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The map label for this gene is clpX [H]

Identifier: 51598864

GI number: 51598864

Start: 640493

End: 641800

Strand: Direct

Name: clpX [H]

Synonym: BG0628

Alternate gene names: 51598864

Gene position: 640493-641800 (Clockwise)

Preceding gene: 51598863

Following gene: 51598865

Centisome position: 70.83

GC content: 32.11

Gene sequence:

>1308_bases
TTGGTAAAAATTTTTATGGCAAGATTAAAAGGTCAAAAAGTAAAAGAATGTTCTTTTTGTGGACTTAGCGTTGCTGAGCT
TGGGGGCAATGTTGTTATATCTAATGGAGTAGCGATTTGTCCTGAATGTTCTAAAATATGTCACAATCTTTTTAAAGAAA
AGTTGAGCAATCCGCTAGATTCTAAATCCAATGGTTTGCCAACTCCCAAACAACTTAAAGATCATTTAGACATGCATGTT
GTTGGGCAAGAAGATGCAAAAAAAGTTTTGTCTGTGGCTGTTTATAACCATTATAAGAGAATATTGAAAAATAATAAATA
TGATAATGGCATTGAAATTGAAAAATCCAATATACTTTTGGTTGGGCCCACAGGCAGTGGTAAAACTTTGCTTGCAAAAA
CGTTAGCTGCAGAGATGAATGTGCCATTTGCAATAGCAGATGCTACGACTTTAACAGAAGCTGGATATGTTGGTGAAGAT
GTAGAAAATATTTTGCTTAAATTAATACATGCTGCTCATGGGGATGTTAGTCTGGCTGAGAAAGGGATTATTTATATAGA
CGAAATAGATAAAATTGCTAAAAAAAATGAAAACGTTTCAATAACAAGAGATGTTTCTGGAGAAGGGGTTCAGCAGGCTT
TGTTAAAGATAATTGAGGGCACTATTGCTAATGTTCCCCCAAGAGGTGGTAGAAAGCATCCTTATGAGGATACTATTGAA
ATTAATACTCAAAATATACTCTTTATATGTGGTGGCGCTTTTGTTGGGCTTGAAAATATTGTTAAGAATCGAATAAACAA
GAGTTCTATTGGGTTTTCAGCAATTGAAAAAAAGAATATAAGAGAGGACACTTCATTAAAGTATTTAGAAATGGAAGATT
TGATTAAATTTGGCTTGATACCAGAGTTTGTTGGTAGACTTCCTGTACATTCGTATCTTGAAAAGTTAAATAAAGAAGAT
TTGATGAGAATATTAGTTGATCCTCAAAATTCCATTATTAAGCAGTATTATCATATGTTTAAAATGGATAATGTTGAATT
GGTATTTGAAAAAGATGCTTTGGAATCAATTGTAGATGAAGCTATTCTAAAAAATACTGGGGCAAGGGGTCTTAGATCTA
TTTTAGAGGGTCTTCTTAAAGATGTTATGTTTGAGGTTCCTTCAATTAGTAAGACTAAGAAGGTTATTGTTACAAAAGAA
TCTGTTTTAAATACAGATATTAACCCATTAATTTTGGTGGGAAATGCAATTAAAAAGCCTTGGGCAAAAGAGTTATATGA
AATCAATCTTAAATATGATAAAAAATAG

Upstream 100 bases:

>100_bases
AACTGGCTCTTGATATGGAAAGAGATTATTTTATGACTTCAAATGATGCTCTTAAATATGGTCTTATTGATAGTATCTTA
GTACGGGAGTAGTTTTATTT

Downstream 100 bases:

>100_bases
AAAAGAAGATCTTCCAATTGTTATTTTAAAAGAAAATGTTCTTTTCCCTAATATTACATTGTGGGTAACCTTTGATAATG
AATATGTAATTAATTCCATA

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 435; Mature: 435

Protein sequence:

>435_residues
MVKIFMARLKGQKVKECSFCGLSVAELGGNVVISNGVAICPECSKICHNLFKEKLSNPLDSKSNGLPTPKQLKDHLDMHV
VGQEDAKKVLSVAVYNHYKRILKNNKYDNGIEIEKSNILLVGPTGSGKTLLAKTLAAEMNVPFAIADATTLTEAGYVGED
VENILLKLIHAAHGDVSLAEKGIIYIDEIDKIAKKNENVSITRDVSGEGVQQALLKIIEGTIANVPPRGGRKHPYEDTIE
INTQNILFICGGAFVGLENIVKNRINKSSIGFSAIEKKNIREDTSLKYLEMEDLIKFGLIPEFVGRLPVHSYLEKLNKED
LMRILVDPQNSIIKQYYHMFKMDNVELVFEKDALESIVDEAILKNTGARGLRSILEGLLKDVMFEVPSISKTKKVIVTKE
SVLNTDINPLILVGNAIKKPWAKELYEINLKYDKK

Sequences:

>Translated_435_residues
MVKIFMARLKGQKVKECSFCGLSVAELGGNVVISNGVAICPECSKICHNLFKEKLSNPLDSKSNGLPTPKQLKDHLDMHV
VGQEDAKKVLSVAVYNHYKRILKNNKYDNGIEIEKSNILLVGPTGSGKTLLAKTLAAEMNVPFAIADATTLTEAGYVGED
VENILLKLIHAAHGDVSLAEKGIIYIDEIDKIAKKNENVSITRDVSGEGVQQALLKIIEGTIANVPPRGGRKHPYEDTIE
INTQNILFICGGAFVGLENIVKNRINKSSIGFSAIEKKNIREDTSLKYLEMEDLIKFGLIPEFVGRLPVHSYLEKLNKED
LMRILVDPQNSIIKQYYHMFKMDNVELVFEKDALESIVDEAILKNTGARGLRSILEGLLKDVMFEVPSISKTKKVIVTKE
SVLNTDINPLILVGNAIKKPWAKELYEINLKYDKK
>Mature_435_residues
MVKIFMARLKGQKVKECSFCGLSVAELGGNVVISNGVAICPECSKICHNLFKEKLSNPLDSKSNGLPTPKQLKDHLDMHV
VGQEDAKKVLSVAVYNHYKRILKNNKYDNGIEIEKSNILLVGPTGSGKTLLAKTLAAEMNVPFAIADATTLTEAGYVGED
VENILLKLIHAAHGDVSLAEKGIIYIDEIDKIAKKNENVSITRDVSGEGVQQALLKIIEGTIANVPPRGGRKHPYEDTIE
INTQNILFICGGAFVGLENIVKNRINKSSIGFSAIEKKNIREDTSLKYLEMEDLIKFGLIPEFVGRLPVHSYLEKLNKED
LMRILVDPQNSIIKQYYHMFKMDNVELVFEKDALESIVDEAILKNTGARGLRSILEGLLKDVMFEVPSISKTKKVIVTKE
SVLNTDINPLILVGNAIKKPWAKELYEINLKYDKK

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=308, Percent_Identity=48.0519480519481, Blast_Score=275, Evalue=7e-74,
Organism=Escherichia coli, GI1786642, Length=414, Percent_Identity=53.1400966183575, Blast_Score=433, Evalue=1e-122,
Organism=Escherichia coli, GI1790366, Length=105, Percent_Identity=40.9523809523809, Blast_Score=93, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI71982908, Length=312, Percent_Identity=44.5512820512821, Blast_Score=263, Evalue=9e-71,
Organism=Caenorhabditis elegans, GI71982905, Length=312, Percent_Identity=44.5512820512821, Blast_Score=263, Evalue=1e-70,
Organism=Caenorhabditis elegans, GI71988663, Length=405, Percent_Identity=36.7901234567901, Blast_Score=234, Evalue=8e-62,
Organism=Caenorhabditis elegans, GI71988660, Length=250, Percent_Identity=37.6, Blast_Score=166, Evalue=3e-41,
Organism=Saccharomyces cerevisiae, GI6319704, Length=414, Percent_Identity=39.1304347826087, Blast_Score=256, Evalue=5e-69,
Organism=Drosophila melanogaster, GI24648291, Length=315, Percent_Identity=42.8571428571429, Blast_Score=268, Evalue=4e-72,
Organism=Drosophila melanogaster, GI24648289, Length=315, Percent_Identity=42.8571428571429, Blast_Score=268, Evalue=6e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR002078
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 48313; Mature: 48313

Theoretical pI: Translated: 8.12; Mature: 8.12

Prosite motif: PS00676 SIGMA54_INTERACT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKIFMARLKGQKVKECSFCGLSVAELGGNVVISNGVAICPECSKICHNLFKEKLSNPLD
CCEEEEEHHCCCCCCHHHHCCCCHHHCCCCEEEECCEEECCHHHHHHHHHHHHHHCCCCC
SKSNGLPTPKQLKDHLDMHVVGQEDAKKVLSVAVYNHYKRILKNNKYDNGIEIEKSNILL
CCCCCCCCHHHHHHCCCEEEECHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCEEE
VGPTGSGKTLLAKTLAAEMNVPFAIADATTLTEAGYVGEDVENILLKLIHAAHGDVSLAE
EECCCCCCHHHHHHHHHHCCCCEEEECCHHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHC
KGIIYIDEIDKIAKKNENVSITRDVSGEGVQQALLKIIEGTIANVPPRGGRKHPYEDTIE
CCCEEEHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEE
INTQNILFICGGAFVGLENIVKNRINKSSIGFSAIEKKNIREDTSLKYLEMEDLIKFGLI
ECCCEEEEEECCHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCEEEECHHHHHHHCCC
PEFVGRLPVHSYLEKLNKEDLMRILVDPQNSIIKQYYHMFKMDNVELVFEKDALESIVDE
HHHHHCCCHHHHHHHHCHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHH
AILKNTGARGLRSILEGLLKDVMFEVPSISKTKKVIVTKESVLNTDINPLILVGNAIKKP
HHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHCCCCCCEEEECCHHCCH
WAKELYEINLKYDKK
HHHHHHEEEEEECCC
>Mature Secondary Structure
MVKIFMARLKGQKVKECSFCGLSVAELGGNVVISNGVAICPECSKICHNLFKEKLSNPLD
CCEEEEEHHCCCCCCHHHHCCCCHHHCCCCEEEECCEEECCHHHHHHHHHHHHHHCCCCC
SKSNGLPTPKQLKDHLDMHVVGQEDAKKVLSVAVYNHYKRILKNNKYDNGIEIEKSNILL
CCCCCCCCHHHHHHCCCEEEECHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCEEE
VGPTGSGKTLLAKTLAAEMNVPFAIADATTLTEAGYVGEDVENILLKLIHAAHGDVSLAE
EECCCCCCHHHHHHHHHHCCCCEEEECCHHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHC
KGIIYIDEIDKIAKKNENVSITRDVSGEGVQQALLKIIEGTIANVPPRGGRKHPYEDTIE
CCCEEEHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEE
INTQNILFICGGAFVGLENIVKNRINKSSIGFSAIEKKNIREDTSLKYLEMEDLIKFGLI
ECCCEEEEEECCHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCEEEECHHHHHHHCCC
PEFVGRLPVHSYLEKLNKEDLMRILVDPQNSIIKQYYHMFKMDNVELVFEKDALESIVDE
HHHHHCCCHHHHHHHHCHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHH
AILKNTGARGLRSILEGLLKDVMFEVPSISKTKKVIVTKESVLNTDINPLILVGNAIKKP
HHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHCCCCCCEEEECCHHCCH
WAKELYEINLKYDKK
HHHHHHEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9403685 [H]