Click here to switch to the map view.

The map label for this gene is arcA [H]

Identifier: 51598091

GI number: 51598091

Start: 4532419

End: 4533138

Strand: Direct

Name: arcA [H]

Synonym: YPTB3801

Alternate gene names: 51598091

Gene position: 4532419-4533138 (Clockwise)

Preceding gene: 51598090

Following gene: 51598098

Centisome position: 95.53

GC content: 51.11

Gene sequence:

>720_bases
ATGAAACCTGCAATCCTCGTGGTGGATGACGATACGGCCATCTGTGAAGTGCTGCGAGATGTACTTAACGAACACGTATT
CGATGTACTGTTATGCCACAGCGGCAATGAGGCGCTTCAGATTACCGCTACACAGCCCTCAATCGCACTTATTTTGCTTG
ATATGATGCTGCCGGATATCAATGGCCTGTTGGTGTTGCAGCAAGTGCAAAAACTGCGCCCGTCGCTACCGGTCGTGATG
CTCACCGGCATGGGTAGTGAGTCTGATATGGTGGTTGGGCTAGAAATGGGGGCGGACGACTATATCGCTAAACCATTTAA
TGCCAGGGTAGTGGTCGCACGCGTTAAAGCGGTGTTGCGGCGGAGCGAGGTGTTGGCGATAGAAAGTAGCAGTGTGAAAG
CCTGCGGATTGCAATTTAATGGCTGGCGGCTGAATACCGACCGCTGTCAGTTGATGAACCCACAGCAGCAGCAAATCGAT
TTGACTCAGGGGGAATATGGCCTGCTGCTGTCGTTGATGCAAAACGCCAGAAAAGTGCTCTCTCGTGAAAAGCTGCTTGA
ACTGACGCACCGTGAAAGCCTGGACGTTTTTGATCGCACTATTGATGTACTGATTATGCGGTTACGTCGAAAAATAGAAG
TTAATCCGCACCAGCCCACACTGATCCGTACCATCCGCGGCGTGGGGTATGTCTTTGCCGCCGATATTATTCATGCCTAG

Upstream 100 bases:

>100_bases
TGACAGCAGTTGAAAATTCAACACAGCTCGGTGTCATTTATACGGCTGGCAATCAACAATCGGATACACTTGTCAACACC
CCTCACCTCTGGAAAAAATA

Downstream 100 bases:

>100_bases
AATAATGTGGCCTAATAAGATGGGGCTTAAGACGCTCTCCCCATCGGGCTATCTTATGCGCGGTAATGGCTTATTTAACG
GTTCTCACGAATAAACACGT

Product: response regulator protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 239; Mature: 239

Protein sequence:

>239_residues
MKPAILVVDDDTAICEVLRDVLNEHVFDVLLCHSGNEALQITATQPSIALILLDMMLPDINGLLVLQQVQKLRPSLPVVM
LTGMGSESDMVVGLEMGADDYIAKPFNARVVVARVKAVLRRSEVLAIESSSVKACGLQFNGWRLNTDRCQLMNPQQQQID
LTQGEYGLLLSLMQNARKVLSREKLLELTHRESLDVFDRTIDVLIMRLRRKIEVNPHQPTLIRTIRGVGYVFAADIIHA

Sequences:

>Translated_239_residues
MKPAILVVDDDTAICEVLRDVLNEHVFDVLLCHSGNEALQITATQPSIALILLDMMLPDINGLLVLQQVQKLRPSLPVVM
LTGMGSESDMVVGLEMGADDYIAKPFNARVVVARVKAVLRRSEVLAIESSSVKACGLQFNGWRLNTDRCQLMNPQQQQID
LTQGEYGLLLSLMQNARKVLSREKLLELTHRESLDVFDRTIDVLIMRLRRKIEVNPHQPTLIRTIRGVGYVFAADIIHA
>Mature_239_residues
MKPAILVVDDDTAICEVLRDVLNEHVFDVLLCHSGNEALQITATQPSIALILLDMMLPDINGLLVLQQVQKLRPSLPVVM
LTGMGSESDMVVGLEMGADDYIAKPFNARVVVARVKAVLRRSEVLAIESSSVKACGLQFNGWRLNTDRCQLMNPQQQQID
LTQGEYGLLLSLMQNARKVLSREKLLELTHRESLDVFDRTIDVLIMRLRRKIEVNPHQPTLIRTIRGVGYVFAADIIHA

Specific function: Member of the two-component regulatory system ArcB/ArcA. Represses a wide variety of aerobic enzymes under anaerobic conditions [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=231, Percent_Identity=38.0952380952381, Blast_Score=157, Evalue=4e-40,
Organism=Escherichia coli, GI1790863, Length=235, Percent_Identity=34.8936170212766, Blast_Score=150, Evalue=6e-38,
Organism=Escherichia coli, GI1786599, Length=232, Percent_Identity=36.2068965517241, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1788394, Length=239, Percent_Identity=36.8200836820084, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI2367329, Length=231, Percent_Identity=36.7965367965368, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1787229, Length=237, Percent_Identity=34.5991561181435, Blast_Score=124, Evalue=8e-30,
Organism=Escherichia coli, GI1790860, Length=231, Percent_Identity=33.3333333333333, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1786784, Length=228, Percent_Identity=34.6491228070175, Blast_Score=117, Evalue=9e-28,
Organism=Escherichia coli, GI87082012, Length=230, Percent_Identity=33.0434782608696, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1787375, Length=229, Percent_Identity=31.8777292576419, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI145693140, Length=235, Percent_Identity=31.4893617021277, Blast_Score=95, Evalue=3e-21,
Organism=Escherichia coli, GI1786911, Length=228, Percent_Identity=28.9473684210526, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1789402, Length=230, Percent_Identity=30, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1790552, Length=233, Percent_Identity=31.7596566523605, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1790437, Length=136, Percent_Identity=31.6176470588235, Blast_Score=72, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26734; Mature: 26734

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPAILVVDDDTAICEVLRDVLNEHVFDVLLCHSGNEALQITATQPSIALILLDMMLPDI
CCCEEEEEECCHHHHHHHHHHHHHHHHHEEEEECCCCEEEEEECCCHHHHHHHHHHHCCC
NGLLVLQQVQKLRPSLPVVMLTGMGSESDMVVGLEMGADDYIAKPFNARVVVARVKAVLR
CHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEEEECCCCHHCCCCCCCHHHHHHHHHHH
RSEVLAIESSSVKACGLQFNGWRLNTDRCQLMNPQQQQIDLTQGEYGLLLSLMQNARKVL
HHHEEEEECCCCEEECEEECCEEECCCCCCCCCCHHHHEECCCCHHHHHHHHHHHHHHHH
SREKLLELTHRESLDVFDRTIDVLIMRLRRKIEVNPHQPTLIRTIRGVGYVFAADIIHA
HHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKPAILVVDDDTAICEVLRDVLNEHVFDVLLCHSGNEALQITATQPSIALILLDMMLPDI
CCCEEEEEECCHHHHHHHHHHHHHHHHHEEEEECCCCEEEEEECCCHHHHHHHHHHHCCC
NGLLVLQQVQKLRPSLPVVMLTGMGSESDMVVGLEMGADDYIAKPFNARVVVARVKAVLR
CHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEEEECCCCHHCCCCCCCHHHHHHHHHHH
RSEVLAIESSSVKACGLQFNGWRLNTDRCQLMNPQQQQIDLTQGEYGLLLSLMQNARKVL
HHHEEEEECCCCEEECEEECCEEECCCCCCCCCCHHHHEECCCCHHHHHHHHHHHHHHHH
SREKLLELTHRESLDVFDRTIDVLIMRLRRKIEVNPHQPTLIRTIRGVGYVFAADIIHA
HHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]