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The map label for this gene is murA

Identifier: 52140274

GI number: 52140274

Start: 5089248

End: 5090552

Strand: Reverse

Name: murA

Synonym: BCZK4987

Alternate gene names: 52140274

Gene position: 5090552-5089248 (Counterclockwise)

Preceding gene: 52140273

Following gene: 52140275

Centisome position: 96.03

GC content: 40.46

Gene sequence:

>1305_bases
TTGGAAAAGATCATCGTCCGTGGCGGAAAGCGGTTAAACGGCACAGTGCGTGTTGAGGGCGCAAAAAATGCTGTATTACC
TATAATCGCTGCAGCCCTATTAGCGAGTGATGGAAAGAATGTACTATCTGAAGTACCAGTTTTGTCTGATGTATACACAA
TTAATGAGGTATTACGTCATTTAAATGCTGAAGTCGTATTTGAAAATAACCAAGTAACAATCGATGCTTCTAAAGAGCTA
AACATTGAAGCACCATTTGAATATGTACGTAAAATGCGTGCATCTGTTCAAGTAATGGGACCATTATTAGCACGTAACGG
TCGTGCTCGTATTGCACTTCCTGGTGGATGTGCAATTGGTTCACGTCCAATTGACCAACATTTAAAAGGCTTCGAAGCAA
TGGGAGCAAAAGTACAGGTTGGTAACGGTTTTGTTGAGGCATACGTTGAGGGAGAACTAAAAGGAGCTAAAATTTATTTA
GACTTCCCAAGCGTGGGCGCAACAGAAAACATTATGTCTGCAGCTACATTAGCAAAAGGGACAACAATCCTTGAAAACGC
AGCGAAAGAACCAGAAATCGTTGACTTAGCTAACTTCTTAAATGCGATGGGAGCGAAAGTACGCGGAGCTGGAACGGGAA
CGATTCGTATCGAAGGCGTTGATAAATTATATGGTGCAAACCACTCTATTATTCCTGACCGTATTGAAGCGGGAACATTC
ATGGTTGCAGCAGCAATTACTGGTGGAGACATCTTAATTGAAAATGCTGTACCTGAACATTTACGCTCAATTACAGCGAA
AATGGAAGAAATGGGTGTTAAAATTATCGAAGAAAATGAAGGTGTACGTGTTATCGGCCCAGATAAGTTAAAAGCGGTTG
ATATTAAAACTATGCCTCACCCAGGTTTCCCAACAGACATGCAATCACAAATGATGGCATTATTACTACAAGCTGATGGC
ACAAGTATGATTACAGAAACGGTATTTGAAAACCGCTTTATGCACGTTGAAGAATTCCGTCGTATGAATGCTGATATTAA
AATCGAAGGTCGTTCTGTTATTATGAACGGTCCAAACAGCTTACAAGGTGCTGAAGTAGGCGCAACTGATTTACGTGCTG
CTGCTGCATTAATCTTAGCTGGTTTAGTATCAGAAGGTTACACTCGTGTAACTGAGTTAAAGCATCTTGACCGTGGTTAT
GTAGATTTCCATAAGAAATTAGCTGCATTAGGTGCAACTATTGAACGTGTAAACGAAAAAGTAGAAGAAGTGAAAGAACA
AGAAGTTTCTGATCTTCACGCTTAA

Upstream 100 bases:

>100_bases
TTCTACAGACAACAAAGATACAATTGTGGTTGGCACACCGATCATAACTTCTGAGTATTGAGTGAATAGATACTGAAAAA
AGGACACGGAGGGGAATAAT

Downstream 100 bases:

>100_bases
TTGAAATAGTCTCTACGTCTTTTGACGTAGAGGCTATTTTTTTGGGTTATTACTGTTATAGTCAAGAAATTCTATACTTA
TGCACGTACCAGTAAAAATA

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase 1; UDP-N-acetylglucosamine enolpyruvyl transferase 1; EPT 1

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MEKIIVRGGKRLNGTVRVEGAKNAVLPIIAAALLASDGKNVLSEVPVLSDVYTINEVLRHLNAEVVFENNQVTIDASKEL
NIEAPFEYVRKMRASVQVMGPLLARNGRARIALPGGCAIGSRPIDQHLKGFEAMGAKVQVGNGFVEAYVEGELKGAKIYL
DFPSVGATENIMSAATLAKGTTILENAAKEPEIVDLANFLNAMGAKVRGAGTGTIRIEGVDKLYGANHSIIPDRIEAGTF
MVAAAITGGDILIENAVPEHLRSITAKMEEMGVKIIEENEGVRVIGPDKLKAVDIKTMPHPGFPTDMQSQMMALLLQADG
TSMITETVFENRFMHVEEFRRMNADIKIEGRSVIMNGPNSLQGAEVGATDLRAAAALILAGLVSEGYTRVTELKHLDRGY
VDFHKKLAALGATIERVNEKVEEVKEQEVSDLHA

Sequences:

>Translated_434_residues
MEKIIVRGGKRLNGTVRVEGAKNAVLPIIAAALLASDGKNVLSEVPVLSDVYTINEVLRHLNAEVVFENNQVTIDASKEL
NIEAPFEYVRKMRASVQVMGPLLARNGRARIALPGGCAIGSRPIDQHLKGFEAMGAKVQVGNGFVEAYVEGELKGAKIYL
DFPSVGATENIMSAATLAKGTTILENAAKEPEIVDLANFLNAMGAKVRGAGTGTIRIEGVDKLYGANHSIIPDRIEAGTF
MVAAAITGGDILIENAVPEHLRSITAKMEEMGVKIIEENEGVRVIGPDKLKAVDIKTMPHPGFPTDMQSQMMALLLQADG
TSMITETVFENRFMHVEEFRRMNADIKIEGRSVIMNGPNSLQGAEVGATDLRAAAALILAGLVSEGYTRVTELKHLDRGY
VDFHKKLAALGATIERVNEKVEEVKEQEVSDLHA
>Mature_434_residues
MEKIIVRGGKRLNGTVRVEGAKNAVLPIIAAALLASDGKNVLSEVPVLSDVYTINEVLRHLNAEVVFENNQVTIDASKEL
NIEAPFEYVRKMRASVQVMGPLLARNGRARIALPGGCAIGSRPIDQHLKGFEAMGAKVQVGNGFVEAYVEGELKGAKIYL
DFPSVGATENIMSAATLAKGTTILENAAKEPEIVDLANFLNAMGAKVRGAGTGTIRIEGVDKLYGANHSIIPDRIEAGTF
MVAAAITGGDILIENAVPEHLRSITAKMEEMGVKIIEENEGVRVIGPDKLKAVDIKTMPHPGFPTDMQSQMMALLLQADG
TSMITETVFENRFMHVEEFRRMNADIKIEGRSVIMNGPNSLQGAEVGATDLRAAAALILAGLVSEGYTRVTELKHLDRGY
VDFHKKLAALGATIERVNEKVEEVKEQEVSDLHA

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily

Homologues:

Organism=Escherichia coli, GI1789580, Length=420, Percent_Identity=51.6666666666667, Blast_Score=402, Evalue=1e-113,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURA1_BACAN (Q81K13)

Other databases:

- EMBL:   AE016879
- EMBL:   AE017334
- EMBL:   AE017225
- RefSeq:   NP_847687.1
- RefSeq:   YP_022197.1
- RefSeq:   YP_031376.1
- ProteinModelPortal:   Q81K13
- SMR:   Q81K13
- EnsemblBacteria:   EBBACT00000012725
- EnsemblBacteria:   EBBACT00000018080
- EnsemblBacteria:   EBBACT00000022862
- GeneID:   1085196
- GeneID:   2819064
- GeneID:   2848012
- GenomeReviews:   AE016879_GR
- GenomeReviews:   AE017225_GR
- GenomeReviews:   AE017334_GR
- KEGG:   ban:BA_5529
- KEGG:   bar:GBAA_5529
- KEGG:   bat:BAS5137
- TIGR:   BA_5529
- TIGR:   GBAA_5529
- GeneTree:   EBGT00050000001036
- HOGENOM:   HBG482701
- OMA:   MVKTMRA
- ProtClustDB:   PRK09369
- BioCyc:   BANT260799:BAS5137-MONOMER
- BioCyc:   BANT261594:GBAA5529-MONOMER
- BRENDA:   2.5.1.7
- GO:   GO:0005737
- HAMAP:   MF_00111
- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750
- Gene3D:   G3DSA:3.65.10.10
- PANTHER:   PTHR21090:SF4
- TIGRFAMs:   TIGR01072

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.7

Molecular weight: Translated: 46774; Mature: 46774

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: NA

Important sites: ACT_SITE 117-117

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKIIVRGGKRLNGTVRVEGAKNAVLPIIAAALLASDGKNVLSEVPVLSDVYTINEVLRH
CCCEEEECCCCCCCEEEECCCCCHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHH
LNAEVVFENNQVTIDASKELNIEAPFEYVRKMRASVQVMGPLLARNGRARIALPGGCAIG
CCCEEEEECCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCC
SRPIDQHLKGFEAMGAKVQVGNGFVEAYVEGELKGAKIYLDFPSVGATENIMSAATLAKG
CCCHHHHHHHHHHCCCEEEECCCEEEEEEECCCCCEEEEEECCCCCCHHHHHHHHHHHCC
TTILENAAKEPEIVDLANFLNAMGAKVRGAGTGTIRIEGVDKLYGANHSIIPDRIEAGTF
CHHHHHCCCCCCHHHHHHHHHHHCCEEECCCCCEEEEECCHHHHCCCCCCCCCCCCCCEE
MVAAAITGGDILIENAVPEHLRSITAKMEEMGVKIIEENEGVRVIGPDKLKAVDIKTMPH
EEEEEECCCCEEEECCHHHHHHHHHHHHHHCCCEEEECCCCEEEECCCCEEEEEEEECCC
PGFPTDMQSQMMALLLQADGTSMITETVFENRFMHVEEFRRMNADIKIEGRSVIMNGPNS
CCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHCCCCEEECCCEEEECCCCC
LQGAEVGATDLRAAAALILAGLVSEGYTRVTELKHLDRGYVDFHKKLAALGATIERVNEK
CCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
VEEVKEQEVSDLHA
HHHHHHHHHHHCCC
>Mature Secondary Structure
MEKIIVRGGKRLNGTVRVEGAKNAVLPIIAAALLASDGKNVLSEVPVLSDVYTINEVLRH
CCCEEEECCCCCCCEEEECCCCCHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHH
LNAEVVFENNQVTIDASKELNIEAPFEYVRKMRASVQVMGPLLARNGRARIALPGGCAIG
CCCEEEEECCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCC
SRPIDQHLKGFEAMGAKVQVGNGFVEAYVEGELKGAKIYLDFPSVGATENIMSAATLAKG
CCCHHHHHHHHHHCCCEEEECCCEEEEEEECCCCCEEEEEECCCCCCHHHHHHHHHHHCC
TTILENAAKEPEIVDLANFLNAMGAKVRGAGTGTIRIEGVDKLYGANHSIIPDRIEAGTF
CHHHHHCCCCCCHHHHHHHHHHHCCEEECCCCCEEEEECCHHHHCCCCCCCCCCCCCCEE
MVAAAITGGDILIENAVPEHLRSITAKMEEMGVKIIEENEGVRVIGPDKLKAVDIKTMPH
EEEEEECCCCEEEECCHHHHHHHHHHHHHHCCCEEEECCCCEEEECCCCEEEEEEEECCC
PGFPTDMQSQMMALLLQADGTSMITETVFENRFMHVEEFRRMNADIKIEGRSVIMNGPNS
CCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHCCCCEEECCCEEEECCCCC
LQGAEVGATDLRAAAALILAGLVSEGYTRVTELKHLDRGYVDFHKKLAALGATIERVNEK
CCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
VEEVKEQEVSDLHA
HHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12721629