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The map label for this gene is galE [H]

Identifier: 51893849

GI number: 51893849

Start: 2908161

End: 2909147

Strand: Reverse

Name: galE [H]

Synonym: STH2711

Alternate gene names: 51893849

Gene position: 2909147-2908161 (Counterclockwise)

Preceding gene: 51893850

Following gene: 51893848

Centisome position: 81.58

GC content: 54.31

Gene sequence:

>987_bases
GTGGTTGGTGGAGCTGGATACGTCGGCAGTCATGTTGTTCGGGCGCTGTTGGAGGCAGGTCATGAACCGGTTGTTTATGA
TAATCTCTCGACTGGACACATGGAGGCGGTATGCGATAGCGAAGTCATAATTGGCGATGTTGGTGATCGCGACAAACTGC
GGACAGTGTTGCAGGCACGGCGCTTCGATGGGGTCGTTCACTTGGCGGCCGCCAGCTTAGTGGCGGAGTCCATGCGGGAA
CCCTCGGTCTATTTTCGCAACAACGTGAGCGCTAGTATTGTGCTGTTTGATGAGCTGATTAGAGCTGACGTACCATGGGT
AGTCCTCTCCTCTACCGCAGCGGTATACGGAGAGCCTGAGGTGGTTCCCATTCCGGAAGAGCATCCCACCAGACCGACTA
ATCCTTATGGTGAATCGAAGTTGATGTTGGAGCGAATATTGAAGTGGTATGATGTGGCATATGGCTTCAAGCACATATCG
CTCCGATACTTTAACGCTGCCGGTGCTCACCCGTCAGGACAGATTGGAGAAGACCACATGCCAGAGACGCACCTCATCCC
CATCGTCTTGCAGGTCGCTCTCGGCTTACGGGATTTCGTAACTGTGTTTGGCATTGACTATCCCACTCCGGATGGTTCTG
CCGTTCGGGACTATGTTCATGTTTGTGATCTGGCCGATGCCCATGTGCGAGCTATCACCAGACTCTGTGCGACTGGGACC
AGTAGCGTCTATAACCTTGGTAGTGCGCGCGGGTACTCGGTTCGTGAGATTGTTGACGTGGCTCAGCAGGTTGTGGGGAT
GCCGATTAAGTCTGTGGTCGCCGACCGGCGGGCAGGTGACCCTCCTATTCTTGTGGCTGACAATCGAAAGGCGCTAAGCG
AGTTGCAGTGGATGCCGCAGTTTGACTTGGAGGCGATTGTTGAGACTGCTTGGCGGTGGCATCGCGACCACCCTCAGGGT
TATGGAAATAGGAGATCATCGATTTGA

Upstream 100 bases:

>100_bases
TATGAGCAGAGATTTACACTAGATCGAATGCTCGATCAGACGAGACGCATATACGAGTTGATAATCTCTTAGCTAGTAGG
TGATTTTTGTGAGGGTCTTG

Downstream 100 bases:

>100_bases
TGCTGTATGGTAGCCCGGTGGGAAGGGCATCCCTGGGAGGATAACCGGAAACGTTATGATAAGGGGGCACCCTCGGGAGT
CACGAATTGGGGCCATCCGC

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 328; Mature: 328

Protein sequence:

>328_residues
MVGGAGYVGSHVVRALLEAGHEPVVYDNLSTGHMEAVCDSEVIIGDVGDRDKLRTVLQARRFDGVVHLAAASLVAESMRE
PSVYFRNNVSASIVLFDELIRADVPWVVLSSTAAVYGEPEVVPIPEEHPTRPTNPYGESKLMLERILKWYDVAYGFKHIS
LRYFNAAGAHPSGQIGEDHMPETHLIPIVLQVALGLRDFVTVFGIDYPTPDGSAVRDYVHVCDLADAHVRAITRLCATGT
SSVYNLGSARGYSVREIVDVAQQVVGMPIKSVVADRRAGDPPILVADNRKALSELQWMPQFDLEAIVETAWRWHRDHPQG
YGNRRSSI

Sequences:

>Translated_328_residues
MVGGAGYVGSHVVRALLEAGHEPVVYDNLSTGHMEAVCDSEVIIGDVGDRDKLRTVLQARRFDGVVHLAAASLVAESMRE
PSVYFRNNVSASIVLFDELIRADVPWVVLSSTAAVYGEPEVVPIPEEHPTRPTNPYGESKLMLERILKWYDVAYGFKHIS
LRYFNAAGAHPSGQIGEDHMPETHLIPIVLQVALGLRDFVTVFGIDYPTPDGSAVRDYVHVCDLADAHVRAITRLCATGT
SSVYNLGSARGYSVREIVDVAQQVVGMPIKSVVADRRAGDPPILVADNRKALSELQWMPQFDLEAIVETAWRWHRDHPQG
YGNRRSSI
>Mature_328_residues
MVGGAGYVGSHVVRALLEAGHEPVVYDNLSTGHMEAVCDSEVIIGDVGDRDKLRTVLQARRFDGVVHLAAASLVAESMRE
PSVYFRNNVSASIVLFDELIRADVPWVVLSSTAAVYGEPEVVPIPEEHPTRPTNPYGESKLMLERILKWYDVAYGFKHIS
LRYFNAAGAHPSGQIGEDHMPETHLIPIVLQVALGLRDFVTVFGIDYPTPDGSAVRDYVHVCDLADAHVRAITRLCATGT
SSVYNLGSARGYSVREIVDVAQQVVGMPIKSVVADRRAGDPPILVADNRKALSELQWMPQFDLEAIVETAWRWHRDHPQG
YGNRRSSI

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=345, Percent_Identity=38.5507246376812, Blast_Score=233, Evalue=2e-61,
Organism=Homo sapiens, GI56118217, Length=345, Percent_Identity=38.5507246376812, Blast_Score=233, Evalue=2e-61,
Organism=Homo sapiens, GI189083684, Length=345, Percent_Identity=38.5507246376812, Blast_Score=233, Evalue=2e-61,
Organism=Homo sapiens, GI42516563, Length=337, Percent_Identity=26.7062314540059, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI7657641, Length=347, Percent_Identity=23.0547550432277, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI1786974, Length=334, Percent_Identity=39.5209580838323, Blast_Score=236, Evalue=2e-63,
Organism=Escherichia coli, GI48994969, Length=353, Percent_Identity=26.9121813031161, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI1788353, Length=369, Percent_Identity=26.5582655826558, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI1790049, Length=266, Percent_Identity=26.3157894736842, Blast_Score=71, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI71982035, Length=345, Percent_Identity=38.2608695652174, Blast_Score=219, Evalue=2e-57,
Organism=Caenorhabditis elegans, GI71982038, Length=347, Percent_Identity=38.0403458213257, Blast_Score=219, Evalue=2e-57,
Organism=Caenorhabditis elegans, GI17539532, Length=316, Percent_Identity=25.6329113924051, Blast_Score=86, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17568069, Length=266, Percent_Identity=26.3157894736842, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6319493, Length=340, Percent_Identity=38.8235294117647, Blast_Score=234, Evalue=2e-62,
Organism=Drosophila melanogaster, GI19923002, Length=345, Percent_Identity=39.7101449275362, Blast_Score=251, Evalue=7e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 36120; Mature: 36120

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVGGAGYVGSHVVRALLEAGHEPVVYDNLSTGHMEAVCDSEVIIGDVGDRDKLRTVLQAR
CCCCCCHHHHHHHHHHHHCCCCCEEECCCCCCCHHHHCCCCEEEECCCCHHHHHHHHHHH
RFDGVVHLAAASLVAESMREPSVYFRNNVSASIVLFDELIRADVPWVVLSSTAAVYGEPE
HHCCHHHHHHHHHHHHHHCCCCEEEECCCCEEHHHHHHHHHCCCCEEEEECCCCCCCCCC
VVPIPEEHPTRPTNPYGESKLMLERILKWYDVAYGFKHISLRYFNAAGAHPSGQIGEDHM
EEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCCCCCCCC
PETHLIPIVLQVALGLRDFVTVFGIDYPTPDGSAVRDYVHVCDLADAHVRAITRLCATGT
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCC
SSVYNLGSARGYSVREIVDVAQQVVGMPIKSVVADRRAGDPPILVADNRKALSELQWMPQ
HHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCEEEECCHHHHHHHHCCCC
FDLEAIVETAWRWHRDHPQGYGNRRSSI
CCHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MVGGAGYVGSHVVRALLEAGHEPVVYDNLSTGHMEAVCDSEVIIGDVGDRDKLRTVLQAR
CCCCCCHHHHHHHHHHHHCCCCCEEECCCCCCCHHHHCCCCEEEECCCCHHHHHHHHHHH
RFDGVVHLAAASLVAESMREPSVYFRNNVSASIVLFDELIRADVPWVVLSSTAAVYGEPE
HHCCHHHHHHHHHHHHHHCCCCEEEECCCCEEHHHHHHHHHCCCCEEEEECCCCCCCCCC
VVPIPEEHPTRPTNPYGESKLMLERILKWYDVAYGFKHISLRYFNAAGAHPSGQIGEDHM
EEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCCCCCCCC
PETHLIPIVLQVALGLRDFVTVFGIDYPTPDGSAVRDYVHVCDLADAHVRAITRLCATGT
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCC
SSVYNLGSARGYSVREIVDVAQQVVGMPIKSVVADRRAGDPPILVADNRKALSELQWMPQ
HHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCEEEECCHHHHHHHHCCCC
FDLEAIVETAWRWHRDHPQGYGNRRSSI
CCHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9603808 [H]