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The map label for this gene is glpX [H]

Identifier: 52140228

GI number: 52140228

Start: 5131000

End: 5131965

Strand: Reverse

Name: glpX [H]

Synonym: BCZK5033

Alternate gene names: 52140228

Gene position: 5131965-5131000 (Counterclockwise)

Preceding gene: 52140226

Following gene: 52140230

Centisome position: 96.81

GC content: 43.27

Gene sequence:

>966_bases
GTGGAAAGAAGTTTATCTATGGAGTTAGTACGTGTAACAGAGGCTGCAGCTTTATCATCAGCGCGTTGGATGGGACGCGG
GAAAAAGGATGAGGCAGACGGTGCAGCAACATCAGCTATGCGTGATGTATTTGATACAATTCCGATGAAAGGTACAGTTG
TAATTGGTGAAGGTGAAATGGATGAAGCACCAATGCTATATATCGGAGAAAAATTAGGTACAGGATATGGTCCGCGTGTA
GACGTTGCAGTTGATCCTTTAGAAGGGACAAACATTGTAGCAGCTGGTGGATGGAATGCTCTTGCTGTTATTGCAATTGC
AGATCACGGTAATTTGTTACATGCTCCTGACATGTACATGGATAAAATCGCGGTTGGCCCAGAAGCGGTTGGGGCGGTCG
ATATTGATGCGCCTATTATTGATAACTTACGTGCAGTTGCGAAAGCGAAAAACAAAGATATTGAAGATGTTGTAGCGACA
GTTTTAAACCGTCCACGTCATCAAGCGATTATTGAAGAAATTCGTAAAGCTGGTGCTCGTATTAAATTGATTAATGATGG
AGACGTAGCAGGTGCAATTAATACTGCATTTGATCGTACAGGTGTAGATATTTTATTCGGATCTGGTGGTGCGCCTGAGG
GTGTATTAGCAGCAGTTGCATTAAAGTGTTTAGGTGGAGAGATTCACGGGAAATTATTACCACAAAACGAAGCTGAATTG
GCGCGTTGCAAAAAGATGGGCATAGAAGACATCAACCGCATCCTTCGCATGGAAGACTTAGTAAAAGGTGACGATGCAAT
CTTCGCAGCAACAGGCGTAACAGACGGAGAACTACTACGCGGCGTTCAATTTAAAGGTAGCGTAGGAACAACACAATCTC
TTGTTATGCGTGCAAAATCAGGCACAGTACGCTTCGTAGACGGACGTCACAGCTTGAATAAAAAACCGAACTTGGTTATT
AAATAA

Upstream 100 bases:

>100_bases
GGGAAGCGAAGCATCACTACTTGCGGAAGTACACTTTATAGAAAAAACACGGTTCACAAAATACGGCAGAAATATAAAGA
CTTAAAGGAGAGGGATTATC

Downstream 100 bases:

>100_bases
AAAGTGTAAGCGGCTCGTTCAGAATGGTAGGAAGAAGTGAAGCCACCAATCATTCTAGCTGCTGAAGCTGGATTAAATAA
AAAGCGAAGACAAATTTTCT

Product: fructose 1,6-bisphosphatase II

Products: NA

Alternate protein names: FBPase class 2; D-fructose-1,6-bisphosphate 1-phosphohydrolase class 2 [H]

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MERSLSMELVRVTEAAALSSARWMGRGKKDEADGAATSAMRDVFDTIPMKGTVVIGEGEMDEAPMLYIGEKLGTGYGPRV
DVAVDPLEGTNIVAAGGWNALAVIAIADHGNLLHAPDMYMDKIAVGPEAVGAVDIDAPIIDNLRAVAKAKNKDIEDVVAT
VLNRPRHQAIIEEIRKAGARIKLINDGDVAGAINTAFDRTGVDILFGSGGAPEGVLAAVALKCLGGEIHGKLLPQNEAEL
ARCKKMGIEDINRILRMEDLVKGDDAIFAATGVTDGELLRGVQFKGSVGTTQSLVMRAKSGTVRFVDGRHSLNKKPNLVI
K

Sequences:

>Translated_321_residues
MERSLSMELVRVTEAAALSSARWMGRGKKDEADGAATSAMRDVFDTIPMKGTVVIGEGEMDEAPMLYIGEKLGTGYGPRV
DVAVDPLEGTNIVAAGGWNALAVIAIADHGNLLHAPDMYMDKIAVGPEAVGAVDIDAPIIDNLRAVAKAKNKDIEDVVAT
VLNRPRHQAIIEEIRKAGARIKLINDGDVAGAINTAFDRTGVDILFGSGGAPEGVLAAVALKCLGGEIHGKLLPQNEAEL
ARCKKMGIEDINRILRMEDLVKGDDAIFAATGVTDGELLRGVQFKGSVGTTQSLVMRAKSGTVRFVDGRHSLNKKPNLVI
K
>Mature_321_residues
MERSLSMELVRVTEAAALSSARWMGRGKKDEADGAATSAMRDVFDTIPMKGTVVIGEGEMDEAPMLYIGEKLGTGYGPRV
DVAVDPLEGTNIVAAGGWNALAVIAIADHGNLLHAPDMYMDKIAVGPEAVGAVDIDAPIIDNLRAVAKAKNKDIEDVVAT
VLNRPRHQAIIEEIRKAGARIKLINDGDVAGAINTAFDRTGVDILFGSGGAPEGVLAAVALKCLGGEIHGKLLPQNEAEL
ARCKKMGIEDINRILRMEDLVKGDDAIFAATGVTDGELLRGVQFKGSVGTTQSLVMRAKSGTVRFVDGRHSLNKKPNLVI
K

Specific function: Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate. Can functionally substitute for the FBPase class 3 (Fbp) of B.subtilis [H]

COG id: COG1494

COG function: function code G; Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FBPase class 2 family [H]

Homologues:

Organism=Escherichia coli, GI1790360, Length=328, Percent_Identity=49.390243902439, Blast_Score=324, Evalue=4e-90,
Organism=Escherichia coli, GI1789298, Length=320, Percent_Identity=45, Blast_Score=268, Evalue=3e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004464 [H]

Pfam domain/function: PF03320 FBPase_glpX [H]

EC number: =3.1.3.11 [H]

Molecular weight: Translated: 33958; Mature: 33958

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERSLSMELVRVTEAAALSSARWMGRGKKDEADGAATSAMRDVFDTIPMKGTVVIGEGEM
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCC
DEAPMLYIGEKLGTGYGPRVDVAVDPLEGTNIVAAGGWNALAVIAIADHGNLLHAPDMYM
CCCCEEEEEHHHCCCCCCEEEEEECCCCCCEEEEECCCCEEEEEEEECCCCEEECCCHHH
DKIAVGPEAVGAVDIDAPIIDNLRAVAKAKNKDIEDVVATVLNRPRHQAIIEEIRKAGAR
HHHCCCCCCCCEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHCCCE
IKLINDGDVAGAINTAFDRTGVDILFGSGGAPEGVLAAVALKCLGGEIHGKLLPQNEAEL
EEEEECCCCCCHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHH
ARCKKMGIEDINRILRMEDLVKGDDAIFAATGVTDGELLRGVQFKGSVGTTQSLVMRAKS
HHHHHCCHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHCCEEECCCCCCHHHHHEEECC
GTVRFVDGRHSLNKKPNLVIK
CCEEEECCCCCCCCCCCEEEC
>Mature Secondary Structure
MERSLSMELVRVTEAAALSSARWMGRGKKDEADGAATSAMRDVFDTIPMKGTVVIGEGEM
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCC
DEAPMLYIGEKLGTGYGPRVDVAVDPLEGTNIVAAGGWNALAVIAIADHGNLLHAPDMYM
CCCCEEEEEHHHCCCCCCEEEEEECCCCCCEEEEECCCCEEEEEEEECCCCEEECCCHHH
DKIAVGPEAVGAVDIDAPIIDNLRAVAKAKNKDIEDVVATVLNRPRHQAIIEEIRKAGAR
HHHCCCCCCCCEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHCCCE
IKLINDGDVAGAINTAFDRTGVDILFGSGGAPEGVLAAVALKCLGGEIHGKLLPQNEAEL
EEEEECCCCCCHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHH
ARCKKMGIEDINRILRMEDLVKGDDAIFAATGVTDGELLRGVQFKGSVGTTQSLVMRAKS
HHHHHCCHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHCCEEECCCCCCHHHHHEEECC
GTVRFVDGRHSLNKKPNLVIK
CCEEEECCCCCCCCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8423140; 9353933; 9384377 [H]