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The map label for this gene is hslO

Identifier: 51598051

GI number: 51598051

Start: 4463099

End: 4463980

Strand: Direct

Name: hslO

Synonym: YPTB3761

Alternate gene names: 51598051

Gene position: 4463099-4463980 (Clockwise)

Preceding gene: 51598050

Following gene: 51598052

Centisome position: 94.07

GC content: 49.09

Gene sequence:

>882_bases
ATGTCTAATCACGACCAATTACACCGCTATCTGTTTGCTAATCATGCTGTGCGCGGTGAACTGGTTTCAGTTAATGAAAC
CTACCAACAGGTATTAGCTAACCATGATTACCCACCAGCGGTACAGAAACTGTTGGGTGAAATGTTGGTCGCGACCAGCC
TGCTGACGGCCACCCTGAAATTTGATGGCGATATTACCGTGCAATTACAGGGCGGTGATGGCCCCTTAACATTGGCGGTC
ATTAACGGTAATAATCGGCAGGAAATGCGCGGTGTTGCTCGCGTTAAAGGCGAAATCAGCGATGACAGCACACTGCAAGA
GATGGTCGGTAACGGCTATCTGGTGATCACCATTACACCTGCACAAGGCGAACGCTATCAAGGGGTTGTGGCATTAGAAG
GTGAAACTATCGCGGCCTGCCTGGAAAATTACTTCATGCAGTCAGAGCAGTTACCGACCCGCCTGTTTATCCGCACCGGG
CATGTCGCCGATAAAGCGGCGGCAGGTGGCATGCTCCTGCAAGTACTGCCGGCGCAGGAACGTAATGAAGATGAATTTGA
CCATCTGGCACAGCTGACAGCGACCATTAAAGCTGAAGAGTTATTCACACTGCCAGCCAATGAAGTGCTGTATCGCCTGT
ATCATCAGGAGGAGGTGACGCTATATGAGCCACAAAATGTCAGCTTCCGCTGTACCTGCTCCCGCCAACGTTGTGCCGAT
GCCTTAGTGACGCTAGCTGACGATGACGTCACCGAAATGCTCGAGCAAGATGGCAATATTGATATGCATTGTGAATATTG
CGGTAACCATTATCTGTTTGATGCAGTTGATATTGCTACATTAAAAAATGGCAACAGCGCCTCTTCTGAACAAATTCATT
AA

Upstream 100 bases:

>100_bases
TTGAACGCTGCTTACAGCCAGGCGAGTCACGAACGTAGCCAACACCACCTGCAACTTGAAAGATGACGGATTTAAACGGC
GGCCAACATGAGAGAAAACT

Downstream 100 bases:

>100_bases
TCCTCGTAATGCTTAGCCGGGTACCTATTGGTGCCCGGCCATTTCCTCCGTTTCACACTTGCGATAATTCGTGTTCCATC
TCTCATAACCTAGCGAAAAA

Product: Hsp33-like chaperonin

Products: NA

Alternate protein names: Heat shock protein 33 homolog; HSP33

Number of amino acids: Translated: 293; Mature: 292

Protein sequence:

>293_residues
MSNHDQLHRYLFANHAVRGELVSVNETYQQVLANHDYPPAVQKLLGEMLVATSLLTATLKFDGDITVQLQGGDGPLTLAV
INGNNRQEMRGVARVKGEISDDSTLQEMVGNGYLVITITPAQGERYQGVVALEGETIAACLENYFMQSEQLPTRLFIRTG
HVADKAAAGGMLLQVLPAQERNEDEFDHLAQLTATIKAEELFTLPANEVLYRLYHQEEVTLYEPQNVSFRCTCSRQRCAD
ALVTLADDDVTEMLEQDGNIDMHCEYCGNHYLFDAVDIATLKNGNSASSEQIH

Sequences:

>Translated_293_residues
MSNHDQLHRYLFANHAVRGELVSVNETYQQVLANHDYPPAVQKLLGEMLVATSLLTATLKFDGDITVQLQGGDGPLTLAV
INGNNRQEMRGVARVKGEISDDSTLQEMVGNGYLVITITPAQGERYQGVVALEGETIAACLENYFMQSEQLPTRLFIRTG
HVADKAAAGGMLLQVLPAQERNEDEFDHLAQLTATIKAEELFTLPANEVLYRLYHQEEVTLYEPQNVSFRCTCSRQRCAD
ALVTLADDDVTEMLEQDGNIDMHCEYCGNHYLFDAVDIATLKNGNSASSEQIH
>Mature_292_residues
SNHDQLHRYLFANHAVRGELVSVNETYQQVLANHDYPPAVQKLLGEMLVATSLLTATLKFDGDITVQLQGGDGPLTLAVI
NGNNRQEMRGVARVKGEISDDSTLQEMVGNGYLVITITPAQGERYQGVVALEGETIAACLENYFMQSEQLPTRLFIRTGH
VADKAAAGGMLLQVLPAQERNEDEFDHLAQLTATIKAEELFTLPANEVLYRLYHQEEVTLYEPQNVSFRCTCSRQRCADA
LVTLADDDVTEMLEQDGNIDMHCEYCGNHYLFDAVDIATLKNGNSASSEQIH

Specific function: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress

COG id: COG1281

COG function: function code O; Disulfide bond chaperones of the HSP33 family

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HSP33 family

Homologues:

Organism=Escherichia coli, GI87082260, Length=293, Percent_Identity=71.6723549488055, Blast_Score=450, Evalue=1e-128,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HSLO_YERP3 (A7FNU7)

Other databases:

- EMBL:   CP000720
- RefSeq:   YP_001402925.1
- ProteinModelPortal:   A7FNU7
- SMR:   A7FNU7
- STRING:   A7FNU7
- GeneID:   5385763
- GenomeReviews:   CP000720_GR
- KEGG:   ypi:YpsIP31758_3977
- eggNOG:   COG1281
- HOGENOM:   HBG296531
- OMA:   AMTIDQG
- ProtClustDB:   PRK00114
- BioCyc:   YPSE349747:YPSIP31758_3977-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00117
- InterPro:   IPR000397
- InterPro:   IPR016154
- InterPro:   IPR016153
- InterPro:   IPR023212
- Gene3D:   G3DSA:1.10.287.480
- Gene3D:   G3DSA:3.90.1280.10
- Gene3D:   G3DSA:3.55.30.10
- PIRSF:   PIRSF005261

Pfam domain/function: PF01430 HSP33; SSF64397 Heat_shock_Hsp33_N

EC number: NA

Molecular weight: Translated: 32479; Mature: 32348

Theoretical pI: Translated: 4.37; Mature: 4.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNHDQLHRYLFANHAVRGELVSVNETYQQVLANHDYPPAVQKLLGEMLVATSLLTATLK
CCCHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHEEEE
FDGDITVQLQGGDGPLTLAVINGNNRQEMRGVARVKGEISDDSTLQEMVGNGYLVITITP
ECCEEEEEEECCCCCEEEEEEECCCHHHHHHHHHHCCCCCCCHHHHHHHCCCEEEEEEEC
AQGERYQGVVALEGETIAACLENYFMQSEQLPTRLFIRTGHVADKAAAGGMLLQVLPAQE
CCCCCCCCEEEECCCHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHCCCEEEEEECCCC
RNEDEFDHLAQLTATIKAEELFTLPANEVLYRLYHQEEVTLYEPQNVSFRCTCSRQRCAD
CCCHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHCCCCEEEECCCCCEEEEECCHHHHHH
ALVTLADDDVTEMLEQDGNIDMHCEYCGNHYLFDAVDIATLKNGNSASSEQIH
HHEECCCCHHHHHHHCCCCEEEEEEECCCEEEEEEEEEEEECCCCCCCCCCCC
>Mature Secondary Structure 
SNHDQLHRYLFANHAVRGELVSVNETYQQVLANHDYPPAVQKLLGEMLVATSLLTATLK
CCHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHEEEE
FDGDITVQLQGGDGPLTLAVINGNNRQEMRGVARVKGEISDDSTLQEMVGNGYLVITITP
ECCEEEEEEECCCCCEEEEEEECCCHHHHHHHHHHCCCCCCCHHHHHHHCCCEEEEEEEC
AQGERYQGVVALEGETIAACLENYFMQSEQLPTRLFIRTGHVADKAAAGGMLLQVLPAQE
CCCCCCCCEEEECCCHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHCCCEEEEEECCCC
RNEDEFDHLAQLTATIKAEELFTLPANEVLYRLYHQEEVTLYEPQNVSFRCTCSRQRCAD
CCCHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHCCCCEEEECCCCCEEEEECCHHHHHH
ALVTLADDDVTEMLEQDGNIDMHCEYCGNHYLFDAVDIATLKNGNSASSEQIH
HHEECCCCHHHHHHHCCCCEEEEEEECCCEEEEEEEEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA