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The map label for this gene is obgE

Identifier: 51599032

GI number: 51599032

Start: 821408

End: 822397

Strand: Direct

Name: obgE

Synonym: BG0805

Alternate gene names: 51599032

Gene position: 821408-822397 (Clockwise)

Preceding gene: 51599031

Following gene: 51599033

Centisome position: 90.84

GC content: 34.04

Gene sequence:

>990_bases
TTGTATAACTTTAAAGACTCTGTAAGTATAACGGTAATTTCGGGCAATGGTGGTTCTGGGTGCGTTTCTTTTTTGCGAGA
AAAGTTTAATGCAAAGGGTGGTCCGGATGGCGGAAATGGCGGGAGCGGTGGGAGTGTAATTTTCAAGGTGAAAGAAAATC
TTCGCACTTTATCTTCTTATAAAAATGGCCATGTGCTTTGTGCCAAAAATGGTAGACCTGGAATGAGTTTTAAGAGAAGC
GGAGCTAATGGCAAAGATTTAATTCTTTTTGTTCCTCCAAATACGGACATTTATAATGAAAACGATGAAGCTCTTTTGTG
TAGGCTTGAAAAATTAAATGACGAATTTGTTATTTTAAAAGGTGGTAGAGGTGGTCTTGGTAATTGGAATTTTAAAACTT
CAATTAGAAGGGCGCCAAGGTTTGCTCAACCCGGAGAATCAGGCAATAGCTTAAATGTTCGTCTTGAACTTTTTTTGGTG
GCGGACATTGGGCTTGTTGGACCTCCTAATGCCGGCAAATCTTCTCTTCTTAATAGAATAACTTCAGCAAAATCTAGGGT
CGCAAATTATCCTTTTACAACAAAGATTCCCCATCTTGGTGTACTTAGATATTCTTATGATGATTTAATCATTGCAGATA
TTCCGGGAATAATTAAAGGTGCTAGCTTTGGAGTAGGGCTTGGGACTAAATTTTTAAAACATATTACTAAAACTAAAATT
TTAGCCTTAGTGATTGATATTTCTGAAGCAAATTTTTTAGAATCATATAACATTCTTTTGAATGAATTAAAATCTTATAG
CTATAAGCTTTTTAATAAAAAAAAAATTATTATTGCCAATAAGCTCGATTTGGACAGTTCTGAGAAAAATTTTAATTGCT
TGATAAAGGCCTTAGGAAAAGAAGAAAAGATTATCGGCATCTCTATTTATGAGAATAGAGGGATTGATGAACTTATTAAA
GAATTTTTTATTTTGGCTAAAGCTTTTTAA

Upstream 100 bases:

>100_bases
CTGGCAAGGTAGAGTTTAAAACTTTAAAGGGAAAAAAATATGTAAATATTATTTAGCATATAAATAATATTTTGGCTTTA
ATTGAAAAATTGGAGAAAGT

Downstream 100 bases:

>100_bases
TAAAATTGATTTTTATTGTGGGTTTTTTTGTTTTTAAGATTTGGTTTTTGGATGTCAAATTCATTTAATTTAGGGAAAAA
TAATTCATGAGAATTGCAAT

Product: GTPase ObgE

Products: NA

Alternate protein names: GTP-binding protein obg

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MYNFKDSVSITVISGNGGSGCVSFLREKFNAKGGPDGGNGGSGGSVIFKVKENLRTLSSYKNGHVLCAKNGRPGMSFKRS
GANGKDLILFVPPNTDIYNENDEALLCRLEKLNDEFVILKGGRGGLGNWNFKTSIRRAPRFAQPGESGNSLNVRLELFLV
ADIGLVGPPNAGKSSLLNRITSAKSRVANYPFTTKIPHLGVLRYSYDDLIIADIPGIIKGASFGVGLGTKFLKHITKTKI
LALVIDISEANFLESYNILLNELKSYSYKLFNKKKIIIANKLDLDSSEKNFNCLIKALGKEEKIIGISIYENRGIDELIK
EFFILAKAF

Sequences:

>Translated_329_residues
MYNFKDSVSITVISGNGGSGCVSFLREKFNAKGGPDGGNGGSGGSVIFKVKENLRTLSSYKNGHVLCAKNGRPGMSFKRS
GANGKDLILFVPPNTDIYNENDEALLCRLEKLNDEFVILKGGRGGLGNWNFKTSIRRAPRFAQPGESGNSLNVRLELFLV
ADIGLVGPPNAGKSSLLNRITSAKSRVANYPFTTKIPHLGVLRYSYDDLIIADIPGIIKGASFGVGLGTKFLKHITKTKI
LALVIDISEANFLESYNILLNELKSYSYKLFNKKKIIIANKLDLDSSEKNFNCLIKALGKEEKIIGISIYENRGIDELIK
EFFILAKAF
>Mature_329_residues
MYNFKDSVSITVISGNGGSGCVSFLREKFNAKGGPDGGNGGSGGSVIFKVKENLRTLSSYKNGHVLCAKNGRPGMSFKRS
GANGKDLILFVPPNTDIYNENDEALLCRLEKLNDEFVILKGGRGGLGNWNFKTSIRRAPRFAQPGESGNSLNVRLELFLV
ADIGLVGPPNAGKSSLLNRITSAKSRVANYPFTTKIPHLGVLRYSYDDLIIADIPGIIKGASFGVGLGTKFLKHITKTKI
LALVIDISEANFLESYNILLNELKSYSYKLFNKKKIIIANKLDLDSSEKNFNCLIKALGKEEKIIGISIYENRGIDELIK
EFFILAKAF

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain

Homologues:

Organism=Homo sapiens, GI24308117, Length=328, Percent_Identity=37.5, Blast_Score=157, Evalue=1e-38,
Organism=Homo sapiens, GI111955139, Length=252, Percent_Identity=35.3174603174603, Blast_Score=133, Evalue=3e-31,
Organism=Homo sapiens, GI111955063, Length=164, Percent_Identity=37.1951219512195, Blast_Score=102, Evalue=4e-22,
Organism=Escherichia coli, GI1789574, Length=322, Percent_Identity=40.6832298136646, Blast_Score=204, Evalue=5e-54,
Organism=Escherichia coli, GI1787454, Length=99, Percent_Identity=37.3737373737374, Blast_Score=62, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17508313, Length=323, Percent_Identity=36.2229102167183, Blast_Score=137, Evalue=6e-33,
Organism=Caenorhabditis elegans, GI17552324, Length=324, Percent_Identity=31.4814814814815, Blast_Score=126, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6321962, Length=163, Percent_Identity=39.8773006134969, Blast_Score=124, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6321612, Length=116, Percent_Identity=37.9310344827586, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6319281, Length=111, Percent_Identity=35.1351351351351, Blast_Score=67, Evalue=3e-12,
Organism=Drosophila melanogaster, GI20129375, Length=317, Percent_Identity=39.1167192429022, Blast_Score=179, Evalue=2e-45,
Organism=Drosophila melanogaster, GI24585318, Length=222, Percent_Identity=34.2342342342342, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI21356473, Length=123, Percent_Identity=34.1463414634146, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OBG_BORGA (Q65ZZ3)

Other databases:

- EMBL:   CP000013
- RefSeq:   YP_073220.1
- HSSP:   P44681
- ProteinModelPortal:   Q65ZZ3
- SMR:   Q65ZZ3
- EnsemblBacteria:   EBBORT00000007540
- GeneID:   2957458
- GenomeReviews:   CP000013_GR
- KEGG:   bga:BG0805
- GeneTree:   EBGT00050000006860
- HOGENOM:   HBG716038
- OMA:   ATCEHAG
- ProtClustDB:   PRK12299
- BioCyc:   BGAR290434:BG0805-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01454
- InterPro:   IPR014100
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:2.70.210.12
- PANTHER:   PTHR11702:SF3
- PIRSF:   PIRSF002401
- PRINTS:   PR00326
- TIGRFAMs:   TIGR02729
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF01018 GTP1_OBG; PF01926 MMR_HSR1; SSF82051 GTP1_OBG_sub

EC number: NA

Molecular weight: Translated: 35968; Mature: 35968

Theoretical pI: Translated: 10.08; Mature: 10.08

Prosite motif: PS00905 GTP1_OBG; PS00013 PROKAR_LIPOPROTEIN ; PS00095 C5_MTASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYNFKDSVSITVISGNGGSGCVSFLREKFNAKGGPDGGNGGSGGSVIFKVKENLRTLSSY
CCCCCCCEEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHC
KNGHVLCAKNGRPGMSFKRSGANGKDLILFVPPNTDIYNENDEALLCRLEKLNDEFVILK
CCCEEEEECCCCCCCCEEECCCCCCEEEEEECCCCCCCCCCCHHEEEEEECCCCCEEEEE
GGRGGLGNWNFKTSIRRAPRFAQPGESGNSLNVRLELFLVADIGLVGPPNAGKSSLLNRI
CCCCCCCCCCCHHHHHHCCCCCCCCCCCCEEEEEEEEEEEEECCCCCCCCCCHHHHHHHH
TSAKSRVANYPFTTKIPHLGVLRYSYDDLIIADIPGIIKGASFGVGLGTKFLKHITKTKI
HHHHHHHCCCCCCCCCCCCEEEEECCCCEEEECCCCHHCCCCCCCCHHHHHHHHHHHHEE
LALVIDISEANFLESYNILLNELKSYSYKLFNKKKIIIANKLDLDSSEKNFNCLIKALGK
EEEEEECCCCCHHHHHHHHHHHHHHHHEEEECCEEEEEEEECCCCCCCCCHHHHHHHCCC
EEKIIGISIYENRGIDELIKEFFILAKAF
CCEEEEEEEECCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MYNFKDSVSITVISGNGGSGCVSFLREKFNAKGGPDGGNGGSGGSVIFKVKENLRTLSSY
CCCCCCCEEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHC
KNGHVLCAKNGRPGMSFKRSGANGKDLILFVPPNTDIYNENDEALLCRLEKLNDEFVILK
CCCEEEEECCCCCCCCEEECCCCCCEEEEEECCCCCCCCCCCHHEEEEEECCCCCEEEEE
GGRGGLGNWNFKTSIRRAPRFAQPGESGNSLNVRLELFLVADIGLVGPPNAGKSSLLNRI
CCCCCCCCCCCHHHHHHCCCCCCCCCCCCEEEEEEEEEEEEECCCCCCCCCCHHHHHHHH
TSAKSRVANYPFTTKIPHLGVLRYSYDDLIIADIPGIIKGASFGVGLGTKFLKHITKTKI
HHHHHHHCCCCCCCCCCCCEEEEECCCCEEEECCCCHHCCCCCCCCHHHHHHHHHHHHEE
LALVIDISEANFLESYNILLNELKSYSYKLFNKKKIIIANKLDLDSSEKNFNCLIKALGK
EEEEEECCCCCHHHHHHHHHHHHHHHHEEEECCEEEEEEEECCCCCCCCCHHHHHHHCCC
EEKIIGISIYENRGIDELIKEFFILAKAF
CCEEEEEEEECCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA