKTLTSTLPVYLNALTGKGVHVVTVNEYLAQRDASEMGQLHEFLGLTVGINLNSMS
REEKQEAYAADITYSTNNELGFDYLRDNMVLYKEQCVQRPLHFAIIDEVDSILVDEARTPLIISGQAQKSTELYMFANAF
VRTLENEKDYSFDVKTKNVMLTEDGITKAEKAFHIENLFDLKHVALLHHINQALRAHVVMHRDTDYVVQEGEIVIVDQFT
GRLMKGRRYSEGLHQAIEAKEGVEIQNESMTLATITFQNYFRMYEKLSGMTGTAKTEEEEFRNIYNMNVIVIPTNKPIIR
DDRADLIFKSMEGKFNAVVEDIVNRHKQGQPVLVGTVAIETSELISKMLTRKGVRHNILNAKNHAREADIIAEAGMKGAV
TIATNMAGRGTDIKLGDDIKNIGLAVIGTERHESRRIDNQLRGRAGRQGDPGVTQFYLSMEDELMRRFGSDNMKAMMDRL
GMDDSQPIESKMVSRAVESAQKRVEGNNYDARKQLLQYDDVLRQQREVIYKQRQEVMESENLRGIIEGMMKSTVERAVAL
HTQEEIEEDWNIKGLVDYLNTNLLQEGDVKEEELRRLAPEEMSEPIIAKLIERYNDKEKLMPEEQMREFEKVVVFRVVDT
KWTEHIDAMDHLREGIHLRAYGQIDPLREYQMEGFAMFESMIASIEEEISRYIMKAEIEQNLERQEVVQGEAVHPSSDGE
EAKKKPVVKGDQVGRNDLCKCGSGKKYKNCCGIGK

Specific function: Part of the Sec protein translocase complex. Interacts with the secYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular mo

COG id: COG0653

COG function: function code U; Preprotein translocase subunit SecA (ATPase, RNA helicase)

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm (By similarity). Note=Distribution is 50-50 (By similarity)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secA family

Homologues:

Organism=Escherichia coli, GI1786287, Length=903, Percent_Identity=50.8305647840532, Blast_Score=871, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SECA1_BACAH (A0RKX7)

Other databases:

- EMBL:   CP000485
- RefSeq:   YP_897377.1
- ProteinModelPortal:   A0RKX7
- SMR:   A0RKX7
- STRING:   A0RKX7
- EnsemblBacteria:   EBBACT00000069149
- GeneID:   4542436
- GenomeReviews:   CP000485_GR
- KEGG:   btl:BALH_4684
- eggNOG:   COG0653
- GeneTree:   EBGT00050000002757
- HOGENOM:   HBG284200
- OMA:   GGMVLHD
- ProtClustDB:   PRK12904
- BioCyc:   BTHU412694:BALH_4684-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01382
- InterPro:   IPR001650
- InterPro:   IPR004027
- InterPro:   IPR000185
- InterPro:   IPR020937
- InterPro:   IPR011115
- InterPro:   IPR014018
- InterPro:   IPR011130
- InterPro:   IPR011116
- Gene3D:   G3DSA:1.10.3060.10
- PRINTS:   PR00906
- SMART:   SM00957
- SMART:   SM00958
- TIGRFAMs:   TIGR00963

Pfam domain/function: PF00271 Helicase_C; PF02810 SEC-C; PF07517 SecA_DEAD; PF01043 SecA_PP_bind; PF07516 SecA_SW; SSF81767 SecA_PP_bd; SSF81886 SecA_SW

EC number: NA

Molecular weight: Translated: 95051; Mature: 95051

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: PS01312 SECA; PS51196 SECA_MOTOR_DEAD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGILKKVFDVNQRQIKRMQKTVEQIDALESSIKPLTDEQLKGKTLEFKERLTKGETVDD
CCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCHHHHHHHCCCCCHHH
LLPEAFAVVREAATRVLGMRPYGVQLMGGIALHEGNISEMKTGEGKTLTSTLPVYLNALT
HHHHHHHHHHHHHHHHHCCCCCCHHEECCEEEECCCHHHCCCCCCCEEHHHHHHHHHHCC
GKGVHVVTVNEYLAQRDASEMGQLHEFLGLTVGINLNSMSREEKQEAYAADITYSTNNEL
CCCEEEEEHHHHHHHCCHHHHHHHHHHHCEEEEECCCCCCHHHHHHHHHEEEEECCCCCC
GFDYLRDNMVLYKEQCVQRPLHFAIIDEVDSILVDEARTPLIISGQAQKSTELYMFANAF
CHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHH
VRTLENEKDYSFDVKTKNVMLTEDGITKAEKAFHIENLFDLKHVALLHHINQALRAHVVM
HHHHCCCCCCEEEEEECEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
HRDTDYVVQEGEIVIVDQFTGRLMKGRRYSEGLHQAIEAKEGVEIQNESMTLATITFQNY
ECCCCCEEECCCEEEEECHHHHHHCCCHHHHHHHHHHHHHCCCEEECCCEEEEEEHHHHH
FRMYEKLSGMTGTAKTEEEEFRNIYNMNVIVIPTNKPIIRDDRADLIFKSMEGKFNAVVE
HHHHHHHCCCCCCCCCCHHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHHHCCHHHHHHH
DIVNRHKQGQPVLVGTVAIETSELISKMLTRKGVRHNILNAKNHAREADIIAEAGMKGAV
HHHHHCCCCCCEEEEEEEECHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHCCCCCEE
TIATNMAGRGTDIKLGDDIKNIGLAVIGTERHESRRIDNQLRGRAGRQGDPGVTQFYLSM
EEEECCCCCCCCEEECCCHHHCCEEEEECCHHHHHHHHHHHHCCCCCCCCCCHHEEEECH
EDELMRRFGSDNMKAMMDRLGMDDSQPIESKMVSRAVESAQKRVEGNNYDARKQLLQYDD
HHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
VLRQQREVIYKQRQEVMESENLRGIIEGMMKSTVERAVALHTQEEIEEDWNIKGLVDYLN
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
TNLLQEGDVKEEELRRLAPEEMSEPIIAKLIERYNDKEKLMPEEQMREFEKVVVFRVVDT
HHHCCCCCCCHHHHHHCCHHHHCCHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHCC
KWTEHIDAMDHLREGIHLRAYGQIDPLREYQMEGFAMFESMIASIEEEISRYIMKAEIEQ
HHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NLERQEVVQGEAVHPSSDGEEAKKKPVVKGDQVGRNDLCKCGSGKKYKNCCGIGK
CCHHHHHHCCCCCCCCCCCHHHHHCCCCCCCCCCCHHHHCCCCCCCHHHHCCCCC
>Mature Secondary Structure
MIGILKKVFDVNQRQIKRMQKTVEQIDALESSIKPLTDEQLKGKTLEFKERLTKGETVDD
CCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCHHHHHHHCCCCCHHH
LLPEAFAVVREAATRVLGMRPYGVQLMGGIALHEGNISEMKTGEGKTLTSTLPVYLNALT
HHHHHHHHHHHHHHHHHCCCCCCHHEECCEEEECCCHHHCCCCCCCEEHHHHHHHHHHCC
GKGVHVVTVNEYLAQRDASEMGQLHEFLGLTVGINLNSMSREEKQEAYAADITYSTNNEL
CCCEEEEEHHHHHHHCCHHHHHHHHHHHCEEEEECCCCCCHHHHHHHHHEEEEECCCCCC
GFDYLRDNMVLYKEQCVQRPLHFAIIDEVDSILVDEARTPLIISGQAQKSTELYMFANAF
CHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHH
VRTLENEKDYSFDVKTKNVMLTEDGITKAEKAFHIENLFDLKHVALLHHINQALRAHVVM
HHHHCCCCCCEEEEEECEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
HRDTDYVVQEGEIVIVDQFTGRLMKGRRYSEGLHQAIEAKEGVEIQNESMTLATITFQNY
ECCCCCEEECCCEEEEECHHHHHHCCCHHHHHHHHHHHHHCCCEEECCCEEEEEEHHHHH
FRMYEKLSGMTGTAKTEEEEFRNIYNMNVIVIPTNKPIIRDDRADLIFKSMEGKFNAVVE
HHHHHHHCCCCCCCCCCHHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHHHCCHHHHHHH
DIVNRHKQGQPVLVGTVAIETSELISKMLTRKGVRHNILNAKNHAREADIIAEAGMKGAV
HHHHHCCCCCCEEEEEEEECHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHCCCCCEE
TIATNMAGRGTDIKLGDDIKNIGLAVIGTERHESRRIDNQLRGRAGRQGDPGVTQFYLSM
EEEECCCCCCCCEEECCCHHHCCEEEEECCHHHHHHHHHHHHCCCCCCCCCCHHEEEECH
EDELMRRFGSDNMKAMMDRLGMDDSQPIESKMVSRAVESAQKRVEGNNYDARKQLLQYDD
HHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
VLRQQREVIYKQRQEVMESENLRGIIEGMMKSTVERAVALHTQEEIEEDWNIKGLVDYLN
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
TNLLQEGDVKEEELRRLAPEEMSEPIIAKLIERYNDKEKLMPEEQMREFEKVVVFRVVDT
HHHCCCCCCCHHHHHHCCHHHHCCHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHCC
KWTEHIDAMDHLREGIHLRAYGQIDPLREYQMEGFAMFESMIASIEEEISRYIMKAEIEQ
HHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NLERQEVVQGEAVHPSSDGEEAKKKPVVKGDQVGRNDLCKCGSGKKYKNCCGIGK
CCHHHHHHCCCCCCCCCCCHHHHHCCCCCCCCCCCHHHHCCCCCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA