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The map label for this gene is lytT [H]

Identifier: 52140276

GI number: 52140276

Start: 5086884

End: 5087891

Strand: Reverse

Name: lytT [H]

Synonym: BCZK4985

Alternate gene names: 52140276

Gene position: 5087891-5086884 (Counterclockwise)

Preceding gene: 52140275

Following gene: 52140277

Centisome position: 95.98

GC content: 34.82

Gene sequence:

>1008_bases
ATGGCACTACTGGAGTTGAAACAGTTAGGAAAGACAAATCAGTTACCAGCAGTTGAACTGAAGGTTGAAAAAGGACAATG
TGTTGTTTTGCAATGTAATAACCATACAGCTAAAGTGTTGCACCGCATTATTATTGGTGCAGAAGAAGCTTCAACTGGTA
ATGTACTATTTGAAGGCGAAGCGATTGGAAAGAAAAATTATTCCCGCATCGGTTTTTGTTTTTTGAAAGATGAGGCATAT
GATCGTTTGAAGGTAAAGGAATACTTCAAGTTCTTAATAGGGCTTTATGAATCAAATATGAGTACGGAAGAAGTAGTACA
ATATGTCGGTCTCCTAGATAAATTAAACGTTAAAATAGAAAAACTATCATTTTCAGAGAAACGTCGTCTTCATATTGGAC
GAGTTATGATTCATAATCCGGATTTAGTTATTTTGGAAGAACCAGAGCAAAATGTAGATACAGAGAGTACGATTATGATT
CGAAAAGCGATTATGAAAATGAAAGAGCAAGGAAAGGCAATTTTTATTACGTCATCATTTCTATCGGATGCCCTTTCGTT
AACAGAAGATGTATACATATTAAATAATGATGGTGTGAAAAAAATAGAAATCGAACAAGAAGAAGCAGAAGAAGTCGATG
AAGAAAAAGTCATTCAAATGATTCCGCAAATGAAGTTAGAAAGAATACCAGCGAAAGTGAACGATAAAATCATTTTATTA
GACCCGATGGAAATTCATTTCATTGAAACGCAAAACGGAGTAACACATATTCATGTGCGCGAAGGTGATTTCGTATGTGC
ATTAACATTAAGCGAACTAGAAACGAGATTAACAGGTTTTGGTTTCTTTAGATGCCACCGCTCTTATCTTGTAAATCTAC
AAAGAGTACGAGAAGTGATTACGTGGACTCGTAATAGTTTTAGTTTAATTTTGGATGACGAAAGAAAAAGTTCAATTCCG
CTTTCGAAAGGACGAATGGATGAATTAAAAGGTGTGATTGGGCTATAA

Upstream 100 bases:

>100_bases
TTGGGACGGTCCTTCTTTTTTTATAATGCTTCATAAAATATCTAAATTTTCCATTAATTGTTTGGTATAATAGGATAAAA
AAGTATTTGGGGGAGACGGA

Downstream 100 bases:

>100_bases
AAAGTGCTCCAATAAGCTCAAAATACGATTCATTCACCGGTAAAAATACTCCTTTTACCGGTATTTTACTGCGTAAACCC
TTTGATTTTCATATGATGGA

Product: ABC transporter, ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 335; Mature: 334

Protein sequence:

>335_residues
MALLELKQLGKTNQLPAVELKVEKGQCVVLQCNNHTAKVLHRIIIGAEEASTGNVLFEGEAIGKKNYSRIGFCFLKDEAY
DRLKVKEYFKFLIGLYESNMSTEEVVQYVGLLDKLNVKIEKLSFSEKRRLHIGRVMIHNPDLVILEEPEQNVDTESTIMI
RKAIMKMKEQGKAIFITSSFLSDALSLTEDVYILNNDGVKKIEIEQEEAEEVDEEKVIQMIPQMKLERIPAKVNDKIILL
DPMEIHFIETQNGVTHIHVREGDFVCALTLSELETRLTGFGFFRCHRSYLVNLQRVREVITWTRNSFSLILDDERKSSIP
LSKGRMDELKGVIGL

Sequences:

>Translated_335_residues
MALLELKQLGKTNQLPAVELKVEKGQCVVLQCNNHTAKVLHRIIIGAEEASTGNVLFEGEAIGKKNYSRIGFCFLKDEAY
DRLKVKEYFKFLIGLYESNMSTEEVVQYVGLLDKLNVKIEKLSFSEKRRLHIGRVMIHNPDLVILEEPEQNVDTESTIMI
RKAIMKMKEQGKAIFITSSFLSDALSLTEDVYILNNDGVKKIEIEQEEAEEVDEEKVIQMIPQMKLERIPAKVNDKIILL
DPMEIHFIETQNGVTHIHVREGDFVCALTLSELETRLTGFGFFRCHRSYLVNLQRVREVITWTRNSFSLILDDERKSSIP
LSKGRMDELKGVIGL
>Mature_334_residues
ALLELKQLGKTNQLPAVELKVEKGQCVVLQCNNHTAKVLHRIIIGAEEASTGNVLFEGEAIGKKNYSRIGFCFLKDEAYD
RLKVKEYFKFLIGLYESNMSTEEVVQYVGLLDKLNVKIEKLSFSEKRRLHIGRVMIHNPDLVILEEPEQNVDTESTIMIR
KAIMKMKEQGKAIFITSSFLSDALSLTEDVYILNNDGVKKIEIEQEEAEEVDEEKVIQMIPQMKLERIPAKVNDKIILLD
PMEIHFIETQNGVTHIHVREGDFVCALTLSELETRLTGFGFFRCHRSYLVNLQRVREVITWTRNSFSLILDDERKSSIPL
SKGRMDELKGVIGL

Specific function: Member of the two-component regulatory system lytS/lytT that probably regulates genes involved in cell wall metabolism [H]

COG id: COG3279

COG function: function code KT; Response regulator of the LytR/AlgR family

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788724, Length=191, Percent_Identity=24.0837696335079, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR007492
- InterPro:   IPR001789 [H]

Pfam domain/function: PF04397 LytTR; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 38373; Mature: 38242

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: PS50930 HTH_LYTTR ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALLELKQLGKTNQLPAVELKVEKGQCVVLQCNNHTAKVLHRIIIGAEEASTGNVLFEGE
CCCHHHHHCCCCCCCCEEEEEEECCCEEEEEECCCHHHHHHHHHHCCCCCCCCCEEEECC
AIGKKNYSRIGFCFLKDEAYDRLKVKEYFKFLIGLYESNMSTEEVVQYVGLLDKLNVKIE
CCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEE
KLSFSEKRRLHIGRVMIHNPDLVILEEPEQNVDTESTIMIRKAIMKMKEQGKAIFITSSF
EECCCCCCCEEEEEEEEECCCEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEHHH
LSDALSLTEDVYILNNDGVKKIEIEQEEAEEVDEEKVIQMIPQMKLERIPAKVNDKIILL
HHHHHHHCCCEEEECCCCEEEEEECHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCEEEEE
DPMEIHFIETQNGVTHIHVREGDFVCALTLSELETRLTGFGFFRCHRSYLVNLQRVREVI
CCCEEEEEEECCCEEEEEEECCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TWTRNSFSLILDDERKSSIPLSKGRMDELKGVIGL
HHCCCCEEEEEECCCCCCCCCCCCCHHHHHHHCCC
>Mature Secondary Structure 
ALLELKQLGKTNQLPAVELKVEKGQCVVLQCNNHTAKVLHRIIIGAEEASTGNVLFEGE
CCHHHHHCCCCCCCCEEEEEEECCCEEEEEECCCHHHHHHHHHHCCCCCCCCCEEEECC
AIGKKNYSRIGFCFLKDEAYDRLKVKEYFKFLIGLYESNMSTEEVVQYVGLLDKLNVKIE
CCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEE
KLSFSEKRRLHIGRVMIHNPDLVILEEPEQNVDTESTIMIRKAIMKMKEQGKAIFITSSF
EECCCCCCCEEEEEEEEECCCEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEHHH
LSDALSLTEDVYILNNDGVKKIEIEQEEAEEVDEEKVIQMIPQMKLERIPAKVNDKIILL
HHHHHHHCCCEEEECCCCEEEEEECHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCEEEEE
DPMEIHFIETQNGVTHIHVREGDFVCALTLSELETRLTGFGFFRCHRSYLVNLQRVREVI
CCCEEEEEEECCCEEEEEEECCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TWTRNSFSLILDDERKSSIPLSKGRMDELKGVIGL
HHCCCCEEEEEECCCCCCCCCCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]