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The map label for this gene is metS2 [H]

Identifier: 51893951

GI number: 51893951

Start: 3026961

End: 3027422

Strand: Reverse

Name: metS2 [H]

Synonym: STH2813

Alternate gene names: 51893951

Gene position: 3027422-3026961 (Counterclockwise)

Preceding gene: 51893952

Following gene: 51893950

Centisome position: 84.89

GC content: 72.94

Gene sequence:

>462_bases
GTGCCGGCCGGCGGCGAGCCCGGGGAGCGGGAGCAGGCGCTGGCCCGGGAGTGCGCCGCGGCCGTCGGGGAGTACCGGTC
GCACCTGCGGAGCGTGGAGTTCCGCAAGGCCGTGCAGGCGATGCGTCGGCTCTGCACCCTGGGCAACCGCTACCTAGAGG
ACCGGGCCCCCTGGAACCTGGTGAAGGAGGACCGGGAGGCGGGGGCCATGGTCCTGCGCACCGCGCTGAACCTGGTCCGC
ATCTTCGCGCTTGCGGCGGAGCCGATCCTCCCCTTCACCGCCCAGAGGGTGTTCGACGCCCTGCAGTTGACGCCGGATGA
ACGGAAGGTCCCCCTGCAGCGGTGCGTCGACCTGTCTGCGCTGGCTCCGGGCAGGCAGTTCCAGCTCATCCCGCCGCTGT
TCCGCCGCCTGGAGGCCGCCGAAGTGGAGCGGCTGAAGGCGCGGTTCGGGGGGCGGGACTGA

Upstream 100 bases:

>100_bases
GGTTTGTCCAGGGGCGCACTGTGCTTCGATATTTGCCTTCGCAATTGCTGAACGCATACTCAGGGAGAGGACGCTTACCC
CACTTTGACTTGACAGCTAC

Downstream 100 bases:

>100_bases
GGCAGGGAATTCCGGACGCAGGCTGGAAATGTCTGTGGCAAGACGACCCTGGGTCGGGAAGGGTGGGAGTTGGTTGCATG
GTTCACATTTCTGCCCGCGT

Product: methionyl-tRNA synthetase

Products: NA

Alternate protein names: Methionine--tRNA ligase 1; MetRS 1 [H]

Number of amino acids: Translated: 153; Mature: 152

Protein sequence:

>153_residues
MPAGGEPGEREQALARECAAAVGEYRSHLRSVEFRKAVQAMRRLCTLGNRYLEDRAPWNLVKEDREAGAMVLRTALNLVR
IFALAAEPILPFTAQRVFDALQLTPDERKVPLQRCVDLSALAPGRQFQLIPPLFRRLEAAEVERLKARFGGRD

Sequences:

>Translated_153_residues
MPAGGEPGEREQALARECAAAVGEYRSHLRSVEFRKAVQAMRRLCTLGNRYLEDRAPWNLVKEDREAGAMVLRTALNLVR
IFALAAEPILPFTAQRVFDALQLTPDERKVPLQRCVDLSALAPGRQFQLIPPLFRRLEAAEVERLKARFGGRD
>Mature_152_residues
PAGGEPGEREQALARECAAAVGEYRSHLRSVEFRKAVQAMRRLCTLGNRYLEDRAPWNLVKEDREAGAMVLRTALNLVRI
FALAAEPILPFTAQRVFDALQLTPDERKVPLQRCVDLSALAPGRQFQLIPPLFRRLEAAEVERLKARFGGRD

Specific function: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation [H]

COG id: COG0143

COG function: function code J; Methionyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI14043022, Length=144, Percent_Identity=27.7777777777778, Blast_Score=67, Evalue=5e-12,

Paralogues:

None

Copy number: 871 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015413
- InterPro:   IPR014758
- InterPro:   IPR014729
- InterPro:   IPR009080
- InterPro:   IPR013155 [H]

Pfam domain/function: PF08264 Anticodon_1; PF09334 tRNA-synt_1g [H]

EC number: =6.1.1.10 [H]

Molecular weight: Translated: 17239; Mature: 17108

Theoretical pI: Translated: 9.86; Mature: 9.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAGGEPGEREQALARECAAAVGEYRSHLRSVEFRKAVQAMRRLCTLGNRYLEDRAPWNL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
VKEDREAGAMVLRTALNLVRIFALAAEPILPFTAQRVFDALQLTPDERKVPLQRCVDLSA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
LAPGRQFQLIPPLFRRLEAAEVERLKARFGGRD
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PAGGEPGEREQALARECAAAVGEYRSHLRSVEFRKAVQAMRRLCTLGNRYLEDRAPWNL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
VKEDREAGAMVLRTALNLVRIFALAAEPILPFTAQRVFDALQLTPDERKVPLQRCVDLSA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
LAPGRQFQLIPPLFRRLEAAEVERLKARFGGRD
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA