Click here to switch to the map view.

The map label for this gene is pyrD [H]

Identifier: 50841649

GI number: 50841649

Start: 191680

End: 192687

Strand: Reverse

Name: pyrD [H]

Synonym: PPA0161

Alternate gene names: 50841649

Gene position: 192687-191680 (Counterclockwise)

Preceding gene: 50841650

Following gene: 50841647

Centisome position: 7.53

GC content: 61.81

Gene sequence:

>1008_bases
ATGAGTGATCTTCACACCAAGTACATGGGGCTAACCCTGAGGTCGCCATTAGTTGCCTCCGCCGGCCCCATCCAGCAGAA
AGTCGACGGGGTCAGGGCCCTCGCCGACGCCGGGGTCGGAGCTATCGTCATGTACTCCCTATTCGAGGAACAGGTGAGGC
ACGAGGAGGCTCGGCAAGCCGAAATCGAGCTAGAGTACATGGACTCGTTCGCCGAATCGCTGAGCTTCTTCCCGACCGTG
GCCAGCAACGAAGGCGGCATTACCGAGCGCTACCTCGCCCATCTGGAAGCCAGCGCCAATGCCGTTGACATCCCCGTCAT
TGCGTCCCTCAACGGGGCCACAAACGGCGGCTGGGTCGACACCGCCAAACGGATGGAGAACGCCGGCGCAGCAGGCATCG
AGTGCAACATCTACATGGTGCCCGGTGACCTTGAACAGTCAGCCGAAGAAGTCGAAGACCGCCACGTCGAGATCGTCCAG
GCCGTCAAAGACGCCGTGAGCGTACCGGTTGCTGTCAAACTCTCGCCGTTCTTCTCGGCCCTCGGCAATATGGCTACCCG
CCTGGATGCCGCTGGTGCCGACGCCCTAGTGATGTTCAACCGGTTCCTGCAGCCCGACATCAACGTCGAGACAATGCAAG
TAGAGCCCGGGGTGTGGCTGTCTTCCCCGGCTGACGCTCGCCTGCCACTGACGTGGATTGCTGTACTGTCGGGCCGCATT
GGCGCCTCGCTGGCTGCGTCCTCAGGCGTCGAGAGCGCCAACGACGTCGTCAAGTACCTGCTTGCTGGAGCCGACGTCGT
TATGACCACTTCAGCGTTGGTGCGTCACGGCGCCGGGTACGCGACCGAGCTGCAGAAGGGACTGGAATCCTACCTGCAAC
GCAAGGAAGTCGACCTTGACACGCTGCGCGGAACGCTCGCTGTCCCGAACGATGCGTCGACCGCCGAGTACGAACGCAAC
GGTTACGTTGCGGCCCTCGAGAAGGCCAAAACAACCTATGGATCCTGA

Upstream 100 bases:

>100_bases
TGGCATCCCGCACCGCCGAGGACTTCGCCGTCGATGCCCGTATGTCCGAGTTCGCCGCTTCATCCAACCGCGCCTGACAG
CCACGAAGGAATGACGTGTC

Downstream 100 bases:

>100_bases
CCCTCGAATGTGCAGAAGGGCCGGTGGCGATCGTCACCGGCCCTTCGCTATGTCCGATACCTATCGCTGACAAGGGCACG
GGGATGCGCCTTGTCCGGAA

Product: dihydroorotate dehydrogenase 2

Products: NA

Alternate protein names: DHOdehase; DHOD; DHODase; Dihydroorotate oxidase [H]

Number of amino acids: Translated: 335; Mature: 334

Protein sequence:

>335_residues
MSDLHTKYMGLTLRSPLVASAGPIQQKVDGVRALADAGVGAIVMYSLFEEQVRHEEARQAEIELEYMDSFAESLSFFPTV
ASNEGGITERYLAHLEASANAVDIPVIASLNGATNGGWVDTAKRMENAGAAGIECNIYMVPGDLEQSAEEVEDRHVEIVQ
AVKDAVSVPVAVKLSPFFSALGNMATRLDAAGADALVMFNRFLQPDINVETMQVEPGVWLSSPADARLPLTWIAVLSGRI
GASLAASSGVESANDVVKYLLAGADVVMTTSALVRHGAGYATELQKGLESYLQRKEVDLDTLRGTLAVPNDASTAEYERN
GYVAALEKAKTTYGS

Sequences:

>Translated_335_residues
MSDLHTKYMGLTLRSPLVASAGPIQQKVDGVRALADAGVGAIVMYSLFEEQVRHEEARQAEIELEYMDSFAESLSFFPTV
ASNEGGITERYLAHLEASANAVDIPVIASLNGATNGGWVDTAKRMENAGAAGIECNIYMVPGDLEQSAEEVEDRHVEIVQ
AVKDAVSVPVAVKLSPFFSALGNMATRLDAAGADALVMFNRFLQPDINVETMQVEPGVWLSSPADARLPLTWIAVLSGRI
GASLAASSGVESANDVVKYLLAGADVVMTTSALVRHGAGYATELQKGLESYLQRKEVDLDTLRGTLAVPNDASTAEYERN
GYVAALEKAKTTYGS
>Mature_334_residues
SDLHTKYMGLTLRSPLVASAGPIQQKVDGVRALADAGVGAIVMYSLFEEQVRHEEARQAEIELEYMDSFAESLSFFPTVA
SNEGGITERYLAHLEASANAVDIPVIASLNGATNGGWVDTAKRMENAGAAGIECNIYMVPGDLEQSAEEVEDRHVEIVQA
VKDAVSVPVAVKLSPFFSALGNMATRLDAAGADALVMFNRFLQPDINVETMQVEPGVWLSSPADARLPLTWIAVLSGRIG
ASLAASSGVESANDVVKYLLAGADVVMTTSALVRHGAGYATELQKGLESYLQRKEVDLDTLRGTLAVPNDASTAEYERNG
YVAALEKAKTTYGS

Specific function: Unknown

COG id: COG0167

COG function: function code F; Dihydroorotate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR005720
- InterPro:   IPR012135
- InterPro:   IPR001295 [H]

Pfam domain/function: PF01180 DHO_dh [H]

EC number: =1.3.3.1 [H]

Molecular weight: Translated: 35690; Mature: 35558

Theoretical pI: Translated: 4.33; Mature: 4.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDLHTKYMGLTLRSPLVASAGPIQQKVDGVRALADAGVGAIVMYSLFEEQVRHEEARQA
CCCHHHHHHCEEECCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
EIELEYMDSFAESLSFFPTVASNEGGITERYLAHLEASANAVDIPVIASLNGATNGGWVD
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCHHH
TAKRMENAGAAGIECNIYMVPGDLEQSAEEVEDRHVEIVQAVKDAVSVPVAVKLSPFFSA
HHHHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHHH
LGNMATRLDAAGADALVMFNRFLQPDINVETMQVEPGVWLSSPADARLPLTWIAVLSGRI
HHHHHHHHHCCCCHHHHHHHHHCCCCCCEEEEEECCCCEECCCCCCCCHHHHHHHHHCCC
GASLAASSGVESANDVVKYLLAGADVVMTTSALVRHGAGYATELQKGLESYLQRKEVDLD
CCHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHH
TLRGTLAVPNDASTAEYERNGYVAALEKAKTTYGS
HHCCEEECCCCCCCCHHHCCCEEEEHHHHHHCCCC
>Mature Secondary Structure 
SDLHTKYMGLTLRSPLVASAGPIQQKVDGVRALADAGVGAIVMYSLFEEQVRHEEARQA
CCHHHHHHCEEECCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
EIELEYMDSFAESLSFFPTVASNEGGITERYLAHLEASANAVDIPVIASLNGATNGGWVD
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCHHH
TAKRMENAGAAGIECNIYMVPGDLEQSAEEVEDRHVEIVQAVKDAVSVPVAVKLSPFFSA
HHHHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHHH
LGNMATRLDAAGADALVMFNRFLQPDINVETMQVEPGVWLSSPADARLPLTWIAVLSGRI
HHHHHHHHHCCCCHHHHHHHHHCCCCCCEEEEEECCCCEECCCCCCCCHHHHHHHHHCCC
GASLAASSGVESANDVVKYLLAGADVVMTTSALVRHGAGYATELQKGLESYLQRKEVDLD
CCHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHH
TLRGTLAVPNDASTAEYERNGYVAALEKAKTTYGS
HHCCEEECCCCCCCCHHHCCCEEEEHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]