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The map label for this gene is hflC

Identifier: 51594780

GI number: 51594780

Start: 512442

End: 513446

Strand: Direct

Name: hflC

Synonym: YPTB0428

Alternate gene names: 51594780

Gene position: 512442-513446 (Clockwise)

Preceding gene: 51594779

Following gene: 51594781

Centisome position: 10.8

GC content: 50.25

Gene sequence:

>1005_bases
ATGCGTAAGTCTTTTTTACTTATCGTCGTTGTGGTGTTAATCGCACTCTTCGCTTCGCTGTTTGTCGTAGAAGAAGGTCA
ACGCGGAATTGTGCTGCGCTTTGGTAAGGTATTACGTGATAGTGATAACAAACCGTTGGTGTATGCGCCTGGTCTGCACT
TCAAAATACCTTTTATCGAGACAGTGAAAAGGTTGGATGCCCGTATTCAAACCATGGACAACCAAGCTGACCGTTTCGTG
ACCAACGAGAAGAAAGACCTGATTGTTGACTCATACCTGAAATGGCGTATCAGCGATTTTAGTCGTTACTATCTGGCCAC
CGGTGGTGGTGATGTTTCTCAGGCCGAAGTTCTGCTGAAACGTAAGTTCAGTGACCGTTTGCGTTCTGAAATTGGCCGTT
TGAACGTCAGAGACATCGTGACAGACTCTCGTGGTCGATTGACTTCAGATGTTCGTGACGCCTTGAACACGGGTAGTGTG
GGCGATGAGGCCGCAACGACTGAAGCCGATGATGCGATTGCCTCTGCTGCAGCCAGAGTTGAGCAGGAAACCCGTGGCAA
ACAGCCTGCGGTTAACCCGAACAGCATGGCGGCCTTAGGGATTGAAGTGGTTGACGTGCGAATTAAGCAAATCAACTTAC
CTGCTGAAGTTTCTGATGCGATCTTCCAGCGCATGCGTGCAGAGCGTGAAGCGGTAGCCCGTCGTCACCGTTCACAAGGT
CAGGAAGAGGCCGAGAAATTGCGTGCGACTGCGGACTATGAAGTCACACGTACTCTGGCAGAAGCAGAGCGTCAGGCGCG
AATTACGCGTGGTGGCGGTGATGCAGAAGCGGCTCGTCTATTCGCTGAAGCATTTAGCCAAGATCCTGACTTCTATGCCT
TCATCCGTAGCTTGCGTGCGTATGAGAACAGCTTCAGCAGTGGTAACGATGTGATGGTTCTGAGCCCAGATAGCGATTTC
TTCCGCTATATGAAATCGCCAGACAACTCTAGCAAACGTCCATAA

Upstream 100 bases:

>100_bases
GAGTAATTCAAATACCAGCTCAGGCAGTGGTTCTATCATGGATCAGCGCCGGGTGAATGCTCAGCGTGATACTTCCACTC
GCGTAGGGAGAGAATAACCA

Downstream 100 bases:

>100_bases
CGACAGTTGCAGAGAGTATGGTGATAGCGCGGGCTGTAGCAGTGCCTATCATAGCCGTGAATCGTGCTGTCACCGTGCAT
ATTGCTAGAGTACGTTCTTG

Product: FtsH protease regulator HflC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MRKSFLLIVVVVLIALFASLFVVEEGQRGIVLRFGKVLRDSDNKPLVYAPGLHFKIPFIETVKRLDARIQTMDNQADRFV
TNEKKDLIVDSYLKWRISDFSRYYLATGGGDVSQAEVLLKRKFSDRLRSEIGRLNVRDIVTDSRGRLTSDVRDALNTGSV
GDEAATTEADDAIASAAARVEQETRGKQPAVNPNSMAALGIEVVDVRIKQINLPAEVSDAIFQRMRAEREAVARRHRSQG
QEEAEKLRATADYEVTRTLAEAERQARITRGGGDAEAARLFAEAFSQDPDFYAFIRSLRAYENSFSSGNDVMVLSPDSDF
FRYMKSPDNSSKRP

Sequences:

>Translated_334_residues
MRKSFLLIVVVVLIALFASLFVVEEGQRGIVLRFGKVLRDSDNKPLVYAPGLHFKIPFIETVKRLDARIQTMDNQADRFV
TNEKKDLIVDSYLKWRISDFSRYYLATGGGDVSQAEVLLKRKFSDRLRSEIGRLNVRDIVTDSRGRLTSDVRDALNTGSV
GDEAATTEADDAIASAAARVEQETRGKQPAVNPNSMAALGIEVVDVRIKQINLPAEVSDAIFQRMRAEREAVARRHRSQG
QEEAEKLRATADYEVTRTLAEAERQARITRGGGDAEAARLFAEAFSQDPDFYAFIRSLRAYENSFSSGNDVMVLSPDSDF
FRYMKSPDNSSKRP
>Mature_334_residues
MRKSFLLIVVVVLIALFASLFVVEEGQRGIVLRFGKVLRDSDNKPLVYAPGLHFKIPFIETVKRLDARIQTMDNQADRFV
TNEKKDLIVDSYLKWRISDFSRYYLATGGGDVSQAEVLLKRKFSDRLRSEIGRLNVRDIVTDSRGRLTSDVRDALNTGSV
GDEAATTEADDAIASAAARVEQETRGKQPAVNPNSMAALGIEVVDVRIKQINLPAEVSDAIFQRMRAEREAVARRHRSQG
QEEAEKLRATADYEVTRTLAEAERQARITRGGGDAEAARLFAEAFSQDPDFYAFIRSLRAYENSFSSGNDVMVLSPDSDF
FRYMKSPDNSSKRP

Specific function: HflC and HflK govern the stability of phage lambda cII protein and have been proposed to encode or regulate a cII- specific protease [H]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790617, Length=334, Percent_Identity=81.7365269461078, Blast_Score=531, Evalue=1e-152,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR010200
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7 [H]

EC number: 3.4.-.-

Molecular weight: Translated: 37438; Mature: 37438

Theoretical pI: Translated: 8.72; Mature: 8.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKSFLLIVVVVLIALFASLFVVEEGQRGIVLRFGKVLRDSDNKPLVYAPGLHFKIPFIE
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCEEECCCCCEECCHHH
TVKRLDARIQTMDNQADRFVTNEKKDLIVDSYLKWRISDFSRYYLATGGGDVSQAEVLLK
HHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHH
RKFSDRLRSEIGRLNVRDIVTDSRGRLTSDVRDALNTGSVGDEAATTEADDAIASAAARV
HHHHHHHHHHHCCCCHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHH
EQETRGKQPAVNPNSMAALGIEVVDVRIKQINLPAEVSDAIFQRMRAEREAVARRHRSQG
HHHHCCCCCCCCCCCHHHHHHHEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCC
QEEAEKLRATADYEVTRTLAEAERQARITRGGGDAEAARLFAEAFSQDPDFYAFIRSLRA
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHH
YENSFSSGNDVMVLSPDSDFFRYMKSPDNSSKRP
HHHCCCCCCEEEEECCCHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MRKSFLLIVVVVLIALFASLFVVEEGQRGIVLRFGKVLRDSDNKPLVYAPGLHFKIPFIE
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCEEECCCCCEECCHHH
TVKRLDARIQTMDNQADRFVTNEKKDLIVDSYLKWRISDFSRYYLATGGGDVSQAEVLLK
HHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHH
RKFSDRLRSEIGRLNVRDIVTDSRGRLTSDVRDALNTGSVGDEAATTEADDAIASAAARV
HHHHHHHHHHHCCCCHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHH
EQETRGKQPAVNPNSMAALGIEVVDVRIKQINLPAEVSDAIFQRMRAEREAVARRHRSQG
HHHHCCCCCCCCCCCHHHHHHHEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCC
QEEAEKLRATADYEVTRTLAEAERQARITRGGGDAEAARLFAEAFSQDPDFYAFIRSLRA
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHH
YENSFSSGNDVMVLSPDSDFFRYMKSPDNSSKRP
HHHCCCCCCEEEEECCCHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]