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The map label for this gene is insK [H]

Identifier: 51598184

GI number: 51598184

Start: 4654550

End: 4655335

Strand: Direct

Name: insK [H]

Synonym: YPTB3899

Alternate gene names: 51598184

Gene position: 4654550-4655335 (Clockwise)

Preceding gene: 51598183

Following gene: 51598187

Centisome position: 98.1

GC content: 46.31

Gene sequence:

>786_bases
TTGGCACGCAGTACATACTATTATCATGCATCGAAACCGGACGGTGTAATTGATGACTATGCAGATGCGGTAAAAGCGAT
TGGCGCCCTAAGCAGACGACACGCACAGCGCTACGGTTATCGCCGGATGACGGTCGCACTGAGAAAAGAAGGGTTCACAC
TGAATCACAAAACGGTGCGAAAACTGATGAATCAGCACGGGTTACTCAGCCTCATTCAGCGGAAAAAATATCGCTCCTAT
AGGGCCGATGGTGGCCGGGCATCCGATAATCTATTGGCTCGTAATTTTACATCCGAAATCAGTGGATTGAAGTGGTGTAC
AGATGTCACAGAGTTCCGAGTTGGAGCACAGAAGCTGTATTTGTCGGTGATACAAGACCTGTTTAATAATGAGATTATTT
CTTGGCATATGTCAGAAAGAGCAGCATTAATCCTGACGTGCAAGACGCTGGAAAAAGCGCTGAAAGTGAAAGGGAGAAAA
GAAGGCCTGATGTTGCACAGCGATCAGGGCTGGCATTACCGAACGCCGATGTGGCGCTCAATGCTTGTCGAGGCGGGGAT
AAGGCAAAGTATGTCACGCAAAGGCAATTGTTTAGATAATGCAGTGATGGAAAATTTCTTCAGTCACCTGAAAGCCGAGA
TGTATCACCGTAAGAAGTACGATTCAGCCACAGTTTTAAAGCGTGACATTGTAGAATATATCCATTATTACAATACAGAG
CGCATTAGCCTGAAAACAGGCGGAATGAGTCCGGCAGAATACCGGACTCAGGTAGAAAAGCAGTAA

Upstream 100 bases:

>100_bases
TGAGAGAAGAAAAGGCACTCAGGGAGCAGCAGAAAAAACCAGAATAGTTCAAGCACTGACAGCAGAACATCGACTTTCTT
GCCTACTGTGTGCCGCAAAA

Downstream 100 bases:

>100_bases
AGCAGATGTCCAAGTTTTGGGGTTCAGTGCACTTATGGCCCCATTGGCGGTTGGTTCATCGGAGGCCAGGTAAGCCGTAA
AGTCATAACAACCGAACCCG

Product: IS1661 transposase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 261; Mature: 260

Protein sequence:

>261_residues
MARSTYYYHASKPDGVIDDYADAVKAIGALSRRHAQRYGYRRMTVALRKEGFTLNHKTVRKLMNQHGLLSLIQRKKYRSY
RADGGRASDNLLARNFTSEISGLKWCTDVTEFRVGAQKLYLSVIQDLFNNEIISWHMSERAALILTCKTLEKALKVKGRK
EGLMLHSDQGWHYRTPMWRSMLVEAGIRQSMSRKGNCLDNAVMENFFSHLKAEMYHRKKYDSATVLKRDIVEYIHYYNTE
RISLKTGGMSPAEYRTQVEKQ

Sequences:

>Translated_261_residues
MARSTYYYHASKPDGVIDDYADAVKAIGALSRRHAQRYGYRRMTVALRKEGFTLNHKTVRKLMNQHGLLSLIQRKKYRSY
RADGGRASDNLLARNFTSEISGLKWCTDVTEFRVGAQKLYLSVIQDLFNNEIISWHMSERAALILTCKTLEKALKVKGRK
EGLMLHSDQGWHYRTPMWRSMLVEAGIRQSMSRKGNCLDNAVMENFFSHLKAEMYHRKKYDSATVLKRDIVEYIHYYNTE
RISLKTGGMSPAEYRTQVEKQ
>Mature_260_residues
ARSTYYYHASKPDGVIDDYADAVKAIGALSRRHAQRYGYRRMTVALRKEGFTLNHKTVRKLMNQHGLLSLIQRKKYRSYR
ADGGRASDNLLARNFTSEISGLKWCTDVTEFRVGAQKLYLSVIQDLFNNEIISWHMSERAALILTCKTLEKALKVKGRKE
GLMLHSDQGWHYRTPMWRSMLVEAGIRQSMSRKGNCLDNAVMENFFSHLKAEMYHRKKYDSATVLKRDIVEYIHYYNTER
ISLKTGGMSPAEYRTQVEKQ

Specific function: Involved in the transposition of the insertion sequence IS150 [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=231, Percent_Identity=28.1385281385281, Blast_Score=90, Evalue=2e-18,
Organism=Escherichia coli, GI1789981, Length=260, Percent_Identity=48.0769230769231, Blast_Score=247, Evalue=4e-67,
Organism=Escherichia coli, GI1788405, Length=224, Percent_Identity=36.6071428571429, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1787263, Length=224, Percent_Identity=36.6071428571429, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1786753, Length=224, Percent_Identity=36.6071428571429, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1786570, Length=224, Percent_Identity=36.6071428571429, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1786490, Length=224, Percent_Identity=36.6071428571429, Blast_Score=142, Evalue=2e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 30362; Mature: 30231

Theoretical pI: Translated: 10.30; Mature: 10.30

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARSTYYYHASKPDGVIDDYADAVKAIGALSRRHAQRYGYRRMTVALRKEGFTLNHKTVR
CCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCHHHHH
KLMNQHGLLSLIQRKKYRSYRADGGRASDNLLARNFTSEISGLKWCTDVTEFRVGAQKLY
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
LSVIQDLFNNEIISWHMSERAALILTCKTLEKALKVKGRKEGLMLHSDQGWHYRTPMWRS
HHHHHHHHCCCEEEEECCCCEEEEEEHHHHHHHHHHCCCCCCEEEECCCCCEECCHHHHH
MLVEAGIRQSMSRKGNCLDNAVMENFFSHLKAEMYHRKKYDSATVLKRDIVEYIHYYNTE
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCC
RISLKTGGMSPAEYRTQVEKQ
EEEEECCCCCHHHHHHHHCCC
>Mature Secondary Structure 
ARSTYYYHASKPDGVIDDYADAVKAIGALSRRHAQRYGYRRMTVALRKEGFTLNHKTVR
CCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCHHHHH
KLMNQHGLLSLIQRKKYRSYRADGGRASDNLLARNFTSEISGLKWCTDVTEFRVGAQKLY
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
LSVIQDLFNNEIISWHMSERAALILTCKTLEKALKVKGRKEGLMLHSDQGWHYRTPMWRS
HHHHHHHHCCCEEEEECCCCEEEEEEHHHHHHHHHHCCCCCCEEEECCCCCEECCHHHHH
MLVEAGIRQSMSRKGNCLDNAVMENFFSHLKAEMYHRKKYDSATVLKRDIVEYIHYYNTE
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCC
RISLKTGGMSPAEYRTQVEKQ
EEEEECCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2841644; 2541046; 8041620; 9278503 [H]