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The map label for this gene is fhuG [H]

Identifier: 52140184

GI number: 52140184

Start: 5189752

End: 5190768

Strand: Reverse

Name: fhuG [H]

Synonym: BCZK5079

Alternate gene names: 52140184

Gene position: 5190768-5189752 (Counterclockwise)

Preceding gene: 52140182

Following gene: 52140183

Centisome position: 97.92

GC content: 38.64

Gene sequence:

>1017_bases
GTGAGGACAAGTGTCTTAACAAAAAAGAACGTTTCTGTTTTAACAATTTTAGTAGGATTAATCGTTACTGTATTTTTAGT
GAGTTTAAATACAGGGACATTTAAAATCCCGCCAATGGATGTATTAAAGTCATTGGTTGGACTTGGGGCTGAAGATCAGT
CTGTTATTTTATTTGAATTTCGTATGCCACGTATGGTCATTGCTATATTAGTTGGATCGGCTTTAGCTATGTCAGGTGCG
ATTTTGCAAGGGTTATCACGAAATCCACTTGCTGATCCAGGTATTATCGGTATTAACGCTGGAGCAGGATTAACAGTTGT
TATATTTGTCTACTTTTTCTTCGGGAAAATTGGGACTGGTACATTTTTATCTGTATTTATCCTTCCGTTTTTCGCGTTAG
TTGGAGCGATATTAGCTGCGGTTATTATTTATTTACTAGCATGGAAAGACGGCGTTTCATCTACTCGATTGATACTTGTG
GGTATCGCTGTTGCAGCTGGGTTTGGTGCTGTTAGTTTAATTTTTTCTATGAAGATGACATCTAACGATTTCCGCTTTGC
TACGATTTGGTTAGCAGGAAGTCTTTGGGGCACAGATTGGAAGTTCGTGCTAAGTGTCCTTCCATGGATGGTTATTTTCT
TGCCACTAGCTATTAGTAAAGCACACATACTAAATGTAATGAACCTAGGCGACTCTACAGCAGTTGGTCTTGGTGTAAAC
GTAGAAAAGGAAAGACGTAAATTATTATTTATTGCAGTTTGTTTAGCAGGTGCATCTGTCGCTGTTGCCGGAGGAATTGG
TTTTATCGGTTTAATGGCTCCACATTTAGCGAGGCGCCTTGTTGGTGGGAAACATCAAATTATGCTGCCTACAGCTGCAC
TAATAGGAACGTTTTTACTTTTATTCGCAGACGTAATTTCAAGAAGTGTGTTACCAACTTCAGAAATACCGGTCGGTCTT
GTTATTTCTGTAATTGGTGCACCGTATTTTATATACTTACTTATGAGGACAAAGTAA

Upstream 100 bases:

>100_bases
TTATTAACCCGCCGTTTGAAACGCCAATTGGAGCAATTACAGCGCTAATTGGAGTTCCATTCTTCCTCTACTTAGCACGT
AACGAAGGGAGAGGGAAAAT

Downstream 100 bases:

>100_bases
AGGGAGGCTTTTTGTATGGCAACTTTAGCAGTTGATGCGGTATCTGTTGGCTATAATGAAGGGTTAATTATTGATGGATT
AACAGTTGAAATTCCGGAAG

Product: iron compound ABC transporter, permease

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: Ferric hydroxamate uptake protein G; Ferrichrome transport system permease protein fhuG; Iron(III)-hydroxamate import system permease protein fhuG [H]

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MRTSVLTKKNVSVLTILVGLIVTVFLVSLNTGTFKIPPMDVLKSLVGLGAEDQSVILFEFRMPRMVIAILVGSALAMSGA
ILQGLSRNPLADPGIIGINAGAGLTVVIFVYFFFGKIGTGTFLSVFILPFFALVGAILAAVIIYLLAWKDGVSSTRLILV
GIAVAAGFGAVSLIFSMKMTSNDFRFATIWLAGSLWGTDWKFVLSVLPWMVIFLPLAISKAHILNVMNLGDSTAVGLGVN
VEKERRKLLFIAVCLAGASVAVAGGIGFIGLMAPHLARRLVGGKHQIMLPTAALIGTFLLLFADVISRSVLPTSEIPVGL
VISVIGAPYFIYLLMRTK

Sequences:

>Translated_338_residues
MRTSVLTKKNVSVLTILVGLIVTVFLVSLNTGTFKIPPMDVLKSLVGLGAEDQSVILFEFRMPRMVIAILVGSALAMSGA
ILQGLSRNPLADPGIIGINAGAGLTVVIFVYFFFGKIGTGTFLSVFILPFFALVGAILAAVIIYLLAWKDGVSSTRLILV
GIAVAAGFGAVSLIFSMKMTSNDFRFATIWLAGSLWGTDWKFVLSVLPWMVIFLPLAISKAHILNVMNLGDSTAVGLGVN
VEKERRKLLFIAVCLAGASVAVAGGIGFIGLMAPHLARRLVGGKHQIMLPTAALIGTFLLLFADVISRSVLPTSEIPVGL
VISVIGAPYFIYLLMRTK
>Mature_338_residues
MRTSVLTKKNVSVLTILVGLIVTVFLVSLNTGTFKIPPMDVLKSLVGLGAEDQSVILFEFRMPRMVIAILVGSALAMSGA
ILQGLSRNPLADPGIIGINAGAGLTVVIFVYFFFGKIGTGTFLSVFILPFFALVGAILAAVIIYLLAWKDGVSSTRLILV
GIAVAAGFGAVSLIFSMKMTSNDFRFATIWLAGSLWGTDWKFVLSVLPWMVIFLPLAISKAHILNVMNLGDSTAVGLGVN
VEKERRKLLFIAVCLAGASVAVAGGIGFIGLMAPHLARRLVGGKHQIMLPTAALIGTFLLLFADVISRSVLPTSEIPVGL
VISVIGAPYFIYLLMRTK

Specific function: Part of the ABC transporter complex fhuBGCD involved in iron(3+)-hydroxamate import. Responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790740, Length=313, Percent_Identity=37.3801916932907, Blast_Score=200, Evalue=1e-52,
Organism=Escherichia coli, GI1786804, Length=323, Percent_Identity=33.4365325077399, Blast_Score=144, Evalue=7e-36,
Organism=Escherichia coli, GI1788004, Length=290, Percent_Identity=34.1379310344828, Blast_Score=132, Evalue=4e-32,
Organism=Escherichia coli, GI1790741, Length=283, Percent_Identity=34.2756183745583, Blast_Score=131, Evalue=6e-32,
Organism=Escherichia coli, GI1786805, Length=313, Percent_Identity=35.1437699680511, Blast_Score=127, Evalue=7e-31,
Organism=Escherichia coli, GI1786347, Length=288, Percent_Identity=34.7222222222222, Blast_Score=123, Evalue=1e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 35897; Mature: 35897

Theoretical pI: Translated: 10.79; Mature: 10.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTSVLTKKNVSVLTILVGLIVTVFLVSLNTGTFKIPPMDVLKSLVGLGAEDQSVILFEF
CCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHCCCCCCCEEEEEEE
RMPRMVIAILVGSALAMSGAILQGLSRNPLADPGIIGINAGAGLTVVIFVYFFFGKIGTG
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCH
TFLSVFILPFFALVGAILAAVIIYLLAWKDGVSSTRLILVGIAVAAGFGAVSLIFSMKMT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
SNDFRFATIWLAGSLWGTDWKFVLSVLPWMVIFLPLAISKAHILNVMNLGDSTAVGLGVN
CCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCC
VEKERRKLLFIAVCLAGASVAVAGGIGFIGLMAPHLARRLVGGKHQIMLPTAALIGTFLL
CHHHHHHHHHHHHHHHCCHHEECCCHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHH
LFADVISRSVLPTSEIPVGLVISVIGAPYFIYLLMRTK
HHHHHHHHCCCCCCCCCHHHHHHHHCCHHHHHEEEECC
>Mature Secondary Structure
MRTSVLTKKNVSVLTILVGLIVTVFLVSLNTGTFKIPPMDVLKSLVGLGAEDQSVILFEF
CCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHCCCCCCCEEEEEEE
RMPRMVIAILVGSALAMSGAILQGLSRNPLADPGIIGINAGAGLTVVIFVYFFFGKIGTG
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCH
TFLSVFILPFFALVGAILAAVIIYLLAWKDGVSSTRLILVGIAVAAGFGAVSLIFSMKMT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
SNDFRFATIWLAGSLWGTDWKFVLSVLPWMVIFLPLAISKAHILNVMNLGDSTAVGLGVN
CCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCC
VEKERRKLLFIAVCLAGASVAVAGGIGFIGLMAPHLARRLVGGKHQIMLPTAALIGTFLL
CHHHHHHHHHHHHHHHCCHHEECCCHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHH
LFADVISRSVLPTSEIPVGLVISVIGAPYFIYLLMRTK
HHHHHHHHCCCCCCCCCHHHHHHHHCCHHHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9639930; 9384377 [H]