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The map label for this gene is yheS

Identifier: 51598006

GI number: 51598006

Start: 4410481

End: 4412403

Strand: Direct

Name: yheS

Synonym: YPTB3716

Alternate gene names: 51598006

Gene position: 4410481-4412403 (Clockwise)

Preceding gene: 51598001

Following gene: 51598007

Centisome position: 92.96

GC content: 51.17

Gene sequence:

>1923_bases
ATGATTGTTTTTTCCTCGCTTCAAATTCGACGTGGTACTCGCGTCTTGCTGGACAACGCCACAGCTACGATTAACCCCGG
TCAGAAAGTCGGCCTGGTTGGCAAGAACGGTTGTGGTAAATCGACTCTGCTGGCGTTGCTCAAAGGCGAACTGAGCGCCG
ATGGGGGCAATGTCACATTTCCCAATAACTGGGCACTGGCCTGGGTTAATCAGGAAACCCCGGCACTGGATATCCCGGCG
ATAGAGTATGTTATCGACGGTGACCGCGAATATCGCCAGTTGGAGGCCGAACTTCAGGCTGCCAATGAAAAAAATGATGG
CCATGCCATCGCAACCGTGCACGGTAAGCTGGATGCCATCCATGCCTGGACTATCCAATCGCGTGCGGCCAGTTTGCTCC
ACGGGCTCGGGTTTTCTCAAGAAAAACTACAGCAACCGGTACGTTCATTTTCGGGTGGCTGGCGTATGCGTCTTAATCTG
GCGCAGGCGCTGGTTTGCCGCTCTGATTTACTGCTCTTGGATGAACCAACCAACCACTTGGATTTGGATGCCGTCATCTG
GCTGGAAAAATGGCTGAAAAGCTACACCGGTACCTTGGTATTAATTTCCCATGACCGCGATTTCCTTGATCCTATTATCG
ATAAGATTTTGCATATTGAACAGCAAACGCTGAATGAATATACCGGTAACTATTCATCGTTCGAACGCCAGCGCGCCACC
AAACTGTCGCAACAACAATCGATGTATCAGCATCAGCAAGAAAAAGTGGCGCATTTACAAAGTTATATTGATCGCTTCCG
GGCGCAAGCCACCAAAGCCAAGCAAGCCCAGAGCCGTATCAAGATGCTCGAGCGTATGGAGCTGATTGCCCCTGCACATG
TGGATAATCCGTTCCACTTCAGTTTTCGTACACCAGAAAGCCTGCCAGATCCCTTGCTGCGCATGGATAAAGTCAGTGCC
GGTTACGGGGAAAACACCGTCTTACAGTCCATTAAACTCAACCTGGTGCCCGGTTCACGCATCGGTCTCTTGGGGCGTAA
TGGTGCCGGTAAATCAACGCTGATTAAATTATTGGCCGGGACGTTAGAACCGCAAAGCGGTGAGATCGCCCTGTCCAAAG
GCATTAAACTCGGTTACTTCGCCCAGCATCAGTTGGAGTTCTTACGGGCTGATGAATCACCGTTGCAGCATATGAGCCGC
CTGGCCCCTAAAGAGTCAGAGCAGCAATTGCGCGATTATCTCGGTGGTTACGGCTTTCAGGGCGATCAGGTGACCGACCC
AACCGCCCGCTTTTCCGGTGGAGAGAAGGCGCGTTTAGTGCTGGCACTGATTATTTGGCAACGGCCGAATCTGTTACTGC
TGGATGAGCCCACCAACCATTTGGATTTGGACATGCGACAAGCCCTGACCGAGGCTCTGATTGATTTTGAAGGCGCATTG
GTGGTGGTTTCCCATGACCGTCATTTACTGCGCTCTACCACCGATGACCTCTATCTGGTGCACGACGGTAAAGTGGAACA
GTTCGATGGCGATCTGGAAGATTATCAGCAGTGGCTGGTGGATTCACAGCGCCAGCAAAGCCAACAGGATAATCCGGCGA
AGGAGCTATCGGGCAACAGCGCACAACAGCGTAAAGACCAAAAACGTCGCGATGCTGAATTCCGCACTCAAACGCAGCCA
CTGCGTAAGCAGATTATGACGCTGGAAAAACAGATGGATAAACTCAGCACTGAGCTGGCCGCTATCGAAGCACAGTTGGC
GGATTCAGCACTGTATGATATTGCGCGCAAAGCGGACTTGACCCAATGCCTACTGCAACAAACGCAAGTGAAATCCAAGC
TGGAAGAGACGGAAATGCAGTGGTTAGATGTGCAAGAACAGCTTGAAATACTGACTAAAGAGTTTAGCGATGCCGATATA
TAA

Upstream 100 bases:

>100_bases
TACTCAAGTCAGTCATTAGGATGAGTGAACGTGGCTAACCCCTGTAACTTCAAGTGCAAAGGGGATGATAATTTAACATA
TCCTAAACATACGGCACTCT

Downstream 100 bases:

>100_bases
TATCGGAAATATAGATATAACATCGCGAATGTAAATATGGCATCGTGAATATAGTCGTGCGAATTGAGTTAGAGTCGCAC
GACTAGAGCGGCGTGATTTT

Product: ABC transporter ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 640; Mature: 640

Protein sequence:

>640_residues
MIVFSSLQIRRGTRVLLDNATATINPGQKVGLVGKNGCGKSTLLALLKGELSADGGNVTFPNNWALAWVNQETPALDIPA
IEYVIDGDREYRQLEAELQAANEKNDGHAIATVHGKLDAIHAWTIQSRAASLLHGLGFSQEKLQQPVRSFSGGWRMRLNL
AQALVCRSDLLLLDEPTNHLDLDAVIWLEKWLKSYTGTLVLISHDRDFLDPIIDKILHIEQQTLNEYTGNYSSFERQRAT
KLSQQQSMYQHQQEKVAHLQSYIDRFRAQATKAKQAQSRIKMLERMELIAPAHVDNPFHFSFRTPESLPDPLLRMDKVSA
GYGENTVLQSIKLNLVPGSRIGLLGRNGAGKSTLIKLLAGTLEPQSGEIALSKGIKLGYFAQHQLEFLRADESPLQHMSR
LAPKESEQQLRDYLGGYGFQGDQVTDPTARFSGGEKARLVLALIIWQRPNLLLLDEPTNHLDLDMRQALTEALIDFEGAL
VVVSHDRHLLRSTTDDLYLVHDGKVEQFDGDLEDYQQWLVDSQRQQSQQDNPAKELSGNSAQQRKDQKRRDAEFRTQTQP
LRKQIMTLEKQMDKLSTELAAIEAQLADSALYDIARKADLTQCLLQQTQVKSKLEETEMQWLDVQEQLEILTKEFSDADI

Sequences:

>Translated_640_residues
MIVFSSLQIRRGTRVLLDNATATINPGQKVGLVGKNGCGKSTLLALLKGELSADGGNVTFPNNWALAWVNQETPALDIPA
IEYVIDGDREYRQLEAELQAANEKNDGHAIATVHGKLDAIHAWTIQSRAASLLHGLGFSQEKLQQPVRSFSGGWRMRLNL
AQALVCRSDLLLLDEPTNHLDLDAVIWLEKWLKSYTGTLVLISHDRDFLDPIIDKILHIEQQTLNEYTGNYSSFERQRAT
KLSQQQSMYQHQQEKVAHLQSYIDRFRAQATKAKQAQSRIKMLERMELIAPAHVDNPFHFSFRTPESLPDPLLRMDKVSA
GYGENTVLQSIKLNLVPGSRIGLLGRNGAGKSTLIKLLAGTLEPQSGEIALSKGIKLGYFAQHQLEFLRADESPLQHMSR
LAPKESEQQLRDYLGGYGFQGDQVTDPTARFSGGEKARLVLALIIWQRPNLLLLDEPTNHLDLDMRQALTEALIDFEGAL
VVVSHDRHLLRSTTDDLYLVHDGKVEQFDGDLEDYQQWLVDSQRQQSQQDNPAKELSGNSAQQRKDQKRRDAEFRTQTQP
LRKQIMTLEKQMDKLSTELAAIEAQLADSALYDIARKADLTQCLLQQTQVKSKLEETEMQWLDVQEQLEILTKEFSDADI
>Mature_640_residues
MIVFSSLQIRRGTRVLLDNATATINPGQKVGLVGKNGCGKSTLLALLKGELSADGGNVTFPNNWALAWVNQETPALDIPA
IEYVIDGDREYRQLEAELQAANEKNDGHAIATVHGKLDAIHAWTIQSRAASLLHGLGFSQEKLQQPVRSFSGGWRMRLNL
AQALVCRSDLLLLDEPTNHLDLDAVIWLEKWLKSYTGTLVLISHDRDFLDPIIDKILHIEQQTLNEYTGNYSSFERQRAT
KLSQQQSMYQHQQEKVAHLQSYIDRFRAQATKAKQAQSRIKMLERMELIAPAHVDNPFHFSFRTPESLPDPLLRMDKVSA
GYGENTVLQSIKLNLVPGSRIGLLGRNGAGKSTLIKLLAGTLEPQSGEIALSKGIKLGYFAQHQLEFLRADESPLQHMSR
LAPKESEQQLRDYLGGYGFQGDQVTDPTARFSGGEKARLVLALIIWQRPNLLLLDEPTNHLDLDMRQALTEALIDFEGAL
VVVSHDRHLLRSTTDDLYLVHDGKVEQFDGDLEDYQQWLVDSQRQQSQQDNPAKELSGNSAQQRKDQKRRDAEFRTQTQP
LRKQIMTLEKQMDKLSTELAAIEAQLADSALYDIARKADLTQCLLQQTQVKSKLEETEMQWLDVQEQLEILTKEFSDADI

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=537, Percent_Identity=37.6163873370577, Blast_Score=374, Evalue=1e-103,
Organism=Homo sapiens, GI10947137, Length=527, Percent_Identity=36.2428842504744, Blast_Score=325, Evalue=8e-89,
Organism=Homo sapiens, GI27881506, Length=526, Percent_Identity=35.7414448669202, Blast_Score=324, Evalue=1e-88,
Organism=Homo sapiens, GI69354671, Length=551, Percent_Identity=34.8457350272232, Blast_Score=276, Evalue=3e-74,
Organism=Homo sapiens, GI10947135, Length=551, Percent_Identity=34.8457350272232, Blast_Score=276, Evalue=3e-74,
Organism=Escherichia coli, GI1789751, Length=629, Percent_Identity=81.5580286168522, Blast_Score=1067, Evalue=0.0,
Organism=Escherichia coli, GI1787041, Length=527, Percent_Identity=33.7760910815939, Blast_Score=308, Evalue=7e-85,
Organism=Escherichia coli, GI2367384, Length=528, Percent_Identity=31.0606060606061, Blast_Score=229, Evalue=4e-61,
Organism=Escherichia coli, GI1787182, Length=594, Percent_Identity=27.6094276094276, Blast_Score=228, Evalue=7e-61,
Organism=Escherichia coli, GI1788165, Length=191, Percent_Identity=34.0314136125654, Blast_Score=100, Evalue=5e-22,
Organism=Escherichia coli, GI87081782, Length=553, Percent_Identity=25.1356238698011, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI48994997, Length=248, Percent_Identity=27.0161290322581, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1787164, Length=215, Percent_Identity=29.7674418604651, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI87081791, Length=225, Percent_Identity=26.6666666666667, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87081709, Length=225, Percent_Identity=24, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1789672, Length=218, Percent_Identity=26.1467889908257, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1787547, Length=200, Percent_Identity=25.5, Blast_Score=73, Evalue=6e-14,
Organism=Escherichia coli, GI1787758, Length=208, Percent_Identity=26.4423076923077, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1789891, Length=207, Percent_Identity=27.536231884058, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1786803, Length=218, Percent_Identity=27.0642201834862, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI48994883, Length=219, Percent_Identity=27.8538812785388, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1787500, Length=305, Percent_Identity=22.9508196721311, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1788506, Length=257, Percent_Identity=24.9027237354086, Blast_Score=64, Evalue=4e-11,
Organism=Escherichia coli, GI1786703, Length=213, Percent_Identity=29.1079812206573, Blast_Score=62, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17553372, Length=530, Percent_Identity=38.6792452830189, Blast_Score=358, Evalue=4e-99,
Organism=Caenorhabditis elegans, GI17555318, Length=540, Percent_Identity=35, Blast_Score=328, Evalue=4e-90,
Organism=Caenorhabditis elegans, GI17559834, Length=548, Percent_Identity=33.5766423357664, Blast_Score=311, Evalue=5e-85,
Organism=Caenorhabditis elegans, GI115533592, Length=267, Percent_Identity=25.0936329588015, Blast_Score=65, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6321121, Length=546, Percent_Identity=35.8974358974359, Blast_Score=348, Evalue=1e-96,
Organism=Saccharomyces cerevisiae, GI6320874, Length=529, Percent_Identity=35.1606805293006, Blast_Score=328, Evalue=1e-90,
Organism=Saccharomyces cerevisiae, GI6325030, Length=391, Percent_Identity=30.9462915601023, Blast_Score=161, Evalue=3e-40,
Organism=Saccharomyces cerevisiae, GI6324314, Length=400, Percent_Identity=29, Blast_Score=147, Evalue=7e-36,
Organism=Saccharomyces cerevisiae, GI6323278, Length=392, Percent_Identity=28.0612244897959, Blast_Score=141, Evalue=3e-34,
Organism=Drosophila melanogaster, GI24666836, Length=519, Percent_Identity=38.150289017341, Blast_Score=374, Evalue=1e-103,
Organism=Drosophila melanogaster, GI24642252, Length=528, Percent_Identity=38.4469696969697, Blast_Score=365, Evalue=1e-101,
Organism=Drosophila melanogaster, GI18859989, Length=528, Percent_Identity=38.4469696969697, Blast_Score=365, Evalue=1e-101,
Organism=Drosophila melanogaster, GI24641342, Length=533, Percent_Identity=35.0844277673546, Blast_Score=308, Evalue=6e-84,
Organism=Drosophila melanogaster, GI116007184, Length=200, Percent_Identity=28, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI221500365, Length=200, Percent_Identity=28, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI28574259, Length=246, Percent_Identity=26.8292682926829, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 72171; Mature: 72171

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVFSSLQIRRGTRVLLDNATATINPGQKVGLVGKNGCGKSTLLALLKGELSADGGNVTF
CEEECCEEECCCCEEEEECCEEEECCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCEEC
PNNWALAWVNQETPALDIPAIEYVIDGDREYRQLEAELQAANEKNDGHAIATVHGKLDAI
CCCEEEEEECCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCCEEEEEECCCCEE
HAWTIQSRAASLLHGLGFSQEKLQQPVRSFSGGWRMRLNLAQALVCRSDLLLLDEPTNHL
EEHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEHHHHHHHHHHCCEEEEECCCCCC
DLDAVIWLEKWLKSYTGTLVLISHDRDFLDPIIDKILHIEQQTLNEYTGNYSSFERQRAT
CHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
KLSQQQSMYQHQQEKVAHLQSYIDRFRAQATKAKQAQSRIKMLERMELIAPAHVDNPFHF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEE
SFRTPESLPDPLLRMDKVSAGYGENTVLQSIKLNLVPGSRIGLLGRNGAGKSTLIKLLAG
EECCCCCCCCHHHHHHHHCCCCCCHHHHHHEEEEECCCCCEEEEECCCCCHHHHHHHHHH
TLEPQSGEIALSKGIKLGYFAQHQLEFLRADESPLQHMSRLAPKESEQQLRDYLGGYGFQ
CCCCCCCCEEEECCCEEEHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHCCCCCC
GDQVTDPTARFSGGEKARLVLALIIWQRPNLLLLDEPTNHLDLDMRQALTEALIDFEGAL
CCCCCCCHHHCCCCCHHHHHEEEHEECCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCEE
VVVSHDRHLLRSTTDDLYLVHDGKVEQFDGDLEDYQQWLVDSQRQQSQQDNPAKELSGNS
EEEECCCHHHHCCCCCEEEEECCCHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHCCCC
AQQRKDQKRRDAEFRTQTQPLRKQIMTLEKQMDKLSTELAAIEAQLADSALYDIARKADL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TQCLLQQTQVKSKLEETEMQWLDVQEQLEILTKEFSDADI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MIVFSSLQIRRGTRVLLDNATATINPGQKVGLVGKNGCGKSTLLALLKGELSADGGNVTF
CEEECCEEECCCCEEEEECCEEEECCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCEEC
PNNWALAWVNQETPALDIPAIEYVIDGDREYRQLEAELQAANEKNDGHAIATVHGKLDAI
CCCEEEEEECCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCCEEEEEECCCCEE
HAWTIQSRAASLLHGLGFSQEKLQQPVRSFSGGWRMRLNLAQALVCRSDLLLLDEPTNHL
EEHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEHHHHHHHHHHCCEEEEECCCCCC
DLDAVIWLEKWLKSYTGTLVLISHDRDFLDPIIDKILHIEQQTLNEYTGNYSSFERQRAT
CHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
KLSQQQSMYQHQQEKVAHLQSYIDRFRAQATKAKQAQSRIKMLERMELIAPAHVDNPFHF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEE
SFRTPESLPDPLLRMDKVSAGYGENTVLQSIKLNLVPGSRIGLLGRNGAGKSTLIKLLAG
EECCCCCCCCHHHHHHHHCCCCCCHHHHHHEEEEECCCCCEEEEECCCCCHHHHHHHHHH
TLEPQSGEIALSKGIKLGYFAQHQLEFLRADESPLQHMSRLAPKESEQQLRDYLGGYGFQ
CCCCCCCCEEEECCCEEEHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHCCCCCC
GDQVTDPTARFSGGEKARLVLALIIWQRPNLLLLDEPTNHLDLDMRQALTEALIDFEGAL
CCCCCCCHHHCCCCCHHHHHEEEHEECCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCEE
VVVSHDRHLLRSTTDDLYLVHDGKVEQFDGDLEDYQQWLVDSQRQQSQQDNPAKELSGNS
EEEECCCHHHHCCCCCEEEEECCCHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHCCCC
AQQRKDQKRRDAEFRTQTQPLRKQIMTLEKQMDKLSTELAAIEAQLADSALYDIARKADL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TQCLLQQTQVKSKLEETEMQWLDVQEQLEILTKEFSDADI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]