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The map label for this gene is malF

Identifier: 51597937

GI number: 51597937

Start: 4341831

End: 4343408

Strand: Direct

Name: malF

Synonym: YPTB3646

Alternate gene names: 51597937

Gene position: 4341831-4343408 (Clockwise)

Preceding gene: 51597936

Following gene: 51597938

Centisome position: 91.51

GC content: 48.48

Gene sequence:

>1578_bases
ATGCAGTTATCCCACACCGAGCTTCAAAGCCGAAAAAAGAAAATCGCCTGGTGGCAGAGTGATGCGCTTAAATGGTTGGT
TATCAGCCTGTTAAGCCTCTTCACCTGTTATTTGATCGTGTTGATGTATGCTCAAGGTGAATATCTTTTTGCCATCGTGA
CGCTGATTTTGGTGAGTTTAGGGCTGTATGTGTTTGCCAACCGCCGCGCTTATGCCTGGCGCTATGTTTACCCCGGCGTG
GCCGGTATGGGGCTGTTTGTTCTCTTCCCCTTAATTTGTACTATCGCCATCGCCTTTACTAACTACAGCAGTACCAACCA
ATTAACCTTCGAACGTGCTCAATCCGTCTTGCTGGATCGGCAGTTCCAGACCGGTAAAACATTTACCTTTGGTCTCTATC
CCAGCGATAACCAATGGCGTTTACAGCTTACCAACCCAGACGACGGTAGCCTGTTCATCTCTGAACCCTTCAGTTTTGAG
GCCACGGGTGAGCAAAAAGTGATGGTCGCCCCAACCAATACGGCACAAACGAGTGAACCGGCATCACTGCGGATTATTAC
CCAGAGTCGTCAGGCGCTAAGTGGCTTAGTGGCTATCCTGCCTGATGGTGCTGAACTGCGTATGAGTTCATTACGTCAAT
TTTCCGGCACCAAGCCGCTCTATACTCTGGGTGCCGATGGTAAAGAACTGATTAATCAGCAAACCGGCGTGAAATATTGG
CCGAATCCTAATACCGGGTTCTATCAAGCGGTCAACGCTGATGGACAGTGGGAAAATGAAAAGCTTAGCCCCGGCTTTAC
CGTATCTATCGGCTGGAAAAACTTCCTGCGGGTACTGCACGACGAAGGGATTCAAAAGCCGTTCATCTCGATCTTTATCT
GGACTATCCTCTTCTCGGTAATGAGCGTGACCTTTACGGTAGCTGTCGGCATGGTGCTGGCATGTGTGGTGCAATGGGAT
TCGCTGAAAGGTAAAGCGATCTATCGGGTGATGCTGATCCTGCCCTATGCGGTACCGTCGTTTATCTCTATTCTGATTTT
CAAAGGGTTATTTAACCAAAGTTTCGGTGAAATCAACCTGATGCTCAGCCATTTATTTGGCATCAAACCCGCCTGGTTCA
GTGATCCTATCACCGCCAAAAGCATGATTTTAATCGTGAATACCTGGCTCGGTTATCCCTACATGATGATTTTGTGCATG
GGGCTGTTGAAAGCGATCCCTGACGACTTGTATGAGGCATCGGCAATGGATGGCGCAGGGCCATTCCAGAACTTTTTCCG
CATCACGTTTCCGTTACTGATTAAGCCACTGACACCGCTGATGATTGCCAGTTTTGCCTTTAACTTTAATAACTTCGTGC
TAATCCAGCTATTGACCAACGGGGGACCCGATATGATTGGTACCAGCACCCCAGCGGGGTATACCGATTTGCTGGTTAAC
TATACCTATCGTGTCGCCTTTGAAGGCGAAGGCGGGCAGGACTTCGGTTTGGCAGCCGCTATCGCAACCCTGATTTTCAT
TTTGGTAGGCGCACTCGCGATACTGAATTTGAAAGCCAGCAAAATGAATTTTGACTAA

Upstream 100 bases:

>100_bases
TAAACACGACCCAACGTTAAACACGGCTCAACTTTAAGCACAACTTATTAAGTTCAAGCACAACTTAACTTCAAGCACAA
AAAGTATGAAAGGGAACATT

Downstream 100 bases:

>100_bases
GGAGGAGATGCAGATGGCTATGGTTCAACCTAAATCCCAGCGTTTGCGTCTATTGGGCACGCATTTTCTGATGTTGTGCT
TTATCGCGCTGATCATGTTC

Product: maltose transporter membrane protein

Products: ADP; phosphate; maltose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 525; Mature: 525

Protein sequence:

>525_residues
MQLSHTELQSRKKKIAWWQSDALKWLVISLLSLFTCYLIVLMYAQGEYLFAIVTLILVSLGLYVFANRRAYAWRYVYPGV
AGMGLFVLFPLICTIAIAFTNYSSTNQLTFERAQSVLLDRQFQTGKTFTFGLYPSDNQWRLQLTNPDDGSLFISEPFSFE
ATGEQKVMVAPTNTAQTSEPASLRIITQSRQALSGLVAILPDGAELRMSSLRQFSGTKPLYTLGADGKELINQQTGVKYW
PNPNTGFYQAVNADGQWENEKLSPGFTVSIGWKNFLRVLHDEGIQKPFISIFIWTILFSVMSVTFTVAVGMVLACVVQWD
SLKGKAIYRVMLILPYAVPSFISILIFKGLFNQSFGEINLMLSHLFGIKPAWFSDPITAKSMILIVNTWLGYPYMMILCM
GLLKAIPDDLYEASAMDGAGPFQNFFRITFPLLIKPLTPLMIASFAFNFNNFVLIQLLTNGGPDMIGTSTPAGYTDLLVN
YTYRVAFEGEGGQDFGLAAAIATLIFILVGALAILNLKASKMNFD

Sequences:

>Translated_525_residues
MQLSHTELQSRKKKIAWWQSDALKWLVISLLSLFTCYLIVLMYAQGEYLFAIVTLILVSLGLYVFANRRAYAWRYVYPGV
AGMGLFVLFPLICTIAIAFTNYSSTNQLTFERAQSVLLDRQFQTGKTFTFGLYPSDNQWRLQLTNPDDGSLFISEPFSFE
ATGEQKVMVAPTNTAQTSEPASLRIITQSRQALSGLVAILPDGAELRMSSLRQFSGTKPLYTLGADGKELINQQTGVKYW
PNPNTGFYQAVNADGQWENEKLSPGFTVSIGWKNFLRVLHDEGIQKPFISIFIWTILFSVMSVTFTVAVGMVLACVVQWD
SLKGKAIYRVMLILPYAVPSFISILIFKGLFNQSFGEINLMLSHLFGIKPAWFSDPITAKSMILIVNTWLGYPYMMILCM
GLLKAIPDDLYEASAMDGAGPFQNFFRITFPLLIKPLTPLMIASFAFNFNNFVLIQLLTNGGPDMIGTSTPAGYTDLLVN
YTYRVAFEGEGGQDFGLAAAIATLIFILVGALAILNLKASKMNFD
>Mature_525_residues
MQLSHTELQSRKKKIAWWQSDALKWLVISLLSLFTCYLIVLMYAQGEYLFAIVTLILVSLGLYVFANRRAYAWRYVYPGV
AGMGLFVLFPLICTIAIAFTNYSSTNQLTFERAQSVLLDRQFQTGKTFTFGLYPSDNQWRLQLTNPDDGSLFISEPFSFE
ATGEQKVMVAPTNTAQTSEPASLRIITQSRQALSGLVAILPDGAELRMSSLRQFSGTKPLYTLGADGKELINQQTGVKYW
PNPNTGFYQAVNADGQWENEKLSPGFTVSIGWKNFLRVLHDEGIQKPFISIFIWTILFSVMSVTFTVAVGMVLACVVQWD
SLKGKAIYRVMLILPYAVPSFISILIFKGLFNQSFGEINLMLSHLFGIKPAWFSDPITAKSMILIVNTWLGYPYMMILCM
GLLKAIPDDLYEASAMDGAGPFQNFFRITFPLLIKPLTPLMIASFAFNFNNFVLIQLLTNGGPDMIGTSTPAGYTDLLVN
YTYRVAFEGEGGQDFGLAAAIATLIFILVGALAILNLKASKMNFD

Specific function: Part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1175

COG function: function code G; ABC-type sugar transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1790465, Length=513, Percent_Identity=75.4385964912281, Blast_Score=790, Evalue=0.0,
Organism=Escherichia coli, GI1787570, Length=258, Percent_Identity=27.5193798449612, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1789861, Length=254, Percent_Identity=28.740157480315, Blast_Score=83, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 58546; Mature: 58546

Theoretical pI: Translated: 8.24; Mature: 8.24

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLSHTELQSRKKKIAWWQSDALKWLVISLLSLFTCYLIVLMYAQGEYLFAIVTLILVSL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
GLYVFANRRAYAWRYVYPGVAGMGLFVLFPLICTIAIAFTNYSSTNQLTFERAQSVLLDR
HHHHEECCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHC
QFQTGKTFTFGLYPSDNQWRLQLTNPDDGSLFISEPFSFEATGEQKVMVAPTNTAQTSEP
CCCCCCEEEEEECCCCCCEEEEECCCCCCCEEEECCCCCCCCCCCEEEEECCCCCCCCCC
ASLRIITQSRQALSGLVAILPDGAELRMSSLRQFSGTKPLYTLGADGKELINQQTGVKYW
CEEEEEEHHHHHHHCEEEECCCCHHHHHHHHHHHCCCCCEEEECCCHHHHHHHCCCCEEC
PNPNTGFYQAVNADGQWENEKLSPGFTVSIGWKNFLRVLHDEGIQKPFISIFIWTILFSV
CCCCCCEEEEECCCCCCCCCCCCCCEEEEECHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
MSVTFTVAVGMVLACVVQWDSLKGKAIYRVMLILPYAVPSFISILIFKGLFNQSFGEINL
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
MLSHLFGIKPAWFSDPITAKSMILIVNTWLGYPYMMILCMGLLKAIPDDLYEASAMDGAG
HHHHHHCCCCCCCCCCCCCCCEEEEEEHHHCHHHHHHHHHHHHHHCCHHHHHHHCCCCCC
PFQNFFRITFPLLIKPLTPLMIASFAFNFNNFVLIQLLTNGGPDMIGTSTPAGYTDLLVN
HHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCCHHHHHEE
YTYRVAFEGEGGQDFGLAAAIATLIFILVGALAILNLKASKMNFD
EEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCC
>Mature Secondary Structure
MQLSHTELQSRKKKIAWWQSDALKWLVISLLSLFTCYLIVLMYAQGEYLFAIVTLILVSL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
GLYVFANRRAYAWRYVYPGVAGMGLFVLFPLICTIAIAFTNYSSTNQLTFERAQSVLLDR
HHHHEECCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHC
QFQTGKTFTFGLYPSDNQWRLQLTNPDDGSLFISEPFSFEATGEQKVMVAPTNTAQTSEP
CCCCCCEEEEEECCCCCCEEEEECCCCCCCEEEECCCCCCCCCCCEEEEECCCCCCCCCC
ASLRIITQSRQALSGLVAILPDGAELRMSSLRQFSGTKPLYTLGADGKELINQQTGVKYW
CEEEEEEHHHHHHHCEEEECCCCHHHHHHHHHHHCCCCCEEEECCCHHHHHHHCCCCEEC
PNPNTGFYQAVNADGQWENEKLSPGFTVSIGWKNFLRVLHDEGIQKPFISIFIWTILFSV
CCCCCCEEEEECCCCCCCCCCCCCCEEEEECHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
MSVTFTVAVGMVLACVVQWDSLKGKAIYRVMLILPYAVPSFISILIFKGLFNQSFGEINL
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
MLSHLFGIKPAWFSDPITAKSMILIVNTWLGYPYMMILCMGLLKAIPDDLYEASAMDGAG
HHHHHHCCCCCCCCCCCCCCCEEEEEEHHHCHHHHHHHHHHHHHHCCHHHHHHHCCCCCC
PFQNFFRITFPLLIKPLTPLMIASFAFNFNNFVLIQLLTNGGPDMIGTSTPAGYTDLLVN
HHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCCHHHHHEE
YTYRVAFEGEGGQDFGLAAAIATLIFILVGALAILNLKASKMNFD
EEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; maltose [Periplasm]; H2O [C]

Specific reaction: ATP + maltose [Periplasm] + H2O = ADP + phosphate + maltose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]