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The map label for this gene is ccdA [H]

Identifier: 50841812

GI number: 50841812

Start: 375422

End: 376183

Strand: Direct

Name: ccdA [H]

Synonym: PPA0326

Alternate gene names: 50841812

Gene position: 375422-376183 (Clockwise)

Preceding gene: 50841811

Following gene: 50841813

Centisome position: 14.66

GC content: 60.89

Gene sequence:

>762_bases
GTGACGCCACTCGACCTGGGATCGTGGGCAGCCGGGGCACTGACTGGATCGATGGCCGGAGCGATCCCGGTGGCGGTATT
TGCCGGTTTGTTGTCCTTCTTTTCCCCTTGCGTCTTGCCTCTCATCCCTGGCTATCTCAGCTATGTGACAGGCCTGGGGG
CCGCAGACGTCATTGAAGGACAGCGTCGGGCACGTACTGTGGTGGGCACAGTCCTTTTCGTGGTGGGTTTCACCGTCGTC
TTCGTCGCTACTGGGACGATTATTGGCACCCTCGGCAAGGTACTCGTGGGCCATCGTCGCGCCATCGAGATCATCGTTGG
AGCGCTGACCGTCGTACTCGGGGCGATGTTTGCTGGGCTTGTTCCGCTAGGCCGGCGCGAACTGCGGATCCATCGTCTGC
CCCGAGCAGGGTTGGCCGCCGCACCGATTTTAGGAATCGTCTTCGGGCTGGGCTGGACCCCATGCATTGGGCCGGCGCTG
TCGGTGGTTTATGGGCTGTCCTTGACCCAGGGATCAGCGGTACGAGGTGCGGTACTGGCCATTTGCTACTCGTTGGGTTT
GGGAATTCCGTTTATTGCGGCGGCTGCTGCTGTGGTGTGGATGGGTCGCACGATTGACGCGATGCGGACCCACCAGCACG
GTGTACAGCGCTTCGGGGGAATACTCCTGATGACTGTTGGTGTGCTGTTGGTCACCGGATGGTGGGAATCGATTATGGCG
ATGCTACGAGCCTGGGCAGCTAAGTTCGGGGCGGTGATCTGA

Upstream 100 bases:

>100_bases
TCGTCATCGATCGCAAGGGCCGCTCGGCCGCCCGATTCGTGGGAGAGGTGAGCACCGCCACCCTGGTCCAGGCGATTAAT
GATGTTGCCAAGGAGAGCCA

Downstream 100 bases:

>100_bases
TGGGCGATTCCGTGACGGATTCGAAAGTGACGACGGCCTCACCGTCTGGGAACAGCGGGCTGGGTTTTCGCCCATTCATG
CGTTGGGTGTGGGGCCAGTT

Product: cytochrome c biogenesis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 253; Mature: 252

Protein sequence:

>253_residues
MTPLDLGSWAAGALTGSMAGAIPVAVFAGLLSFFSPCVLPLIPGYLSYVTGLGAADVIEGQRRARTVVGTVLFVVGFTVV
FVATGTIIGTLGKVLVGHRRAIEIIVGALTVVLGAMFAGLVPLGRRELRIHRLPRAGLAAAPILGIVFGLGWTPCIGPAL
SVVYGLSLTQGSAVRGAVLAICYSLGLGIPFIAAAAAVVWMGRTIDAMRTHQHGVQRFGGILLMTVGVLLVTGWWESIMA
MLRAWAAKFGAVI

Sequences:

>Translated_253_residues
MTPLDLGSWAAGALTGSMAGAIPVAVFAGLLSFFSPCVLPLIPGYLSYVTGLGAADVIEGQRRARTVVGTVLFVVGFTVV
FVATGTIIGTLGKVLVGHRRAIEIIVGALTVVLGAMFAGLVPLGRRELRIHRLPRAGLAAAPILGIVFGLGWTPCIGPAL
SVVYGLSLTQGSAVRGAVLAICYSLGLGIPFIAAAAAVVWMGRTIDAMRTHQHGVQRFGGILLMTVGVLLVTGWWESIMA
MLRAWAAKFGAVI
>Mature_252_residues
TPLDLGSWAAGALTGSMAGAIPVAVFAGLLSFFSPCVLPLIPGYLSYVTGLGAADVIEGQRRARTVVGTVLFVVGFTVVF
VATGTIIGTLGKVLVGHRRAIEIIVGALTVVLGAMFAGLVPLGRRELRIHRLPRAGLAAAPILGIVFGLGWTPCIGPALS
VVYGLSLTQGSAVRGAVLAICYSLGLGIPFIAAAAAVVWMGRTIDAMRTHQHGVQRFGGILLMTVGVLLVTGWWESIMAM
LRAWAAKFGAVI

Specific function: Cytochrome c oxidase activity is partially restored by mutations in bdbC or bdbD that are defective in the synthesis of disulfide bond containing proteins. The same mutations abrogate the need for CcdA in sporulation [H]

COG id: COG0785

COG function: function code O; Cytochrome c biogenesis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DsbD family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834 [H]

Pfam domain/function: PF02683 DsbD [H]

EC number: NA

Molecular weight: Translated: 26160; Mature: 26029

Theoretical pI: Translated: 11.25; Mature: 11.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHCCCC
>Mature Secondary Structure 
TPLDLGSWAAGALTGSMAGAIPVAVFAGLLSFFSPCVLPLIPGYLSYVTGLGAADVIEG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
QRRARTVVGTVLFVVGFTVVFVATGTIIGTLGKVLVGHRRAIEIIVGALTVVLGAMFAGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VPLGRRELRIHRLPRAGLAAAPILGIVFGLGWTPCIGPALSVVYGLSLTQGSAVRGAVLA
CCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHH
ICYSLGLGIPFIAAAAAVVWMGRTIDAMRTHQHGVQRFGGILLMTVGVLLVTGWWESIMA
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLRAWAAKFGAVI
HHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8969507; 9068642; 9384377; 10781554; 11844773 [H]