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The map label for this gene is mcp-4 [H]

Identifier: 51598935

GI number: 51598935

Start: 720747

End: 723008

Strand: Direct

Name: mcp-4 [H]

Synonym: BG0703

Alternate gene names: 51598935

Gene position: 720747-723008 (Clockwise)

Preceding gene: 51598934

Following gene: 51598936

Centisome position: 79.71

GC content: 31.87

Gene sequence:

>2262_bases
ATGCTTGTGAAGCTTAAATACAGGTTTGTTGGATTTTTATTATTGTTTTTAATTTTTATACTGTTGCTTTTTTCTATGAT
TTTTAATTTTGTTTTATGTGGTTATTTAGAAGATTATTATAAGCAGCTTACAAGGGCGCAATTAAGAAGAGCAGCTTTTT
CTACGCAATCTTTTTTAGACACTTTGTATGTTATAATCAACGGTGCAGCTTCTAATTTAGCACTTGAAACCATATCAGAA
TTTGCAATTTCCGAGAATAGAGGAAAAGATTTCTCTGAGTCTGAATTGGTAGATTTAAGAAAAAATTCAAAATTTGTTAT
TGATTCTGTAAAGGTGAATAAAAAATATCGACAATACTTATACAATTTTATGACTAATCTTAAAAATGATACTCTTTTTG
AAGAATTCGCGTTTTTTGATTTTGAAGGGAGAATAATTGTTAGCACAAGGCATGAAAATAATATGGATTTTGGACATTCT
GAGGCCAATACTAATTATTTTAAAAAAGCGATTGAGGATTATAAGCAAAACCAATTAAAATTTATAGGCTGGTATTCAAA
TCTTTCTGAAGGAATATCTGCAGAAGTTGCCATTAGGTCTAGGCAAAGTGAAAAAAAGGCTTTTGCAATAATTGTGCCTG
TATACTCCCCAGAAGATAAGCTTGTTTGTGGATATTTGGCTGGATATTTGCTTAATGATGTTTTAGCAGATAGTTTTGAT
AGATTTAGATTTGGTTTTTATAAAAGGGGCAATTTTGTTTATATAGATTCTAATAATATAGCAGTTAATCCTTTTGAAGA
ATACAATGAAACCAGTAGGGTTAGTTCTAAATTTTTAAATATTCTTAAAGATGTTTTTTCTAAGCCACCTCTTTTATCAA
ATATTCCTACTGAAGTGTCGGTTTACACTATTGATAGGATATTATTCTCCGAAATGGGAGAAGAGTGTTATTATGCATTG
TTGCCCATAAGTAGTAAATTAGGAGAGAAAGGTGGGGTGCTTATTGCTAGACTTCCTTATAAAGATATTTACGGAGTAAT
ATCTAGTCTAAAATTTCAGTATATCTTGTATTCTGTTTTAGGCATTATTTCATTAAGCATTGTTCTTTTAATGAGAATAG
ATAGGATTATTAGTTTTCGTTTAAACGCAATTAGAGTTTTAGTTCAAGATATGGTCAAGGGAGATTTAGACAAAGATTAT
GCCCTTGATGATGGTGATGATTATTTTGATGAGCTTGGCATGTTAAGTCTTCAGGTTGTGAAAATGAAAAAAGCTATTTC
TGTAGCAATTGCTAGTGTTTTGAGAAATATTAGCTATGTAAATAAGGCAAGTTTAGAAGTTGCCAGTTCTAGTCAAAATT
TAACTTCTAGTGCGTTACAGCAGGCATCTGCTCTTGAAGAAATGTCAGCCAATGTTGAGCAAATAGCGTCAGGTGTTAAT
ATGAGCGCTAATAATTCTTATGAAACTGAGCAAATAGCTTTAAAGACCAATGAAAATTCTCAGATAGGTGGTAAAGCTGT
TGAAGAATCTGTTATTGCTATGCAAGATATTGTAGAGAAAGTTAGCGTTATTGAAGAAATAGCTAGAAAAACCAATTTAC
TTGCTTTGAATGCTGCTATTGAAGCTGCAAGAGCAGGTGATGAAGGAAAGGGATTTGCTGTTGTGGCTAGTGAGATTAGA
AAGTTGGCTGATCTTAGCAAAATTTCGGCTCTTGAGATTGGAGAGTTGGTTGAAGATAACTCTAAGGTAGCAACCGAAGC
TGGAGTGATCTTCAAAGAAATGTTACCTGAAATAGAAGAAACAGCTAATCTTGTCAAAAAAATTTCAGAAGGTAGCTCTA
AGCAGAGCGATCAAATTGCTCAATTTAAAATGGCTTTAGACCAGGTTGGAGAAGTTGTTCAGTCTTCAGCTTCAAGTAGT
GAGCAACTTTCTAGCATGTCTGATAAAATGTTAGAAAAGTCTAAGGAACTCAGAAAATCTGTATTATTTTTCAAAATTAA
AGATTCTAAGATTGAAAATCTGGAAGATGGTGATTATGATTTCAGGTTGATGGATTGTCCTGAAAATTCTTTTAAAGATG
AAAATCAAGATTTGAAAGGAAATGAAATCTCTACTTTAAATGGCAGTAGACATAGTAATTATTCTTTAAGTATTGAAAGC
GAGCCTTCTGCAAGAACTATTAATAAGCGGGTTGATCCTAAAAAAGCTATCGATATTGCTGATAAGGATTTAAATTTTGA
TGATGATTTTTCAGAGTTTTAG

Upstream 100 bases:

>100_bases
TTTAAGAGTTTTTAATTTTTTGCTGTAAATTTTTTTTAATACCCTTTTGGTCTTAAGTTTGTTTGATTAAATAAGTAGAT
GATTTGTGAGGTAGTTTATT

Downstream 100 bases:

>100_bases
AATTTTTTTTGTAAAAAGGGGTGGTTAGTATGAAGCTGAAAGCTAGGATGTTGCTACTTGTTCTTGTTCTTATAGCATTC
TTTATATCAATTTTGTTTTT

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: Citrate chemoreceptor protein [H]

Number of amino acids: Translated: 753; Mature: 753

Protein sequence:

>753_residues
MLVKLKYRFVGFLLLFLIFILLLFSMIFNFVLCGYLEDYYKQLTRAQLRRAAFSTQSFLDTLYVIINGAASNLALETISE
FAISENRGKDFSESELVDLRKNSKFVIDSVKVNKKYRQYLYNFMTNLKNDTLFEEFAFFDFEGRIIVSTRHENNMDFGHS
EANTNYFKKAIEDYKQNQLKFIGWYSNLSEGISAEVAIRSRQSEKKAFAIIVPVYSPEDKLVCGYLAGYLLNDVLADSFD
RFRFGFYKRGNFVYIDSNNIAVNPFEEYNETSRVSSKFLNILKDVFSKPPLLSNIPTEVSVYTIDRILFSEMGEECYYAL
LPISSKLGEKGGVLIARLPYKDIYGVISSLKFQYILYSVLGIISLSIVLLMRIDRIISFRLNAIRVLVQDMVKGDLDKDY
ALDDGDDYFDELGMLSLQVVKMKKAISVAIASVLRNISYVNKASLEVASSSQNLTSSALQQASALEEMSANVEQIASGVN
MSANNSYETEQIALKTNENSQIGGKAVEESVIAMQDIVEKVSVIEEIARKTNLLALNAAIEAARAGDEGKGFAVVASEIR
KLADLSKISALEIGELVEDNSKVATEAGVIFKEMLPEIEETANLVKKISEGSSKQSDQIAQFKMALDQVGEVVQSSASSS
EQLSSMSDKMLEKSKELRKSVLFFKIKDSKIENLEDGDYDFRLMDCPENSFKDENQDLKGNEISTLNGSRHSNYSLSIES
EPSARTINKRVDPKKAIDIADKDLNFDDDFSEF

Sequences:

>Translated_753_residues
MLVKLKYRFVGFLLLFLIFILLLFSMIFNFVLCGYLEDYYKQLTRAQLRRAAFSTQSFLDTLYVIINGAASNLALETISE
FAISENRGKDFSESELVDLRKNSKFVIDSVKVNKKYRQYLYNFMTNLKNDTLFEEFAFFDFEGRIIVSTRHENNMDFGHS
EANTNYFKKAIEDYKQNQLKFIGWYSNLSEGISAEVAIRSRQSEKKAFAIIVPVYSPEDKLVCGYLAGYLLNDVLADSFD
RFRFGFYKRGNFVYIDSNNIAVNPFEEYNETSRVSSKFLNILKDVFSKPPLLSNIPTEVSVYTIDRILFSEMGEECYYAL
LPISSKLGEKGGVLIARLPYKDIYGVISSLKFQYILYSVLGIISLSIVLLMRIDRIISFRLNAIRVLVQDMVKGDLDKDY
ALDDGDDYFDELGMLSLQVVKMKKAISVAIASVLRNISYVNKASLEVASSSQNLTSSALQQASALEEMSANVEQIASGVN
MSANNSYETEQIALKTNENSQIGGKAVEESVIAMQDIVEKVSVIEEIARKTNLLALNAAIEAARAGDEGKGFAVVASEIR
KLADLSKISALEIGELVEDNSKVATEAGVIFKEMLPEIEETANLVKKISEGSSKQSDQIAQFKMALDQVGEVVQSSASSS
EQLSSMSDKMLEKSKELRKSVLFFKIKDSKIENLEDGDYDFRLMDCPENSFKDENQDLKGNEISTLNGSRHSNYSLSIES
EPSARTINKRVDPKKAIDIADKDLNFDDDFSEF
>Mature_753_residues
MLVKLKYRFVGFLLLFLIFILLLFSMIFNFVLCGYLEDYYKQLTRAQLRRAAFSTQSFLDTLYVIINGAASNLALETISE
FAISENRGKDFSESELVDLRKNSKFVIDSVKVNKKYRQYLYNFMTNLKNDTLFEEFAFFDFEGRIIVSTRHENNMDFGHS
EANTNYFKKAIEDYKQNQLKFIGWYSNLSEGISAEVAIRSRQSEKKAFAIIVPVYSPEDKLVCGYLAGYLLNDVLADSFD
RFRFGFYKRGNFVYIDSNNIAVNPFEEYNETSRVSSKFLNILKDVFSKPPLLSNIPTEVSVYTIDRILFSEMGEECYYAL
LPISSKLGEKGGVLIARLPYKDIYGVISSLKFQYILYSVLGIISLSIVLLMRIDRIISFRLNAIRVLVQDMVKGDLDKDY
ALDDGDDYFDELGMLSLQVVKMKKAISVAIASVLRNISYVNKASLEVASSSQNLTSSALQQASALEEMSANVEQIASGVN
MSANNSYETEQIALKTNENSQIGGKAVEESVIAMQDIVEKVSVIEEIARKTNLLALNAAIEAARAGDEGKGFAVVASEIR
KLADLSKISALEIGELVEDNSKVATEAGVIFKEMLPEIEETANLVKKISEGSSKQSDQIAQFKMALDQVGEVVQSSASSS
EQLSSMSDKMLEKSKELRKSVLFFKIKDSKIENLEDGDYDFRLMDCPENSFKDENQDLKGNEISTLNGSRHSNYSLSIES
EPSARTINKRVDPKKAIDIADKDLNFDDDFSEF

Specific function: Acts as a receptor for citrate and mediates taxis away from phenol. Also mediates an attractant response to metal-citrate complexes [H]

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=315, Percent_Identity=31.7460317460317, Blast_Score=142, Evalue=6e-35,
Organism=Escherichia coli, GI2367378, Length=299, Percent_Identity=32.1070234113712, Blast_Score=140, Evalue=4e-34,
Organism=Escherichia coli, GI1787690, Length=328, Percent_Identity=28.6585365853659, Blast_Score=137, Evalue=3e-33,
Organism=Escherichia coli, GI1788194, Length=268, Percent_Identity=29.4776119402985, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1789453, Length=269, Percent_Identity=27.5092936802974, Blast_Score=103, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 84779; Mature: 84779

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVKLKYRFVGFLLLFLIFILLLFSMIFNFVLCGYLEDYYKQLTRAQLRRAAFSTQSFLD
CEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLYVIINGAASNLALETISEFAISENRGKDFSESELVDLRKNSKFVIDSVKVNKKYRQYL
HHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCEEEEHHHHHHHHHHHH
YNFMTNLKNDTLFEEFAFFDFEGRIIVSTRHENNMDFGHSEANTNYFKKAIEDYKQNQLK
HHHHHHCCCCHHHHHHHEEECCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCEE
FIGWYSNLSEGISAEVAIRSRQSEKKAFAIIVPVYSPEDKLVCGYLAGYLLNDVLADSFD
EEEEHHHHCCCCCHHHHHHHCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHH
RFRFGFYKRGNFVYIDSNNIAVNPFEEYNETSRVSSKFLNILKDVFSKPPLLSNIPTEVS
HHHHCEEECCCEEEEECCCEEECCHHHHCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEE
VYTIDRILFSEMGEECYYALLPISSKLGEKGGVLIARLPYKDIYGVISSLKFQYILYSVL
HHHHHHHHHHHHCHHHEEEEEECHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHH
GIISLSIVLLMRIDRIISFRLNAIRVLVQDMVKGDLDKDYALDDGDDYFDELGMLSLQVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHH
KMKKAISVAIASVLRNISYVNKASLEVASSSQNLTSSALQQASALEEMSANVEQIASGVN
HHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHCCHHHHHCCCC
MSANNSYETEQIALKTNENSQIGGKAVEESVIAMQDIVEKVSVIEEIARKTNLLALNAAI
CCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEHHHH
EAARAGDEGKGFAVVASEIRKLADLSKISALEIGELVEDNSKVATEAGVIFKEMLPEIEE
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
TANLVKKISEGSSKQSDQIAQFKMALDQVGEVVQSSASSSEQLSSMSDKMLEKSKELRKS
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
VLFFKIKDSKIENLEDGDYDFRLMDCPENSFKDENQDLKGNEISTLNGSRHSNYSLSIES
HEEEEEECCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCEEECCCCCCCCEEEEECC
EPSARTINKRVDPKKAIDIADKDLNFDDDFSEF
CCCHHHHHHCCCCHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLVKLKYRFVGFLLLFLIFILLLFSMIFNFVLCGYLEDYYKQLTRAQLRRAAFSTQSFLD
CEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLYVIINGAASNLALETISEFAISENRGKDFSESELVDLRKNSKFVIDSVKVNKKYRQYL
HHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCEEEEHHHHHHHHHHHH
YNFMTNLKNDTLFEEFAFFDFEGRIIVSTRHENNMDFGHSEANTNYFKKAIEDYKQNQLK
HHHHHHCCCCHHHHHHHEEECCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCEE
FIGWYSNLSEGISAEVAIRSRQSEKKAFAIIVPVYSPEDKLVCGYLAGYLLNDVLADSFD
EEEEHHHHCCCCCHHHHHHHCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHH
RFRFGFYKRGNFVYIDSNNIAVNPFEEYNETSRVSSKFLNILKDVFSKPPLLSNIPTEVS
HHHHCEEECCCEEEEECCCEEECCHHHHCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEE
VYTIDRILFSEMGEECYYALLPISSKLGEKGGVLIARLPYKDIYGVISSLKFQYILYSVL
HHHHHHHHHHHHCHHHEEEEEECHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHH
GIISLSIVLLMRIDRIISFRLNAIRVLVQDMVKGDLDKDYALDDGDDYFDELGMLSLQVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHH
KMKKAISVAIASVLRNISYVNKASLEVASSSQNLTSSALQQASALEEMSANVEQIASGVN
HHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHCCHHHHHCCCC
MSANNSYETEQIALKTNENSQIGGKAVEESVIAMQDIVEKVSVIEEIARKTNLLALNAAI
CCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEHHHH
EAARAGDEGKGFAVVASEIRKLADLSKISALEIGELVEDNSKVATEAGVIFKEMLPEIEE
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
TANLVKKISEGSSKQSDQIAQFKMALDQVGEVVQSSASSSEQLSSMSDKMLEKSKELRKS
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
VLFFKIKDSKIENLEDGDYDFRLMDCPENSFKDENQDLKGNEISTLNGSRHSNYSLSIES
HEEEEEECCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCEEECCCCCCCCEEEEECC
EPSARTINKRVDPKKAIDIADKDLNFDDDFSEF
CCCHHHHHHCCCCHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8419927; 11677609 [H]