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The map label for this gene is ppa [H]

Identifier: 50841746

GI number: 50841746

Start: 309691

End: 310323

Strand: Reverse

Name: ppa [H]

Synonym: PPA0256

Alternate gene names: 50841746

Gene position: 310323-309691 (Counterclockwise)

Preceding gene: 50841755

Following gene: 50841745

Centisome position: 12.12

GC content: 58.93

Gene sequence:

>633_bases
GTGTGGCACGAAAATCCCTCCTGCAAACGGATACAGTGTCGATCATCACCGTGTCCAATACAAGAAGAGGGGCCCCTCGT
GACCGACGATTTCACCAATCCATTCCAGGGAGAACAGCCTGAGAGCTTGCACTTCGATGTGACGATCGAGATTCCACGTG
GCAACAAGAATAAGTACGAGATGGACCATGAGACCGGTCGCATCCGTCTCGACCGCACCTTGTTCACCTCTACGCAGTAC
CCGTATGACTACGGATACATCGAGGGCACCCTCGGCGAGGACGGCGACCCGCTTGACGCCCTTGTCCTGCTGACTGAGCC
CACATTCCCCGGCTGCCTCATCGAGTGCCGCGCACTGGCTATGTTCCAGATGCAAGACGAGATGGGTGGCGACGACAAGG
TGCTGTGCGTGCCTGCCGATGACCCCCGCCGCGCCGGCCTCATCGACCTTGACGATGTCGGCAGCATGACCCTCATGGAA
ATCGAGCACTTCTTTACTGTCTACAAAGACCTGGAGCCCGGAAAGTCGGTCGAAGGAGCCACTTGGACCGATCGCGACGA
GGCTGAGGCCGAGATCAAGGCTTCCTTCGAGCGCGCCAAGGGCACCTCCTACGAGAACCTGCACACCGCCTGA

Upstream 100 bases:

>100_bases
CAACAATGACGACCACTGCGATGCCGACAGTAACGGGTACCCATCCCGGCATGCGCCGTCGTGGCGCCGACATAACTCGC
TTCGACGTAGGTTGATCTGA

Downstream 100 bases:

>100_bases
TCCACTCGCACCCCGGCACCGCCCCAATTCCAGGCCGCGAGTCATGACGTCAGCATTCGACACCCGCATCACCGCGGATG
CCGAATGCTGTTCATGACAC

Product: inorganic pyrophosphatase

Products: NA

Alternate protein names: Pyrophosphate phospho-hydrolase; PPase [H]

Number of amino acids: Translated: 210; Mature: 210

Protein sequence:

>210_residues
MWHENPSCKRIQCRSSPCPIQEEGPLVTDDFTNPFQGEQPESLHFDVTIEIPRGNKNKYEMDHETGRIRLDRTLFTSTQY
PYDYGYIEGTLGEDGDPLDALVLLTEPTFPGCLIECRALAMFQMQDEMGGDDKVLCVPADDPRRAGLIDLDDVGSMTLME
IEHFFTVYKDLEPGKSVEGATWTDRDEAEAEIKASFERAKGTSYENLHTA

Sequences:

>Translated_210_residues
MWHENPSCKRIQCRSSPCPIQEEGPLVTDDFTNPFQGEQPESLHFDVTIEIPRGNKNKYEMDHETGRIRLDRTLFTSTQY
PYDYGYIEGTLGEDGDPLDALVLLTEPTFPGCLIECRALAMFQMQDEMGGDDKVLCVPADDPRRAGLIDLDDVGSMTLME
IEHFFTVYKDLEPGKSVEGATWTDRDEAEAEIKASFERAKGTSYENLHTA
>Mature_210_residues
MWHENPSCKRIQCRSSPCPIQEEGPLVTDDFTNPFQGEQPESLHFDVTIEIPRGNKNKYEMDHETGRIRLDRTLFTSTQY
PYDYGYIEGTLGEDGDPLDALVLLTEPTFPGCLIECRALAMFQMQDEMGGDDKVLCVPADDPRRAGLIDLDDVGSMTLME
IEHFFTVYKDLEPGKSVEGATWTDRDEAEAEIKASFERAKGTSYENLHTA

Specific function: Unknown

COG id: COG0221

COG function: function code C; Inorganic pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PPase family [H]

Homologues:

Organism=Escherichia coli, GI1790673, Length=171, Percent_Identity=42.1052631578947, Blast_Score=127, Evalue=7e-31,

Paralogues:

None

Copy number: 5480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008162 [H]

Pfam domain/function: PF00719 Pyrophosphatase [H]

EC number: =3.6.1.1 [H]

Molecular weight: Translated: 23738; Mature: 23738

Theoretical pI: Translated: 4.14; Mature: 4.14

Prosite motif: PS00387 PPASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWHENPSCKRIQCRSSPCPIQEEGPLVTDDFTNPFQGEQPESLHFDVTIEIPRGNKNKYE
CCCCCCCCCEEEECCCCCCCCCCCCEEECCCCCCCCCCCCCCEEEEEEEEECCCCCCCEE
MDHETGRIRLDRTLFTSTQYPYDYGYIEGTLGEDGDPLDALVLLTEPTFPGCLIECRALA
ECCCCCEEEEEEEEEECCCCCCCCCEEEECCCCCCCCCEEEEEEECCCCCCHHHHHHHHH
MFQMQDEMGGDDKVLCVPADDPRRAGLIDLDDVGSMTLMEIEHFFTVYKDLEPGKSVEGA
HHHHHHHCCCCCCEEEEECCCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCC
TWTDRDEAEAEIKASFERAKGTSYENLHTA
CCCCCCCHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MWHENPSCKRIQCRSSPCPIQEEGPLVTDDFTNPFQGEQPESLHFDVTIEIPRGNKNKYE
CCCCCCCCCEEEECCCCCCCCCCCCEEECCCCCCCCCCCCCCEEEEEEEEECCCCCCCEE
MDHETGRIRLDRTLFTSTQYPYDYGYIEGTLGEDGDPLDALVLLTEPTFPGCLIECRALA
ECCCCCEEEEEEEEEECCCCCCCCCEEEECCCCCCCCCEEEEEEECCCCCCHHHHHHHHH
MFQMQDEMGGDDKVLCVPADDPRRAGLIDLDDVGSMTLMEIEHFFTVYKDLEPGKSVEGA
HHHHHHHCCCCCCEEEEECCCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCC
TWTDRDEAEAEIKASFERAKGTSYENLHTA
CCCCCCCHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]