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The map label for this gene is ywlE [H]

Identifier: 52140243

GI number: 52140243

Start: 5118337

End: 5118777

Strand: Reverse

Name: ywlE [H]

Synonym: BCZK5018

Alternate gene names: 52140243

Gene position: 5118777-5118337 (Counterclockwise)

Preceding gene: 52140240

Following gene: 52140245

Centisome position: 96.56

GC content: 39.68

Gene sequence:

>441_bases
ATGAAACGAGTATTATTTGTTTGCACTGGAAATACATGCCGTAGCCCGATGGCCGAGGCGTTACTTCGTCATCATGGGGA
AGGTAAGTTTGAAGTGCAATCTGCTGGTGTTTTTGCCTATCCTGGAAGTGATGCATCGGTACATGCAAAGGAAGCTTTAG
CTGAAAAGGGAATTGCAATCGATCATACCGCACAGCAGATAAACGAAACTTTGATTGATTGGGCAGATATTATAGTAACA
ATGACGGAAAACCATAGACAAATTGTACTTGGGCATTATCCGAGTGTTGAAAAGAAAGTAGATACGTTATATGGAGTAAC
TGAGGGGATAAGTAAGGATATTTCAGACCCATTTGGCGGATCGCTTTCTATTTATAAAGAAACGTTAGAAGAGATGGAAA
AACTTGTACAAACTTTACTGAAAAAGCATTCAGAAGGTTGA

Upstream 100 bases:

>100_bases
TATAAGAGAAATGCGCCTTTCGTATATTCACATTTCTTTTGTTCTATTGTAATGTACGCTATGATAAAAGGTAGGAAATA
GAGAAAAGGGGTGGGTTTAG

Downstream 100 bases:

>100_bases
TGTTTCGTGTATAATACGATATTGGAGATCACTTCGTTCCATCGTAGGAGCGAGTGAGAAATGAAGATAATGGATTGAAA
CTTTGGAGGGGTAAAAATGA

Product: protein tyrosine phosphatase

Products: NA

Alternate protein names: LMPTP [H]

Number of amino acids: Translated: 146; Mature: 146

Protein sequence:

>146_residues
MKRVLFVCTGNTCRSPMAEALLRHHGEGKFEVQSAGVFAYPGSDASVHAKEALAEKGIAIDHTAQQINETLIDWADIIVT
MTENHRQIVLGHYPSVEKKVDTLYGVTEGISKDISDPFGGSLSIYKETLEEMEKLVQTLLKKHSEG

Sequences:

>Translated_146_residues
MKRVLFVCTGNTCRSPMAEALLRHHGEGKFEVQSAGVFAYPGSDASVHAKEALAEKGIAIDHTAQQINETLIDWADIIVT
MTENHRQIVLGHYPSVEKKVDTLYGVTEGISKDISDPFGGSLSIYKETLEEMEKLVQTLLKKHSEG
>Mature_146_residues
MKRVLFVCTGNTCRSPMAEALLRHHGEGKFEVQSAGVFAYPGSDASVHAKEALAEKGIAIDHTAQQINETLIDWADIIVT
MTENHRQIVLGHYPSVEKKVDTLYGVTEGISKDISDPFGGSLSIYKETLEEMEKLVQTLLKKHSEG

Specific function: Dephosphorylates the phosphotyrosine-containing proteins. Involved in ethanol stress resistance [H]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase family [H]

Homologues:

Organism=Escherichia coli, GI1788375, Length=133, Percent_Identity=34.5864661654135, Blast_Score=65, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000106
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 16084; Mature: 16084

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRVLFVCTGNTCRSPMAEALLRHHGEGKFEVQSAGVFAYPGSDASVHAKEALAEKGIAI
CCEEEEEECCCCCCCHHHHHHHHHCCCCCEEEECCCEEEECCCCCCHHHHHHHHHCCCCC
DHTAQQINETLIDWADIIVTMTENHRQIVLGHYPSVEKKVDTLYGVTEGISKDISDPFGG
CHHHHHHHHHHHHHHHHHEEECCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCC
SLSIYKETLEEMEKLVQTLLKKHSEG
CHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKRVLFVCTGNTCRSPMAEALLRHHGEGKFEVQSAGVFAYPGSDASVHAKEALAEKGIAI
CCEEEEEECCCCCCCHHHHHHHHHCCCCCEEEECCCEEEECCCCCCHHHHHHHHHCCCCC
DHTAQQINETLIDWADIIVTMTENHRQIVLGHYPSVEKKVDTLYGVTEGISKDISDPFGG
CHHHHHHHHHHHHHHHHHEEECCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCC
SLSIYKETLEEMEKLVQTLLKKHSEG
CHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7798145; 9384377 [H]