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The map label for this gene is lldP [H]

Identifier: 52140339

GI number: 52140339

Start: 5012998

End: 5013321

Strand: Reverse

Name: lldP [H]

Synonym: BCZK4922

Alternate gene names: 52140339

Gene position: 5013321-5012998 (Counterclockwise)

Preceding gene: 52140336

Following gene: 52140340

Centisome position: 94.57

GC content: 39.2

Gene sequence:

>324_bases
TTGCTACAATTTCCAGGATGGATCGGCGTATTCTTAACAGGGTCTGATACGTCAGCAAATGCATTATTCTCAAATTTACA
AGCAATTACAGCACAGCAAGTCGGTGTATCTGAAGTGCTTCTCGTTGCAGCAAATACAACGGGCGGTGTAACAGGTAAAA
TGATTTCTCCGCAATCGATTGCGATTGCTTGTGCAGCAGTTGGACTTGCTGGAAAAGAATCAGATTTATTCCGCTTTACA
GTAAAGCATAGTTTATTCTTCGTAATTATTGTTGGTATTATGACGTATGTACAGGCATATTATTTAACGTGGATGATTCC
ATAA

Upstream 100 bases:

>100_bases
TAATCTGTTAGATTTTTTAAAATGTGGAAGCGATCGCTTACTTGTACAGCTTCTGGGTGTGCTTCGGTTATTGCGTTATG
ATATGTGATAGAACCATCTC

Downstream 100 bases:

>100_bases
AGAGCAAAAGAAATAAACTTTGCATTTTTCAGATTATCGTGTATGATGAGAAAGTATTGAAAATTAAATCAGTGATAAAC
TAGGGGTGCCTAACGTATGC

Product: L-lactate permease, C-terminal fragment

Products: Proton [Cytoplasm]; lactate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 107; Mature: 107

Protein sequence:

>107_residues
MLQFPGWIGVFLTGSDTSANALFSNLQAITAQQVGVSEVLLVAANTTGGVTGKMISPQSIAIACAAVGLAGKESDLFRFT
VKHSLFFVIIVGIMTYVQAYYLTWMIP

Sequences:

>Translated_107_residues
MLQFPGWIGVFLTGSDTSANALFSNLQAITAQQVGVSEVLLVAANTTGGVTGKMISPQSIAIACAAVGLAGKESDLFRFT
VKHSLFFVIIVGIMTYVQAYYLTWMIP
>Mature_107_residues
MLQFPGWIGVFLTGSDTSANALFSNLQAITAQQVGVSEVLLVAANTTGGVTGKMISPQSIAIACAAVGLAGKESDLFRFT
VKHSLFFVIIVGIMTYVQAYYLTWMIP

Specific function: Is the principal permease for the uptake of L-lactate in B.subtilis [H]

COG id: COG1620

COG function: function code C; L-lactate permease

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lactate permease family [H]

Homologues:

Organism=Escherichia coli, GI1790031, Length=104, Percent_Identity=81.7307692307692, Blast_Score=153, Evalue=3e-39,
Organism=Escherichia coli, GI1789347, Length=103, Percent_Identity=69.9029126213592, Blast_Score=151, Evalue=8e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003804 [H]

Pfam domain/function: PF02652 Lactate_perm [H]

EC number: NA

Molecular weight: Translated: 11377; Mature: 11377

Theoretical pI: Translated: 7.34; Mature: 7.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQFPGWIGVFLTGSDTSANALFSNLQAITAQQVGVSEVLLVAANTTGGVTGKMISPQSI
CCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCEECCCHH
AIACAAVGLAGKESDLFRFTVKHSLFFVIIVGIMTYVQAYYLTWMIP
HHHHHHHCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHEECC
>Mature Secondary Structure
MLQFPGWIGVFLTGSDTSANALFSNLQAITAQQVGVSEVLLVAANTTGGVTGKMISPQSI
CCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCEECCCHH
AIACAAVGLAGKESDLFRFTVKHSLFFVIIVGIMTYVQAYYLTWMIP
HHHHHHHCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; lactate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + lactate [Periplasm] = Proton [Cytoplasm] + lactate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377; 8969506 [H]