Click here to switch to the map view.

The map label for this gene is rbsK [H]

Identifier: 51597899

GI number: 51597899

Start: 4292045

End: 4292974

Strand: Direct

Name: rbsK [H]

Synonym: YPTB3608

Alternate gene names: 51597899

Gene position: 4292045-4292974 (Clockwise)

Preceding gene: 51597898

Following gene: 51597900

Centisome position: 90.46

GC content: 53.76

Gene sequence:

>930_bases
ATGAGTGTATTTATTCTCGGCAGCTATGCGAAAGCGCTGGTGATGACCACCGACCGTATTCCTCTGGCTGGGGAAACGCT
GATTGGCTATGACTTTCGCCAGACGTGGGGCGGTAAAGGCTCGGATATGGCGGTTCAGGCAGTGCGTCTGGGGGCAGAGG
TCGCCTATGCGGGTGTCGTCGGTGATGACACCTTTGGCCATGAATTTGTCGGCTTGATGCAGGAAGAAGGCGTCAATATC
GACGCATTAACCATCAGCGGAGAATTACCAACGGGGGCGGGACTTATCGTTAAAGATAAAGAAGCCCGTAACGTGATTGT
CGTGGATATGGGGGCCAATAAACTGTTTACCCCAGCGTTGGTGGACAGCGCCTTATCCCAGCTCAAACAAAGCAATGTGG
TGCTCGCACAGCTTGAAATTCCGCTGGAAACGGCACTTTACGGACTCCAACGGGCAAAAGAATTCGGCAAAATAACCATC
CTGAACCCGGCTCCGGCAAGGGATCTGCGCGGTCTCGATCTCAGCGCGATTGATTATTTGACCCCTAATGAAACGGAAGC
CCGCGTGGCTCTGGGTCTGCCTCCGGATGACCCACGCAGTAACCGAGAGATTGCCAACCTCTTACTGGAAACCGGTTGCC
AATATGTCGTGATGACGCTGGGTGAATCAGGTTCTGCGGTGTTTGGTCGCAACGACACACAAGAAATCCCCCCCTGCATC
ATTGATGTCGTCGACAGTAACGGTGCAGGTGACAGCTTTAACGCGGCACTGGCCGTCGCGCTGGATGAAGGGCTGCCGAT
TAGCGAAGCTGTGCTGTTTGCTAACGCCACGGCGGCGTTGTGCTGTATGGATTGGGAAACGGTTCCGTCCTATCGCTACC
GCGAAGATGTCGATGCTTTTATGCGATCTATAACCGTGAAAGAGGAATAA

Upstream 100 bases:

>100_bases
AACAAATAGACTATGCAAATGAATAACAAACAGACTTCGCAAATTAATAACAAACAAACTATGCAATGAATAACAAACAG
CACAGTTAAAGGAGTATGTG

Downstream 100 bases:

>100_bases
CAATAATGAGACCCGATAGAATCTTACACCCTGAACTTGCCGCCGCTTTAGCCACCTTAGGCCATACCGACATTATATTG
GTCACGGATGCAGGCTTCCC

Product: carbohydrate kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MSVFILGSYAKALVMTTDRIPLAGETLIGYDFRQTWGGKGSDMAVQAVRLGAEVAYAGVVGDDTFGHEFVGLMQEEGVNI
DALTISGELPTGAGLIVKDKEARNVIVVDMGANKLFTPALVDSALSQLKQSNVVLAQLEIPLETALYGLQRAKEFGKITI
LNPAPARDLRGLDLSAIDYLTPNETEARVALGLPPDDPRSNREIANLLLETGCQYVVMTLGESGSAVFGRNDTQEIPPCI
IDVVDSNGAGDSFNAALAVALDEGLPISEAVLFANATAALCCMDWETVPSYRYREDVDAFMRSITVKEE

Sequences:

>Translated_309_residues
MSVFILGSYAKALVMTTDRIPLAGETLIGYDFRQTWGGKGSDMAVQAVRLGAEVAYAGVVGDDTFGHEFVGLMQEEGVNI
DALTISGELPTGAGLIVKDKEARNVIVVDMGANKLFTPALVDSALSQLKQSNVVLAQLEIPLETALYGLQRAKEFGKITI
LNPAPARDLRGLDLSAIDYLTPNETEARVALGLPPDDPRSNREIANLLLETGCQYVVMTLGESGSAVFGRNDTQEIPPCI
IDVVDSNGAGDSFNAALAVALDEGLPISEAVLFANATAALCCMDWETVPSYRYREDVDAFMRSITVKEE
>Mature_308_residues
SVFILGSYAKALVMTTDRIPLAGETLIGYDFRQTWGGKGSDMAVQAVRLGAEVAYAGVVGDDTFGHEFVGLMQEEGVNID
ALTISGELPTGAGLIVKDKEARNVIVVDMGANKLFTPALVDSALSQLKQSNVVLAQLEIPLETALYGLQRAKEFGKITIL
NPAPARDLRGLDLSAIDYLTPNETEARVALGLPPDDPRSNREIANLLLETGCQYVVMTLGESGSAVFGRNDTQEIPPCII
DVVDSNGAGDSFNAALAVALDEGLPISEAVLFANATAALCCMDWETVPSYRYREDVDAFMRSITVKEE

Specific function: Ribose metabolism; first step. [C]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=296, Percent_Identity=34.1216216216216, Blast_Score=153, Evalue=2e-37,
Organism=Escherichia coli, GI1790193, Length=300, Percent_Identity=35, Blast_Score=167, Evalue=1e-42,
Organism=Escherichia coli, GI87081971, Length=282, Percent_Identity=27.3049645390071, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI87082343, Length=270, Percent_Identity=27.4074074074074, Blast_Score=71, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17532905, Length=292, Percent_Identity=33.2191780821918, Blast_Score=148, Evalue=4e-36,
Organism=Saccharomyces cerevisiae, GI6319884, Length=328, Percent_Identity=27.7439024390244, Blast_Score=90, Evalue=4e-19,
Organism=Drosophila melanogaster, GI20128807, Length=267, Percent_Identity=34.0823970037453, Blast_Score=125, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24583886, Length=307, Percent_Identity=24.7557003257329, Blast_Score=82, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 33051; Mature: 32920

Theoretical pI: Translated: 4.09; Mature: 4.09

Prosite motif: PS00059 ADH_ZINC ; PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVFILGSYAKALVMTTDRIPLAGETLIGYDFRQTWGGKGSDMAVQAVRLGAEVAYAGVV
CEEEEEECCCEEEEEEECCCCCCCCEEECCCHHHHCCCCCCCHHHHHHHHCCCEEEEEEE
GDDTFGHEFVGLMQEEGVNIDALTISGELPTGAGLIVKDKEARNVIVVDMGANKLFTPAL
CCCCCCHHHHHHHHHCCCCEEEEEEECCCCCCCEEEEECCCCCEEEEEEECCCCCCCHHH
VDSALSQLKQSNVVLAQLEIPLETALYGLQRAKEFGKITILNPAPARDLRGLDLSAIDYL
HHHHHHHHHHCCEEEEEEECCHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCEEECC
TPNETEARVALGLPPDDPRSNREIANLLLETGCQYVVMTLGESGSAVFGRNDTQEIPPCI
CCCCCCCEEEECCCCCCCCCHHHHHHHHHHCCCEEEEEEECCCCCEEECCCCCCCCCCEE
IDVVDSNGAGDSFNAALAVALDEGLPISEAVLFANATAALCCMDWETVPSYRYREDVDAF
EEEECCCCCCCCCCEEEEEEECCCCCHHHHEEEECCCEEEEEECCCCCCCCHHHHHHHHH
MRSITVKEE
HHHCCCCCC
>Mature Secondary Structure 
SVFILGSYAKALVMTTDRIPLAGETLIGYDFRQTWGGKGSDMAVQAVRLGAEVAYAGVV
EEEEEECCCEEEEEEECCCCCCCCEEECCCHHHHCCCCCCCHHHHHHHHCCCEEEEEEE
GDDTFGHEFVGLMQEEGVNIDALTISGELPTGAGLIVKDKEARNVIVVDMGANKLFTPAL
CCCCCCHHHHHHHHHCCCCEEEEEEECCCCCCCEEEEECCCCCEEEEEEECCCCCCCHHH
VDSALSQLKQSNVVLAQLEIPLETALYGLQRAKEFGKITILNPAPARDLRGLDLSAIDYL
HHHHHHHHHHCCEEEEEEECCHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCEEECC
TPNETEARVALGLPPDDPRSNREIANLLLETGCQYVVMTLGESGSAVFGRNDTQEIPPCI
CCCCCCCEEEECCCCCCCCCHHHHHHHHHHCCCEEEEEEECCCCCEEECCCCCCCCCCEE
IDVVDSNGAGDSFNAALAVALDEGLPISEAVLFANATAALCCMDWETVPSYRYREDVDAF
EEEECCCCCCCCCCEEEEEEECCCCCHHHHEEEECCCEEEEEECCCCCCCCHHHHHHHHH
MRSITVKEE
HHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]