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The map label for this gene is gpmA [H]

Identifier: 51598913

GI number: 51598913

Start: 699508

End: 700254

Strand: Direct

Name: gpmA [H]

Synonym: BG0681

Alternate gene names: 51598913

Gene position: 699508-700254 (Clockwise)

Preceding gene: 51598911

Following gene: 51598916

Centisome position: 77.36

GC content: 33.07

Gene sequence:

>747_bases
ATGTATAAATTAGTTTTAGTGAGGCATGGAGAGAGTGAATGGAACAAAGAAAATCTTTTTACTGGTTGGACAGATGTTAA
ACTTTCTGACAAGGGTATCAATGAGGCTTTAGAAGCAGGTTTGCTCCTAAAGCAAGAAGGCTATTCTTTTGATATTGCTT
TTAGTTCTTTATTGTCAAGGGCTAATGATACTTTAAATATTATTTTGCGAGAATTGGGGCAATCTTATATTAGTGTAAAA
AAAACCTGGAGATTAAATGAGAGGCACTATGGAGCTTTACAAGGTTTAAATAAGTCAGAAACAGCTGCAAAATATGGGGA
AGGTAAAGTTTTAATTTGGAGACGCAGTTATGATGTGCCCCCAATGTCTTTAGATGAGTCTGAAGATCGTCATCCAATAA
AAGATCCAAGATATAAATATATTCCTAAAAGGGAGCTTCCTTCAACAGAATGCCTTAAAGATACTGTTACAAGAGTTATT
CCTTATTGGACTGATGAGATTGCAAAAGAAGTTCTTGGGGGTAAAAAAGTTATTGTTGCTGCTCATGGCAATTCTTTAAG
AGCTCTTGTTAAATATCTTGATAATTTAAGCGAAGAAGATGTTTTAAAGCTTAACATTCCTACGGGTATTCCTTTAGTTT
ATGAATTAGATAAAGATTTAAATCCTATTAAACATTACTATTTAGGTGATGAAAGTAAGATTAAAAGTGCAATGGAATCT
GTTGCTAGTCAAGGAAAGTTAAAGTAA

Upstream 100 bases:

>100_bases
AAGTATATCATTGTTTAATTAAGATTGAAATCTTGACTAGATTTCGTGCTAATTTATAATTATTAGTATTAGTAAATAAA
ATAATATGCTAGGAGATTTT

Downstream 100 bases:

>100_bases
TAGTCTATTACTATTAAAGTGTTAATAAGCCGTATTTATGGCTTATTTTTTTTATCATTTTAAGGTTTAAATATATTTGC
TTACAATCTTTTCAAAGCGG

Product: phosphoglyceromutase

Products: NA

Alternate protein names: BPG-dependent PGAM; PGAM; Phosphoglyceromutase; dPGM [H]

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MYKLVLVRHGESEWNKENLFTGWTDVKLSDKGINEALEAGLLLKQEGYSFDIAFSSLLSRANDTLNIILRELGQSYISVK
KTWRLNERHYGALQGLNKSETAAKYGEGKVLIWRRSYDVPPMSLDESEDRHPIKDPRYKYIPKRELPSTECLKDTVTRVI
PYWTDEIAKEVLGGKKVIVAAHGNSLRALVKYLDNLSEEDVLKLNIPTGIPLVYELDKDLNPIKHYYLGDESKIKSAMES
VASQGKLK

Sequences:

>Translated_248_residues
MYKLVLVRHGESEWNKENLFTGWTDVKLSDKGINEALEAGLLLKQEGYSFDIAFSSLLSRANDTLNIILRELGQSYISVK
KTWRLNERHYGALQGLNKSETAAKYGEGKVLIWRRSYDVPPMSLDESEDRHPIKDPRYKYIPKRELPSTECLKDTVTRVI
PYWTDEIAKEVLGGKKVIVAAHGNSLRALVKYLDNLSEEDVLKLNIPTGIPLVYELDKDLNPIKHYYLGDESKIKSAMES
VASQGKLK
>Mature_248_residues
MYKLVLVRHGESEWNKENLFTGWTDVKLSDKGINEALEAGLLLKQEGYSFDIAFSSLLSRANDTLNIILRELGQSYISVK
KTWRLNERHYGALQGLNKSETAAKYGEGKVLIWRRSYDVPPMSLDESEDRHPIKDPRYKYIPKRELPSTECLKDTVTRVI
PYWTDEIAKEVLGGKKVIVAAHGNSLRALVKYLDNLSEEDVLKLNIPTGIPLVYELDKDLNPIKHYYLGDESKIKSAMES
VASQGKLK

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate [H]

COG id: COG0588

COG function: function code G; Phosphoglycerate mutase 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily [H]

Homologues:

Organism=Homo sapiens, GI4505753, Length=250, Percent_Identity=54.8, Blast_Score=273, Evalue=1e-73,
Organism=Homo sapiens, GI50593010, Length=253, Percent_Identity=51.3833992094862, Blast_Score=272, Evalue=2e-73,
Organism=Homo sapiens, GI71274132, Length=250, Percent_Identity=51.6, Blast_Score=254, Evalue=6e-68,
Organism=Homo sapiens, GI4502445, Length=255, Percent_Identity=47.0588235294118, Blast_Score=250, Evalue=1e-66,
Organism=Homo sapiens, GI40353764, Length=255, Percent_Identity=47.0588235294118, Blast_Score=250, Evalue=1e-66,
Organism=Homo sapiens, GI310129614, Length=162, Percent_Identity=53.0864197530864, Blast_Score=165, Evalue=4e-41,
Organism=Escherichia coli, GI1786970, Length=246, Percent_Identity=59.7560975609756, Blast_Score=303, Evalue=1e-83,
Organism=Saccharomyces cerevisiae, GI6322697, Length=246, Percent_Identity=54.0650406504065, Blast_Score=256, Evalue=2e-69,
Organism=Saccharomyces cerevisiae, GI6324516, Length=287, Percent_Identity=33.1010452961672, Blast_Score=149, Evalue=6e-37,
Organism=Saccharomyces cerevisiae, GI6320183, Length=299, Percent_Identity=32.1070234113712, Blast_Score=137, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6324857, Length=111, Percent_Identity=30.6306306306306, Blast_Score=62, Evalue=8e-11,
Organism=Drosophila melanogaster, GI85725270, Length=251, Percent_Identity=54.5816733067729, Blast_Score=276, Evalue=1e-74,
Organism=Drosophila melanogaster, GI85725272, Length=251, Percent_Identity=54.5816733067729, Blast_Score=276, Evalue=1e-74,
Organism=Drosophila melanogaster, GI24650981, Length=251, Percent_Identity=54.5816733067729, Blast_Score=276, Evalue=1e-74,
Organism=Drosophila melanogaster, GI24646216, Length=251, Percent_Identity=51.792828685259, Blast_Score=270, Evalue=5e-73,
Organism=Drosophila melanogaster, GI28571815, Length=249, Percent_Identity=40.1606425702811, Blast_Score=187, Evalue=5e-48,
Organism=Drosophila melanogaster, GI28571817, Length=249, Percent_Identity=40.1606425702811, Blast_Score=187, Evalue=6e-48,
Organism=Drosophila melanogaster, GI24648979, Length=249, Percent_Identity=40.1606425702811, Blast_Score=187, Evalue=7e-48,

Paralogues:

None

Copy number: 960 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR005952 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: =5.4.2.1 [H]

Molecular weight: Translated: 28258; Mature: 28258

Theoretical pI: Translated: 8.34; Mature: 8.34

Prosite motif: PS00175 PG_MUTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYKLVLVRHGESEWNKENLFTGWTDVKLSDKGINEALEAGLLLKQEGYSFDIAFSSLLSR
CEEEEEEECCCCCCCCCCCCCCCEEEEECCCCHHHHHHHCEEEECCCCEEHHHHHHHHHH
ANDTLNIILRELGQSYISVKKTWRLNERHYGALQGLNKSETAAKYGEGKVLIWRRSYDVP
CCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHCCCCCEEEEEECCCCC
PMSLDESEDRHPIKDPRYKYIPKRELPSTECLKDTVTRVIPYWTDEIAKEVLGGKKVIVA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCEEEEE
AHGNSLRALVKYLDNLSEEDVLKLNIPTGIPLVYELDKDLNPIKHYYLGDESKIKSAMES
ECCCHHHHHHHHHHCCCCCCEEEEECCCCCCEEEECCCCCCHHHHHCCCCHHHHHHHHHH
VASQGKLK
HHHCCCCC
>Mature Secondary Structure
MYKLVLVRHGESEWNKENLFTGWTDVKLSDKGINEALEAGLLLKQEGYSFDIAFSSLLSR
CEEEEEEECCCCCCCCCCCCCCCEEEEECCCCHHHHHHHCEEEECCCCEEHHHHHHHHHH
ANDTLNIILRELGQSYISVKKTWRLNERHYGALQGLNKSETAAKYGEGKVLIWRRSYDVP
CCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHCCCCCEEEEEECCCCC
PMSLDESEDRHPIKDPRYKYIPKRELPSTECLKDTVTRVIPYWTDEIAKEVLGGKKVIVA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCEEEEE
AHGNSLRALVKYLDNLSEEDVLKLNIPTGIPLVYELDKDLNPIKHYYLGDESKIKSAMES
ECCCHHHHHHHHHHCCCCCCEEEEECCCCCCEEEECCCCCCHHHHHCCCCHHHHHHHHHH
VASQGKLK
HHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA