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The map label for this gene is nth [H]

Identifier: 51598996

GI number: 51598996

Start: 791299

End: 791916

Strand: Direct

Name: nth [H]

Synonym: BG0768

Alternate gene names: 51598996

Gene position: 791299-791916 (Clockwise)

Preceding gene: 51598995

Following gene: 51599000

Centisome position: 87.51

GC content: 27.67

Gene sequence:

>618_bases
ATGATTAATCTTGATTTGATTGTTGATGAGACTTTGTTTAGATATCCCGATGTTAAACCCTTTCTAAATTATAAGAATAA
TTATGAACTTTTAATAATGGCGATTTTAAGTGCAAGAACAACAGATAATTTGGTAAATAAAATTTCTCCATATCTTTTTG
AAAGGTATGGGAATTTTGAAAGTTTATCAAGAGCAAATATGAGAGATGTTGAAAAATTAATTTATAAGACTGGTTTTTAT
TCAAGGAAAGCTAATAATATTGTAAATTGTTCTATTGATATTTTGGAAAAATTTAATGGTGTTATTCCAAATAATATTTT
TGATCTTGTTAAGCTACCCGGAGTAGGTCGAAAAACAGCAAATGTTATTCTTGGTGCTGTTTACAATAAGCCTGCAATTA
TTGTAGATACTCATTTTATCAGAGTTATTAAAAGGCATGCTATTTCTTTGGAAAATTCTCCTATTAAGATTGAACTGGAT
CTAAAAAGAAGAATAGAGTCTTGTAAACAGTATAGATTTTCTATGGCTATTAATAAGCATGGAAGAGAAGTTTGCACTGC
TAGAAATGTAAGTTGCGAGAATTGTTTTTTAGAAAAATTTTCTCCAAGAGTTTTTTAA

Upstream 100 bases:

>100_bases
GCATTTTAAATGCTAATGATGAGTATATCATTTTGAAAAATCCTTGTCAATAAGGTCTAGATACCTTTAATTTGTATATT
TTATGTTTTATAATTTTTTT

Downstream 100 bases:

>100_bases
TTTTTTTAGTTAAGATGATATTAAATGTTTCATTTTTTTTCTCAGTTGTAAATTTATTATTGCTAGTATTATGTTTATAC
CTATTAATATGAGTAGGGGA

Product: endonuclease III

Products: NA

Alternate protein names: DNA-(apurinic or apyrimidinic site) lyase [H]

Number of amino acids: Translated: 205; Mature: 205

Protein sequence:

>205_residues
MINLDLIVDETLFRYPDVKPFLNYKNNYELLIMAILSARTTDNLVNKISPYLFERYGNFESLSRANMRDVEKLIYKTGFY
SRKANNIVNCSIDILEKFNGVIPNNIFDLVKLPGVGRKTANVILGAVYNKPAIIVDTHFIRVIKRHAISLENSPIKIELD
LKRRIESCKQYRFSMAINKHGREVCTARNVSCENCFLEKFSPRVF

Sequences:

>Translated_205_residues
MINLDLIVDETLFRYPDVKPFLNYKNNYELLIMAILSARTTDNLVNKISPYLFERYGNFESLSRANMRDVEKLIYKTGFY
SRKANNIVNCSIDILEKFNGVIPNNIFDLVKLPGVGRKTANVILGAVYNKPAIIVDTHFIRVIKRHAISLENSPIKIELD
LKRRIESCKQYRFSMAINKHGREVCTARNVSCENCFLEKFSPRVF
>Mature_205_residues
MINLDLIVDETLFRYPDVKPFLNYKNNYELLIMAILSARTTDNLVNKISPYLFERYGNFESLSRANMRDVEKLIYKTGFY
SRKANNIVNCSIDILEKFNGVIPNNIFDLVKLPGVGRKTANVILGAVYNKPAIIVDTHFIRVIKRHAISLENSPIKIELD
LKRRIESCKQYRFSMAINKHGREVCTARNVSCENCFLEKFSPRVF

Specific function: Has both an apurinic and/or apyrimidinic endonuclease activity and a DNA N-glycosylase activity. Incises damaged DNA at cytosines, thymines and guanines. Acts on a damaged strand, 5' from the damaged site [H]

COG id: COG0177

COG function: function code L; Predicted EndoIII-related endonuclease

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Nth/MutY family [H]

Homologues:

Organism=Escherichia coli, GI1787920, Length=179, Percent_Identity=34.0782122905028, Blast_Score=105, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011257
- InterPro:   IPR004036
- InterPro:   IPR005759
- InterPro:   IPR004035
- InterPro:   IPR003651
- InterPro:   IPR003265
- InterPro:   IPR000445
- InterPro:   IPR003583
- InterPro:   IPR023170 [H]

Pfam domain/function: PF00633 HHH; PF00730 HhH-GPD [H]

EC number: =4.2.99.18 [H]

Molecular weight: Translated: 23747; Mature: 23747

Theoretical pI: Translated: 9.78; Mature: 9.78

Prosite motif: PS01155 ENDONUCLEASE_III_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINLDLIVDETLFRYPDVKPFLNYKNNYELLIMAILSARTTDNLVNKISPYLFERYGNFE
CEEEEEEECHHHHHCCCCCHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHH
SLSRANMRDVEKLIYKTGFYSRKANNIVNCSIDILEKFNGVIPNNIFDLVKLPGVGRKTA
HHHHCCHHHHHHHHHHHCCCCCCCCCEEECHHHHHHHCCCCCCCHHHHHHHCCCCCCHHH
NVILGAVYNKPAIIVDTHFIRVIKRHAISLENSPIKIELDLKRRIESCKQYRFSMAINKH
HHHEEHCCCCCEEEEHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHC
GREVCTARNVSCENCFLEKFSPRVF
CHHHHHHCCCCHHHHHHHHCCCCCC
>Mature Secondary Structure
MINLDLIVDETLFRYPDVKPFLNYKNNYELLIMAILSARTTDNLVNKISPYLFERYGNFE
CEEEEEEECHHHHHCCCCCHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHH
SLSRANMRDVEKLIYKTGFYSRKANNIVNCSIDILEKFNGVIPNNIFDLVKLPGVGRKTA
HHHHCCHHHHHHHHHHHCCCCCCCCCEEECHHHHHHHCCCCCCCHHHHHHHCCCCCCHHH
NVILGAVYNKPAIIVDTHFIRVIKRHAISLENSPIKIELDLKRRIESCKQYRFSMAINKH
HHHEEHCCCCCEEEEHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHC
GREVCTARNVSCENCFLEKFSPRVF
CHHHHHHCCCCHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]