Click here to switch to the map view.

The map label for this gene is sigW [H]

Identifier: 52140200

GI number: 52140200

Start: 5171651

End: 5172184

Strand: Reverse

Name: sigW [H]

Synonym: BCZK5060

Alternate gene names: 52140200

Gene position: 5172184-5171651 (Counterclockwise)

Preceding gene: 52140201

Following gene: 52140202

Centisome position: 97.57

GC content: 32.4

Gene sequence:

>534_bases
ATGGAAGAAAAGGTAGAAGAATTAATTGATATATATAAGCAGCAAATATATTCCTTATGCTATAAGTTAGCGAAGACGAA
AGAAGACGCGGAAGATATTTTTCAAGAGACGTGGATAAAAGTTTTTTCATCGCGGCACCAACTTTCTTACGTGGAGAATT
ATAAAAAGTGGATTACTACAATTTGTGTTCGTACGTTTTATGATTTTTATCGCAAAAAGAAAAGGTGGAAAGATCGTGTA
TTGGATTTATTTCATAAAGAAGATGGTGGAGAAATAGAGTTTGCAGATGATGTGAATATATCCGAAGAATTCATTCAAAA
AGTCGAAGCAGAAATGATACGAGAAGTTATACAGTTATTAAACGAAAAATATAAAACAGTGCTCGTACTCTACTATTATG
AACAATATTCTTACAAAGAAATGAGTGAAATATTAAATATACCAATTGGTACGGTGAAATACCGTCTTAATTATGCGAAG
AAGCGAATGCGAGAACATTTGGAGGGGTTCGTTTATGAAGGAAGACAAATTTGA

Upstream 100 bases:

>100_bases
TGTTGTGATTGCCTTTTTGTATGGAGATAATAAAAAAATAAGATTTTATCAAACAAAAGGAGAATTTGCGTCGTCTTATA
TAAATGACAGGAGGTTTCAG

Downstream 100 bases:

>100_bases
TCAAAAGATAAAAAGTAGTTTAGCGGAAGAGATGATTCCTAGCGAAGAGCTAATAAATAATACGAAGCAGGGCATGCGAA
ATGCTCGGAAATTAGAGAAG

Product: RNA polymerase sigma factor

Products: NA

Alternate protein names: Sigma-W factor [H]

Number of amino acids: Translated: 177; Mature: 177

Protein sequence:

>177_residues
MEEKVEELIDIYKQQIYSLCYKLAKTKEDAEDIFQETWIKVFSSRHQLSYVENYKKWITTICVRTFYDFYRKKKRWKDRV
LDLFHKEDGGEIEFADDVNISEEFIQKVEAEMIREVIQLLNEKYKTVLVLYYYEQYSYKEMSEILNIPIGTVKYRLNYAK
KRMREHLEGFVYEGRQI

Sequences:

>Translated_177_residues
MEEKVEELIDIYKQQIYSLCYKLAKTKEDAEDIFQETWIKVFSSRHQLSYVENYKKWITTICVRTFYDFYRKKKRWKDRV
LDLFHKEDGGEIEFADDVNISEEFIQKVEAEMIREVIQLLNEKYKTVLVLYYYEQYSYKEMSEILNIPIGTVKYRLNYAK
KRMREHLEGFVYEGRQI
>Mature_177_residues
MEEKVEELIDIYKQQIYSLCYKLAKTKEDAEDIFQETWIKVFSSRHQLSYVENYKKWITTICVRTFYDFYRKKKRWKDRV
LDLFHKEDGGEIEFADDVNISEEFIQKVEAEMIREVIQLLNEKYKTVLVLYYYEQYSYKEMSEILNIPIGTVKYRLNYAK
KRMREHLEGFVYEGRQI

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Sigma-W controls genes involved in transport processes and detoxification [H]

COG id: COG1595

COG function: function code K; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR014294
- InterPro:   IPR000838
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR013325
- InterPro:   IPR013324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 21760; Mature: 21760

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEEKVEELIDIYKQQIYSLCYKLAKTKEDAEDIFQETWIKVFSSRHQLSYVENYKKWITT
CCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ICVRTFYDFYRKKKRWKDRVLDLFHKEDGGEIEFADDVNISEEFIQKVEAEMIREVIQLL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHH
NEKYKTVLVLYYYEQYSYKEMSEILNIPIGTVKYRLNYAKKRMREHLEGFVYEGRQI
HHHHHHHHHHHHHHHHCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MEEKVEELIDIYKQQIYSLCYKLAKTKEDAEDIFQETWIKVFSSRHQLSYVENYKKWITT
CCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ICVRTFYDFYRKKKRWKDRVLDLFHKEDGGEIEFADDVNISEEFIQKVEAEMIREVIQLL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHH
NEKYKTVLVLYYYEQYSYKEMSEILNIPIGTVKYRLNYAKKRMREHLEGFVYEGRQI
HHHHHHHHHHHHHHHHCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274029; 9384377; 12207695 [H]