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The map label for this gene is yprA [H]

Identifier: 50841730

GI number: 50841730

Start: 287834

End: 290098

Strand: Reverse

Name: yprA [H]

Synonym: PPA0237

Alternate gene names: 50841730

Gene position: 290098-287834 (Counterclockwise)

Preceding gene: 50841741

Following gene: 50841721

Centisome position: 11.33

GC content: 62.74

Gene sequence:

>2265_bases
GTGTCGCGGCTGTTGACCAGCCCCCAGGTGGTCTATCTTGATCATCGCGAGGCCGCAGCAGGACACACCTGCGAGTGGCC
TTCGTGGTTCCCCGAGGATTGTCGTCAAGCCGTCGAAGCGGCTGGGATTCATCGGCCATGGCAACACCAGGCGCGATTCG
CCGAGCTGGCAAGAGCAGGCCGTCATGCAGCGATCTGTACCGCAACGGCGTCGGGAAAAACCTTGGCCTATTTGTTGCCG
ATCATGGCTGCGACGGCATCGGCCACCCCGGTGGTGCCGGAGTCGCCAACTCCTGGCCTGCCGGCATCTTTGCGGGATTC
CCTACACCGCAACAGTGCCCTGTACCTGGCTCCCACGAAGGCCCTGGCTCACGACCAAGAACGCGTTTGCCGCGAGGTTG
GGCCGAGGGATTGGCTGGTTTCGACCCTTGACGGCGATTCCGATGAGGCTGAGCGTCGTTTCGCCCGGGAGCAGGCCCGA
TACGTCCTCACGAACCCGGACATGTTGCACCACACGGTGCTGCCGTCTCATGCACGGTGGGCTGGGTTGCTCGGAAGCCT
GCGATATGTCGTCATTGATGAAGCCCACCGATATCGCGGGGTCTTCGGGGCACACGTGGCCCAGGTTATTCGCCGGCTGC
GCAGGCTTTGTCGGATGCATGGCGCAGATCCGGTATTCCTGCTTTCTAGCGCGACCTCGACGAACGCAGCCGAAGCCGGG
ACCCGCCTGCTCGGGGTAGAGAAGGTCGAGGTCGTTGATGAGGATTGCTCCCCACACCCGGGCCGTGACGTCGTCTTGTG
GCAGCCAGCCGAGTCCATCTCAACCGATGCGACGGGGCTTGTAGCTGACCTGGCCGACGCCGGATTACAGACGATCTGTT
TCGTCGCCTCGCGTTCGCTGGCAGAGGTCATTTCTGCCCATGCCCAGGACCGGGTAACTAGCGGCGCTCGGGTTACCGCG
TATCGGGCTGGGTACCTTCCCGAGGACCGACGACGTATCGAGGCCAGACTGCAGGACGGCTCGGTGCGAGCGGTCGTCGC
AACGAATGCCCTGGAGCTGGGTGTAGACATTTCGGGGATGGACGCTGTCGTTATCGCCGGGTATCCGGGACGACTGTCGG
CCTTGTGGCAGCAGGCTGGTCGAGCCGGACGGTCGGGCCGTGACGCGTTGGTGGTGCTCATGGCCCGGGAAAATCCGCTG
GATCAATACCTCTTTGAGCACCCCGAATTATTGTTCTCGTCCTCGGTGGAATCGACTGTGTTGCACCCGGATAACCCGTA
TGTGCTCGGCCCGCACGTGGCCGCGGCCGCCCAGGAGGCATACCTCTCCCCTGCGGACGAAGAGTTTTACGGGTCGGCCT
TTGCCGGGATATGCAAAACGCTGACAGGCCAGAACGTACTGCGACGTCGCGGAAATCGGCTGTTCTGGACCCGTCCAGAA
CGGGCTGTCGACGCCATCGACCTGCGATCGGCGGCAGGCAAAGGGATTGACATTATCGACGTGTCCACGGGGAGGGTCAT
CGGGGGAGTCGACGAAGCCGCCGCAGACCGTACCGTGCATCCAGGCGCGGTGTACCTGCATCAGGGGGATCAATGGCTGG
TCGACGAATACAACCCGGTCGAGCACCACGCCCTGGTGCACCAGGACCTGCCGGGATATTGGACTCAACCGCAGTCAGCG
TCGACGGTGAGAATCCTTCGGGAGGAGAGACGTCGCGCTTGTGGTCCCGGATATGTGGCGTGCGGGCAGGTGGAACTGAC
AGAGCAAGTTGTTGGGTATCTGCGTCGCGACGAAATCACCAATGATGTGTGGGACTCGGTGGCCCTCGAGATGCCCACCC
ACACCATGATCACCCAGGCCTGCTGGTGGGTTATTCCCGACAAAGTTGTGGACGACCTGAAGTTCGATGCCGTCCATCTG
GCAGGGGCCGCCCATGGCGCTGAGCACACCGCGATTGGACTACTGCCAATGTACTCACCGTGCGACCGATGGGATGTGGG
TGGGGTGTCGACGGTGATGTTGCCTGACACTGGAGCGTGCACCATCGTCGTCCACGACGGTCAGGCCGGTGGGGCTGGAT
TCGCCGAGGCCGGTTTCGAGAAGGCCGAGGAATGGTGGCATGCCACCATCATGCGCCTAGCCCAATGTGGATGTGAGTCT
GGATGCCCCGCCTGCGTCGTCTCGCCCAAATGCGGGAATGCCAACCAAATGCTCGATAAGGCCGCTGCTGCCGCACTGAC
GGCAGCGATGGATCCGCTGGCCTAA

Upstream 100 bases:

>100_bases
ATGTGCCGCAGCTGTTCGATCTCGTCGACGGTGAGGTGTCTGCCCATGGTGGCAATCTTGGCGCGTGATCGTTCCATCTG
TCTCGTCAACCCGTGACGCT

Downstream 100 bases:

>100_bases
TCGGTCATTCGACATAGTTTATGGTGCGGCTTCGGTATCCCCTCCTCGCGGATGTTTGTGTTACCGCCCCTGCAACATCC
CCAGCACTACTCTGGGCAGC

Product: putative helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 754; Mature: 753

Protein sequence:

>754_residues
MSRLLTSPQVVYLDHREAAAGHTCEWPSWFPEDCRQAVEAAGIHRPWQHQARFAELARAGRHAAICTATASGKTLAYLLP
IMAATASATPVVPESPTPGLPASLRDSLHRNSALYLAPTKALAHDQERVCREVGPRDWLVSTLDGDSDEAERRFAREQAR
YVLTNPDMLHHTVLPSHARWAGLLGSLRYVVIDEAHRYRGVFGAHVAQVIRRLRRLCRMHGADPVFLLSSATSTNAAEAG
TRLLGVEKVEVVDEDCSPHPGRDVVLWQPAESISTDATGLVADLADAGLQTICFVASRSLAEVISAHAQDRVTSGARVTA
YRAGYLPEDRRRIEARLQDGSVRAVVATNALELGVDISGMDAVVIAGYPGRLSALWQQAGRAGRSGRDALVVLMARENPL
DQYLFEHPELLFSSSVESTVLHPDNPYVLGPHVAAAAQEAYLSPADEEFYGSAFAGICKTLTGQNVLRRRGNRLFWTRPE
RAVDAIDLRSAAGKGIDIIDVSTGRVIGGVDEAAADRTVHPGAVYLHQGDQWLVDEYNPVEHHALVHQDLPGYWTQPQSA
STVRILREERRRACGPGYVACGQVELTEQVVGYLRRDEITNDVWDSVALEMPTHTMITQACWWVIPDKVVDDLKFDAVHL
AGAAHGAEHTAIGLLPMYSPCDRWDVGGVSTVMLPDTGACTIVVHDGQAGGAGFAEAGFEKAEEWWHATIMRLAQCGCES
GCPACVVSPKCGNANQMLDKAAAAALTAAMDPLA

Sequences:

>Translated_754_residues
MSRLLTSPQVVYLDHREAAAGHTCEWPSWFPEDCRQAVEAAGIHRPWQHQARFAELARAGRHAAICTATASGKTLAYLLP
IMAATASATPVVPESPTPGLPASLRDSLHRNSALYLAPTKALAHDQERVCREVGPRDWLVSTLDGDSDEAERRFAREQAR
YVLTNPDMLHHTVLPSHARWAGLLGSLRYVVIDEAHRYRGVFGAHVAQVIRRLRRLCRMHGADPVFLLSSATSTNAAEAG
TRLLGVEKVEVVDEDCSPHPGRDVVLWQPAESISTDATGLVADLADAGLQTICFVASRSLAEVISAHAQDRVTSGARVTA
YRAGYLPEDRRRIEARLQDGSVRAVVATNALELGVDISGMDAVVIAGYPGRLSALWQQAGRAGRSGRDALVVLMARENPL
DQYLFEHPELLFSSSVESTVLHPDNPYVLGPHVAAAAQEAYLSPADEEFYGSAFAGICKTLTGQNVLRRRGNRLFWTRPE
RAVDAIDLRSAAGKGIDIIDVSTGRVIGGVDEAAADRTVHPGAVYLHQGDQWLVDEYNPVEHHALVHQDLPGYWTQPQSA
STVRILREERRRACGPGYVACGQVELTEQVVGYLRRDEITNDVWDSVALEMPTHTMITQACWWVIPDKVVDDLKFDAVHL
AGAAHGAEHTAIGLLPMYSPCDRWDVGGVSTVMLPDTGACTIVVHDGQAGGAGFAEAGFEKAEEWWHATIMRLAQCGCES
GCPACVVSPKCGNANQMLDKAAAAALTAAMDPLA
>Mature_753_residues
SRLLTSPQVVYLDHREAAAGHTCEWPSWFPEDCRQAVEAAGIHRPWQHQARFAELARAGRHAAICTATASGKTLAYLLPI
MAATASATPVVPESPTPGLPASLRDSLHRNSALYLAPTKALAHDQERVCREVGPRDWLVSTLDGDSDEAERRFAREQARY
VLTNPDMLHHTVLPSHARWAGLLGSLRYVVIDEAHRYRGVFGAHVAQVIRRLRRLCRMHGADPVFLLSSATSTNAAEAGT
RLLGVEKVEVVDEDCSPHPGRDVVLWQPAESISTDATGLVADLADAGLQTICFVASRSLAEVISAHAQDRVTSGARVTAY
RAGYLPEDRRRIEARLQDGSVRAVVATNALELGVDISGMDAVVIAGYPGRLSALWQQAGRAGRSGRDALVVLMARENPLD
QYLFEHPELLFSSSVESTVLHPDNPYVLGPHVAAAAQEAYLSPADEEFYGSAFAGICKTLTGQNVLRRRGNRLFWTRPER
AVDAIDLRSAAGKGIDIIDVSTGRVIGGVDEAAADRTVHPGAVYLHQGDQWLVDEYNPVEHHALVHQDLPGYWTQPQSAS
TVRILREERRRACGPGYVACGQVELTEQVVGYLRRDEITNDVWDSVALEMPTHTMITQACWWVIPDKVVDDLKFDAVHLA
GAAHGAEHTAIGLLPMYSPCDRWDVGGVSTVMLPDTGACTIVVHDGQAGGAGFAEAGFEKAEEWWHATIMRLAQCGCESG
CPACVVSPKCGNANQMLDKAAAAALTAAMDPLA

Specific function: Unknown

COG id: COG1205

COG function: function code R; Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1787942, Length=452, Percent_Identity=28.0973451327434, Blast_Score=71, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6320497, Length=754, Percent_Identity=29.1777188328912, Blast_Score=342, Evalue=2e-94,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR018973
- InterPro:   IPR011545
- InterPro:   IPR001650
- InterPro:   IPR014021 [H]

Pfam domain/function: PF00270 DEAD; PF09369 DUF1998; PF00271 Helicase_C [H]

EC number: 3.6.1.- [C]

Molecular weight: Translated: 81711; Mature: 81580

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRLLTSPQVVYLDHREAAAGHTCEWPSWFPEDCRQAVEAAGIHRPWQHQARFAELARAG
CCCCCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCC
RHAAICTATASGKTLAYLLPIMAATASATPVVPESPTPGLPASLRDSLHRNSALYLAPTK
CCEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCCEEEEECCH
ALAHDQERVCREVGPRDWLVSTLDGDSDEAERRFAREQARYVLTNPDMLHHTVLPSHARW
HHHCCHHHHHHHCCCCHHEEEECCCCCHHHHHHHHHHHCCEEECCCCHHHHCCCCCHHHH
AGLLGSLRYVVIDEAHRYRGVFGAHVAQVIRRLRRLCRMHGADPVFLLSSATSTNAAEAG
HHHHHCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHC
TRLLGVEKVEVVDEDCSPHPGRDVVLWQPAESISTDATGLVADLADAGLQTICFVASRSL
HHHCCCCCEEEECCCCCCCCCCEEEEECCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
AEVISAHAQDRVTSGARVTAYRAGYLPEDRRRIEARLQDGSVRAVVATNALELGVDISGM
HHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHCCCCEEEEEEECCEEECCEECCC
DAVVIAGYPGRLSALWQQAGRAGRSGRDALVVLMARENPLDQYLFEHPELLFSSSVESTV
CEEEEECCCHHHHHHHHHHHCCCCCCCCEEEEEEECCCCHHHHHHHCCHHHHHCCCCCEE
LHPDNPYVLGPHVAAAAQEAYLSPADEEFYGSAFAGICKTLTGQNVLRRRGNRLFWTRPE
ECCCCCEEECCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHCCCEEEEECCH
RAVDAIDLRSAAGKGIDIIDVSTGRVIGGVDEAAADRTVHPGAVYLHQGDQWLVDEYNPV
HHHHHHHHHHHCCCCCEEEEECCCCEECCCCHHHCCCCCCCCEEEEECCCEEECCCCCCH
EHHALVHQDLPGYWTQPQSASTVRILREERRRACGPGYVACGQVELTEQVVGYLRRDEIT
HHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEECCEEHHHHHHHHHHHHHHH
NDVWDSVALEMPTHTMITQACWWVIPDKVVDDLKFDAVHLAGAAHGAEHTAIGLLPMYSP
HHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHCCCCCEEEECCCCCCCCCEEEEEECCCC
CDRWDVGGVSTVMLPDTGACTIVVHDGQAGGAGFAEAGFEKAEEWWHATIMRLAQCGCES
CCCCCCCCEEEEEECCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
GCPACVVSPKCGNANQMLDKAAAAALTAAMDPLA
CCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SRLLTSPQVVYLDHREAAAGHTCEWPSWFPEDCRQAVEAAGIHRPWQHQARFAELARAG
CCCCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCC
RHAAICTATASGKTLAYLLPIMAATASATPVVPESPTPGLPASLRDSLHRNSALYLAPTK
CCEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCCEEEEECCH
ALAHDQERVCREVGPRDWLVSTLDGDSDEAERRFAREQARYVLTNPDMLHHTVLPSHARW
HHHCCHHHHHHHCCCCHHEEEECCCCCHHHHHHHHHHHCCEEECCCCHHHHCCCCCHHHH
AGLLGSLRYVVIDEAHRYRGVFGAHVAQVIRRLRRLCRMHGADPVFLLSSATSTNAAEAG
HHHHHCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHC
TRLLGVEKVEVVDEDCSPHPGRDVVLWQPAESISTDATGLVADLADAGLQTICFVASRSL
HHHCCCCCEEEECCCCCCCCCCEEEEECCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
AEVISAHAQDRVTSGARVTAYRAGYLPEDRRRIEARLQDGSVRAVVATNALELGVDISGM
HHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHCCCCEEEEEEECCEEECCEECCC
DAVVIAGYPGRLSALWQQAGRAGRSGRDALVVLMARENPLDQYLFEHPELLFSSSVESTV
CEEEEECCCHHHHHHHHHHHCCCCCCCCEEEEEEECCCCHHHHHHHCCHHHHHCCCCCEE
LHPDNPYVLGPHVAAAAQEAYLSPADEEFYGSAFAGICKTLTGQNVLRRRGNRLFWTRPE
ECCCCCEEECCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHCCCEEEEECCH
RAVDAIDLRSAAGKGIDIIDVSTGRVIGGVDEAAADRTVHPGAVYLHQGDQWLVDEYNPV
HHHHHHHHHHHCCCCCEEEEECCCCEECCCCHHHCCCCCCCCEEEEECCCEEECCCCCCH
EHHALVHQDLPGYWTQPQSASTVRILREERRRACGPGYVACGQVELTEQVVGYLRRDEIT
HHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEECCEEHHHHHHHHHHHHHHH
NDVWDSVALEMPTHTMITQACWWVIPDKVVDDLKFDAVHLAGAAHGAEHTAIGLLPMYSP
HHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHCCCCCEEEECCCCCCCCCEEEEEECCCC
CDRWDVGGVSTVMLPDTGACTIVVHDGQAGGAGFAEAGFEKAEEWWHATIMRLAQCGCES
CCCCCCCCEEEEEECCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
GCPACVVSPKCGNANQMLDKAAAAALTAAMDPLA
CCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on acid anhydrides [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8760912; 9384377 [H]