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The map label for this gene is yisV [H]

Identifier: 51893892

GI number: 51893892

Start: 2972950

End: 2974419

Strand: Reverse

Name: yisV [H]

Synonym: STH2754

Alternate gene names: 51893892

Gene position: 2974419-2972950 (Counterclockwise)

Preceding gene: 51893893

Following gene: 51893891

Centisome position: 83.41

GC content: 71.97

Gene sequence:

>1470_bases
GTGTTCAAGCTGGATCGCACCAGCGCGACGCCGCTGTACCGGCAGCTCTACGCACAGGCGAAGGAGCGCATCCTCTCGGG
CGCGCTGCCCCCCGGCACCCGGCTCCCGCCGGAACGGACCCTGGCCCGCAGGCTCGGGGTCAACCGGACCACCGTCGTCA
ACGCCTACCGGGAGCTGGCGGCGGAGGGGCTGGTGGAGGGGCGGGTCGGCCACGGCACGGTGGTGCTCGGGCCGCCTGAG
CCGCGGGGGGCCGACGCGGTCCGCCCGATGCCGTGGGCCGGCCCCACCGAGGCCGAAGAGCCGCTGGTCGCGGACATCAA
CGCCATCATCCGGCGGCCCGGCGCCATTTCCTTCGCCCACGGCGAGATGTCGCCCGAGCTGTACCCGGCCGAGGCCGTTG
CCCACCTCATGCAGCAGGTCCTGCAGGATCCGGCCGCCCTGGGTTACGGGCCCATCGCCGGCCTCATGCCGCTCCGACAG
GCGATTGCCGACGCCATGGGGGTCACGGCAGATCAGGTGCTCATCCTGGCCGGGTCGCAGATCGCCCTCTACCTGATCAG
CCGGGTCCTGCTGCAGCCCGGCGACACGGTGTTGGTCGAAATGCCGTCCTACATTAACACGTTGGGCATTTTCGATTCCG
CCGGCGTCCGGGTGGTTCCGGTGCCGGTCGACCAGCACGGCCTGGTGGTCGACGGGCTGGACGAGCTGATGCTCCGGTAT
CAGCCGAAGCTGCTGTTTACCCTTCCCACCTTCCACAACCCCCTCGGCGTGACGCTCACCCCCGAGCGCCGCCGGCGGCT
GATCCAGCTGGCCGCCCGCCACCAGGTGGGCATCGTGGAGGATGACCCTTACGGGCCGCTCCACTTCACCGGGCAGCCGG
TGCCCACCCTGAAGTCGCTGGATCCCGGCGGGTACGTCATCTACATCAGCAGCGCGAGCAAGGCGGTCAGCCCGGCCCTG
CGGCTGGCCTGGATCGTCGCCGCCCCGCCGGTAGTGGAGCGCATCGCCCGCGCCCGGGGCAGCCTGGACTTCCGGGCCGC
CCTGCTCAACCAGCGGGTAATGGAAGCGTTCCTCCGGGAGGGGCTGCTCGCCGAGCACCTGGGGCGGCTCAGGCCCGCTC
TGAAGGAGCGGCGGGACCTCATGCTGGAGGCGCTGCAGCGGTACATGCCCGACGGGGTCAGCTGGTACGTGCCGGAGGGT
GGCTACCACATCTGGTGCCGGCTGCCCCGGCCGCTCACGGCCCGGAGGCTGCTCACTGAGGCCGGCCGTGAGGGGGTGGC
CTTCGTGCCGGGGGATTTCTACGGCGCCGGCCAGATGGCCCGACGGGGCCTCCGGCTGAACTTCTCCTACCCTCGCCCCG
AGGAGATCGGGCCCGGCATCGCCCGGCTCGCCCGGGCGGTGGAGCGGCTGCTGCGGGAGGAGGCGGTCGACGGGGGCGAG
GAGGCGTCCATCAGCGGTCCGGTGGTCTGA

Upstream 100 bases:

>100_bases
GCAAGAGCGCCGATCCTGCCCGCCGCAGGGTCGGCGCCTCGCGTTTGGTGTGCTACAATCAGCAGTGCGGCAGACCGAGC
ATGGGAAGGGGGAAACGAGC

Downstream 100 bases:

>100_bases
ACGGGGAGGATACACGACGGCGGGCGGTAAGCCCGCCGTTTTCGCGTCGGGTCGTTCCGAGGGGCTCCGGGCCGGGATGA
GATATAGAGATGCTCTATCG

Product: class I aminotransferase protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 489; Mature: 489

Protein sequence:

>489_residues
MFKLDRTSATPLYRQLYAQAKERILSGALPPGTRLPPERTLARRLGVNRTTVVNAYRELAAEGLVEGRVGHGTVVLGPPE
PRGADAVRPMPWAGPTEAEEPLVADINAIIRRPGAISFAHGEMSPELYPAEAVAHLMQQVLQDPAALGYGPIAGLMPLRQ
AIADAMGVTADQVLILAGSQIALYLISRVLLQPGDTVLVEMPSYINTLGIFDSAGVRVVPVPVDQHGLVVDGLDELMLRY
QPKLLFTLPTFHNPLGVTLTPERRRRLIQLAARHQVGIVEDDPYGPLHFTGQPVPTLKSLDPGGYVIYISSASKAVSPAL
RLAWIVAAPPVVERIARARGSLDFRAALLNQRVMEAFLREGLLAEHLGRLRPALKERRDLMLEALQRYMPDGVSWYVPEG
GYHIWCRLPRPLTARRLLTEAGREGVAFVPGDFYGAGQMARRGLRLNFSYPRPEEIGPGIARLARAVERLLREEAVDGGE
EASISGPVV

Sequences:

>Translated_489_residues
MFKLDRTSATPLYRQLYAQAKERILSGALPPGTRLPPERTLARRLGVNRTTVVNAYRELAAEGLVEGRVGHGTVVLGPPE
PRGADAVRPMPWAGPTEAEEPLVADINAIIRRPGAISFAHGEMSPELYPAEAVAHLMQQVLQDPAALGYGPIAGLMPLRQ
AIADAMGVTADQVLILAGSQIALYLISRVLLQPGDTVLVEMPSYINTLGIFDSAGVRVVPVPVDQHGLVVDGLDELMLRY
QPKLLFTLPTFHNPLGVTLTPERRRRLIQLAARHQVGIVEDDPYGPLHFTGQPVPTLKSLDPGGYVIYISSASKAVSPAL
RLAWIVAAPPVVERIARARGSLDFRAALLNQRVMEAFLREGLLAEHLGRLRPALKERRDLMLEALQRYMPDGVSWYVPEG
GYHIWCRLPRPLTARRLLTEAGREGVAFVPGDFYGAGQMARRGLRLNFSYPRPEEIGPGIARLARAVERLLREEAVDGGE
EASISGPVV
>Mature_489_residues
MFKLDRTSATPLYRQLYAQAKERILSGALPPGTRLPPERTLARRLGVNRTTVVNAYRELAAEGLVEGRVGHGTVVLGPPE
PRGADAVRPMPWAGPTEAEEPLVADINAIIRRPGAISFAHGEMSPELYPAEAVAHLMQQVLQDPAALGYGPIAGLMPLRQ
AIADAMGVTADQVLILAGSQIALYLISRVLLQPGDTVLVEMPSYINTLGIFDSAGVRVVPVPVDQHGLVVDGLDELMLRY
QPKLLFTLPTFHNPLGVTLTPERRRRLIQLAARHQVGIVEDDPYGPLHFTGQPVPTLKSLDPGGYVIYISSASKAVSPAL
RLAWIVAAPPVVERIARARGSLDFRAALLNQRVMEAFLREGLLAEHLGRLRPALKERRDLMLEALQRYMPDGVSWYVPEG
GYHIWCRLPRPLTARRLLTEAGREGVAFVPGDFYGAGQMARRGLRLNFSYPRPEEIGPGIARLARAVERLLREEAVDGGE
EASISGPVV

Specific function: Unknown

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=352, Percent_Identity=28.9772727272727, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI33469970, Length=352, Percent_Identity=28.9772727272727, Blast_Score=157, Evalue=2e-38,
Organism=Escherichia coli, GI1787710, Length=477, Percent_Identity=29.559748427673, Blast_Score=181, Evalue=7e-47,
Organism=Escherichia coli, GI1790797, Length=472, Percent_Identity=29.0254237288136, Blast_Score=164, Evalue=1e-41,
Organism=Escherichia coli, GI1788722, Length=359, Percent_Identity=25.9052924791086, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI48994949, Length=404, Percent_Identity=24.7524752475248, Blast_Score=65, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6321236, Length=285, Percent_Identity=29.4736842105263, Blast_Score=105, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6321000, Length=426, Percent_Identity=24.1784037558685, Blast_Score=87, Evalue=7e-18,
Organism=Saccharomyces cerevisiae, GI6321929, Length=269, Percent_Identity=24.907063197026, Blast_Score=83, Evalue=1e-16,
Organism=Drosophila melanogaster, GI21356535, Length=371, Percent_Identity=26.1455525606469, Blast_Score=122, Evalue=4e-28,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 53388; Mature: 53388

Theoretical pI: Translated: 9.07; Mature: 9.07

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKLDRTSATPLYRQLYAQAKERILSGALPPGTRLPPERTLARRLGVNRTTVVNAYRELA
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHH
AEGLVEGRVGHGTVVLGPPEPRGADAVRPMPWAGPTEAEEPLVADINAIIRRPGAISFAH
HHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEC
GEMSPELYPAEAVAHLMQQVLQDPAALGYGPIAGLMPLRQAIADAMGVTADQVLILAGSQ
CCCCCCCCCHHHHHHHHHHHHHCHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCH
IALYLISRVLLQPGDTVLVEMPSYINTLGIFDSAGVRVVPVPVDQHGLVVDGLDELMLRY
HHHHHHHHHHHCCCCEEEEECCHHHHHHHCCCCCCCEEEEECCCCCCCEECCHHHHHHHC
QPKLLFTLPTFHNPLGVTLTPERRRRLIQLAARHQVGIVEDDPYGPLHFTGQPVPTLKSL
CCCEEEECCCCCCCCCEEECHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCHHCC
DPGGYVIYISSASKAVSPALRLAWIVAAPPVVERIARARGSLDFRAALLNQRVMEAFLRE
CCCCEEEEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHC
GLLAEHLGRLRPALKERRDLMLEALQRYMPDGVSWYVPEGGYHIWCRLPRPLTARRLLTE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEEEEECCCCHHHHHHHHH
AGREGVAFVPGDFYGAGQMARRGLRLNFSYPRPEEIGPGIARLARAVERLLREEAVDGGE
CCCCCEEECCCCCCCCHHHHHCCEEEECCCCCCHHCCCHHHHHHHHHHHHHHHHHCCCCC
EASISGPVV
CCCCCCCCC
>Mature Secondary Structure
MFKLDRTSATPLYRQLYAQAKERILSGALPPGTRLPPERTLARRLGVNRTTVVNAYRELA
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHH
AEGLVEGRVGHGTVVLGPPEPRGADAVRPMPWAGPTEAEEPLVADINAIIRRPGAISFAH
HHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEC
GEMSPELYPAEAVAHLMQQVLQDPAALGYGPIAGLMPLRQAIADAMGVTADQVLILAGSQ
CCCCCCCCCHHHHHHHHHHHHHCHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCH
IALYLISRVLLQPGDTVLVEMPSYINTLGIFDSAGVRVVPVPVDQHGLVVDGLDELMLRY
HHHHHHHHHHHCCCCEEEEECCHHHHHHHCCCCCCCEEEEECCCCCCCEECCHHHHHHHC
QPKLLFTLPTFHNPLGVTLTPERRRRLIQLAARHQVGIVEDDPYGPLHFTGQPVPTLKSL
CCCEEEECCCCCCCCCEEECHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCHHCC
DPGGYVIYISSASKAVSPALRLAWIVAAPPVVERIARARGSLDFRAALLNQRVMEAFLRE
CCCCEEEEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHC
GLLAEHLGRLRPALKERRDLMLEALQRYMPDGVSWYVPEGGYHIWCRLPRPLTARRLLTE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEEEEECCCCHHHHHHHHH
AGREGVAFVPGDFYGAGQMARRGLRLNFSYPRPEEIGPGIARLARAVERLLREEAVDGGE
CCCCCEEECCCCCCCCHHHHHCCEEEECCCCCCHHCCCHHHHHHHHHHHHHHHHHCCCCC
EASISGPVV
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]