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The map label for this gene is sirB1 [H]

Identifier: 51596334

GI number: 51596334

Start: 2363484

End: 2364293

Strand: Direct

Name: sirB1 [H]

Synonym: YPTB2008

Alternate gene names: 51596334

Gene position: 2363484-2364293 (Clockwise)

Preceding gene: 51596333

Following gene: 51596335

Centisome position: 49.81

GC content: 48.02

Gene sequence:

>810_bases
ATGAGTAGCATTGCTGATTTCGAATTTAATAACGCGTCCCTGTGTGATGGGGTGTTACTGGTTACCCAAGAGATTCGACA
GACTTTTCCGCTGGCTGATGTCCGTAACAAACTGCAGCAGCTTGTTGATGATGCGCGGGCCGCTATGCCTGCCGAACTTA
ATCAAGATCAGCAATTAGAAGTGCTTATCGATCTGTTTTACCGTCAATGGAAATTTGGCGGTGCAAGTGGTGTCTATCGC
CTGTCAGACGCCATCTGGTTAGATAAAGTGTTAGATAAACGCCAGGGGACACCGGTTTCTTTGGGGGTTATTTTTCTGTA
TATCGCGCATCAACTGGGTTTGCCGCTGATGCCGGTTATCTTCCCAACCCAGTTAATTCTTCGTGCCGATTGGCTAGATG
AAGAGATGTGGCTGATTAATCCGTTGAACGGTGAAACGCTGAACGAGCATGTGCTTGAAGTGTGGATCAAGGGCAATCTG
GGGTTGAGCGCCGAGCTGGAAGATGAAGATCTGGAAGAGGCAGAGAATACCCTTATTGTACGTAAAATGCTCGATACGCT
GAAAGCGGCATTAATGGAAGAGAAGCAGATGGAACTGGCATTACGTGCCAGCGAAGCGGTTTTGGCTTTCGACCCCGATG
ACCCGTATGAAATCCGCGACCGGGGCCTGATTTATGCGCAATTGGATTGCAACCACATTGCCATCTCTGATTTAAGCTAC
TTTGTCGAGCAGTGCCCGGAAGATCCGATTGCTGAAATGATAAAAATGCAGATCCACTCAATTGAGCAACAGCGAGTGAC
ATTGCACTGA

Upstream 100 bases:

>100_bases
GCCAGAATATTCGCTGGTTTGCCTTTATACTCGCACTGGGTTGCCTGTATCTAATTGTAAAACTGGCAACAACTAAATTA
CCACTGCTGATGGGATATCT

Downstream 100 bases:

>100_bases
TCTTTTTTATGCGCAGCGGTTTTATAGGGCAATAGCCCTCGTATACCATAATGCGCTGTAATTAATCTCGATTTACCCTT
TATAAAGGTATAAGTATGAA

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 269; Mature: 268

Protein sequence:

>269_residues
MSSIADFEFNNASLCDGVLLVTQEIRQTFPLADVRNKLQQLVDDARAAMPAELNQDQQLEVLIDLFYRQWKFGGASGVYR
LSDAIWLDKVLDKRQGTPVSLGVIFLYIAHQLGLPLMPVIFPTQLILRADWLDEEMWLINPLNGETLNEHVLEVWIKGNL
GLSAELEDEDLEEAENTLIVRKMLDTLKAALMEEKQMELALRASEAVLAFDPDDPYEIRDRGLIYAQLDCNHIAISDLSY
FVEQCPEDPIAEMIKMQIHSIEQQRVTLH

Sequences:

>Translated_269_residues
MSSIADFEFNNASLCDGVLLVTQEIRQTFPLADVRNKLQQLVDDARAAMPAELNQDQQLEVLIDLFYRQWKFGGASGVYR
LSDAIWLDKVLDKRQGTPVSLGVIFLYIAHQLGLPLMPVIFPTQLILRADWLDEEMWLINPLNGETLNEHVLEVWIKGNL
GLSAELEDEDLEEAENTLIVRKMLDTLKAALMEEKQMELALRASEAVLAFDPDDPYEIRDRGLIYAQLDCNHIAISDLSY
FVEQCPEDPIAEMIKMQIHSIEQQRVTLH
>Mature_268_residues
SSIADFEFNNASLCDGVLLVTQEIRQTFPLADVRNKLQQLVDDARAAMPAELNQDQQLEVLIDLFYRQWKFGGASGVYRL
SDAIWLDKVLDKRQGTPVSLGVIFLYIAHQLGLPLMPVIFPTQLILRADWLDEEMWLINPLNGETLNEHVLEVWIKGNLG
LSAELEDEDLEEAENTLIVRKMLDTLKAALMEEKQMELALRASEAVLAFDPDDPYEIRDRGLIYAQLDCNHIAISDLSYF
VEQCPEDPIAEMIKMQIHSIEQQRVTLH

Specific function: Not essential for the expression of the invasive phenotype. Required for maximal expression of sirC [H]

COG id: COG2912

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0162 family [H]

Homologues:

Organism=Escherichia coli, GI1787465, Length=269, Percent_Identity=61.7100371747212, Blast_Score=348, Evalue=2e-97,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011990 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 30696; Mature: 30564

Theoretical pI: Translated: 4.13; Mature: 4.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSIADFEFNNASLCDGVLLVTQEIRQTFPLADVRNKLQQLVDDARAAMPAELNQDQQLE
CCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHH
VLIDLFYRQWKFGGASGVYRLSDAIWLDKVLDKRQGTPVSLGVIFLYIAHQLGLPLMPVI
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHH
FPTQLILRADWLDEEMWLINPLNGETLNEHVLEVWIKGNLGLSAELEDEDLEEAENTLIV
HHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHEEEECCCCCCCCCCHHHHHHHHHHHHH
RKMLDTLKAALMEEKQMELALRASEAVLAFDPDDPYEIRDRGLIYAQLDCNHIAISDLSY
HHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHCCCCEEEEEECCCEEEHHHHHH
FVEQCPEDPIAEMIKMQIHSIEQQRVTLH
HHHHCCCCHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SSIADFEFNNASLCDGVLLVTQEIRQTFPLADVRNKLQQLVDDARAAMPAELNQDQQLE
CCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHH
VLIDLFYRQWKFGGASGVYRLSDAIWLDKVLDKRQGTPVSLGVIFLYIAHQLGLPLMPVI
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHH
FPTQLILRADWLDEEMWLINPLNGETLNEHVLEVWIKGNLGLSAELEDEDLEEAENTLIV
HHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHEEEECCCCCCCCCCHHHHHHHHHHHHH
RKMLDTLKAALMEEKQMELALRASEAVLAFDPDDPYEIRDRGLIYAQLDCNHIAISDLSY
HHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHCCCCEEEEEECCCEEEHHHHHH
FVEQCPEDPIAEMIKMQIHSIEQQRVTLH
HHHHCCCCHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]