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The map label for this gene is glpR [H]

Identifier: 50841633

GI number: 50841633

Start: 172897

End: 173658

Strand: Reverse

Name: glpR [H]

Synonym: PPA0144

Alternate gene names: 50841633

Gene position: 173658-172897 (Counterclockwise)

Preceding gene: 50841640

Following gene: 50841632

Centisome position: 6.78

GC content: 60.37

Gene sequence:

>762_bases
GTGTATCCCGCCGAAAGACACAAGTGGCTGATCGATACTGCCCGCGAGACCGGTCGAGTATCGGTTGCTGAAGCCTCCAC
TGCACTAGGAGTTGTCCCCGAGACCATTCGCCGTGACCTCGACCAGTTGTGCAATCAGAAAATGCTGCGGCGGGTACACG
GTGGCGCTATCCCGATCGAGTTCGACCTGCTGGGCGACCAGCCCCTCGCCACCCGAGACTCCTCGGCAGTGACGCAGAAG
GAACAAATCGCCCGGGCGGCACTATCCCATCTACCTAGTGACAAGGGGTCAATCATCCTCGACGCCGGGTCGACAACCGG
CCGGTTAGCGTCGATCATGCCCTCCACAAGGCGATTCACCGTCTTTACGAACTCATCCCCAATCGCCAGCACGGTGGCTA
CCCACAGCAACTGTGACGTCCACCTGCTGGGAGGACGACTGCGCCCCACTACCCAGGCCACCGTCGGTAACGTTGACGCC
ATTGCCCGACTCCGCGTCGACGTTGCCTTCATGGGCACTAACGGCATTTCCCCGACGCACGGCTTATCCACTCCTGACGC
CGATGAAGTTGCAACTAAGGCGGCAATGGTCGCGAACGCCCATCACGTCGTAGTTCTGGCCGATTCTCGGAAGATGGGTG
CGGAATCGACGATGAGGTTCGCAGAGCTGGGCGACGTTGACGTCATCATCACCGACTCTGGGGTGACTCCTCACCAAGTC
GAGATGCTGCACAAGGCTGGCGTCGACATCGTCATCGCCTGA

Upstream 100 bases:

>100_bases
CCGTGTTATGCTCACGCCGTCGCAAAGACGCTCGCACCAGGCCCCGACAAGGCCTTTCGCAATACGCAGTTGCGGCGAGT
GGTATTCCCAAGGAGAGCCC

Downstream 100 bases:

>100_bases
CATCGGCCGCTGGTAACCAGCGACACAACCCCTTTTCTGCTGGAGAGCATCACACCGGACGCCACGAACACCGCTTCGAT
AAGCTCCACCGCGCGGTGTG

Product: DeoR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 253; Mature: 253

Protein sequence:

>253_residues
MYPAERHKWLIDTARETGRVSVAEASTALGVVPETIRRDLDQLCNQKMLRRVHGGAIPIEFDLLGDQPLATRDSSAVTQK
EQIARAALSHLPSDKGSIILDAGSTTGRLASIMPSTRRFTVFTNSSPIASTVATHSNCDVHLLGGRLRPTTQATVGNVDA
IARLRVDVAFMGTNGISPTHGLSTPDADEVATKAAMVANAHHVVVLADSRKMGAESTMRFAELGDVDVIITDSGVTPHQV
EMLHKAGVDIVIA

Sequences:

>Translated_253_residues
MYPAERHKWLIDTARETGRVSVAEASTALGVVPETIRRDLDQLCNQKMLRRVHGGAIPIEFDLLGDQPLATRDSSAVTQK
EQIARAALSHLPSDKGSIILDAGSTTGRLASIMPSTRRFTVFTNSSPIASTVATHSNCDVHLLGGRLRPTTQATVGNVDA
IARLRVDVAFMGTNGISPTHGLSTPDADEVATKAAMVANAHHVVVLADSRKMGAESTMRFAELGDVDVIITDSGVTPHQV
EMLHKAGVDIVIA
>Mature_253_residues
MYPAERHKWLIDTARETGRVSVAEASTALGVVPETIRRDLDQLCNQKMLRRVHGGAIPIEFDLLGDQPLATRDSSAVTQK
EQIARAALSHLPSDKGSIILDAGSTTGRLASIMPSTRRFTVFTNSSPIASTVATHSNCDVHLLGGRLRPTTQATVGNVDA
IARLRVDVAFMGTNGISPTHGLSTPDADEVATKAAMVANAHHVVVLADSRKMGAESTMRFAELGDVDVIITDSGVTPHQV
EMLHKAGVDIVIA

Specific function: Repressor of the glycerol-3-phosphate regulon [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789829, Length=235, Percent_Identity=29.3617021276596, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1789059, Length=256, Percent_Identity=32.03125, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1789519, Length=253, Percent_Identity=29.2490118577075, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI226510968, Length=255, Percent_Identity=31.3725490196078, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1788069, Length=216, Percent_Identity=30.0925925925926, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1787540, Length=233, Percent_Identity=29.6137339055794, Blast_Score=85, Evalue=4e-18,
Organism=Escherichia coli, GI1790635, Length=252, Percent_Identity=27.3809523809524, Blast_Score=84, Evalue=7e-18,
Organism=Escherichia coli, GI87082344, Length=229, Percent_Identity=25.764192139738, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1789170, Length=235, Percent_Identity=29.3617021276596, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790753, Length=256, Percent_Identity=25.78125, Blast_Score=73, Evalue=2e-14,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 26931; Mature: 26931

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYPAERHKWLIDTARETGRVSVAEASTALGVVPETIRRDLDQLCNQKMLRRVHGGAIPIE
CCCCCCCEEEEECCCCCCCEEEECCCHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEE
FDLLGDQPLATRDSSAVTQKEQIARAALSHLPSDKGSIILDAGSTTGRLASIMPSTRRFT
EEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHCCCCEEEE
VFTNSSPIASTVATHSNCDVHLLGGRLRPTTQATVGNVDAIARLRVDVAFMGTNGISPTH
EEECCCCCHHHHHCCCCCCEEEECCCCCCCCCCCCCCHHHEEEEEEEEEEEECCCCCCCC
GLSTPDADEVATKAAMVANAHHVVVLADSRKMGAESTMRFAELGDVDVIITDSGVTPHQV
CCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHCCCEEEEEECCCCCHHHH
EMLHKAGVDIVIA
HHHHHCCCEEEEC
>Mature Secondary Structure
MYPAERHKWLIDTARETGRVSVAEASTALGVVPETIRRDLDQLCNQKMLRRVHGGAIPIE
CCCCCCCEEEEECCCCCCCEEEECCCHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEE
FDLLGDQPLATRDSSAVTQKEQIARAALSHLPSDKGSIILDAGSTTGRLASIMPSTRRFT
EEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHCCCCEEEE
VFTNSSPIASTVATHSNCDVHLLGGRLRPTTQATVGNVDAIARLRVDVAFMGTNGISPTH
EEECCCCCHHHHHCCCCCCEEEECCCCCCCCCCCCCCHHHEEEEEEEEEEEECCCCCCCC
GLSTPDADEVATKAAMVANAHHVVVLADSRKMGAESTMRFAELGDVDVIITDSGVTPHQV
CCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHCCCEEEEEECCCCCHHHH
EMLHKAGVDIVIA
HHHHHCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8752340; 10984043 [H]