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The map label for this gene is uspA

Identifier: 51598102

GI number: 51598102

Start: 4546447

End: 4546893

Strand: Direct

Name: uspA

Synonym: YPTB3812

Alternate gene names: 51598102

Gene position: 4546447-4546893 (Clockwise)

Preceding gene: 51598100

Following gene: 51598103

Centisome position: 95.82

GC content: 46.31

Gene sequence:

>447_bases
ATGGCTTACAAACACATTCTGATTGCGGTTGACCTATCCCCGGAAAGCAAGGTATTGGTGGAAAAGGCGGTTTCCATGGC
CAAACCGTACAATGCCAAAGTTTCCCTGATCCATGTTGACGTTAACTACTCAGATCTCTATACCGGTCTGATTGACGTTA
ATCTCGGCGATATGCAGAAGCGTATTTCTGAAGAAACACACAATGCATTGACCGAGCTATCACAAAATGCAGGCTACCCC
GTTGAGCAAACGTTAAGCGGCAGCGGTGATCTAGGCCAGGTTCTGGTTGATGCCATTAAGAAATATGATATTGACTTGGT
CTTGTGTGGTCATCATCAGGATTTCTGGAGCAAGCTGATGTCTTCAGCGCGCCAACTGATCAATACCGTGCATGTCGATA
TGCTTATTGTGCCATTGCGCGATGACGAAAATGGCGAAGACGACTAA

Upstream 100 bases:

>100_bases
TAGAGGTCATAATGATGCGATATAAATGTCAGGCTAGTGCCCATTCGGTAGGTTGAGTGTTTGCTTACACATTAATTAAC
ATTATGGTAGGAGTTTACTT

Downstream 100 bases:

>100_bases
ATCTTCCCGTTGTTAGGTAACGCTAAACGCTCGCCTCTCCGGCGGGCGTTTTTGTGATAGACGTCTTGCCAGCCCTCCTC
GTTACCCTCAATCTGAATCC

Product: universal stress protein A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 148; Mature: 147

Protein sequence:

>148_residues
MAYKHILIAVDLSPESKVLVEKAVSMAKPYNAKVSLIHVDVNYSDLYTGLIDVNLGDMQKRISEETHNALTELSQNAGYP
VEQTLSGSGDLGQVLVDAIKKYDIDLVLCGHHQDFWSKLMSSARQLINTVHVDMLIVPLRDDENGEDD

Sequences:

>Translated_148_residues
MAYKHILIAVDLSPESKVLVEKAVSMAKPYNAKVSLIHVDVNYSDLYTGLIDVNLGDMQKRISEETHNALTELSQNAGYP
VEQTLSGSGDLGQVLVDAIKKYDIDLVLCGHHQDFWSKLMSSARQLINTVHVDMLIVPLRDDENGEDD
>Mature_147_residues
AYKHILIAVDLSPESKVLVEKAVSMAKPYNAKVSLIHVDVNYSDLYTGLIDVNLGDMQKRISEETHNALTELSQNAGYPV
EQTLSGSGDLGQVLVDAIKKYDIDLVLCGHHQDFWSKLMSSARQLINTVHVDMLIVPLRDDENGEDD

Specific function: Required for resistance to DNA-damaging agents

COG id: COG0589

COG function: function code T; Universal stress protein UspA and related nucleotide-binding proteins

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the universal stress protein A family

Homologues:

Organism=Escherichia coli, GI1789909, Length=143, Percent_Identity=93.7062937062937, Blast_Score=278, Evalue=1e-76,
Organism=Escherichia coli, GI1788205, Length=143, Percent_Identity=39.1608391608392, Blast_Score=106, Evalue=7e-25,
Organism=Escherichia coli, GI1790358, Length=141, Percent_Identity=34.7517730496454, Blast_Score=99, Evalue=1e-22,

Paralogues:

None

Copy number: 1660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 290 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 4003 Molecules/Cell In: Growth Phase, G

Swissprot (AC and ID): USPA_YERPE (Q8ZA49)

Other databases:

- EMBL:   AL590842
- EMBL:   AE009952
- EMBL:   AE017042
- PIR:   AD0483
- RefSeq:   NP_671153.1
- RefSeq:   NP_994621.1
- RefSeq:   YP_002348841.1
- ProteinModelPortal:   Q8ZA49
- SMR:   Q8ZA49
- GeneID:   1148806
- GeneID:   1176809
- GeneID:   2767048
- GenomeReviews:   AE009952_GR
- GenomeReviews:   AE017042_GR
- GenomeReviews:   AL590842_GR
- KEGG:   ype:YPO3970
- KEGG:   ypk:y3859
- KEGG:   ypm:YP_3333
- HOGENOM:   HBG733992
- OMA:   SMQDRIS
- ProtClustDB:   PRK15118
- BioCyc:   YPES187410:Y3859-MONOMER
- BioCyc:   YPES214092:YPO3970-MONOMER
- GO:   GO:0005737
- InterPro:   IPR014729
- InterPro:   IPR006016
- Gene3D:   G3DSA:3.40.50.620

Pfam domain/function: PF00582 Usp

EC number: NA

Molecular weight: Translated: 16439; Mature: 16308

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYKHILIAVDLSPESKVLVEKAVSMAKPYNAKVSLIHVDVNYSDLYTGLIDVNLGDMQK
CCCCEEEEEEECCCCHHHHHHHHHHHCCCCCCEEEEEEEECCHHHHHHEEEECCHHHHHH
RISEETHNALTELSQNAGYPVEQTLSGSGDLGQVLVDAIKKYDIDLVLCGHHQDFWSKLM
HHHHHHHHHHHHHHHCCCCCHHHHCCCCCCHHHHHHHHHHHCCCEEEEECCCHHHHHHHH
SSARQLINTVHVDMLIVPLRDDENGEDD
HHHHHHHHHHEEEEEEEECCCCCCCCCC
>Mature Secondary Structure 
AYKHILIAVDLSPESKVLVEKAVSMAKPYNAKVSLIHVDVNYSDLYTGLIDVNLGDMQK
CCCEEEEEEECCCCHHHHHHHHHHHCCCCCCEEEEEEEECCHHHHHHEEEECCHHHHHH
RISEETHNALTELSQNAGYPVEQTLSGSGDLGQVLVDAIKKYDIDLVLCGHHQDFWSKLM
HHHHHHHHHHHHHHHCCCCCHHHHCCCCCCHHHHHHHHHHHCCCEEEEECCCHHHHHHHH
SSARQLINTVHVDMLIVPLRDDENGEDD
HHHHHHHHHHEEEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430