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The map label for this gene is atpA

Identifier: 52140254

GI number: 52140254

Start: 5109972

End: 5111480

Strand: Reverse

Name: atpA

Synonym: BCZK5007

Alternate gene names: 52140254

Gene position: 5111480-5109972 (Counterclockwise)

Preceding gene: 52140252

Following gene: 52140258

Centisome position: 96.43

GC content: 41.95

Gene sequence:

>1509_bases
ATGAGCATCAGAGCTGAAGAAATTAGCGCACTGATAAAGCAACAAATCGAGAACTATCAGTCTGAAATCGAAGTTAGTGA
TGTTGGTACAGTTATCCAAGTTGGTGACGGTATCGCGCGTGCTCATGGTCTTGATAACGTTATGGCTGGTGAACTTGTAG
AGTTCTCTAACGGCGTTATGGGGCTAGCACAAAATTTAGAGGAAAACAACGTAGGTATTATCATTTTAGGACCTTACACA
GAAATCCGTGAAGGCGACGAAGTTCGTCGTACTGGTCGCATCATGCAAGTACCAGTAGGAAAAGAACTAATTGGTCGTGT
TGTAAACCCATTAGGTCAACCAGTTGATGGTTTAGGCCCAATCAATACAACAAACACTCGTCCAATCGAAAGTCCAGCAC
CAGGTGTAATGGATCGTAAATCTGTTCATGAGCCACTTCAAACAGGTATTAAAGCGATCGACGCTCTTGTACCAATTGGC
CGTGGTCAACGTGAGTTAATCATCGGTGACCGTCAAACAGGTAAAACAGCAGTTGCGCTTGATACAATCATTAACCAAAA
AGATGAAGATATGATTTGTATCTACGTAGCAATCGGACAAAAAGAATCAACTGTACGTAACGTAGTAGAAACACTACGTA
AGCATGGTGCATTAGAGTACACAATCGTTGTAACTGCATCTGCTTCTCAACCAGCTCCATTATTATACCTAGCTCCTTAC
GCTGGTGTAACAATGGGTGAAGAGTTCATGTACAATGGTAAACACGTATTAGTAGTATATGATGACTTATCAAAACAAGC
AGCAGCTTACCGTGAGCTGTCATTACTATTACGTCGTCCTCCAGGTCGTGAAGCTTATCCAGGGGATGTATTCTACTTAC
ATTCTCGCTTATTAGAGCGTGCAGCAAAATTAAGTGATGCAAAAGGCGGCGGTTCTTTAACGGCACTACCTTTCATCGAA
ACACAAGCAGGGGACGTATCAGCTTACATCCCAACAAACGTAATCTCGATTACGGATGGACAAATCTTCTTACAATCTGA
CCTATTCTTCTCTGGCGTACGTCCAGCGATCGATGCGGGTACTTCTGTATCTCGTGTAGGTGGATCTGCTCAGATTAAAG
CAATGAGTAAAGTATCAGGTACACTTCGTCTTGACCTTGCATCTTACCGTGAGTTAGAAGCGTTCGCTCAGTTCGGTTCT
GACTTAGATAAAGCAACTCAAGCGAAACTAAACCGCGGTGCTCGTACTGTTGAGGTATTAAAACAAGGATTACACAAACC
GTTACGTGTAGAGAAACAAGTTATCATTCTTTACGCTTTAACACGTGGATTCCTAGATGATATTCCAGTAGTAGATATCA
CTCGTTTCGAAGAAGAATTCCATGCTTGGTTAGATTCTAATGCGACTGACTTATTAGAAGAAATCCGCACAACTAAGAAA
CTTGCGGATGACGACAAATTTGCAGCAGCAATTAACGGATTTAAAAAAGTATTCGTAGCTTCTGAGTAA

Upstream 100 bases:

>100_bases
TTAAAGTACGTATTGGAAATCGCATTTATGACGGAAGTTTACAAGGAAAATTAGCACGTATTCAGCGTGAATTAATGAAG
AATAGATAGGGGTGAAGCAC

Downstream 100 bases:

>100_bases
TAAAAGCGGAAGCGGCTCGTCCTGAATGTGAGGGGGAAGAAGTGAAGCCACCGAGCATTCAAGCCGCTGGAGCTAGATAA
TATATAAAGGCATCTCAATT

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha; F-ATPase subunit alpha

Number of amino acids: Translated: 502; Mature: 501

Protein sequence:

>502_residues
MSIRAEEISALIKQQIENYQSEIEVSDVGTVIQVGDGIARAHGLDNVMAGELVEFSNGVMGLAQNLEENNVGIIILGPYT
EIREGDEVRRTGRIMQVPVGKELIGRVVNPLGQPVDGLGPINTTNTRPIESPAPGVMDRKSVHEPLQTGIKAIDALVPIG
RGQRELIIGDRQTGKTAVALDTIINQKDEDMICIYVAIGQKESTVRNVVETLRKHGALEYTIVVTASASQPAPLLYLAPY
AGVTMGEEFMYNGKHVLVVYDDLSKQAAAYRELSLLLRRPPGREAYPGDVFYLHSRLLERAAKLSDAKGGGSLTALPFIE
TQAGDVSAYIPTNVISITDGQIFLQSDLFFSGVRPAIDAGTSVSRVGGSAQIKAMSKVSGTLRLDLASYRELEAFAQFGS
DLDKATQAKLNRGARTVEVLKQGLHKPLRVEKQVIILYALTRGFLDDIPVVDITRFEEEFHAWLDSNATDLLEEIRTTKK
LADDDKFAAAINGFKKVFVASE

Sequences:

>Translated_502_residues
MSIRAEEISALIKQQIENYQSEIEVSDVGTVIQVGDGIARAHGLDNVMAGELVEFSNGVMGLAQNLEENNVGIIILGPYT
EIREGDEVRRTGRIMQVPVGKELIGRVVNPLGQPVDGLGPINTTNTRPIESPAPGVMDRKSVHEPLQTGIKAIDALVPIG
RGQRELIIGDRQTGKTAVALDTIINQKDEDMICIYVAIGQKESTVRNVVETLRKHGALEYTIVVTASASQPAPLLYLAPY
AGVTMGEEFMYNGKHVLVVYDDLSKQAAAYRELSLLLRRPPGREAYPGDVFYLHSRLLERAAKLSDAKGGGSLTALPFIE
TQAGDVSAYIPTNVISITDGQIFLQSDLFFSGVRPAIDAGTSVSRVGGSAQIKAMSKVSGTLRLDLASYRELEAFAQFGS
DLDKATQAKLNRGARTVEVLKQGLHKPLRVEKQVIILYALTRGFLDDIPVVDITRFEEEFHAWLDSNATDLLEEIRTTKK
LADDDKFAAAINGFKKVFVASE
>Mature_501_residues
SIRAEEISALIKQQIENYQSEIEVSDVGTVIQVGDGIARAHGLDNVMAGELVEFSNGVMGLAQNLEENNVGIIILGPYTE
IREGDEVRRTGRIMQVPVGKELIGRVVNPLGQPVDGLGPINTTNTRPIESPAPGVMDRKSVHEPLQTGIKAIDALVPIGR
GQRELIIGDRQTGKTAVALDTIINQKDEDMICIYVAIGQKESTVRNVVETLRKHGALEYTIVVTASASQPAPLLYLAPYA
GVTMGEEFMYNGKHVLVVYDDLSKQAAAYRELSLLLRRPPGREAYPGDVFYLHSRLLERAAKLSDAKGGGSLTALPFIET
QAGDVSAYIPTNVISITDGQIFLQSDLFFSGVRPAIDAGTSVSRVGGSAQIKAMSKVSGTLRLDLASYRELEAFAQFGSD
LDKATQAKLNRGARTVEVLKQGLHKPLRVEKQVIILYALTRGFLDDIPVVDITRFEEEFHAWLDSNATDLLEEIRTTKKL
ADDDKFAAAINGFKKVFVASE

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family

Homologues:

Organism=Homo sapiens, GI50345984, Length=504, Percent_Identity=59.1269841269841, Blast_Score=598, Evalue=1e-171,
Organism=Homo sapiens, GI4757810, Length=504, Percent_Identity=59.1269841269841, Blast_Score=598, Evalue=1e-171,
Organism=Homo sapiens, GI19913428, Length=307, Percent_Identity=28.3387622149837, Blast_Score=112, Evalue=1e-24,
Organism=Homo sapiens, GI19913426, Length=307, Percent_Identity=28.3387622149837, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI32189394, Length=316, Percent_Identity=26.8987341772152, Blast_Score=103, Evalue=5e-22,
Organism=Homo sapiens, GI19913424, Length=235, Percent_Identity=28.0851063829787, Blast_Score=69, Evalue=9e-12,
Organism=Escherichia coli, GI1790172, Length=508, Percent_Identity=54.3307086614173, Blast_Score=559, Evalue=1e-160,
Organism=Escherichia coli, GI1788251, Length=272, Percent_Identity=33.4558823529412, Blast_Score=122, Evalue=8e-29,
Organism=Escherichia coli, GI1790170, Length=318, Percent_Identity=26.7295597484277, Blast_Score=105, Evalue=9e-24,
Organism=Caenorhabditis elegans, GI71988063, Length=478, Percent_Identity=60.0418410041841, Blast_Score=594, Evalue=1e-170,
Organism=Caenorhabditis elegans, GI71988080, Length=478, Percent_Identity=60.0418410041841, Blast_Score=593, Evalue=1e-170,
Organism=Caenorhabditis elegans, GI71988074, Length=478, Percent_Identity=55.8577405857741, Blast_Score=542, Evalue=1e-154,
Organism=Caenorhabditis elegans, GI17510931, Length=383, Percent_Identity=26.6318537859008, Blast_Score=123, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17570191, Length=298, Percent_Identity=27.5167785234899, Blast_Score=112, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI25144756, Length=316, Percent_Identity=25.3164556962025, Blast_Score=96, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17509265, Length=51, Percent_Identity=60.7843137254902, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71988068, Length=71, Percent_Identity=40.8450704225352, Blast_Score=72, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17565854, Length=235, Percent_Identity=27.6595744680851, Blast_Score=70, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6319370, Length=503, Percent_Identity=57.8528827037773, Blast_Score=591, Evalue=1e-169,
Organism=Saccharomyces cerevisiae, GI6319603, Length=304, Percent_Identity=27.9605263157895, Blast_Score=113, Evalue=7e-26,
Organism=Saccharomyces cerevisiae, GI6322581, Length=415, Percent_Identity=26.9879518072289, Blast_Score=113, Evalue=9e-26,
Organism=Drosophila melanogaster, GI24658560, Length=505, Percent_Identity=58.2178217821782, Blast_Score=590, Evalue=1e-169,
Organism=Drosophila melanogaster, GI281361666, Length=301, Percent_Identity=27.906976744186, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24646341, Length=301, Percent_Identity=27.906976744186, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI17136796, Length=301, Percent_Identity=27.906976744186, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24638766, Length=316, Percent_Identity=26.8987341772152, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI28574560, Length=463, Percent_Identity=25.4859611231102, Blast_Score=93, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24583988, Length=235, Percent_Identity=26.3829787234043, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24583986, Length=235, Percent_Identity=26.3829787234043, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24583984, Length=235, Percent_Identity=26.3829787234043, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24583992, Length=235, Percent_Identity=26.3829787234043, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI20129479, Length=237, Percent_Identity=27.8481012658228, Blast_Score=66, Evalue=5e-11,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ATPA_BACCR (Q814W0)

Other databases:

- EMBL:   AE016877
- RefSeq:   NP_834970.2
- ProteinModelPortal:   Q814W0
- SMR:   Q814W0
- STRING:   Q814W0
- EnsemblBacteria:   EBBACT00000031240
- GeneID:   1207648
- GenomeReviews:   AE016877_GR
- KEGG:   bce:BC5308
- eggNOG:   COG0056
- GeneTree:   EBGT00050000001318
- HOGENOM:   HBG565875
- OMA:   GSDRDIK
- ProtClustDB:   PRK09281
- BioCyc:   BCER226900:BC_5308-MONOMER
- HAMAP:   MF_01346
- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100
- PANTHER:   PTHR15184:SF3
- TIGRFAMs:   TIGR00962

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N; SSF47917 ATPase_a/b_C; SSF50615 ATPase_a/b_N

EC number: =3.6.3.14

Molecular weight: Translated: 54644; Mature: 54513

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIRAEEISALIKQQIENYQSEIEVSDVGTVIQVGDGIARAHGLDNVMAGELVEFSNGVM
CCCCHHHHHHHHHHHHHHHHHHEEHHHCCCEEEECCCHHHHCCCCHHHHHHHHHHCCCHH
GLAQNLEENNVGIIILGPYTEIREGDEVRRTGRIMQVPVGKELIGRVVNPLGQPVDGLGP
HHHHCCCCCCEEEEEECCCHHHHCCHHHHHCCCEEECCCCHHHHHHHHHHCCCCCCCCCC
INTTNTRPIESPAPGVMDRKSVHEPLQTGIKAIDALVPIGRGQRELIIGDRQTGKTAVAL
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHH
DTIINQKDEDMICIYVAIGQKESTVRNVVETLRKHGALEYTIVVTASASQPAPLLYLAPY
HHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCEEEECCC
AGVTMGEEFMYNGKHVLVVYDDLSKQAAAYRELSLLLRRPPGREAYPGDVFYLHSRLLER
CCCCCCHHHEECCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
AAKLSDAKGGGSLTALPFIETQAGDVSAYIPTNVISITDGQIFLQSDLFFSGVRPAIDAG
HHHHCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEECCCHHCCCCHHHCCC
TSVSRVGGSAQIKAMSKVSGTLRLDLASYRELEAFAQFGSDLDKATQAKLNRGARTVEVL
CCHHHCCCCHHEEEHHHCCCEEEEEHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHH
KQGLHKPLRVEKQVIILYALTRGFLDDIPVVDITRFEEEFHAWLDSNATDLLEEIRTTKK
HHHCCCCCCHHHHEEEEEHHHHHHHCCCCCEEHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LADDDKFAAAINGFKKVFVASE
HCCCHHHHHHHHHHHHEEEECC
>Mature Secondary Structure 
SIRAEEISALIKQQIENYQSEIEVSDVGTVIQVGDGIARAHGLDNVMAGELVEFSNGVM
CCCHHHHHHHHHHHHHHHHHHEEHHHCCCEEEECCCHHHHCCCCHHHHHHHHHHCCCHH
GLAQNLEENNVGIIILGPYTEIREGDEVRRTGRIMQVPVGKELIGRVVNPLGQPVDGLGP
HHHHCCCCCCEEEEEECCCHHHHCCHHHHHCCCEEECCCCHHHHHHHHHHCCCCCCCCCC
INTTNTRPIESPAPGVMDRKSVHEPLQTGIKAIDALVPIGRGQRELIIGDRQTGKTAVAL
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHH
DTIINQKDEDMICIYVAIGQKESTVRNVVETLRKHGALEYTIVVTASASQPAPLLYLAPY
HHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCEEEECCC
AGVTMGEEFMYNGKHVLVVYDDLSKQAAAYRELSLLLRRPPGREAYPGDVFYLHSRLLER
CCCCCCHHHEECCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
AAKLSDAKGGGSLTALPFIETQAGDVSAYIPTNVISITDGQIFLQSDLFFSGVRPAIDAG
HHHHCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEECCCHHCCCCHHHCCC
TSVSRVGGSAQIKAMSKVSGTLRLDLASYRELEAFAQFGSDLDKATQAKLNRGARTVEVL
CCHHHCCCCHHEEEHHHCCCEEEEEHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHH
KQGLHKPLRVEKQVIILYALTRGFLDDIPVVDITRFEEEFHAWLDSNATDLLEEIRTTKK
HHHCCCCCCHHHHEEEEEHHHHHHHCCCCCEEHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LADDDKFAAAINGFKKVFVASE
HCCCHHHHHHHHHHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12721630