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The map label for this gene is nuoC [H]

Identifier: 52140264

GI number: 52140264

Start: 5100090

End: 5101319

Strand: Reverse

Name: nuoC [H]

Synonym: BCZK4998

Alternate gene names: 52140264

Gene position: 5101319-5100090 (Counterclockwise)

Preceding gene: 52140262

Following gene: 52140263

Centisome position: 96.23

GC content: 46.67

Gene sequence:

>1230_bases
ATGAGTGATCCTAACAAAGACTTAGAGGATTTAAAAAGAGAAGCGGCTAGGCGTGCGAAAGAAGAGGCAAGAAAGCGTCT
CGTTGCGAAACATGGTGTGGAAATAAGTAAACTTGAGGAAGAAAATCGCGAAAAAGAGAAAGCGCTACCAAAAAATGACG
ATATGACTATAGAAGAAGCAAAACGACGTGCAGCCGCCGCCACAAAAGCGAAAGCAGCGGCGTTAGCGAAGCAGAAAAGA
GAAGGAATAGAAGAAGTAACGGAAGAAGAAAAGGCGAAAGCGAAGGCAGCCGCGGCGGCAAAAGCAAAGGCGGCGGCATT
AGCCAAGCAAAAAAGAGAAGGAACAGAAGAAATAACGGAAGAAGAAAAGGCGAAGGCGAAGGCAGCGGCAGCCGCAAAAG
CAAAAGCGGCGGCGTTAGCGAAGCAGAAAAGAGAAGGAACAGAAGAAGTACCAGAAGAGGAAAAGGCGAAAGCAAAGGCT
AAGGCAGCCGCGGCGGCATTAGCGAAGCAGAAAAGAGAAGGAACAGAGGAAGTAACGGAAGAAGAAAAGGCGAAAGCGAA
GGCAGTCGCAGCCGCGAAAGCAAAAGCAGCGGTGTTAGCGAAGCAGAAAGCATCGCAAGGTAATGGGGATTCGGGAGATG
AAAAGGCGAAGGCAATTGCAGCAGCAAAGGCAAAAGCGGCAGCCGCTGCAAGGGCGAAGACAAAGGGTGCTGAAGGTAAG
AAGGAAGAGGCGCCGAAGCAGGAAGAGTCATCCGTGAATGAGCCGTATTTAAATCAGTATGTTGAAGTTATTAAGGAAAA
GATAGGAGAGGATATATTAGTAGATTCCTACATTAATAAACTGTCAAAAGATGTACCAACTCTTGTGGTGGAACCCGCAA
AATATTATGAAGTAATGGAGTTACTGCGATTCCATGAGGGACTTGCATTTGATTATATGTCAGAGCTACACGCGACAGAT
TTTGTGACACATATGGAAGTGTATGTTCATTTATTTTCATATGGAAAGAAACAGTCAGTAGCGGTGAAGGTGAAGCTGGA
TAGGGAAGCACCGCAAGTGGAATCGGTGACAGCGCTTTGGAAAGGAGCGGACTGGCCAGAGCGGGAAGCGTATGATTTGC
TTGGTATTGTATTTAAGGGGCATCCGAATTTATCACGTATTTTAATGCCTGATGATTGGGTAGGGCACCCGCTTAGGAAA
GATTATGAACCGTATGATGTGGAGGTGTAG

Upstream 100 bases:

>100_bases
CTGGTTGCCCACCAAATCCTGCAGCTTTAATTTATGGAATTAATAAATTAAAAGAAAAAATTCGTTACGAAGCGAAGACT
GGAAAGCAGGTGACGAATAA

Downstream 100 bases:

>100_bases
CTAAATGATCCGTACGGAAGAAATGCTTTTGAATGTAGGTCCTCAGCATCCAAGTACACATGGTGTGTTCAGGCTTGTTA
TTAAGATTGACGGGGAAATT

Product: NADH dehydrogenase subunit C

Products: NA

Alternate protein names: NADH dehydrogenase I subunit C; NDH-1 subunit C [H]

Number of amino acids: Translated: 409; Mature: 408

Protein sequence:

>409_residues
MSDPNKDLEDLKREAARRAKEEARKRLVAKHGVEISKLEEENREKEKALPKNDDMTIEEAKRRAAAATKAKAAALAKQKR
EGIEEVTEEEKAKAKAAAAAKAKAAALAKQKREGTEEITEEEKAKAKAAAAAKAKAAALAKQKREGTEEVPEEEKAKAKA
KAAAAALAKQKREGTEEVTEEEKAKAKAVAAAKAKAAVLAKQKASQGNGDSGDEKAKAIAAAKAKAAAAARAKTKGAEGK
KEEAPKQEESSVNEPYLNQYVEVIKEKIGEDILVDSYINKLSKDVPTLVVEPAKYYEVMELLRFHEGLAFDYMSELHATD
FVTHMEVYVHLFSYGKKQSVAVKVKLDREAPQVESVTALWKGADWPEREAYDLLGIVFKGHPNLSRILMPDDWVGHPLRK
DYEPYDVEV

Sequences:

>Translated_409_residues
MSDPNKDLEDLKREAARRAKEEARKRLVAKHGVEISKLEEENREKEKALPKNDDMTIEEAKRRAAAATKAKAAALAKQKR
EGIEEVTEEEKAKAKAAAAAKAKAAALAKQKREGTEEITEEEKAKAKAAAAAKAKAAALAKQKREGTEEVPEEEKAKAKA
KAAAAALAKQKREGTEEVTEEEKAKAKAVAAAKAKAAVLAKQKASQGNGDSGDEKAKAIAAAKAKAAAAARAKTKGAEGK
KEEAPKQEESSVNEPYLNQYVEVIKEKIGEDILVDSYINKLSKDVPTLVVEPAKYYEVMELLRFHEGLAFDYMSELHATD
FVTHMEVYVHLFSYGKKQSVAVKVKLDREAPQVESVTALWKGADWPEREAYDLLGIVFKGHPNLSRILMPDDWVGHPLRK
DYEPYDVEV
>Mature_408_residues
SDPNKDLEDLKREAARRAKEEARKRLVAKHGVEISKLEEENREKEKALPKNDDMTIEEAKRRAAAATKAKAAALAKQKRE
GIEEVTEEEKAKAKAAAAAKAKAAALAKQKREGTEEITEEEKAKAKAAAAAKAKAAALAKQKREGTEEVPEEEKAKAKAK
AAAAALAKQKREGTEEVTEEEKAKAKAVAAAKAKAAVLAKQKASQGNGDSGDEKAKAIAAAKAKAAAAARAKTKGAEGKK
EEAPKQEESSVNEPYLNQYVEVIKEKIGEDILVDSYINKLSKDVPTLVVEPAKYYEVMELLRFHEGLAFDYMSELHATDF
VTHMEVYVHLFSYGKKQSVAVKVKLDREAPQVESVTALWKGADWPEREAYDLLGIVFKGHPNLSRILMPDDWVGHPLRKD
YEPYDVEV

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translo

COG id: COG0852

COG function: function code C; NADH:ubiquinone oxidoreductase 27 kD subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 30 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI4758788, Length=176, Percent_Identity=28.9772727272727, Blast_Score=78, Evalue=2e-14,
Organism=Escherichia coli, GI145693162, Length=100, Percent_Identity=44, Blast_Score=91, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71990788, Length=118, Percent_Identity=36.4406779661017, Blast_Score=82, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI32563621, Length=118, Percent_Identity=36.4406779661017, Blast_Score=81, Evalue=9e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010218
- InterPro:   IPR001268
- InterPro:   IPR020396
- ProDom:   PD001581 [H]

Pfam domain/function: PF00329 Complex1_30kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 44853; Mature: 44722

Theoretical pI: Translated: 9.11; Mature: 9.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDPNKDLEDLKREAARRAKEEARKRLVAKHGVEISKLEEENREKEKALPKNDDMTIEEA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCHHHH
KRRAAAATKAKAAALAKQKREGIEEVTEEEKAKAKAAAAAKAKAAALAKQKREGTEEITE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
EEKAKAKAAAAAKAKAAALAKQKREGTEEVPEEEKAKAKAKAAAAALAKQKREGTEEVTE
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
EEKAKAKAVAAAKAKAAVLAKQKASQGNGDSGDEKAKAIAAAKAKAAAAARAKTKGAEGK
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
KEEAPKQEESSVNEPYLNQYVEVIKEKIGEDILVDSYINKLSKDVPTLVVEPAKYYEVME
HHCCCCHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEECHHHHHHHHH
LLRFHEGLAFDYMSELHATDFVTHMEVYVHLFSYGKKQSVAVKVKLDREAPQVESVTALW
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHH
KGADWPEREAYDLLGIVFKGHPNLSRILMPDDWVGHPLRKDYEPYDVEV
CCCCCCCHHHHHHHHHHCCCCCCCCEEECCCCCCCCCHHCCCCCCCCCC
>Mature Secondary Structure 
SDPNKDLEDLKREAARRAKEEARKRLVAKHGVEISKLEEENREKEKALPKNDDMTIEEA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCHHHH
KRRAAAATKAKAAALAKQKREGIEEVTEEEKAKAKAAAAAKAKAAALAKQKREGTEEITE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
EEKAKAKAAAAAKAKAAALAKQKREGTEEVPEEEKAKAKAKAAAAALAKQKREGTEEVTE
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
EEKAKAKAVAAAKAKAAVLAKQKASQGNGDSGDEKAKAIAAAKAKAAAAARAKTKGAEGK
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
KEEAPKQEESSVNEPYLNQYVEVIKEKIGEDILVDSYINKLSKDVPTLVVEPAKYYEVME
HHCCCCHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEECHHHHHHHHH
LLRFHEGLAFDYMSELHATDFVTHMEVYVHLFSYGKKQSVAVKVKLDREAPQVESVTALW
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHH
KGADWPEREAYDLLGIVFKGHPNLSRILMPDDWVGHPLRKDYEPYDVEV
CCCCCCCHHHHHHHHHHCCCCCCCCEEECCCCCCCCCHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA