Click here to switch to the map view.

The map label for this gene is csd1 [H]

Identifier: 51594908

GI number: 51594908

Start: 658664

End: 659932

Strand: Direct

Name: csd1 [H]

Synonym: YPTB0557

Alternate gene names: 51594908

Gene position: 658664-659932 (Clockwise)

Preceding gene: 51594907

Following gene: 51594909

Centisome position: 13.88

GC content: 41.13

Gene sequence:

>1269_bases
ATGATTAGGACTAAAATAAATAGTGGTGGATTGGATGTGGATTTTATTCGCGATCAATTTCCGATTCTAAAAAAACAAAT
AAATGGTCACCCACTCGTTTATTTAGATAATGCATCCACTTGTCAAAAACCTCAGGCAGTAATCGATGCAATAACAAAAT
GTTATTGCGAGTATTATGCCAATGCACATCGGGGAGTACATACGCTCTCACAGTGTGCAACCACGGCTTTTGAACATGTG
AGAGAGCAAGTTCGTGATTTTCTTCATGCCCGATCTACAGATGAAGTTATTTTCACTCGAGGAACGACAGAAGCTATTAA
TTTAGTCGCGACAAGCTGGGGGAAGAGCTATTTGCATGAGGGTGATGAAGTCCTTATTTCGGCTCTTGAACATCATAGTA
ATCTTGTTCCCTGGCAGCAAATATGTAGGGTTACGGGGGCTCGGCTTAAAGTTTTGCCTATCGAACCATCAGGGGTATTA
CAGATAGATTCACTTGAGCATCTACTGAGTAACCGAACGCGGGTTTTAGCCCTTTCTCATGTATCTAATGTGCTGGGTAC
AATCAATCCATTAGCCGCTATCATTCAAAAGGTGAGGATATATGATCAAATGCAGCAAGGTAAAAAAGAAAAAACTATTG
TATTGATCGATGGCGCGCAGGCTGTACCACATATTTCCATTAATGTGCAGGAGTTAGATGCAGATTTTTACGCCTTTTCT
GGGCATAAGCTCTATGGTCCGAGCGGAATTGGTGTGTTGTATGGTCGTAATGACATTCTGCGGAAAATGCTCCCTTGGCA
ATACGGAGGTGGTATGGTGGCAGATGTTAGCTTTGAGCAGTCGACTTTTGTGGTTCCTCCACGCTGCTTTGAGGCAGGTA
CTGCAAATATTGCTGGCGTTATTGGGCTGGGAGCCGCAATTACATGGTTACAAAATCTGGGTATTGGTGTCATCGCCGAG
CATGAACAAATACTATTAAAATATGTAACCGATCAACTCTCACAATTCTCGTGTATTCGCATATTAGGTCAGGTACCACT
AAAAGCTGCTGTAGTAGCTTTTATTATTAAAGATATTCCGGCCAGAAATATTGGATTAGCATTAGATAAGCAAGGTATTG
CGGTACAGGTCGGGCGGCATTGTGCTCAACCATTAATGAATTTCTTTGGGCTACAAGAAACAGTCCGAGTTTCTTTTGCG
GTTTATAACACATTAGAAGAAATTGATGTCTTTATATCCGCGTTACATGAAATAATTAATCAACATTAA

Upstream 100 bases:

>100_bases
AAATTATAAGCTTACTAATATTTTTTAAAATATTATAATTGCTATTAATTAGAATATTTATTTTCATGAGTGTTTTGGTT
TTTTTATGCTGAGGTATTTT

Downstream 100 bases:

>100_bases
TTATTTCATCGACGAATAAATTACTGGTTACAGTAAGAGGTATTATATGAATATTGACTGGACGGGTGCAACTGATATTA
AAGCGCAATATGGATGTTTG

Product: cysteine desulfurase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 422; Mature: 422

Protein sequence:

>422_residues
MIRTKINSGGLDVDFIRDQFPILKKQINGHPLVYLDNASTCQKPQAVIDAITKCYCEYYANAHRGVHTLSQCATTAFEHV
REQVRDFLHARSTDEVIFTRGTTEAINLVATSWGKSYLHEGDEVLISALEHHSNLVPWQQICRVTGARLKVLPIEPSGVL
QIDSLEHLLSNRTRVLALSHVSNVLGTINPLAAIIQKVRIYDQMQQGKKEKTIVLIDGAQAVPHISINVQELDADFYAFS
GHKLYGPSGIGVLYGRNDILRKMLPWQYGGGMVADVSFEQSTFVVPPRCFEAGTANIAGVIGLGAAITWLQNLGIGVIAE
HEQILLKYVTDQLSQFSCIRILGQVPLKAAVVAFIIKDIPARNIGLALDKQGIAVQVGRHCAQPLMNFFGLQETVRVSFA
VYNTLEEIDVFISALHEIINQH

Sequences:

>Translated_422_residues
MIRTKINSGGLDVDFIRDQFPILKKQINGHPLVYLDNASTCQKPQAVIDAITKCYCEYYANAHRGVHTLSQCATTAFEHV
REQVRDFLHARSTDEVIFTRGTTEAINLVATSWGKSYLHEGDEVLISALEHHSNLVPWQQICRVTGARLKVLPIEPSGVL
QIDSLEHLLSNRTRVLALSHVSNVLGTINPLAAIIQKVRIYDQMQQGKKEKTIVLIDGAQAVPHISINVQELDADFYAFS
GHKLYGPSGIGVLYGRNDILRKMLPWQYGGGMVADVSFEQSTFVVPPRCFEAGTANIAGVIGLGAAITWLQNLGIGVIAE
HEQILLKYVTDQLSQFSCIRILGQVPLKAAVVAFIIKDIPARNIGLALDKQGIAVQVGRHCAQPLMNFFGLQETVRVSFA
VYNTLEEIDVFISALHEIINQH
>Mature_422_residues
MIRTKINSGGLDVDFIRDQFPILKKQINGHPLVYLDNASTCQKPQAVIDAITKCYCEYYANAHRGVHTLSQCATTAFEHV
REQVRDFLHARSTDEVIFTRGTTEAINLVATSWGKSYLHEGDEVLISALEHHSNLVPWQQICRVTGARLKVLPIEPSGVL
QIDSLEHLLSNRTRVLALSHVSNVLGTINPLAAIIQKVRIYDQMQQGKKEKTIVLIDGAQAVPHISINVQELDADFYAFS
GHKLYGPSGIGVLYGRNDILRKMLPWQYGGGMVADVSFEQSTFVVPPRCFEAGTANIAGVIGLGAAITWLQNLGIGVIAE
HEQILLKYVTDQLSQFSCIRILGQVPLKAAVVAFIIKDIPARNIGLALDKQGIAVQVGRHCAQPLMNFFGLQETVRVSFA
VYNTLEEIDVFISALHEIINQH

Specific function: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine [H]

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Homo sapiens, GI32307132, Length=274, Percent_Identity=28.4671532846715, Blast_Score=108, Evalue=8e-24,
Organism=Homo sapiens, GI156713448, Length=295, Percent_Identity=27.7966101694915, Blast_Score=90, Evalue=5e-18,
Organism=Escherichia coli, GI1787970, Length=409, Percent_Identity=48.1662591687042, Blast_Score=395, Evalue=1e-111,
Organism=Escherichia coli, GI1789175, Length=408, Percent_Identity=38.9705882352941, Blast_Score=290, Evalue=8e-80,
Organism=Escherichia coli, GI48994898, Length=403, Percent_Identity=23.5732009925558, Blast_Score=100, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI25143064, Length=314, Percent_Identity=25.4777070063694, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI193211090, Length=401, Percent_Identity=28.6783042394015, Blast_Score=90, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6319831, Length=304, Percent_Identity=26.9736842105263, Blast_Score=105, Evalue=1e-23,
Organism=Drosophila melanogaster, GI20129463, Length=309, Percent_Identity=28.4789644012945, Blast_Score=119, Evalue=3e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR010970
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 46652; Mature: 46652

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRTKINSGGLDVDFIRDQFPILKKQINGHPLVYLDNASTCQKPQAVIDAITKCYCEYYA
CCEEEECCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHH
NAHRGVHTLSQCATTAFEHVREQVRDFLHARSTDEVIFTRGTTEAINLVATSWGKSYLHE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHCHHHHHC
GDEVLISALEHHSNLVPWQQICRVTGARLKVLPIEPSGVLQIDSLEHLLSNRTRVLALSH
CHHHHHHHHHHCCCCCCHHHHHHHCCCEEEEEEECCCCCEEHHHHHHHHCCCCEEEEHHH
VSNVLGTINPLAAIIQKVRIYDQMQQGKKEKTIVLIDGAQAVPHISINVQELDADFYAFS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEEHHHHCCCEEEEC
GHKLYGPSGIGVLYGRNDILRKMLPWQYGGGMVADVSFEQSTFVVPPRCFEAGTANIAGV
CCEEECCCCCEEEECCHHHHHHHCCCCCCCCEEEEEEECCCEEECCCHHHCCCCCCHHHH
IGLGAAITWLQNLGIGVIAEHEQILLKYVTDQLSQFSCIRILGQVPLKAAVVAFIIKDIP
HHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCC
ARNIGLALDKQGIAVQVGRHCAQPLMNFFGLQETVRVSFAVYNTLEEIDVFISALHEIIN
CCCCCEEECCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QH
CC
>Mature Secondary Structure
MIRTKINSGGLDVDFIRDQFPILKKQINGHPLVYLDNASTCQKPQAVIDAITKCYCEYYA
CCEEEECCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHH
NAHRGVHTLSQCATTAFEHVREQVRDFLHARSTDEVIFTRGTTEAINLVATSWGKSYLHE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHCHHHHHC
GDEVLISALEHHSNLVPWQQICRVTGARLKVLPIEPSGVLQIDSLEHLLSNRTRVLALSH
CHHHHHHHHHHCCCCCCHHHHHHHCCCEEEEEEECCCCCEEHHHHHHHHCCCCEEEEHHH
VSNVLGTINPLAAIIQKVRIYDQMQQGKKEKTIVLIDGAQAVPHISINVQELDADFYAFS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEEHHHHCCCEEEEC
GHKLYGPSGIGVLYGRNDILRKMLPWQYGGGMVADVSFEQSTFVVPPRCFEAGTANIAGV
CCEEECCCCCEEEECCHHHHHHHCCCCCCCCEEEEEEECCCEEECCCHHHCCCCCCHHHH
IGLGAAITWLQNLGIGVIAEHEQILLKYVTDQLSQFSCIRILGQVPLKAAVVAFIIKDIP
HHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCC
ARNIGLALDKQGIAVQVGRHCAQPLMNFFGLQETVRVSFAVYNTLEEIDVFISALHEIIN
CCCCCEEECCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QH
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]